Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6978078 . C A CCDS53740.1:NM_001159287.1:c.277Cta>Ata_NP_001152759.1:p.93L>I Homo sapiens triosephosphate isomerase 1 (TPI1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6up1 1 P60174 100.0 0.0 X-RAY
 2020-07-01 LEU A:59 A:55 6.0 0.035 S -74.6 138.7 6.0 0.035 0.0 HOH
 3.484
 O
 O
LEU B:59 B:55 7.0 0.041 S -71.5 140.8 7.0 0.041 0.0 IPA
HOH
 2.845
5.653
 O
O
 O2
O
6up5 1 P60174 100.0 0.0 X-RAY
 2020-07-01 LEU A:59 A:55 7.0 0.041 S -77.4 137.3 7.0 0.041 0.0 GOL
HOH
 3.089
4.717
 O
N
 C1
O
LEU B:59 B:55 8.0 0.047 S -81.8 145.7 8.0 0.047 0.0 IPA
HOH
 3.091
4.026
 O
C
 O2
O
4poc 1 P60174 100.0 0.0 X-RAY
 2015-01-14 LEU A:61 A:55 6.0 0.035 S -74.8 142.5 6.0 0.035 0.0 HOH
 2.750
 O
 O
LEU B:61 B:55 7.0 0.041 S -76.7 140.4 7.0 0.041 0.0 HOH
 6.131
 HA
 O
6c2g 1 P60174 99.6 0.0 X-RAY
 2018-03-21 LEU A:56 A:55 7.0 0.041 S -71.7 141.0 7.0 0.041 0.0 HOH
 5.902
 N
 O
LEU B:56 B:55 7.0 0.041 S -71.3 140.6 NA NA NA
LEU C:56 C:55 7.0 0.041 S -71.1 140.7 NA NA NA
LEU D:56 D:55 8.0 0.047 S -71.2 140.6 NA NA NA
4pod 1 P60174 99.6 0.0 X-RAY
 2015-01-14 LEU A:61 A:55 8.0 0.047 S -72.0 143.4 8.0 0.047 0.0 NA
HOH
 7.474
2.547
 O
O
 NA
O
LEU B:61 B:55 6.0 0.035 S -79.9 138.1 6.0 0.035 0.0 HOH
 3.506
 O
 O
1wyi 1 P60174 100.0 0.0 X-RAY
 2005-04-12 LEU A:57 A:55 7.0 0.041 S -75.7 136.7 7.0 0.041 0.0 HOH
 2.677
 CB
 O
LEU B:57 B:55 7.0 0.041 S -64.5 150.8 7.0 0.041 0.0 HOH
 3.683
 CD2
 O
2jk2 1 P60174 100.0 0.0 X-RAY
 2008-07-01 LEU A:57 A:55 7.0 0.041 S -69.6 136.5 7.0 0.041 0.0 HOH
 2.573
 O
 O
LEU B:57 B:55 6.0 0.035 S -71.9 138.2 6.0 0.035 0.0 HOH
 2.626
 O
 O
6up8 1 P60174 99.6 0.0 X-RAY
 2020-07-01 LEU A:59 A:55 8.0 0.047 S -74.9 148.1 8.0 0.047 0.0 HOH
 2.832
 O
 O
LEU B:59 B:55 6.0 0.035 S -81.5 143.3 6.0 0.035 0.0 HOH
 3.980
 C
 O
6upf 1 P60174 99.6 0.0 X-RAY
 2020-07-01 LEU A:59 A:55 7.0 0.041 S -77.2 143.3 7.0 0.041 0.0 HOH
 2.761
 O
 O
LEU B:59 B:55 9.0 0.053 S -80.6 136.9 9.0 0.053 0.0 HOH
 4.804
 C
 O
1hti 1 P60174 100.0 0.0 X-RAY
 1995-01-26 LEU A:55 A:55 10.0 0.059 S -99.0 145.3 10.0 0.059 0.0
LEU B:55 B:55 7.0 0.041 S -64.1 154.6 7.0 0.041 0.0
4zvj 1 P60174 99.6 0.0 X-RAY
 2016-03-09 LEU A:61 A:55 7.0 0.041 S -75.0 138.8 7.0 0.041 0.0 NA
HOH
 7.639
2.678
 O
O
 NA
O
LEU B:61 B:55 7.0 0.041 S -74.5 142.7 7.0 0.041 0.0 HOH
 2.695
 O
 O
2vom 1 P60174 99.6 0.0 X-RAY
 2008-06-17 LEU A:57 A:55 5.0 0.029 S -76.8 138.5 5.0 0.029 0.0 HOH
 7.496
 CD2
 O
LEU B:57 B:55 5.0 0.029 S -70.4 133.7 5.0 0.029 0.0 HOH
 2.607
 O
 O
LEU C:57 C:55 7.0 0.041 S -79.3 138.0 NA NA NA
LEU D:57 D:55 8.0 0.047 S -61.9 158.4 NA NA NA
4unk 1 P60174 99.6 0.0 X-RAY
 2015-02-04 LEU A:57 A:55 10.0 0.059 S -54.8 159.2 10.0 0.059 0.0 HOH
 4.509
 N
 O
LEU B:57 B:55 8.0 0.047 S -71.8 142.1 8.0 0.047 0.0 HOH
 4.153
 O
 O
4unl 1 P60174 99.6 0.0 X-RAY
 2015-02-04 LEU A:55 A:55 6.0 0.035 S -76.9 139.4 6.0 0.035 0.0 HOH
 2.691
 O
 O
LEU B:55 B:55 8.0 0.047 S -74.9 138.1 8.0 0.047 0.0 HOH
 2.850
 O
 O
4br1 1 P60174 100.0 0.0 X-RAY
 2013-06-12 LEU A:53 A:55 6.0 0.035 S -77.9 134.2 6.0 0.035 0.0 HOH
 2.816
 O
 O
LEU B:53 B:55 7.0 0.041 S -75.8 135.2 7.0 0.041 0.0 HOH
 2.510
 O
 O
6d43 1 P60174 100.0 0.0 X-RAY
 2018-05-16 LEU A:53 A:55 6.0 0.035 S -68.1 139.1 6.0 0.035 0.0 HOH
 2.944
 O
 O
6d43 2 P60174 100.0 0.0 X-RAY
 2018-05-16 LEU B:53 B:55 6.0 0.035 S -75.3 139.5 6.0 0.035 0.0 HOH
 3.911
 O
 O
1r2r 1 P00939 98.39 0.0 X-RAY
 2003-12-23 LEU A:55 A:55 8.0 0.047 S -77.4 140.3 8.0 0.047 0.0 HOH
 2.878
 O
 O
LEU B:55 B:55 8.0 0.047 S -76.1 145.7 8.0 0.047 0.0 HOH
 4.207
 C
 O
LEU C:55 C:55 7.0 0.041 S -83.3 144.7 NA NA NA
LEU D:55 D:55 7.0 0.041 S -77.2 141.3 NA NA NA
1r2s 1 P00939 98.39 0.0 X-RAY
 2003-12-23 LEU A:55 A:55 8.0 0.047 S -81.1 136.4 8.0 0.047 0.0
LEU B:55 B:55 9.0 0.053 S -81.1 135.3 9.0 0.053 0.0
LEU C:55 C:55 9.0 0.053 S -79.3 135.3 NA NA NA
LEU D:55 D:55 9.0 0.053 S -83.3 135.3 NA NA NA
1r2t 1 P00939 98.39 0.0 X-RAY
 2003-12-23 LEU A:55 A:55 7.0 0.041 S -76.8 141.2 7.0 0.041 0.0 HOH
 2.748
 O
 O
LEU B:55 B:55 7.0 0.041 S -77.6 137.9 7.0 0.041 0.0 HOH
 3.815
 O
 O
4owg 1 P00939 98.39 0.0 X-RAY
 2014-03-05 LEU A:55 A:55 7.0 0.041 S -74.3 141.2 7.0 0.041 0.0 HOH
 4.321
 O
 O
LEU B:55 B:55 7.0 0.041 S -76.0 140.7 7.0 0.041 0.0 HOH
 2.756
 O
 O
6nlh 1 P60174 99.59 0.0 X-RAY
 2019-06-19 LEU A:52 A:55 7.0 0.041 S -78.7 143.7 7.0 0.041 0.0 HOH
 2.813
 O
 O
LEU B:52 E:55 6.0 0.035 S -76.8 137.6 6.0 0.035 0.0 HOH
 2.632
 O
 O
LEU C:52 B:55 6.0 0.035 S -74.2 137.6 NA NA NA
LEU D:52 C:55 7.0 0.041 S -74.8 138.9 NA NA NA
LEU E:52 D:55 8.0 0.047 S -78.3 141.7 NA NA NA
LEU F:52 F:55 5.0 0.029 S -75.2 136.9 NA NA NA
LEU G:52 G:55 6.0 0.035 S -77.2 140.4 NA NA NA
LEU H:52 H:55 8.0 0.047 S -78.3 138.9 NA NA NA
1sw3 1 P00940 89.16 1e-162 X-RAY
 2004-08-24 LEU A:55 A:55 8.0 0.047 S -79.1 141.5 8.0 0.047 0.0 HOH
 3.087
 O
 O
LEU B:55 B:55 10.0 0.059 S -76.1 139.8 10.0 0.059 0.0 HOH
 2.959
 O
 O
1tph 1 P00940 89.39 7e-162 X-RAY
 1994-04-30 LEU A:54 1:55 8.0 0.047 S -73.6 145.7 8.0 0.047 0.0 HOH
 4.068
 C
 O
LEU B:54 2:55 9.0 0.053 S -76.1 141.1 9.0 0.053 0.0 HOH
 3.074
 O
 O
8tim 1 P00940 89.39 7e-162 X-RAY
 1999-02-16 LEU A:54 A:55 9.0 0.053 S -76.4 149.8 9.0 0.053 0.0 HOH
 7.233
 CD1
 O
LEU B:54 B:55 9.0 0.053 S -69.6 148.3 9.0 0.053 0.0
1sw7 1 P00940 88.35 8e-162 X-RAY
 2004-08-24 LEU A:55 A:55 6.0 0.035 S -73.3 141.8 6.0 0.035 0.0 HOH
 5.313
 O
 O
LEU B:55 B:55 6.0 0.035 S -65.0 139.5 6.0 0.035 0.0 HOH
 2.619
 O
 O
1spq 1 P00940 89.39 1e-161 X-RAY
 2004-08-24 LEU A:54 A:55 9.0 0.053 S -78.4 140.7 9.0 0.053 0.0 HOH
 2.796
 O
 O
LEU B:54 B:55 10.0 0.059 S -80.8 141.8 10.0 0.059 0.0 HOH
 4.047
 O
 O
1tpb 1 P00940 88.98 2e-161 X-RAY
 1995-02-14 LEU A:54 1:55 8.0 0.047 S -69.5 143.5 8.0 0.047 0.0 HOH
 3.172
 O
 O
LEU B:54 2:55 10.0 0.059 S -76.5 142.4 10.0 0.059 0.0 HOH
 3.977
 C
 O
1sw0 1 P00940 88.76 6e-161 X-RAY
 2004-08-24 LEU A:55 A:55 8.0 0.047 S -70.7 140.2 8.0 0.047 0.0 HOH
 2.668
 O
 O
LEU B:55 B:55 9.0 0.053 S -78.6 137.7 9.0 0.053 0.0 HOH
 2.589
 O
 O
1tpw 1 P00940 88.98 8e-161 X-RAY
 1995-04-20 LEU A:54 A:55 7.0 0.041 S -63.5 146.2 7.0 0.041 0.0 HOH
 3.034
 O
 O
LEU B:54 B:55 9.0 0.053 S -75.7 138.5 9.0 0.053 0.0 HOH
 6.824
 N
 O
1tpu 1 P00940 88.98 1e-160 X-RAY
 1995-04-20 LEU A:54 A:55 7.0 0.041 S -65.0 141.8 7.0 0.041 0.0 HOH
 4.125
 O
 O
LEU B:54 B:55 9.0 0.053 S -68.7 140.0 9.0 0.053 0.0 HOH
 3.442
 O
 O
4p61 1 P00940 88.76 2e-160 X-RAY
 2014-08-27 LEU A:55 A:55 9.0 0.053 S -75.6 138.5 9.0 0.053 0.0 HOH
 2.830
 O
 O
LEU B:55 B:55 9.0 0.053 S -74.6 138.2 9.0 0.053 0.0 HOH
 2.974
 O
 O
1tpc 1 P00940 88.57 2e-160 X-RAY
 1995-02-14 LEU A:54 1:55 7.0 0.041 S -66.6 143.2 7.0 0.041 0.0 HOH
 4.420
 O
 O
LEU B:54 2:55 9.0 0.053 S -76.3 137.0 9.0 0.053 0.0 HOH
 4.143
 C
 O
1ssd 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 LEU A:54 A:55 7.0 0.041 S -77.0 140.8 7.0 0.041 0.0 HOH
 4.691
 O
 O
LEU B:54 B:55 7.0 0.041 S -76.5 146.0 7.0 0.041 0.0 SO4
HOH
 4.691
8.098
 O
CD1
 O2
O
1ssg 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 LEU A:54 A:55 6.0 0.035 S -60.9 142.2 6.0 0.035 0.0 HOH
 5.416
 O
 O
LEU B:54 B:55 7.0 0.041 S -59.6 143.5 7.0 0.041 0.0 SO4
HOH
 4.296
6.829
 O
N
 O2
O
1sq7 1 P00940 88.98 4e-160 X-RAY
 2004-08-24 LEU A:54 A:55 6.0 0.035 S -69.3 140.7 6.0 0.035 0.0 HOH
 2.891
 O
 O
LEU B:54 B:55 6.0 0.035 S -71.0 148.4 6.0 0.035 0.0 HOH
 6.303
 N
 O
1tpv 1 P00940 88.57 1e-159 X-RAY
 1995-04-20 LEU A:54 A:55 8.0 0.047 S -76.9 143.4 8.0 0.047 0.0 HOH
 3.583
 O
 O
LEU B:54 B:55 8.0 0.047 S -71.3 140.3 8.0 0.047 0.0 HOH
 5.144
 N
 O
1su5 1 P00940 88.57 1e-159 X-RAY
 2004-08-24 LEU A:54 A:55 6.0 0.035 S -71.2 142.5 6.0 0.035 0.0 SO4
HOH
 4.424
4.842
 O
C
 O3
O
LEU B:54 B:55 6.0 0.035 S -75.4 146.4 6.0 0.035 0.0 SO4
SO4
HOH
 8.908
3.834
5.800
 CD2
O
O
 O2
O3
O
1tim 1 P00940 86.53 5e-158 X-RAY
 1976-10-15 LEU A:54 A:55 12.0 0.071 S -67.6 171.5 12.0 0.071 0.0
LEU B:54 B:55 7.0 0.041 S -44.0 139.3 7.0 0.041 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60174-f1 1 P60174 100.0 0.0 LEU A:56 A:56 6.0 0.035 S -71.5 139.4