Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 6978100 | . | C | A | CCDS53740.1:NM_001159287.1:c.299gCt>gAt_NP_001152759.1:p.100A>D | Homo sapiens triosephosphate isomerase 1 (TPI1), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6up1 | 1 | P60174 | 100.0 | 0.0 |
X-RAY |
2020-07-01 | ALA | A:66 | A:62 | 0.0 | 0.0 | E | -117.7 | 143.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.524 |
O |
O |
||
ALA | B:66 | B:62 | 0.0 | 0.0 | E | -119.6 | 134.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.448 |
O |
O |
|||||||||
6up5 | 1 | P60174 | 100.0 | 0.0 |
X-RAY |
2020-07-01 | ALA | A:66 | A:62 | 0.0 | 0.0 | E | -119.5 | 141.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.637 |
O |
O |
||
ALA | B:66 | B:62 | 1.0 | 0.009 | E | -122.6 | 139.9 | 1.0 | 0.009 | 0.0 |
HOH |
4.473 |
O |
O |
|||||||||
4poc | 1 | P60174 | 100.0 | 0.0 |
X-RAY |
2015-01-14 | ALA | A:68 | A:62 | 0.0 | 0.0 | E | -121.8 | 143.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.422 |
O |
O |
||
ALA | B:68 | B:62 | 1.0 | 0.009 | E | -123.0 | 147.0 | 1.0 | 0.009 | 0.0 |
HOH |
4.572 |
O |
O |
|||||||||
6c2g | 1 | P60174 | 99.6 | 0.0 |
X-RAY |
2018-03-21 | ALA | A:63 | A:62 | 0.0 | 0.0 | E | -119.0 | 144.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.613 |
O |
O |
||
ALA | B:63 | B:62 | 1.0 | 0.009 | E | -119.4 | 144.2 | NA | NA | NA | |||||||||||||
ALA | C:63 | C:62 | 0.0 | 0.0 | E | -117.9 | 144.0 | NA | NA | NA | |||||||||||||
ALA | D:63 | D:62 | 0.0 | 0.0 | E | -118.7 | 144.0 | NA | NA | NA | |||||||||||||
4pod | 1 | P60174 | 99.6 | 0.0 |
X-RAY |
2015-01-14 | ALA | A:68 | A:62 | 0.0 | 0.0 | E | -125.5 | 148.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.501 |
O |
O |
||
ALA | B:68 | B:62 | 0.0 | 0.0 | E | -123.1 | 149.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.491 |
O |
O |
|||||||||
1wyi | 1 | P60174 | 100.0 | 0.0 |
X-RAY |
2005-04-12 | ALA | A:64 | A:62 | 0.0 | 0.0 | E | -131.0 | 137.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.882 |
O |
O |
||
ALA | B:64 | B:62 | 0.0 | 0.0 | E | -136.8 | 127.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.565 |
O |
O |
|||||||||
2jk2 | 1 | P60174 | 100.0 | 0.0 |
X-RAY |
2008-07-01 | ALA | A:64 | A:62 | 0.0 | 0.0 | E | -122.0 | 144.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.500 |
O |
O |
||
ALA | B:64 | B:62 | 0.0 | 0.0 | E | -120.3 | 144.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.533 |
O |
O |
|||||||||
6up8 | 1 | P60174 | 99.6 | 0.0 |
X-RAY |
2020-07-01 | ALA | A:66 | A:62 | 0.0 | 0.0 | E | -114.8 | 140.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.536 |
O |
O |
||
ALA | B:66 | B:62 | 0.0 | 0.0 | E | -118.2 | 146.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.293 |
O |
O |
|||||||||
6upf | 1 | P60174 | 99.6 | 0.0 |
X-RAY |
2020-07-01 | ALA | A:66 | A:62 | 0.0 | 0.0 | E | -115.6 | 145.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.481 |
O |
O |
||
ALA | B:66 | B:62 | 0.0 | 0.0 | E | -116.1 | 142.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.505 |
O |
O |
|||||||||
1hti | 1 | P60174 | 100.0 | 0.0 |
X-RAY |
1995-01-26 | ALA | A:62 | A:62 | 0.0 | 0.0 | E | -142.3 | 148.2 | 0.0 | 0.0 | 0.0 | ||||||
ALA | B:62 | B:62 | 1.0 | 0.009 | E | -125.7 | 138.8 | 1.0 | 0.009 | 0.0 | |||||||||||||
4zvj | 1 | P60174 | 99.6 | 0.0 |
X-RAY |
2016-03-09 | ALA | A:68 | A:62 | 1.0 | 0.009 | E | -119.8 | 142.7 | 1.0 | 0.009 | 0.0 |
HOH |
4.477 |
O |
O |
||
ALA | B:68 | B:62 | 0.0 | 0.0 | E | -119.3 | 142.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.498 |
O |
O |
|||||||||
2vom | 1 | P60174 | 99.6 | 0.0 |
X-RAY |
2008-06-17 | ALA | A:64 | A:62 | 0.0 | 0.0 | E | -126.3 | 148.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.384 |
O |
O |
||
ALA | B:64 | B:62 | 0.0 | 0.0 | E | -125.0 | 150.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.335 |
O |
O |
|||||||||
ALA | C:64 | C:62 | 0.0 | 0.0 | E | -127.5 | 144.5 | NA | NA | NA | |||||||||||||
ALA | D:64 | D:62 | 0.0 | 0.0 | E | -130.6 | 147.9 | NA | NA | NA | |||||||||||||
4unk | 1 | P60174 | 99.6 | 0.0 |
X-RAY |
2015-02-04 | ALA | A:64 | A:62 | 0.0 | 0.0 | E | -120.5 | 144.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.536 |
O |
O |
||
ALA | B:64 | B:62 | 0.0 | 0.0 | E | -118.7 | 146.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.560 |
O |
O |
|||||||||
4unl | 1 | P60174 | 99.6 | 0.0 |
X-RAY |
2015-02-04 | ALA | A:62 | A:62 | 0.0 | 0.0 | E | -120.6 | 143.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.459 |
O |
O |
||
ALA | B:62 | B:62 | 1.0 | 0.009 | E | -119.5 | 145.3 | 1.0 | 0.009 | 0.0 |
HOH |
4.458 |
O |
O |
|||||||||
4br1 | 1 | P60174 | 100.0 | 0.0 |
X-RAY |
2013-06-12 | ALA | A:60 | A:62 | 0.0 | 0.0 | E | -119.5 | 144.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.442 |
O |
O |
||
ALA | B:60 | B:62 | 1.0 | 0.009 | E | -117.6 | 144.4 | 1.0 | 0.009 | 0.0 |
HOH |
4.532 |
O |
O |
|||||||||
6d43 | 1 | P60174 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | ALA | A:60 | A:62 | 0.0 | 0.0 | E | -123.1 | 138.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.509 |
O |
O |
||
6d43 | 2 | P60174 | 100.0 | 0.0 |
X-RAY |
2018-05-16 | ALA | B:60 | B:62 | 1.0 | 0.009 | E | -124.1 | 143.9 | 1.0 | 0.009 | 0.0 |
HOH |
4.418 |
O |
O |
||
1r2r | 1 | P00939 | 98.39 | 0.0 |
X-RAY |
2003-12-23 | ALA | A:62 | A:62 | 0.0 | 0.0 | E | -119.1 | 143.7 | 0.0 | 0.0 | 0.0 |
DMS HOH |
8.688 4.462 |
CB O |
O O |
||
ALA | B:62 | B:62 | 0.0 | 0.0 | E | -118.1 | 145.1 | 0.0 | 0.0 | 0.0 |
DMS HOH |
8.926 4.581 |
CB O |
O O |
|||||||||
ALA | C:62 | C:62 | 0.0 | 0.0 | E | -116.3 | 141.1 | NA | NA | NA | |||||||||||||
ALA | D:62 | D:62 | 0.0 | 0.0 | E | -118.8 | 145.4 | NA | NA | NA | |||||||||||||
1r2s | 1 | P00939 | 98.39 | 0.0 |
X-RAY |
2003-12-23 | ALA | A:62 | A:62 | 0.0 | 0.0 | E | -124.1 | 150.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.562 |
O |
O |
||
ALA | B:62 | B:62 | 0.0 | 0.0 | E | -120.0 | 151.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.357 |
O |
O |
|||||||||
ALA | C:62 | C:62 | 0.0 | 0.0 | E | -120.5 | 144.4 | NA | NA | NA | |||||||||||||
ALA | D:62 | D:62 | 1.0 | 0.009 | E | -120.4 | 153.6 | NA | NA | NA | |||||||||||||
1r2t | 1 | P00939 | 98.39 | 0.0 |
X-RAY |
2003-12-23 | ALA | A:62 | A:62 | 0.0 | 0.0 | E | -122.0 | 141.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.454 |
O |
O |
||
ALA | B:62 | B:62 | 0.0 | 0.0 | E | -125.2 | 143.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.396 |
O |
O |
|||||||||
4owg | 1 | P00939 | 98.39 | 0.0 |
X-RAY |
2014-03-05 | ALA | A:62 | A:62 | 0.0 | 0.0 | E | -116.5 | 147.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.534 |
O |
O |
||
ALA | B:62 | B:62 | 0.0 | 0.0 | E | -120.0 | 144.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.534 |
O |
O |
|||||||||
6nlh | 1 | P60174 | 99.59 | 0.0 |
X-RAY |
2019-06-19 | ALA | A:59 | A:62 | 0.0 | 0.0 | E | -126.0 | 139.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.514 |
O |
O |
||
ALA | B:59 | E:62 | 0.0 | 0.0 | E | -127.8 | 141.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.412 |
O |
O |
|||||||||
ALA | C:59 | B:62 | 0.0 | 0.0 | E | -121.5 | 143.7 | NA | NA | NA | |||||||||||||
ALA | D:59 | C:62 | 1.0 | 0.009 | E | -122.2 | 141.1 | NA | NA | NA | |||||||||||||
ALA | E:59 | D:62 | 1.0 | 0.009 | E | -123.5 | 142.2 | NA | NA | NA | |||||||||||||
ALA | F:59 | F:62 | 0.0 | 0.0 | E | -124.6 | 137.3 | NA | NA | NA | |||||||||||||
ALA | G:59 | G:62 | 0.0 | 0.0 | E | -119.0 | 147.0 | NA | NA | NA | |||||||||||||
ALA | H:59 | H:62 | 1.0 | 0.009 | E | -121.5 | 144.9 | NA | NA | NA | |||||||||||||
1sw3 | 1 | P00940 | 89.16 | 1e-162 |
X-RAY |
2004-08-24 | ALA | A:62 | A:62 | 1.0 | 0.009 | E | -123.2 | 142.4 | 1.0 | 0.009 | 0.0 |
HOH |
4.633 |
O |
O |
||
ALA | B:62 | B:62 | 0.0 | 0.0 | E | -121.9 | 141.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.542 |
O |
O |
|||||||||
1tph | 1 | P00940 | 89.39 | 7e-162 |
X-RAY |
1994-04-30 | ALA | A:61 | 1:62 | 1.0 | 0.009 | E | -124.6 | 143.1 | 1.0 | 0.009 | 0.0 |
HOH |
4.671 |
O |
O |
||
ALA | B:61 | 2:62 | 0.0 | 0.0 | E | -130.9 | 145.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.590 |
O |
O |
|||||||||
8tim | 1 | P00940 | 89.39 | 7e-162 |
X-RAY |
1999-02-16 | ALA | A:61 | A:62 | 3.0 | 0.026 | E | -121.7 | 141.1 | 3.0 | 0.026 | 0.0 |
HOH |
5.907 |
N |
O |
||
ALA | B:61 | B:62 | 1.0 | 0.009 | E | -117.8 | 140.4 | 1.0 | 0.009 | 0.0 |
HOH |
9.308 |
CA |
O |
|||||||||
1sw7 | 1 | P00940 | 88.35 | 8e-162 |
X-RAY |
2004-08-24 | ALA | A:62 | A:62 | 0.0 | 0.0 | E | -117.3 | 136.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.607 |
O |
O |
||
ALA | B:62 | B:62 | 0.0 | 0.0 | E | -115.4 | 138.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.710 |
O |
O |
|||||||||
1spq | 1 | P00940 | 89.39 | 1e-161 |
X-RAY |
2004-08-24 | ALA | A:61 | A:62 | 0.0 | 0.0 | E | -123.2 | 137.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.820 |
O |
O |
||
ALA | B:61 | B:62 | 1.0 | 0.009 | E | -124.4 | 139.6 | 1.0 | 0.009 | 0.0 |
HOH |
4.575 |
O |
O |
|||||||||
1tpb | 1 | P00940 | 88.98 | 2e-161 |
X-RAY |
1995-02-14 | ALA | A:61 | 1:62 | 0.0 | 0.0 | E | -124.4 | 146.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.646 |
O |
O |
||
ALA | B:61 | 2:62 | 0.0 | 0.0 | E | -127.2 | 149.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.549 |
O |
O |
|||||||||
1sw0 | 1 | P00940 | 88.76 | 6e-161 |
X-RAY |
2004-08-24 | ALA | A:62 | A:62 | 1.0 | 0.009 | E | -119.8 | 143.0 | 1.0 | 0.009 | 0.0 |
HOH |
4.814 |
O |
O |
||
ALA | B:62 | B:62 | 0.0 | 0.0 | E | -119.6 | 141.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.595 |
O |
O |
|||||||||
1tpw | 1 | P00940 | 88.98 | 8e-161 |
X-RAY |
1995-04-20 | ALA | A:61 | A:62 | 0.0 | 0.0 | E | -132.2 | 142.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.931 |
O |
O |
||
ALA | B:61 | B:62 | 0.0 | 0.0 | E | -122.3 | 150.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.823 |
O |
O |
|||||||||
1tpu | 1 | P00940 | 88.98 | 1e-160 |
X-RAY |
1995-04-20 | ALA | A:61 | A:62 | 0.0 | 0.0 | E | -123.6 | 138.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.819 |
O |
O |
||
ALA | B:61 | B:62 | 0.0 | 0.0 | E | -120.9 | 142.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.568 |
O |
O |
|||||||||
4p61 | 1 | P00940 | 88.76 | 2e-160 |
X-RAY |
2014-08-27 | ALA | A:62 | A:62 | 0.0 | 0.0 | E | -118.0 | 136.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.642 |
O |
O |
||
ALA | B:62 | B:62 | 0.0 | 0.0 | E | -115.9 | 140.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.668 |
O |
O |
|||||||||
1tpc | 1 | P00940 | 88.57 | 2e-160 |
X-RAY |
1995-02-14 | ALA | A:61 | 1:62 | 1.0 | 0.009 | E | -122.7 | 150.0 | 1.0 | 0.009 | 0.0 |
HOH |
4.726 |
O |
O |
||
ALA | B:61 | 2:62 | 0.0 | 0.0 | E | -125.1 | 143.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.629 |
O |
O |
|||||||||
1ssd | 1 | P00940 | 88.57 | 3e-160 |
X-RAY |
2004-08-24 | ALA | A:61 | A:62 | 1.0 | 0.009 | E | -123.8 | 140.3 | 1.0 | 0.009 | 0.0 |
HOH |
4.697 |
O |
O |
||
ALA | B:61 | B:62 | 0.0 | 0.0 | E | -121.8 | 139.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.757 |
O |
O |
|||||||||
1ssg | 1 | P00940 | 88.57 | 3e-160 |
X-RAY |
2004-08-24 | ALA | A:61 | A:62 | 0.0 | 0.0 | E | -123.0 | 141.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.858 |
O |
O |
||
ALA | B:61 | B:62 | 0.0 | 0.0 | E | -121.1 | 139.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.514 |
O |
O |
|||||||||
1sq7 | 1 | P00940 | 88.98 | 4e-160 |
X-RAY |
2004-08-24 | ALA | A:61 | A:62 | 0.0 | 0.0 | E | -128.0 | 137.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.644 |
O |
O |
||
ALA | B:61 | B:62 | 0.0 | 0.0 | E | -125.5 | 142.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.587 |
O |
O |
|||||||||
1tpv | 1 | P00940 | 88.57 | 1e-159 |
X-RAY |
1995-04-20 | ALA | A:61 | A:62 | 0.0 | 0.0 | E | -123.5 | 136.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.603 |
O |
O |
||
ALA | B:61 | B:62 | 0.0 | 0.0 | E | -119.9 | 141.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.500 |
O |
O |
|||||||||
1su5 | 1 | P00940 | 88.57 | 1e-159 |
X-RAY |
2004-08-24 | ALA | A:61 | A:62 | 0.0 | 0.0 | E | -116.8 | 131.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.915 |
O |
O |
||
ALA | B:61 | B:62 | 0.0 | 0.0 | E | -115.9 | 136.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.817 |
O |
O |
|||||||||
1tim | 1 | P00940 | 86.53 | 5e-158 |
X-RAY |
1976-10-15 | ALA | A:61 | A:62 | 3.0 | 0.026 | E | -116.4 | 141.3 | 3.0 | 0.026 | 0.0 | ||||||
ALA | B:61 | B:62 | 2.0 | 0.017 | E | -131.5 | 161.3 | 2.0 | 0.017 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p60174-f1 | 1 | P60174 | 100.0 | 0.0 | ALA | A:63 | A:63 | 0.0 | 0.0 | E | -116.3 | 150.4 |