Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6978338 . G A CCDS53740.1:NM_001159287.1:c.426gaG>gaA_NP_001152759.1:p.142E>E Homo sapiens triosephosphate isomerase 1 (TPI1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6up1 1 P60174 100.0 0.0 X-RAY
 2020-07-01 GLU A:108 A:104 19.0 0.1 -76.0 123.8 19.0 0.1 0.0 HOH
 2.640
 OE1
 O
GLU B:108 B:104 21.0 0.111 -70.7 126.4 20.0 0.105 0.006 A:P60174:0.005
 HOH
 2.540
 OE1
 O
6up5 1 P60174 100.0 0.0 X-RAY
 2020-07-01 GLU A:108 A:104 21.0 0.111 -70.8 123.8 21.0 0.111 0.0 GOL
HOH
 5.450
2.647
 N
OE1
 C1
O
GLU B:108 B:104 19.0 0.1 -68.9 125.9 18.0 0.095 0.005 A:P60174:0.005
 GOL
HOH
 4.979
2.658
 N
OE2
 O3
O
4poc 1 P60174 100.0 0.0 X-RAY
 2015-01-14 GLU A:110 A:104 19.0 0.1 -70.8 123.2 19.0 0.1 0.0 HOH
 2.665
 HA
 O
GLU B:110 B:104 18.0 0.095 -72.6 123.0 18.0 0.095 0.0 HOH
 2.642
 HA
 O
6c2g 1 P60174 99.6 0.0 X-RAY
 2018-03-21 GLU A:105 A:104 19.0 0.1 -68.5 119.6 18.0 0.095 0.005 C:P60174:0.005
 HOH
 2.642
 OE1
 O
GLU B:105 B:104 18.0 0.095 -68.9 120.1 NA NA NA
GLU C:105 C:104 18.0 0.095 -68.6 119.8 NA NA NA
GLU D:105 D:104 19.0 0.1 -68.9 120.2 NA NA NA
4pod 1 P60174 99.6 0.0 X-RAY
 2015-01-14 GLU A:110 A:104 20.0 0.105 -73.4 126.9 20.0 0.105 0.0 HOH
 2.631
 HA
 O
GLU B:110 B:104 19.0 0.1 -70.9 123.7 17.0 0.089 0.011 A:P60174:0.011
 HOH
 2.436
 OE2
 O
1wyi 1 P60174 100.0 0.0 X-RAY
 2005-04-12 GLU A:106 A:104 27.0 0.142 -72.7 129.0 23.0 0.121 0.021 B:P60174:0.021
 HOH
 2.689
 OE1
 O
GLU B:106 B:104 22.0 0.116 -70.2 121.7 22.0 0.116 0.0 HOH
 2.603
 OE2
 O
2jk2 1 P60174 100.0 0.0 X-RAY
 2008-07-01 GLU A:106 A:104 20.0 0.105 -68.0 122.7 19.0 0.1 0.005 B:P60174:0.005
 HOH
 2.673
 O
 O
GLU B:106 B:104 21.0 0.111 -69.0 126.0 20.0 0.105 0.006 A:P60174:0.005
 HOH
 2.889
 O
 O
6up8 1 P60174 99.6 0.0 X-RAY
 2020-07-01 GLU A:108 A:104 20.0 0.105 -74.8 120.3 20.0 0.105 0.0 IPA
HOH
 8.734
2.720
 OE2
OE1
 O2
O
GLU B:108 B:104 20.0 0.105 -68.0 123.9 20.0 0.105 0.0 IPA
HOH
 5.253
2.661
 OE2
OE2
 O2
O
6upf 1 P60174 99.6 0.0 X-RAY
 2020-07-01 GLU A:108 A:104 16.0 0.084 -71.0 122.6 16.0 0.084 0.0 HOH
 2.718
 OE2
 O
GLU B:108 B:104 18.0 0.095 -73.4 126.9 18.0 0.095 0.0 HOH
 2.682
 OE2
 O
1hti 1 P60174 100.0 0.0 X-RAY
 1995-01-26 GLU A:104 A:104 22.0 0.116 -75.2 117.1 19.0 0.1 0.016 B:P60174:0.016
GLU B:104 B:104 17.0 0.089 -59.4 117.5 15.0 0.079 0.01 A:P60174:0.011
4zvj 1 P60174 99.6 0.0 X-RAY
 2016-03-09 GLU A:110 A:104 18.0 0.095 -73.4 125.8 18.0 0.095 0.0 HOH
 2.619
 OE2
 O
GLU B:110 B:104 18.0 0.095 -70.8 125.2 16.0 0.084 0.011 A:P60174:0.011
 HOH
 2.617
 OE2
 O
2vom 1 P60174 99.6 0.0 X-RAY
 2008-06-17 ASP A:106 A:104 17.0 0.113 -64.1 118.8 17.0 0.113 0.0 HOH
 2.631
 OD1
 O
ASP B:106 B:104 18.0 0.12 -67.0 118.3 18.0 0.12 0.0 HOH
 2.714
 O
 O
ASP C:106 C:104 19.0 0.127 -67.2 121.0 NA NA NA
ASP D:106 D:104 19.0 0.127 -68.9 118.9 NA NA NA
4unk 1 P60174 99.6 0.0 X-RAY
 2015-02-04 GLU A:106 A:104 19.0 0.1 -69.7 125.5 19.0 0.1 0.0 HOH
 2.721
 O
 O
GLU B:106 B:104 16.0 0.084 -73.9 129.7 16.0 0.084 0.0 HOH
 2.708
 O
 O
4unl 1 P60174 99.6 0.0 X-RAY
 2015-02-04 GLU A:104 A:104 19.0 0.1 -70.6 125.2 17.0 0.089 0.011 B:P60174:0.011
 HOH
 2.694
 OE2
 O
GLU B:104 B:104 19.0 0.1 -68.8 125.7 18.0 0.095 0.005 A:P60174:0.005
 HOH
 2.616
 OE2
 O
4br1 1 P60174 100.0 0.0 X-RAY
 2013-06-12 GLU A:102 A:104 20.0 0.105 -68.2 125.2 19.0 0.1 0.005 B:P60174:0.005
 HOH
 2.587
 OE2
 O
GLU B:102 B:104 19.0 0.1 -67.6 126.3 18.0 0.095 0.005 A:P60174:0.005
 HOH
 2.623
 OE2
 O
6d43 1 P60174 100.0 0.0 X-RAY
 2018-05-16 GLU A:102 A:104 17.0 0.089 -72.1 120.7 17.0 0.089 0.0 HOH
 2.735
 OE2
 O
6d43 2 P60174 100.0 0.0 X-RAY
 2018-05-16 GLU B:102 B:104 18.0 0.095 -74.0 125.6 18.0 0.095 0.0 HOH
 2.711
 OE2
 O
1r2r 1 P00939 98.39 0.0 X-RAY
 2003-12-23 GLU A:104 A:104 20.0 0.105 -67.7 127.7 20.0 0.105 0.0 DMS
HOH
 3.944
2.668
 CG
O
 C2
O
GLU B:104 B:104 21.0 0.111 -64.4 128.8 21.0 0.111 0.0 MG
DMS
HOH
 5.836
7.092
2.647
 O
N
OE2
 MG
S
O
GLU C:104 C:104 18.0 0.095 -72.9 128.9 NA NA NA
GLU D:104 D:104 24.0 0.126 -63.8 128.0 NA NA NA
1r2s 1 P00939 98.39 0.0 X-RAY
 2003-12-23 GLU A:104 A:104 22.0 0.116 -76.5 127.9 22.0 0.116 0.0 HOH
 2.783
 OE2
 O
GLU B:104 B:104 23.0 0.121 -71.8 128.5 23.0 0.121 0.0 HOH
 2.914
 OE1
 O
GLU C:104 C:104 22.0 0.116 -75.5 128.2 NA NA NA
GLU D:104 D:104 23.0 0.121 -71.1 128.5 NA NA NA
1r2t 1 P00939 98.39 0.0 X-RAY
 2003-12-23 GLU A:104 A:104 19.0 0.1 -70.2 122.2 17.0 0.089 0.011 B:P00939:0.011
 HOH
 2.537
 OE2
 O
GLU B:104 B:104 19.0 0.1 -71.1 123.5 17.0 0.089 0.011 A:P00939:0.011
 HOH
 2.674
 OE2
 O
4owg 1 P00939 98.39 0.0 X-RAY
 2014-03-05 GLU A:104 A:104 17.0 0.089 -72.3 124.6 17.0 0.089 0.0 HOH
 2.695
 OE2
 O
GLU B:104 B:104 18.0 0.095 -72.8 126.6 17.0 0.089 0.006 A:P00939:0.005
 HOH
 2.682
 OE2
 O
6nlh 1 P60174 99.59 0.0 X-RAY
 2019-06-19 GLU A:101 A:104 19.0 0.1 -75.4 121.6 15.0 0.079 0.021 B:P60174:0.021
 NA
HOH
 7.389
2.401
 O
OE2
 NA
O
GLU B:101 E:104 18.0 0.095 -73.9 122.0 16.0 0.084 0.011 A:P60174:0.011
 HOH
 2.276
 HA
 O
GLU C:101 B:104 19.0 0.1 -70.2 115.8 NA NA NA
GLU D:101 C:104 18.0 0.095 -68.7 123.1 NA NA NA
GLU E:101 D:104 18.0 0.095 -70.9 120.8 NA NA NA
GLU F:101 F:104 18.0 0.095 -68.8 124.7 NA NA NA
GLU G:101 G:104 17.0 0.089 -72.2 119.3 NA NA NA
GLU H:101 H:104 21.0 0.111 -70.9 127.1 NA NA NA
1sw3 1 P00940 89.16 1e-162 X-RAY
 2004-08-24 GLU A:104 A:104 18.0 0.095 -72.5 126.0 16.0 0.084 0.011 B:P00940:0.011
 HOH
 2.653
 OE1
 O
GLU B:104 B:104 19.0 0.1 -75.9 126.7 18.0 0.095 0.005 A:P00940:0.005
 HOH
 2.586
 OE1
 O
1tph 1 P00940 89.39 7e-162 X-RAY
 1994-04-30 GLU A:103 1:104 19.0 0.1 -75.9 119.0 17.0 0.089 0.011 B:P00940:0.011
 HOH
 2.615
 OE2
 O
GLU B:103 2:104 19.0 0.1 -68.5 129.2 19.0 0.1 0.0 HOH
 2.715
 OE2
 O
8tim 1 P00940 89.39 7e-162 X-RAY
 1999-02-16 GLU A:103 A:104 22.0 0.116 -60.9 133.6 22.0 0.116 0.0 HOH
 3.047
 OE2
 O
GLU B:103 B:104 21.0 0.111 -67.5 131.0 20.0 0.105 0.006 A:P00940:0.005
 HOH
 3.323
 OE2
 O
1sw7 1 P00940 88.35 8e-162 X-RAY
 2004-08-24 GLU A:104 A:104 18.0 0.095 -71.3 126.0 13.0 0.068 0.027 B:P00940:0.026
 HOH
 2.697
 OE2
 O
GLU B:104 B:104 18.0 0.095 -75.0 127.8 13.0 0.068 0.027 A:P00940:0.026
 HOH
 2.600
 OE2
 O
1spq 1 P00940 89.39 1e-161 X-RAY
 2004-08-24 GLU A:103 A:104 22.0 0.116 -73.8 127.2 18.0 0.095 0.021 B:P00940:0.021
 PEG
HOH
 5.436
2.548
 N
O
 O2
O
GLU B:103 B:104 21.0 0.111 -75.0 129.6 20.0 0.105 0.006 A:P00940:0.005
 PEG
HOH
 5.371
2.814
 N
OE1
 C2
O
1tpb 1 P00940 88.98 2e-161 X-RAY
 1995-02-14 GLU A:103 1:104 18.0 0.095 -75.4 123.0 16.0 0.084 0.011 B:P00940:0.011
 HOH
 2.834
 OE1
 O
GLU B:103 2:104 21.0 0.111 -73.8 130.5 19.0 0.1 0.011 A:P00940:0.011
 HOH
 2.694
 O
 O
1sw0 1 P00940 88.76 6e-161 X-RAY
 2004-08-24 GLU A:104 A:104 18.0 0.095 -74.7 122.5 17.0 0.089 0.006 B:P00940:0.005
 HOH
 2.692
 OE2
 O
GLU B:104 B:104 20.0 0.105 -71.9 126.3 20.0 0.105 0.0 HOH
 2.787
 O
 O
1tpw 1 P00940 88.98 8e-161 X-RAY
 1995-04-20 GLU A:103 A:104 17.0 0.089 -74.9 117.4 17.0 0.089 0.0 HOH
 2.848
 O
 O
GLU B:103 B:104 17.0 0.089 -74.3 131.3 17.0 0.089 0.0 HOH
 2.804
 O
 O
1tpu 1 P00940 88.98 1e-160 X-RAY
 1995-04-20 GLU A:103 A:104 16.0 0.084 -73.4 123.5 16.0 0.084 0.0 HOH
 2.954
 OE1
 O
GLU B:103 B:104 18.0 0.095 -68.9 134.4 18.0 0.095 0.0 HOH
 2.850
 OE1
 O
4p61 1 P00940 88.76 2e-160 X-RAY
 2014-08-27 GLU A:104 A:104 18.0 0.095 -67.6 125.7 18.0 0.095 0.0 HOH
 2.760
 OE2
 O
GLU B:104 B:104 18.0 0.095 -67.3 125.1 18.0 0.095 0.0 HOH
 2.677
 OE2
 O
1tpc 1 P00940 88.57 2e-160 X-RAY
 1995-02-14 GLU A:103 1:104 20.0 0.105 -68.9 121.4 20.0 0.105 0.0 HOH
 2.633
 OE2
 O
GLU B:103 2:104 18.0 0.095 -63.7 128.0 18.0 0.095 0.0 HOH
 2.787
 OE1
 O
1ssd 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 GLU A:103 A:104 19.0 0.1 -69.3 127.4 14.0 0.074 0.026 B:P00940:0.026
 HOH
 2.501
 OE2
 O
GLU B:103 B:104 20.0 0.105 -72.3 129.6 14.0 0.074 0.031 A:P00940:0.032
 HOH
 2.561
 OE2
 O
1ssg 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 GLU A:103 A:104 20.0 0.105 -63.0 124.8 14.0 0.074 0.031 B:P00940:0.032
 SO4
HOH
 6.383
2.657
 O
OE2
 O3
O
GLU B:103 B:104 19.0 0.1 -74.0 127.0 12.0 0.063 0.037 A:P00940:0.037
 SO4
HOH
 6.644
2.629
 N
O
 O1
O
1sq7 1 P00940 88.98 4e-160 X-RAY
 2004-08-24 GLU A:103 A:104 15.0 0.079 -74.9 121.4 11.0 0.058 0.021 B:P00940:0.021
 HOH
 2.477
 O
 O
GLU B:103 B:104 15.0 0.079 -73.7 118.9 10.0 0.053 0.026 A:P00940:0.026
 HOH
 2.560
 OE2
 O
1tpv 1 P00940 88.57 1e-159 X-RAY
 1995-04-20 GLU A:103 A:104 18.0 0.095 -73.7 122.3 18.0 0.095 0.0 HOH
 2.735
 O
 O
GLU B:103 B:104 18.0 0.095 -71.5 133.8 18.0 0.095 0.0 HOH
 2.804
 OE2
 O
1su5 1 P00940 88.57 1e-159 X-RAY
 2004-08-24 GLU A:103 A:104 17.0 0.089 -78.5 121.6 13.0 0.068 0.021 B:P00940:0.021
 HOH
 2.418
 OE2
 O
GLU B:103 B:104 18.0 0.095 -75.2 129.0 13.0 0.068 0.027 A:P00940:0.026
 HOH
 2.246
 OE2
 O
1tim 1 P00940 86.53 5e-158 X-RAY
 1976-10-15 GLU A:103 A:104 23.0 0.121 -31.2 159.7 23.0 0.121 0.0
GLU B:103 B:104 27.0 0.142 -109.8 139.9 20.0 0.105 0.037 A:P00940:0.037

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60174-f1 1 P60174 100.0 0.0 GLU A:105 A:105 16.0 0.084 -68.0 117.8