Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6978438 . T A CCDS53740.1:NM_001159287.1:c.452gTg>gAg_NP_001152759.1:p.151V>E Homo sapiens triosephosphate isomerase 1 (TPI1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6up1 1 P60174 100.0 0.0 X-RAY
 2020-07-01 VAL A:117 A:113 0.0 0.0 H -59.7 -47.0 0.0 0.0 0.0 HOH
 5.063
 O
 O
VAL B:117 B:113 1.0 0.006 H -60.4 -48.9 1.0 0.006 0.0 HOH
 4.877
 O
 O
6up5 1 P60174 100.0 0.0 X-RAY
 2020-07-01 VAL A:117 A:113 1.0 0.006 H -59.7 -45.6 1.0 0.006 0.0 HOH
 5.085
 O
 O
VAL B:117 B:113 0.0 0.0 H -56.9 -52.0 0.0 0.0 0.0 HOH
 4.825
 O
 O
4poc 1 P60174 100.0 0.0 X-RAY
 2015-01-14 VAL A:119 A:113 0.0 0.0 H -61.7 -47.8 0.0 0.0 0.0 HOH
 4.854
 HG12
 O
VAL B:119 B:113 0.0 0.0 H -63.1 -47.9 0.0 0.0 0.0 HOH
 4.846
 HG12
 O
6c2g 1 P60174 99.6 0.0 X-RAY
 2018-03-21 VAL A:114 A:113 1.0 0.006 H -56.0 -51.7 1.0 0.006 0.0 HOH
 5.287
 O
 O
VAL B:114 B:113 0.0 0.0 H -55.5 -52.0 NA NA NA
VAL C:114 C:113 0.0 0.0 H -55.5 -51.8 NA NA NA
VAL D:114 D:113 0.0 0.0 H -55.7 -51.9 NA NA NA
4pod 1 P60174 99.6 0.0 X-RAY
 2015-01-14 VAL A:119 A:113 1.0 0.006 H -62.6 -46.8 1.0 0.006 0.0 HOH
 4.702
 HG12
 O
VAL B:119 B:113 0.0 0.0 H -58.5 -48.7 0.0 0.0 0.0 HOH
 4.979
 O
 O
1wyi 1 P60174 100.0 0.0 X-RAY
 2005-04-12 VAL A:115 A:113 1.0 0.006 H -61.0 -50.1 1.0 0.006 0.0 HOH
 3.172
 CG2
 O
VAL B:115 B:113 0.0 0.0 H -59.0 -48.1 0.0 0.0 0.0 HOH
 4.107
 CG2
 O
2jk2 1 P60174 100.0 0.0 X-RAY
 2008-07-01 VAL A:115 A:113 0.0 0.0 H -58.9 -49.6 0.0 0.0 0.0 HOH
 5.125
 O
 O
VAL B:115 B:113 0.0 0.0 H -56.6 -51.3 0.0 0.0 0.0 HOH
 4.773
 O
 O
6up8 1 P60174 99.6 0.0 X-RAY
 2020-07-01 VAL A:117 A:113 0.0 0.0 H -60.1 -49.8 0.0 0.0 0.0 IPA
HOH
 5.069
6.118
 O
N
 O2
O
VAL B:117 B:113 0.0 0.0 H -54.3 -51.6 0.0 0.0 0.0 IPA
HOH
 6.607
4.945
 C
O
 O2
O
6upf 1 P60174 99.6 0.0 X-RAY
 2020-07-01 VAL A:117 A:113 1.0 0.006 H -60.6 -49.7 1.0 0.006 0.0 HOH
 4.829
 N
 O
VAL B:117 B:113 0.0 0.0 H -56.9 -49.3 0.0 0.0 0.0 HOH
 5.019
 O
 O
1hti 1 P60174 100.0 0.0 X-RAY
 1995-01-26 VAL A:113 A:113 0.0 0.0 H -65.1 -49.1 0.0 0.0 0.0
VAL B:113 B:113 0.0 0.0 H -54.1 -53.9 0.0 0.0 0.0
4zvj 1 P60174 99.6 0.0 X-RAY
 2016-03-09 VAL A:119 A:113 0.0 0.0 H -61.5 -47.0 0.0 0.0 0.0 HOH
 4.838
 HG12
 O
VAL B:119 B:113 0.0 0.0 H -58.2 -47.0 0.0 0.0 0.0 HOH
 4.775
 HG12
 O
2vom 1 P60174 99.6 0.0 X-RAY
 2008-06-17 VAL A:115 A:113 0.0 0.0 H -61.5 -48.9 0.0 0.0 0.0 HOH
 4.918
 O
 O
VAL B:115 B:113 0.0 0.0 H -62.8 -49.1 0.0 0.0 0.0 HOH
 5.084
 O
 O
VAL C:115 C:113 0.0 0.0 H -59.4 -53.1 NA NA NA
VAL D:115 D:113 0.0 0.0 H -61.6 -50.1 NA NA NA
4unk 1 P60174 99.6 0.0 X-RAY
 2015-02-04 VAL A:115 A:113 0.0 0.0 H -61.2 -48.4 0.0 0.0 0.0 HOH
 4.897
 O
 O
VAL B:115 B:113 0.0 0.0 H -59.4 -46.7 0.0 0.0 0.0 HOH
 4.991
 O
 O
4unl 1 P60174 99.6 0.0 X-RAY
 2015-02-04 VAL A:113 A:113 0.0 0.0 H -61.2 -48.9 0.0 0.0 0.0 HOH
 5.115
 O
 O
VAL B:113 B:113 0.0 0.0 H -58.3 -50.6 0.0 0.0 0.0 HOH
 5.162
 O
 O
4br1 1 P60174 100.0 0.0 X-RAY
 2013-06-12 VAL A:111 A:113 1.0 0.006 H -60.0 -49.3 1.0 0.006 0.0 HOH
 5.000
 O
 O
VAL B:111 B:113 0.0 0.0 H -57.8 -45.9 0.0 0.0 0.0 HOH
 5.168
 O
 O
6d43 1 P60174 100.0 0.0 X-RAY
 2018-05-16 VAL A:111 A:113 0.0 0.0 H -57.8 -47.8 0.0 0.0 0.0 HOH
 5.095
 O
 O
6d43 2 P60174 100.0 0.0 X-RAY
 2018-05-16 VAL B:111 B:113 0.0 0.0 H -63.2 -49.8 0.0 0.0 0.0 HOH
 4.874
 O
 O
1r2r 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:113 A:113 0.0 0.0 H -56.7 -54.3 0.0 0.0 0.0 HOH
 5.042
 O
 O
VAL B:113 B:113 1.0 0.006 H -59.3 -47.8 1.0 0.006 0.0 HOH
 4.988
 O
 O
VAL C:113 C:113 0.0 0.0 H -58.7 -50.6 NA NA NA
VAL D:113 D:113 0.0 0.0 H -58.0 -50.6 NA NA NA
1r2s 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:113 A:113 1.0 0.006 H -62.9 -47.0 1.0 0.006 0.0 HOH
 7.110
 CG2
 O
VAL B:113 B:113 0.0 0.0 H -60.0 -50.5 0.0 0.0 0.0 HOH
 7.207
 CG2
 O
VAL C:113 C:113 1.0 0.006 H -60.8 -46.6 NA NA NA
VAL D:113 D:113 1.0 0.006 H -62.0 -45.4 NA NA NA
1r2t 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:113 A:113 0.0 0.0 H -60.2 -50.8 0.0 0.0 0.0 HOH
 5.238
 O
 O
VAL B:113 B:113 0.0 0.0 H -61.8 -48.6 0.0 0.0 0.0 HOH
 4.892
 O
 O
4owg 1 P00939 98.39 0.0 X-RAY
 2014-03-05 VAL A:113 A:113 1.0 0.006 H -59.0 -45.8 1.0 0.006 0.0 HOH
 6.061
 C
 O
VAL B:113 B:113 0.0 0.0 H -59.7 -45.4 0.0 0.0 0.0 HOH
 6.081
 C
 O
6nlh 1 P60174 99.59 0.0 X-RAY
 2019-06-19 VAL A:110 A:113 1.0 0.006 H -61.3 -50.3 1.0 0.006 0.0 NA
HOH
 6.164
5.043
 HG21
HG12
 NA
O
VAL B:110 E:113 0.0 0.0 H -58.3 -47.4 0.0 0.0 0.0 HOH
 4.701
 HG12
 O
VAL C:110 B:113 0.0 0.0 H -60.0 -50.8 NA NA NA
VAL D:110 C:113 0.0 0.0 H -59.3 -46.4 NA NA NA
VAL E:110 D:113 0.0 0.0 H -64.8 -49.0 NA NA NA
VAL F:110 F:113 0.0 0.0 H -54.2 -49.4 NA NA NA
VAL G:110 G:113 0.0 0.0 H -61.2 -45.6 NA NA NA
VAL H:110 H:113 0.0 0.0 H -56.6 -49.0 NA NA NA
1sw3 1 P00940 89.16 1e-162 X-RAY
 2004-08-24 VAL A:113 A:113 0.0 0.0 H -55.6 -48.3 0.0 0.0 0.0 HOH
 5.058
 O
 O
VAL B:113 B:113 0.0 0.0 H -59.8 -51.6 0.0 0.0 0.0 HOH
 5.058
 O
 O
1tph 1 P00940 89.39 7e-162 X-RAY
 1994-04-30 VAL A:112 1:113 0.0 0.0 H -57.8 -50.4 0.0 0.0 0.0 HOH
 5.006
 O
 O
VAL B:112 2:113 0.0 0.0 H -59.9 -47.5 0.0 0.0 0.0 HOH
 5.095
 O
 O
8tim 1 P00940 89.39 7e-162 X-RAY
 1999-02-16 VAL A:112 A:113 2.0 0.013 H -60.2 -56.9 2.0 0.013 0.0 HOH
 9.487
 N
 O
VAL B:112 B:113 0.0 0.0 H -58.2 -51.6 0.0 0.0 0.0 HOH
 5.060
 O
 O
1sw7 1 P00940 88.35 8e-162 X-RAY
 2004-08-24 VAL A:113 A:113 0.0 0.0 H -62.2 -46.6 0.0 0.0 0.0 HOH
 4.939
 O
 O
VAL B:113 B:113 0.0 0.0 H -63.2 -54.6 0.0 0.0 0.0 HOH
 6.228
 O
 O
1spq 1 P00940 89.39 1e-161 X-RAY
 2004-08-24 VAL A:112 A:113 1.0 0.006 H -59.1 -46.7 1.0 0.006 0.0 HOH
 5.150
 O
 O
VAL B:112 B:113 1.0 0.006 H -59.4 -48.5 1.0 0.006 0.0 HOH
 5.214
 O
 O
1tpb 1 P00940 88.98 2e-161 X-RAY
 1995-02-14 VAL A:112 1:113 0.0 0.0 H -58.5 -48.6 0.0 0.0 0.0 HOH
 4.834
 O
 O
VAL B:112 2:113 0.0 0.0 H -61.5 -49.3 0.0 0.0 0.0 HOH
 6.121
 C
 O
1sw0 1 P00940 88.76 6e-161 X-RAY
 2004-08-24 VAL A:113 A:113 1.0 0.006 H -56.4 -47.3 1.0 0.006 0.0 HOH
 5.145
 O
 O
VAL B:113 B:113 0.0 0.0 H -64.5 -49.0 0.0 0.0 0.0 HOH
 4.955
 O
 O
1tpw 1 P00940 88.98 8e-161 X-RAY
 1995-04-20 VAL A:112 A:113 0.0 0.0 H -54.7 -48.9 0.0 0.0 0.0 HOH
 5.089
 O
 O
VAL B:112 B:113 0.0 0.0 H -61.6 -49.9 0.0 0.0 0.0 HOH
 5.041
 O
 O
1tpu 1 P00940 88.98 1e-160 X-RAY
 1995-04-20 VAL A:112 A:113 0.0 0.0 H -61.5 -47.4 0.0 0.0 0.0 HOH
 5.041
 O
 O
VAL B:112 B:113 0.0 0.0 H -57.1 -47.1 0.0 0.0 0.0 HOH
 6.133
 C
 O
4p61 1 P00940 88.76 2e-160 X-RAY
 2014-08-27 VAL A:113 A:113 1.0 0.006 H -60.4 -49.3 1.0 0.006 0.0 HOH
 5.056
 O
 O
VAL B:113 B:113 0.0 0.0 H -59.4 -49.0 0.0 0.0 0.0 HOH
 5.064
 O
 O
1tpc 1 P00940 88.57 2e-160 X-RAY
 1995-02-14 VAL A:112 1:113 0.0 0.0 H -61.5 -49.2 0.0 0.0 0.0 HOH
 4.908
 O
 O
VAL B:112 2:113 0.0 0.0 H -58.0 -50.0 0.0 0.0 0.0 HOH
 4.998
 O
 O
1ssd 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 VAL A:112 A:113 0.0 0.0 H -67.4 -45.0 0.0 0.0 0.0 HOH
 7.137
 CG2
 O
VAL B:112 B:113 0.0 0.0 H -68.5 -48.1 0.0 0.0 0.0 HOH
 5.948
 N
 O
1ssg 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 VAL A:112 A:113 0.0 0.0 H -65.7 -44.9 0.0 0.0 0.0 HOH
 6.970
 CG2
 O
VAL B:112 B:113 0.0 0.0 H -60.6 -49.2 0.0 0.0 0.0 GOL
HOH
 5.956
6.469
 C
O
 O3
O
1sq7 1 P00940 88.98 4e-160 X-RAY
 2004-08-24 VAL A:112 A:113 0.0 0.0 H -65.9 -43.4 0.0 0.0 0.0 HOH
 4.957
 O
 O
VAL B:112 B:113 0.0 0.0 H -65.3 -46.8 0.0 0.0 0.0 HOH
 4.888
 O
 O
1tpv 1 P00940 88.57 1e-159 X-RAY
 1995-04-20 VAL A:112 A:113 0.0 0.0 H -56.4 -47.4 0.0 0.0 0.0 HOH
 4.923
 O
 O
VAL B:112 B:113 0.0 0.0 H -56.4 -54.4 0.0 0.0 0.0 HOH
 6.003
 C
 O
1su5 1 P00940 88.57 1e-159 X-RAY
 2004-08-24 VAL A:112 A:113 0.0 0.0 H -68.3 -42.4 0.0 0.0 0.0 SO4
GOL
HOH
 6.322
9.028
4.888
 C
N
O
 O1
O1
O
VAL B:112 B:113 0.0 0.0 H -63.4 -48.0 0.0 0.0 0.0 SO4
HOH
 6.325
5.048
 C
O
 O1
O
1tim 1 P00940 86.53 5e-158 X-RAY
 1976-10-15 VAL A:112 A:113 3.0 0.019 H -42.0 -60.4 3.0 0.019 0.0
VAL B:112 B:113 0.0 0.0 H -44.2 -45.2 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60174-f1 1 P60174 100.0 0.0 VAL A:114 A:114 0.0 0.0 H -60.4 -50.1