Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6978453 . C A CCDS53740.1:NM_001159287.1:c.467gCa>gAa_NP_001152759.1:p.156A>E Homo sapiens triosephosphate isomerase 1 (TPI1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6up1 1 P60174 100.0 0.0 X-RAY
 2020-07-01 ALA A:122 A:118 86.0 0.748 H -60.5 -29.5 86.0 0.748 0.0 HOH
 2.873
 O
 O
ALA B:122 B:118 83.0 0.722 H -55.7 -36.7 83.0 0.722 0.0 HOH
 3.084
 O
 O
6up5 1 P60174 100.0 0.0 X-RAY
 2020-07-01 ALA A:122 A:118 87.0 0.757 H -60.5 -34.7 87.0 0.757 0.0 HOH
 2.700
 O
 O
ALA B:122 B:118 81.0 0.704 H -54.9 -37.9 81.0 0.704 0.0 HOH
 3.428
 N
 O
4poc 1 P60174 100.0 0.0 X-RAY
 2015-01-14 ALA A:124 A:118 79.0 0.687 H -63.7 -31.6 79.0 0.687 0.0 HOH
 2.797
 HB2
 O
ALA B:124 B:118 78.0 0.678 H -64.7 -29.3 78.0 0.678 0.0 HOH
 3.052
 HB2
 O
6c2g 1 P60174 99.6 0.0 X-RAY
 2018-03-21 ALA A:119 A:118 82.0 0.713 H -61.6 -28.4 82.0 0.713 0.0 HOH
 5.119
 N
 O
ALA B:119 B:118 82.0 0.713 H -61.8 -28.5 NA NA NA
ALA C:119 C:118 75.0 0.652 H -61.7 -28.6 NA NA NA
ALA D:119 D:118 82.0 0.713 H -61.3 -28.7 NA NA NA
4pod 1 P60174 99.6 0.0 X-RAY
 2015-01-14 ALA A:124 A:118 86.0 0.748 H -60.9 -29.6 86.0 0.748 0.0 HOH
 2.509
 HB3
 O
ALA B:124 B:118 79.0 0.687 H -62.9 -30.4 79.0 0.687 0.0 HOH
 2.602
 HB2
 O
1wyi 1 P60174 100.0 0.0 X-RAY
 2005-04-12 ALA A:120 A:118 87.0 0.757 H -57.5 -34.3 87.0 0.757 0.0 HOH
 2.836
 CB
 O
ALA B:120 B:118 80.0 0.696 H -60.4 -18.5 80.0 0.696 0.0 HOH
 2.526
 O
 O
2jk2 1 P60174 100.0 0.0 X-RAY
 2008-07-01 ALA A:120 A:118 76.0 0.661 H -61.0 -34.4 76.0 0.661 0.0 HOH
 2.673
 O
 O
ALA B:120 B:118 82.0 0.713 H -56.3 -37.4 82.0 0.713 0.0 HOH
 3.259
 O
 O
6up8 1 P60174 99.6 0.0 X-RAY
 2020-07-01 ALA A:122 A:118 84.0 0.73 H -55.8 -35.1 84.0 0.73 0.0 IPA
HOH
 3.828
2.906
 N
O
 C1
O
ALA B:122 B:118 84.0 0.73 H -49.3 -39.4 84.0 0.73 0.0 IPA
HOH
 4.072
3.347
 CB
N
 C2
O
6upf 1 P60174 99.6 0.0 X-RAY
 2020-07-01 ALA A:122 A:118 82.0 0.713 H -63.6 -30.1 82.0 0.713 0.0 HOH
 3.518
 CA
 O
ALA B:122 B:118 81.0 0.704 H -63.2 -29.5 81.0 0.704 0.0 HOH
 3.279
 CA
 O
1hti 1 P60174 100.0 0.0 X-RAY
 1995-01-26 ALA A:118 A:118 81.0 0.704 H -47.0 -35.4 81.0 0.704 0.0
ALA B:118 B:118 81.0 0.704 H -60.4 -23.2 81.0 0.704 0.0
4zvj 1 P60174 99.6 0.0 X-RAY
 2016-03-09 ALA A:124 A:118 74.0 0.643 H -64.3 -27.5 74.0 0.643 0.0 HOH
 2.742
 HB2
 O
ALA B:124 B:118 81.0 0.704 H -61.3 -32.1 81.0 0.704 0.0 HOH
 2.759
 HB1
 O
2vom 1 P60174 99.6 0.0 X-RAY
 2008-06-17 ALA A:120 A:118 76.0 0.661 H -63.4 -30.8 76.0 0.661 0.0 HOH
 2.771
 O
 O
ALA B:120 B:118 82.0 0.713 H -62.7 -29.9 82.0 0.713 0.0 HOH
 3.230
 CA
 O
ALA C:120 C:118 77.0 0.67 H -63.9 -29.4 NA NA NA
ALA D:120 D:118 83.0 0.722 H -63.3 -25.6 NA NA NA
4unk 1 P60174 99.6 0.0 X-RAY
 2015-02-04 ALA A:120 A:118 77.0 0.67 H -62.0 -39.6 77.0 0.67 0.0 HOH
 2.694
 O
 O
ALA B:120 B:118 77.0 0.67 H -63.2 -35.1 77.0 0.67 0.0 HOH
 3.086
 O
 O
4unl 1 P60174 99.6 0.0 X-RAY
 2015-02-04 ALA A:118 A:118 84.0 0.73 H -60.7 -33.4 84.0 0.73 0.0 HOH
 2.801
 O
 O
ALA B:118 B:118 73.0 0.635 H -66.9 -26.9 73.0 0.635 0.0 HOH
 3.852
 CB
 O
4br1 1 P60174 100.0 0.0 X-RAY
 2013-06-12 ALA A:116 A:118 82.0 0.713 H -59.7 -32.1 82.0 0.713 0.0 HOH
 3.503
 N
 O
ALA B:116 B:118 83.0 0.722 H -64.4 -36.0 83.0 0.722 0.0 HOH
 3.568
 N
 O
6d43 1 P60174 100.0 0.0 X-RAY
 2018-05-16 ALA A:116 A:118 78.0 0.678 H -58.2 -36.3 78.0 0.678 0.0 HOH
 2.947
 O
 O
6d43 2 P60174 100.0 0.0 X-RAY
 2018-05-16 ALA B:116 B:118 82.0 0.713 H -63.2 -33.5 82.0 0.713 0.0 HOH
 3.898
 CB
 O
1r2r 1 P00939 98.39 0.0 X-RAY
 2003-12-23 SER A:118 A:118 82.0 0.713 H -64.5 -25.4 82.0 0.713 0.0 HOH
 2.686
 OG
 O
SER B:118 B:118 87.0 0.757 H -64.3 -28.6 87.0 0.757 0.0 HOH
 2.647
 OG
 O
SER C:118 C:118 84.0 0.73 H -63.3 -23.5 NA NA NA
SER D:118 D:118 99.0 0.861 H -61.2 -34.8 NA NA NA
1r2s 1 P00939 98.39 0.0 X-RAY
 2003-12-23 SER A:118 A:118 98.0 0.852 H -56.6 -23.8 98.0 0.852 0.0 HOH
 5.091
 N
 O
SER B:118 B:118 99.0 0.861 H -53.8 -23.7 99.0 0.861 0.0 HOH
 7.321
 OG
 O
SER C:118 C:118 96.0 0.835 H -56.5 -24.9 NA NA NA
SER D:118 D:118 96.0 0.835 H -58.2 -22.3 NA NA NA
1r2t 1 P00939 98.39 0.0 X-RAY
 2003-12-23 SER A:118 A:118 85.0 0.739 H -68.2 -18.9 85.0 0.739 0.0 HOH
 2.620
 O
 O
SER B:118 B:118 86.0 0.748 H -65.7 -18.8 86.0 0.748 0.0 HOH
 2.757
 OG
 O
4owg 1 P00939 98.39 0.0 X-RAY
 2014-03-05 SER A:118 A:118 71.0 0.617 H -58.8 -33.0 71.0 0.617 0.0 HOH
 2.773
 O
 O
SER B:118 B:118 71.0 0.617 H -62.8 -31.6 71.0 0.617 0.0 HOH
 2.755
 O
 O
6nlh 1 P60174 99.59 0.0 X-RAY
 2019-06-19 ALA A:115 A:118 77.0 0.67 H -66.2 -29.3 77.0 0.67 0.0 HOH
 2.957
 HB2
 O
ALA B:115 E:118 83.0 0.722 H -61.1 -30.1 83.0 0.722 0.0 HOH
 2.703
 HB2
 O
ALA C:115 B:118 85.0 0.739 H -64.4 -29.0 NA NA NA
ALA D:115 C:118 82.0 0.713 H -63.7 -32.5 NA NA NA
ALA E:115 D:118 79.0 0.687 H -63.3 -27.4 NA NA NA
ALA F:115 F:118 84.0 0.73 H -63.6 -32.9 NA NA NA
ALA G:115 G:118 86.0 0.748 H -60.8 -27.7 NA NA NA
ALA H:115 H:118 83.0 0.722 H -66.5 -31.5 NA NA NA
1sw3 1 P00940 89.16 1e-162 X-RAY
 2004-08-24 ALA A:118 A:118 79.0 0.687 H -64.4 -31.9 79.0 0.687 0.0 HOH
 3.491
 CB
 O
ALA B:118 B:118 84.0 0.73 H -61.4 -36.2 84.0 0.73 0.0 HOH
 3.433
 N
 O
1tph 1 P00940 89.39 7e-162 X-RAY
 1994-04-30 ALA A:117 1:118 80.0 0.696 H -60.9 -38.9 80.0 0.696 0.0 HOH
 3.529
 CB
 O
ALA B:117 2:118 82.0 0.713 H -57.1 -33.9 82.0 0.713 0.0 HOH
 3.432
 N
 O
8tim 1 P00940 89.39 7e-162 X-RAY
 1999-02-16 ALA A:117 A:118 86.0 0.748 H -51.7 -36.6 86.0 0.748 0.0 HOH
 9.859
 C
 O
ALA B:117 B:118 75.0 0.652 H -52.2 -22.3 75.0 0.652 0.0 HOH
 3.297
 O
 O
1sw7 1 P00940 88.35 8e-162 X-RAY
 2004-08-24 ALA A:118 A:118 81.0 0.704 H -66.5 -28.5 81.0 0.704 0.0 HOH
 3.036
 O
 O
ALA B:118 B:118 73.0 0.635 H -66.9 -26.0 73.0 0.635 0.0 HOH
 4.732
 N
 O
1spq 1 P00940 89.39 1e-161 X-RAY
 2004-08-24 ALA A:117 A:118 83.0 0.722 H -64.1 -32.5 83.0 0.722 0.0 HOH
 3.160
 O
 O
ALA B:117 B:118 87.0 0.757 H -64.5 -29.6 87.0 0.757 0.0 HOH
 3.424
 CA
 O
1tpb 1 P00940 88.98 2e-161 X-RAY
 1995-02-14 ALA A:117 1:118 82.0 0.713 H -61.1 -32.7 82.0 0.713 0.0 HOH
 3.758
 CB
 O
ALA B:117 2:118 81.0 0.704 H -61.0 -32.4 81.0 0.704 0.0 HOH
 2.879
 O
 O
1sw0 1 P00940 88.76 6e-161 X-RAY
 2004-08-24 ALA A:118 A:118 81.0 0.704 H -67.3 -32.4 81.0 0.704 0.0 HOH
 3.690
 CB
 O
ALA B:118 B:118 79.0 0.687 H -60.3 -32.6 79.0 0.687 0.0 HOH
 3.332
 CB
 O
1tpw 1 P00940 88.98 8e-161 X-RAY
 1995-04-20 ALA A:117 A:118 80.0 0.696 H -56.8 -36.9 80.0 0.696 0.0 HOH
 3.055
 CB
 O
ALA B:117 B:118 86.0 0.748 H -62.8 -35.9 86.0 0.748 0.0 HOH
 3.621
 CB
 O
1tpu 1 P00940 88.98 1e-160 X-RAY
 1995-04-20 ALA A:117 A:118 78.0 0.678 H -66.5 -30.1 78.0 0.678 0.0 HOH
 3.661
 CB
 O
ALA B:117 B:118 81.0 0.704 H -59.9 -36.8 81.0 0.704 0.0 HOH
 7.471
 CB
 O
4p61 1 P00940 88.76 2e-160 X-RAY
 2014-08-27 ALA A:118 A:118 81.0 0.704 H -60.2 -33.6 81.0 0.704 0.0 HOH
 2.746
 O
 O
ALA B:118 B:118 83.0 0.722 H -62.0 -31.1 83.0 0.722 0.0 HOH
 3.400
 CA
 O
1tpc 1 P00940 88.57 2e-160 X-RAY
 1995-02-14 ALA A:117 1:118 81.0 0.704 H -59.3 -37.9 81.0 0.704 0.0 HOH
 3.430
 CB
 O
ALA B:117 2:118 82.0 0.713 H -57.4 -31.5 82.0 0.713 0.0 HOH
 3.446
 N
 O
1ssd 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 ALA A:117 A:118 79.0 0.687 H -62.4 -36.5 79.0 0.687 0.0 HOH
 3.672
 CB
 O
ALA B:117 B:118 81.0 0.704 H -66.2 -22.0 81.0 0.704 0.0 HOH
 4.972
 N
 O
1ssg 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 ALA A:117 A:118 82.0 0.713 H -65.9 -30.6 82.0 0.713 0.0 HOH
 4.748
 N
 O
ALA B:117 B:118 84.0 0.73 H -64.3 -32.3 84.0 0.73 0.0 GOL
HOH
 3.542
4.773
 CB
N
 O1
O
1sq7 1 P00940 88.98 4e-160 X-RAY
 2004-08-24 ALA A:117 A:118 84.0 0.73 H -66.9 -31.8 84.0 0.73 0.0 HOH
 3.443
 CB
 O
ALA B:117 B:118 86.0 0.748 H -64.4 -29.1 86.0 0.748 0.0 HOH
 4.642
 N
 O
1tpv 1 P00940 88.57 1e-159 X-RAY
 1995-04-20 ALA A:117 A:118 80.0 0.696 H -60.7 -32.0 80.0 0.696 0.0 HOH
 3.352
 CB
 O
ALA B:117 B:118 84.0 0.73 H -53.3 -40.6 84.0 0.73 0.0 HOH
 3.546
 CB
 O
1su5 1 P00940 88.57 1e-159 X-RAY
 2004-08-24 ALA A:117 A:118 81.0 0.704 H -69.2 -24.9 81.0 0.704 0.0 SO4
HOH
 3.370
3.438
 CB
CA
 O3
O
ALA B:117 B:118 78.0 0.678 H -64.9 -28.0 78.0 0.678 0.0 SO4
HOH
 3.058
3.441
 CB
CB
 O4
O
1tim 1 P00940 86.53 5e-158 X-RAY
 1976-10-15 ALA A:117 A:118 89.0 0.774 H -44.8 -42.2 89.0 0.774 0.0
ALA B:117 B:118 65.0 0.565 H -48.7 -68.6 65.0 0.565 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60174-f1 1 P60174 100.0 0.0 ALA A:119 A:119 85.0 0.739 H -61.8 -34.3