Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6978533 . G A CCDS53740.1:NM_001159287.1:c.547Gag>Aag_NP_001152759.1:p.183E>K Homo sapiens triosephosphate isomerase 1 (TPI1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6up1 1 P60174 100.0 0.0 X-RAY
 2020-07-01 GLU A:149 A:145 86.0 0.453 H -66.5 -41.9 86.0 0.453 0.0 HOH
 2.299
 O
 O
GLU B:149 B:145 79.0 0.416 H -65.2 -39.7 79.0 0.416 0.0 HOH
 2.849
 OE2
 O
6up5 1 P60174 100.0 0.0 X-RAY
 2020-07-01 GLU A:149 A:145 92.0 0.484 H -65.5 -45.4 92.0 0.484 0.0 HOH
 2.936
 OE1
 O
GLU B:149 B:145 79.0 0.416 H -58.2 -41.5 79.0 0.416 0.0 HOH
 2.703
 OE2
 O
4poc 1 P60174 100.0 0.0 X-RAY
 2015-01-14 GLU A:151 A:145 97.0 0.511 H -67.0 -42.9 97.0 0.511 0.0 HOH
 2.494
 HB3
 O
GLU B:151 B:145 86.0 0.453 H -64.5 -45.4 86.0 0.453 0.0 HOH
 2.709
 OE2
 O
6c2g 1 P60174 99.6 0.0 X-RAY
 2018-03-21 GLU A:146 A:145 94.0 0.495 H -63.1 -40.3 94.0 0.495 0.0 HOH
 5.077
 O
 O
GLU B:146 B:145 97.0 0.511 H -63.9 -39.3 NA NA NA
GLU C:146 C:145 98.0 0.516 H -64.0 -39.2 NA NA NA
GLU D:146 D:145 99.0 0.521 H -63.2 -40.0 NA NA NA
4pod 1 P60174 99.6 0.0 X-RAY
 2015-01-14 GLU A:151 A:145 88.0 0.463 H -67.7 -47.9 88.0 0.463 0.0 HOH
 2.379
 OE2
 O
GLU B:151 B:145 92.0 0.484 H -70.1 -40.5 92.0 0.484 0.0 HOH
 2.866
 HB2
 O
1wyi 1 P60174 100.0 0.0 X-RAY
 2005-04-12 GLU A:147 A:145 89.0 0.468 H -61.7 -42.3 72.0 0.379 0.089 B:P60174:0.089
 HOH
 2.508
 OE1
 O
GLU B:147 B:145 106.0 0.558 H -59.5 -39.3 87.0 0.458 0.1 B:P60174:0.1
 HOH
 3.030
 N
 O
2jk2 1 P60174 100.0 0.0 X-RAY
 2008-07-01 GLU A:147 A:145 96.0 0.505 H -64.1 -44.6 96.0 0.505 0.0 HOH
 5.005
 O
 O
GLU B:147 B:145 106.0 0.558 H -59.2 -44.8 106.0 0.558 0.0 HOH
 2.932
 O
 O
6up8 1 P60174 99.6 0.0 X-RAY
 2020-07-01 GLU A:149 A:145 101.0 0.532 H -52.5 -48.9 101.0 0.532 0.0 HOH
 2.327
 OE2
 O
GLU B:149 B:145 103.0 0.542 H -58.5 -39.6 103.0 0.542 0.0 HOH
 2.878
 OE2
 O
6upf 1 P60174 99.6 0.0 X-RAY
 2020-07-01 GLU A:149 A:145 82.0 0.432 H -63.5 -42.3 82.0 0.432 0.0 HOH
 2.725
 OE1
 O
GLU B:149 B:145 92.0 0.484 H -67.9 -39.5 92.0 0.484 0.0 HOH
 2.729
 OE1
 O
1hti 1 P60174 100.0 0.0 X-RAY
 1995-01-26 GLU A:145 A:145 91.0 0.479 H -56.4 -51.8 91.0 0.479 0.0
GLU B:145 B:145 115.0 0.605 H -63.7 -53.4 115.0 0.605 0.0
4zvj 1 P60174 99.6 0.0 X-RAY
 2016-03-09 GLU A:151 A:145 96.0 0.505 H -69.3 -43.6 96.0 0.505 0.0 HOH
 3.911
 HB3
 O
GLU B:151 B:145 98.0 0.516 H -66.2 -40.5 98.0 0.516 0.0 HOH
 2.460
 OE2
 O
2vom 1 P60174 99.6 0.0 X-RAY
 2008-06-17 GLU A:147 A:145 97.0 0.511 H -64.8 -43.5 97.0 0.511 0.0 HOH
 2.795
 CG
 O
GLU B:147 B:145 98.0 0.516 H -61.9 -45.1 98.0 0.516 0.0 HOH
 2.769
 O
 O
GLU C:147 C:145 97.0 0.511 H -66.8 -45.4 NA NA NA
GLU D:147 D:145 104.0 0.547 H -63.8 -41.2 NA NA NA
4unk 1 P60174 99.6 0.0 X-RAY
 2015-02-04 GLU A:147 A:145 88.0 0.463 H -63.1 -42.2 88.0 0.463 0.0 HOH
 2.356
 OE1
 O
GLU B:147 B:145 99.0 0.521 H -62.8 -39.8 99.0 0.521 0.0 HOH
 2.593
 OE2
 O
4unl 1 P60174 99.6 0.0 X-RAY
 2015-02-04 GLU A:145 A:145 91.0 0.479 H -67.4 -41.1 91.0 0.479 0.0 HOH
 2.784
 OE1
 O
GLU B:145 B:145 93.0 0.489 H -65.5 -40.7 93.0 0.489 0.0 HOH
 3.084
 OE1
 O
4br1 1 P60174 100.0 0.0 X-RAY
 2013-06-12 GLU A:143 A:145 91.0 0.479 H -61.8 -48.2 91.0 0.479 0.0 HOH
 5.067
 O
 O
GLU B:143 B:145 95.0 0.5 H -63.9 -43.4 95.0 0.5 0.0 HOH
 3.047
 CG
 O
6d43 1 P60174 100.0 0.0 X-RAY
 2018-05-16 GLU A:143 A:145 98.0 0.516 H -64.4 -46.4 98.0 0.516 0.0 HOH
 3.297
 CG
 O
6d43 2 P60174 100.0 0.0 X-RAY
 2018-05-16 GLU B:143 B:145 94.0 0.495 H -61.6 -44.5 94.0 0.495 0.0 HOH
 2.792
 OE2
 O
1r2r 1 P00939 98.39 0.0 X-RAY
 2003-12-23 GLU A:145 A:145 106.0 0.558 H -69.9 -36.5 106.0 0.558 0.0 HOH
 2.637
 OE1
 O
GLU B:145 B:145 95.0 0.5 H -69.7 -42.4 95.0 0.5 0.0 MG
HOH
 6.922
2.610
 C
OE1
 MG
O
GLU C:145 C:145 101.0 0.532 H -63.8 -40.9 NA NA NA
GLU D:145 D:145 99.0 0.521 H -67.9 -43.3 NA NA NA
1r2s 1 P00939 98.39 0.0 X-RAY
 2003-12-23 GLU A:145 A:145 122.0 0.642 H -50.2 -35.0 122.0 0.642 0.0 HOH
 5.573
 O
 O
GLU B:145 B:145 122.0 0.642 H -62.6 -38.8 122.0 0.642 0.0 HOH
 3.630
 CB
 O
GLU C:145 C:145 123.0 0.647 H -53.0 -39.7 NA NA NA
GLU D:145 D:145 115.0 0.605 H -58.8 -40.2 NA NA NA
1r2t 1 P00939 98.39 0.0 X-RAY
 2003-12-23 GLU A:145 A:145 95.0 0.5 H -66.5 -37.1 95.0 0.5 0.0 HOH
 3.400
 CB
 O
GLU B:145 B:145 97.0 0.511 H -62.0 -40.7 97.0 0.511 0.0 HOH
 2.741
 OE2
 O
4owg 1 P00939 98.39 0.0 X-RAY
 2014-03-05 GLU A:145 A:145 114.0 0.6 H -64.6 -41.7 114.0 0.6 0.0 HOH
 3.319
 OE2
 O
GLU B:145 B:145 99.0 0.521 H -64.0 -42.2 99.0 0.521 0.0 HOH
 2.706
 O
 O
6nlh 1 P60174 99.59 0.0 X-RAY
 2019-06-19 GLU A:142 A:145 90.0 0.474 H -60.7 -47.9 90.0 0.474 0.0 NA
HOH
 5.168
3.938
 O
OE2
 NA
O
GLU B:142 E:145 78.0 0.411 H -69.0 -39.5 78.0 0.411 0.0 HOH
 5.250
 O
 O
GLU C:142 B:145 103.0 0.542 H -59.1 -50.5 NA NA NA
GLU D:142 C:145 69.0 0.363 H -60.3 -45.4 NA NA NA
GLU E:142 D:145 94.0 0.495 H -67.5 -42.6 NA NA NA
GLU F:142 F:145 84.0 0.442 H -68.2 -39.9 NA NA NA
GLU G:142 G:145 96.0 0.505 H -64.2 -44.7 NA NA NA
GLU H:142 H:145 80.0 0.421 H -61.4 -45.1 NA NA NA
1sw3 1 P00940 89.16 1e-162 X-RAY
 2004-08-24 GLU A:145 A:145 119.0 0.626 H -63.5 -42.2 119.0 0.626 0.0 HOH
 2.672
 O
 O
GLU B:145 B:145 111.0 0.584 H -64.7 -44.1 111.0 0.584 0.0 HOH
 2.882
 O
 O
1tph 1 P00940 89.39 7e-162 X-RAY
 1994-04-30 GLU A:144 1:145 117.0 0.616 H -64.0 -47.8 117.0 0.616 0.0 HOH
 2.673
 O
 O
GLU B:144 2:145 141.0 0.742 H -66.9 -42.1 141.0 0.742 0.0 HOH
 3.104
 O
 O
8tim 1 P00940 89.39 7e-162 X-RAY
 1999-02-16 GLU A:144 A:145 113.0 0.595 H -62.3 -48.3 113.0 0.595 0.0
GLU B:144 B:145 105.0 0.553 H -76.3 -27.2 105.0 0.553 0.0 HOH
 9.976
 OE2
 O
1sw7 1 P00940 88.35 8e-162 X-RAY
 2004-08-24 GLU A:145 A:145 117.0 0.616 H -57.9 -47.1 117.0 0.616 0.0 HOH
 2.628
 O
 O
GLU B:145 B:145 112.0 0.589 H -59.9 -44.4 112.0 0.589 0.0 HOH
 3.091
 OE2
 O
1spq 1 P00940 89.39 1e-161 X-RAY
 2004-08-24 GLU A:144 A:145 105.0 0.553 H -64.3 -45.2 105.0 0.553 0.0 HOH
 2.756
 O
 O
GLU B:144 B:145 98.0 0.516 H -62.0 -47.3 98.0 0.516 0.0 HOH
 2.748
 O
 O
1tpb 1 P00940 88.98 2e-161 X-RAY
 1995-02-14 GLU A:144 1:145 125.0 0.658 H -70.4 -41.7 125.0 0.658 0.0 HOH
 3.066
 CG
 O
GLU B:144 2:145 133.0 0.7 H -68.9 -42.6 133.0 0.7 0.0 HOH
 3.050
 O
 O
1sw0 1 P00940 88.76 6e-161 X-RAY
 2004-08-24 GLU A:145 A:145 119.0 0.626 H -58.6 -51.3 119.0 0.626 0.0 HOH
 2.834
 O
 O
GLU B:145 B:145 114.0 0.6 H -79.8 -42.6 114.0 0.6 0.0 HOH
 2.996
 O
 O
1tpw 1 P00940 88.98 8e-161 X-RAY
 1995-04-20 GLU A:144 A:145 104.0 0.547 H -62.0 -52.4 104.0 0.547 0.0 HOH
 3.714
 N
 O
GLU B:144 B:145 104.0 0.547 H -54.8 -45.6 104.0 0.547 0.0 HOH
 3.214
 CB
 O
1tpu 1 P00940 88.98 1e-160 X-RAY
 1995-04-20 GLU A:144 A:145 93.0 0.489 H -73.9 -33.3 93.0 0.489 0.0 HOH
 3.247
 CG
 O
GLU B:144 B:145 135.0 0.711 H -67.4 -47.3 135.0 0.711 0.0 HOH
 2.879
 OE2
 O
4p61 1 P00940 88.76 2e-160 X-RAY
 2014-08-27 GLU A:145 A:145 117.0 0.616 H -60.0 -46.3 117.0 0.616 0.0 HOH
 2.751
 O
 O
GLU B:145 B:145 100.0 0.526 H -62.4 -45.3 100.0 0.526 0.0 HOH
 2.820
 O
 O
1tpc 1 P00940 88.57 2e-160 X-RAY
 1995-02-14 GLU A:144 1:145 116.0 0.611 H -65.8 -44.1 116.0 0.611 0.0 HOH
 3.836
 OE1
 O
GLU B:144 2:145 102.0 0.537 H -68.1 -47.4 102.0 0.537 0.0 HOH
 2.719
 OE1
 O
1ssd 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 GLU A:144 A:145 106.0 0.558 H -64.5 -44.7 106.0 0.558 0.0 HOH
 5.092
 O
 O
GLU B:144 B:145 113.0 0.595 H -56.0 -38.9 113.0 0.595 0.0 HOH
 5.179
 O
 O
1ssg 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 GLU A:144 A:145 112.0 0.589 H -49.0 -48.9 112.0 0.589 0.0 HOH
 5.269
 O
 O
GLU B:144 B:145 115.0 0.605 H -54.1 -51.2 115.0 0.605 0.0 SO4
HOH
 9.837
7.129
 OE2
OE2
 O4
O
1sq7 1 P00940 88.98 4e-160 X-RAY
 2004-08-24 GLU A:144 A:145 108.0 0.568 H -73.4 -44.7 108.0 0.568 0.0 HOH
 2.857
 O
 O
GLU B:144 B:145 118.0 0.621 H -60.8 -44.1 118.0 0.621 0.0 HOH
 4.825
 N
 O
1tpv 1 P00940 88.57 1e-159 X-RAY
 1995-04-20 GLU A:144 A:145 100.0 0.526 H -68.1 -47.7 100.0 0.526 0.0 HOH
 3.060
 OE2
 O
GLU B:144 B:145 79.0 0.416 H -58.3 -54.4 79.0 0.416 0.0 HOH
 3.525
 N
 O
1su5 1 P00940 88.57 1e-159 X-RAY
 2004-08-24 GLU A:144 A:145 113.0 0.595 H -58.0 -44.8 113.0 0.595 0.0 SO4
HOH
 9.950
2.986
 OE2
OE2
 O4
O
GLU B:144 B:145 107.0 0.563 H -55.8 -46.7 107.0 0.563 0.0 HOH
 2.596
 O
 O
1tim 1 P00940 86.53 5e-158 X-RAY
 1976-10-15 GLN A:144 A:145 116.0 0.644 H -52.0 -64.4 116.0 0.644 0.0
GLN B:144 B:145 99.0 0.55 H -52.7 -48.2 99.0 0.55 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60174-f1 1 P60174 100.0 0.0 GLU A:146 A:146 103.0 0.542 H -62.6 -48.2