Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6978545 . G A CCDS53740.1:NM_001159287.1:c.559Gtc>Atc_NP_001152759.1:p.187V>I Homo sapiens triosephosphate isomerase 1 (TPI1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6up1 1 P60174 100.0 0.0 X-RAY
 2020-07-01 VAL A:153 A:149 15.0 0.097 H -61.5 -41.7 15.0 0.097 0.0 HOH
 3.107
 CG2
 O
VAL B:153 B:149 25.0 0.161 H -64.3 -43.9 25.0 0.161 0.0 HOH
 3.637
 CG2
 O
6up5 1 P60174 100.0 0.0 X-RAY
 2020-07-01 VAL A:153 A:149 22.0 0.142 H -55.3 -47.0 22.0 0.142 0.0 HOH
 4.001
 CG1
 O
VAL B:153 B:149 26.0 0.168 H -63.2 -44.4 26.0 0.168 0.0 HOH
 3.865
 CB
 O
4poc 1 P60174 100.0 0.0 X-RAY
 2015-01-14 VAL A:155 A:149 23.0 0.148 H -63.1 -43.2 23.0 0.148 0.0 HOH
 3.078
 HB
 O
VAL B:155 B:149 24.0 0.155 H -62.7 -41.8 24.0 0.155 0.0 HOH
 3.190
 HB
 O
6c2g 1 P60174 99.6 0.0 X-RAY
 2018-03-21 VAL A:150 A:149 37.0 0.239 H -63.9 -39.6 37.0 0.239 0.0 HOH
 4.029
 CB
 O
VAL B:150 B:149 37.0 0.239 H -63.2 -39.9 NA NA NA
VAL C:150 C:149 23.0 0.148 H -63.2 -40.0 NA NA NA
VAL D:150 D:149 38.0 0.245 H -63.2 -40.3 NA NA NA
4pod 1 P60174 99.6 0.0 X-RAY
 2015-01-14 VAL A:155 A:149 16.0 0.103 H -60.4 -40.6 16.0 0.103 0.0 HOH
 3.104
 HG22
 O
VAL B:155 B:149 21.0 0.135 H -65.8 -40.8 21.0 0.135 0.0 HOH
 3.062
 HB
 O
1wyi 1 P60174 100.0 0.0 X-RAY
 2005-04-12 VAL A:151 A:149 32.0 0.206 H -59.7 -34.6 32.0 0.206 0.0 HOH
 3.461
 CG2
 O
VAL B:151 B:149 37.0 0.239 H -57.8 -35.8 37.0 0.239 0.0 HOH
 3.390
 CG2
 O
2jk2 1 P60174 100.0 0.0 X-RAY
 2008-07-01 VAL A:151 A:149 28.0 0.181 H -66.7 -32.4 28.0 0.181 0.0 HOH
 4.155
 CB
 O
VAL B:151 B:149 39.0 0.252 H -62.9 -41.0 39.0 0.252 0.0 HOH
 3.593
 CG2
 O
6up8 1 P60174 99.6 0.0 X-RAY
 2020-07-01 VAL A:153 A:149 22.0 0.142 H -60.9 -41.3 22.0 0.142 0.0 IPA
HOH
 9.163
3.885
 O
CG2
 O2
O
VAL B:153 B:149 24.0 0.155 H -60.9 -42.8 24.0 0.155 0.0 HOH
 4.105
 CG2
 O
6upf 1 P60174 99.6 0.0 X-RAY
 2020-07-01 VAL A:153 A:149 26.0 0.168 H -68.0 -39.7 26.0 0.168 0.0 HOH
 3.631
 CG2
 O
VAL B:153 B:149 22.0 0.142 H -65.4 -41.7 22.0 0.142 0.0 HOH
 3.720
 CG2
 O
1hti 1 P60174 100.0 0.0 X-RAY
 1995-01-26 VAL A:149 A:149 15.0 0.097 H -70.1 -22.8 15.0 0.097 0.0
VAL B:149 B:149 41.0 0.265 H -56.7 -52.8 41.0 0.265 0.0
4zvj 1 P60174 99.6 0.0 X-RAY
 2016-03-09 VAL A:155 A:149 13.0 0.084 H -68.6 -38.3 13.0 0.084 0.0 HOH
 3.173
 HB
 O
VAL B:155 B:149 24.0 0.155 H -62.6 -40.5 24.0 0.155 0.0 HOH
 3.172
 HG21
 O
2vom 1 P60174 99.6 0.0 X-RAY
 2008-06-17 VAL A:151 A:149 34.0 0.219 H -58.4 -42.1 34.0 0.219 0.0 HOH
 3.225
 CG2
 O
VAL B:151 B:149 35.0 0.226 H -58.9 -42.3 35.0 0.226 0.0 HOH
 3.664
 CG2
 O
VAL C:151 C:149 35.0 0.226 H -58.7 -41.2 NA NA NA
VAL D:151 D:149 34.0 0.219 H -53.8 -42.9 NA NA NA
4unk 1 P60174 99.6 0.0 X-RAY
 2015-02-04 VAL A:151 A:149 22.0 0.142 H -61.6 -44.5 22.0 0.142 0.0 HOH
 3.649
 CG2
 O
VAL B:151 B:149 30.0 0.194 H -63.9 -40.2 30.0 0.194 0.0 HOH
 3.574
 CG2
 O
4unl 1 P60174 99.6 0.0 X-RAY
 2015-02-04 VAL A:149 A:149 24.0 0.155 H -63.0 -44.0 24.0 0.155 0.0 HOH
 4.101
 CB
 O
VAL B:149 B:149 12.0 0.077 H -65.3 -37.4 12.0 0.077 0.0 HOH
 4.147
 CB
 O
4br1 1 P60174 100.0 0.0 X-RAY
 2013-06-12 VAL A:147 A:149 35.0 0.226 H -63.4 -42.0 35.0 0.226 0.0 HOH
 3.861
 CB
 O
VAL B:147 B:149 33.0 0.213 H -62.9 -43.4 33.0 0.213 0.0 HOH
 3.470
 CG2
 O
6d43 1 P60174 100.0 0.0 X-RAY
 2018-05-16 VAL A:147 A:149 20.0 0.129 H -60.0 -41.9 20.0 0.129 0.0 HOH
 3.866
 CB
 O
6d43 2 P60174 100.0 0.0 X-RAY
 2018-05-16 VAL B:147 B:149 23.0 0.148 H -65.3 -42.0 23.0 0.148 0.0 HOH
 4.027
 CG1
 O
1r2r 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:149 A:149 35.0 0.226 H -65.4 -42.2 35.0 0.226 0.0 HOH
 3.413
 CG2
 O
VAL B:149 B:149 22.0 0.142 H -67.4 -38.8 22.0 0.142 0.0 MG
HOH
 8.031
3.141
 CG2
CG1
 MG
O
VAL C:149 C:149 26.0 0.168 H -63.5 -44.3 NA NA NA
VAL D:149 D:149 20.0 0.129 H -64.3 -42.4 NA NA NA
1r2s 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:149 A:149 40.0 0.258 H -56.2 -45.1 40.0 0.258 0.0 HOH
 4.349
 CB
 O
VAL B:149 B:149 37.0 0.239 H -56.8 -38.7 37.0 0.239 0.0 HOH
 4.194
 CB
 O
VAL C:149 C:149 38.0 0.245 H -56.1 -39.9 NA NA NA
VAL D:149 D:149 39.0 0.252 H -61.5 -36.6 NA NA NA
1r2t 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:149 A:149 12.0 0.077 H -63.6 -38.4 12.0 0.077 0.0 HOH
 4.116
 CB
 O
VAL B:149 B:149 21.0 0.135 H -63.7 -38.8 21.0 0.135 0.0 HOH
 3.744
 CG2
 O
4owg 1 P00939 98.39 0.0 X-RAY
 2014-03-05 VAL A:149 A:149 37.0 0.239 H -62.6 -43.9 37.0 0.239 0.0 HOH
 3.976
 CB
 O
VAL B:149 B:149 40.0 0.258 H -62.4 -44.3 40.0 0.258 0.0 HOH
 3.517
 CG2
 O
6nlh 1 P60174 99.59 0.0 X-RAY
 2019-06-19 VAL A:146 A:149 12.0 0.077 H -62.0 -38.8 12.0 0.077 0.0 NA
HOH
 3.097
4.991
 HB
HG22
 NA
O
VAL B:146 E:149 20.0 0.129 H -66.4 -42.8 20.0 0.129 0.0 HOH
 3.308
 HB
 O
VAL C:146 B:149 15.0 0.097 H -67.6 -35.6 NA NA NA
VAL D:146 C:149 23.0 0.148 H -66.1 -33.9 NA NA NA
VAL E:146 D:149 14.0 0.09 H -67.1 -35.9 NA NA NA
VAL F:146 F:149 22.0 0.142 H -62.6 -42.0 NA NA NA
VAL G:146 G:149 18.0 0.116 H -71.1 -35.2 NA NA NA
VAL H:146 H:149 21.0 0.135 H -68.3 -36.2 NA NA NA
1sw3 1 P00940 89.16 1e-162 X-RAY
 2004-08-24 ALA A:149 A:149 24.0 0.209 H -60.1 -34.2 24.0 0.209 0.0 HOH
 2.951
 CB
 O
ALA B:149 B:149 22.0 0.191 H -56.5 -35.5 22.0 0.191 0.0 HOH
 3.853
 CB
 O
1tph 1 P00940 89.39 7e-162 X-RAY
 1994-04-30 ALA A:148 1:149 27.0 0.235 H -58.4 -35.6 27.0 0.235 0.0 HOH
 3.577
 O
 O
ALA B:148 2:149 21.0 0.183 H -58.6 -36.9 21.0 0.183 0.0 HOH
 3.619
 CB
 O
8tim 1 P00940 89.39 7e-162 X-RAY
 1999-02-16 ALA A:148 A:149 22.0 0.191 H -49.6 -41.7 22.0 0.191 0.0
ALA B:148 B:149 21.0 0.183 H -63.0 -34.5 21.0 0.183 0.0
1sw7 1 P00940 88.35 8e-162 X-RAY
 2004-08-24 ALA A:149 A:149 20.0 0.174 H -63.7 -28.1 20.0 0.174 0.0 HOH
 3.694
 N
 O
ALA B:149 B:149 20.0 0.174 H -66.7 -32.2 20.0 0.174 0.0 HOH
 3.577
 CA
 O
1spq 1 P00940 89.39 1e-161 X-RAY
 2004-08-24 ALA A:148 A:149 14.0 0.122 H -65.7 -25.1 14.0 0.122 0.0 HOH
 3.870
 CB
 O
ALA B:148 B:149 26.0 0.226 H -69.0 -26.7 26.0 0.226 0.0 HOH
 3.728
 CB
 O
1tpb 1 P00940 88.98 2e-161 X-RAY
 1995-02-14 ALA A:148 1:149 25.0 0.217 H -61.1 -32.8 25.0 0.217 0.0 HOH
 3.515
 O
 O
ALA B:148 2:149 20.0 0.174 H -54.1 -34.3 20.0 0.174 0.0 HOH
 3.657
 CB
 O
1sw0 1 P00940 88.76 6e-161 X-RAY
 2004-08-24 ALA A:149 A:149 25.0 0.217 H -60.5 -37.2 25.0 0.217 0.0 HOH
 3.763
 N
 O
ALA B:149 B:149 23.0 0.2 H -60.8 -45.2 23.0 0.2 0.0 HOH
 3.779
 CB
 O
1tpw 1 P00940 88.98 8e-161 X-RAY
 1995-04-20 ALA A:148 A:149 24.0 0.209 H -61.7 -27.4 24.0 0.209 0.0 HOH
 3.578
 CB
 O
ALA B:148 B:149 20.0 0.174 H -60.2 -31.7 20.0 0.174 0.0 HOH
 3.325
 O
 O
1tpu 1 P00940 88.98 1e-160 X-RAY
 1995-04-20 ALA A:148 A:149 24.0 0.209 H -59.7 -37.8 24.0 0.209 0.0 HOH
 3.801
 CA
 O
ALA B:148 B:149 20.0 0.174 H -59.2 -43.4 20.0 0.174 0.0 HOH
 3.589
 CB
 O
4p61 1 P00940 88.76 2e-160 X-RAY
 2014-08-27 ALA A:149 A:149 18.0 0.157 H -62.2 -34.2 18.0 0.157 0.0 HOH
 3.051
 O
 O
ALA B:149 B:149 22.0 0.191 H -61.4 -33.6 22.0 0.191 0.0 HOH
 3.053
 O
 O
1tpc 1 P00940 88.57 2e-160 X-RAY
 1995-02-14 ALA A:148 1:149 25.0 0.217 H -57.8 -34.3 25.0 0.217 0.0 HOH
 3.835
 CB
 O
ALA B:148 2:149 19.0 0.165 H -62.2 -35.1 19.0 0.165 0.0 HOH
 3.778
 N
 O
1ssd 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 ALA A:148 A:149 19.0 0.165 H -65.3 -29.5 19.0 0.165 0.0 HOH
 3.625
 CB
 O
ALA B:148 B:149 15.0 0.13 H -66.2 -33.0 15.0 0.13 0.0 HOH
 3.847
 CB
 O
1ssg 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 ALA A:148 A:149 19.0 0.165 H -57.1 -34.3 19.0 0.165 0.0 HOH
 3.600
 CB
 O
ALA B:148 B:149 21.0 0.183 H -63.5 -37.0 21.0 0.183 0.0 HOH
 7.238
 CB
 O
1sq7 1 P00940 88.98 4e-160 X-RAY
 2004-08-24 ALA A:148 A:149 21.0 0.183 H -62.7 -28.5 21.0 0.183 0.0 HOH
 3.683
 CB
 O
ALA B:148 B:149 19.0 0.165 H -66.7 -27.6 19.0 0.165 0.0 HOH
 4.890
 O
 O
1tpv 1 P00940 88.57 1e-159 X-RAY
 1995-04-20 ALA A:148 A:149 25.0 0.217 H -68.0 -28.5 25.0 0.217 0.0 HOH
 3.914
 CB
 O
ALA B:148 B:149 18.0 0.157 H -59.9 -42.9 18.0 0.157 0.0 HOH
 3.537
 CB
 O
1su5 1 P00940 88.57 1e-159 X-RAY
 2004-08-24 ALA A:148 A:149 22.0 0.191 H -67.3 -35.1 22.0 0.191 0.0 HOH
 4.814
 O
 O
ALA B:148 B:149 18.0 0.157 H -68.2 -33.1 18.0 0.157 0.0 HOH
 3.529
 CB
 O
1tim 1 P00940 86.53 5e-158 X-RAY
 1976-10-15 ALA A:148 A:149 16.0 0.139 H -39.1 -63.8 16.0 0.139 0.0
ALA B:148 B:149 17.0 0.148 H -45.0 -63.9 17.0 0.148 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60174-f1 1 P60174 100.0 0.0 VAL A:150 A:150 41.0 0.265 H -64.5 -35.8