Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6978857 . G A CCDS53740.1:NM_001159287.1:c.574Gtg>Atg_NP_001152759.1:p.192V>M Homo sapiens triosephosphate isomerase 1 (TPI1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6up1 1 P60174 100.0 0.0 X-RAY
 2020-07-01 VAL A:158 A:154 10.0 0.065 -117.4 122.1 10.0 0.065 0.0 HOH
 2.740
 O
 O
VAL B:158 B:154 17.0 0.11 -114.1 130.7 17.0 0.11 0.0 HOH
 3.347
 O
 O
6up5 1 P60174 100.0 0.0 X-RAY
 2020-07-01 VAL A:158 A:154 11.0 0.071 -119.5 122.6 11.0 0.071 0.0 HOH
 3.053
 O
 O
VAL B:158 B:154 18.0 0.116 -118.8 120.9 18.0 0.116 0.0 HOH
 3.105
 O
 O
4poc 1 P60174 100.0 0.0 X-RAY
 2015-01-14 VAL A:160 A:154 15.0 0.097 -120.9 126.0 15.0 0.097 0.0 HOH
 2.785
 O
 O
VAL B:160 B:154 14.0 0.09 -118.1 123.0 14.0 0.09 0.0 HOH
 2.791
 O
 O
6c2g 1 P60174 99.6 0.0 X-RAY
 2018-03-21 VAL A:155 A:154 14.0 0.09 -117.4 117.5 14.0 0.09 0.0 HOH
 2.661
 O
 O
VAL B:155 B:154 15.0 0.097 -117.9 118.8 NA NA NA
VAL C:155 C:154 14.0 0.09 -117.0 119.5 NA NA NA
VAL D:155 D:154 14.0 0.09 -117.4 118.2 NA NA NA
4pod 1 P60174 99.6 0.0 X-RAY
 2015-01-14 VAL A:160 A:154 14.0 0.09 -122.9 124.2 14.0 0.09 0.0 HOH
 2.601
 HA
 O
VAL B:160 B:154 15.0 0.097 -113.9 118.8 15.0 0.097 0.0 HOH
 3.141
 O
 O
1wyi 1 P60174 100.0 0.0 X-RAY
 2005-04-12 VAL A:156 A:154 12.0 0.077 -123.1 113.2 12.0 0.077 0.0 HOH
 3.262
 CA
 O
VAL B:156 B:154 9.0 0.058 -110.6 130.6 9.0 0.058 0.0 HOH
 2.523
 O
 O
2jk2 1 P60174 100.0 0.0 X-RAY
 2008-07-01 VAL A:156 A:154 11.0 0.071 -118.2 122.1 11.0 0.071 0.0 HOH
 3.552
 CA
 O
VAL B:156 B:154 16.0 0.103 -110.8 131.2 16.0 0.103 0.0 HOH
 3.096
 O
 O
6up8 1 P60174 99.6 0.0 X-RAY
 2020-07-01 VAL A:158 A:154 10.0 0.065 -119.3 128.7 10.0 0.065 0.0 IPA
HOH
 3.648
2.591
 CA
O
 O2
O
VAL B:158 B:154 18.0 0.116 -115.0 122.7 18.0 0.116 0.0 IPA
HOH
 8.839
3.117
 N
O
 O2
O
6upf 1 P60174 99.6 0.0 X-RAY
 2020-07-01 VAL A:158 A:154 14.0 0.09 -117.5 115.2 14.0 0.09 0.0 HOH
 2.966
 O
 O
VAL B:158 B:154 15.0 0.097 -121.1 121.7 15.0 0.097 0.0 HOH
 2.575
 O
 O
1hti 1 P60174 100.0 0.0 X-RAY
 1995-01-26 VAL A:154 A:154 13.0 0.084 -113.8 123.2 13.0 0.084 0.0
VAL B:154 B:154 12.0 0.077 -92.6 136.2 12.0 0.077 0.0
4zvj 1 P60174 99.6 0.0 X-RAY
 2016-03-09 VAL A:160 A:154 9.0 0.058 -116.4 131.9 9.0 0.058 0.0 HOH
 2.802
 HA
 O
VAL B:160 B:154 16.0 0.103 -112.6 125.1 16.0 0.103 0.0 HOH
 2.989
 HA
 O
2vom 1 P60174 99.6 0.0 X-RAY
 2008-06-17 VAL A:156 A:154 14.0 0.09 -116.5 122.2 14.0 0.09 0.0 HOH
 2.728
 O
 O
VAL B:156 B:154 14.0 0.09 -119.3 118.1 14.0 0.09 0.0 HOH
 3.051
 O
 O
VAL C:156 C:154 15.0 0.097 -121.1 127.5 NA NA NA
VAL D:156 D:154 16.0 0.103 -115.7 118.4 NA NA NA
4unk 1 P60174 99.6 0.0 X-RAY
 2015-02-04 VAL A:156 A:154 15.0 0.097 -117.9 123.9 15.0 0.097 0.0 HOH
 3.117
 O
 O
VAL B:156 B:154 13.0 0.084 -123.4 115.3 13.0 0.084 0.0 HOH
 2.897
 O
 O
4unl 1 P60174 99.6 0.0 X-RAY
 2015-02-04 VAL A:154 A:154 16.0 0.103 -111.8 128.6 16.0 0.103 0.0 HOH
 3.065
 O
 O
VAL B:154 B:154 10.0 0.065 -114.7 116.9 10.0 0.065 0.0 HOH
 2.871
 O
 O
4br1 1 P60174 100.0 0.0 X-RAY
 2013-06-12 VAL A:152 A:154 14.0 0.09 -123.3 114.6 14.0 0.09 0.0 HOH
 2.972
 O
 O
VAL B:152 B:154 16.0 0.103 -116.9 122.3 16.0 0.103 0.0 HOH
 2.746
 O
 O
6d43 1 P60174 100.0 0.0 X-RAY
 2018-05-16 VAL A:152 A:154 16.0 0.103 -122.4 124.7 16.0 0.103 0.0 HOH
 3.256
 O
 O
6d43 2 P60174 100.0 0.0 X-RAY
 2018-05-16 VAL B:152 B:154 16.0 0.103 -111.5 118.8 16.0 0.103 0.0 HOH
 3.231
 O
 O
1r2r 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:154 A:154 1.0 0.006 -123.6 120.1 1.0 0.006 0.0 HOH
 3.055
 O
 O
VAL B:154 B:154 16.0 0.103 -115.4 120.5 16.0 0.103 0.0 HOH
 2.890
 O
 O
VAL C:154 C:154 15.0 0.097 -118.4 121.6 NA NA NA
VAL D:154 D:154 13.0 0.084 -122.2 119.3 NA NA NA
1r2s 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:154 A:154 19.0 0.123 -102.0 130.6 19.0 0.123 0.0 HOH
 4.089
 O
 O
VAL B:154 B:154 17.0 0.11 -99.7 129.1 17.0 0.11 0.0 HOH
 4.241
 O
 O
VAL C:154 C:154 19.0 0.123 -98.2 131.0 NA NA NA
VAL D:154 D:154 18.0 0.116 -99.3 132.2 NA NA NA
1r2t 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:154 A:154 13.0 0.084 -116.1 125.4 13.0 0.084 0.0 HOH
 3.163
 O
 O
VAL B:154 B:154 15.0 0.097 -114.6 123.8 15.0 0.097 0.0 HOH
 3.306
 O
 O
4owg 1 P00939 98.39 0.0 X-RAY
 2014-03-05 VAL A:154 A:154 20.0 0.129 -80.5 115.7 20.0 0.129 0.0 HOH
 3.733
 O
 O
VAL B:154 B:154 19.0 0.123 -80.9 117.0 19.0 0.123 0.0 HOH
 3.405
 O
 O
6nlh 1 P60174 99.59 0.0 X-RAY
 2019-06-19 VAL A:151 A:154 15.0 0.097 -117.6 118.7 15.0 0.097 0.0 NA
HOH
 9.176
3.015
 HG23
O
 NA
O
VAL B:151 E:154 16.0 0.103 -117.7 130.1 16.0 0.103 0.0 HOH
 2.785
 HA
 O
VAL C:151 B:154 12.0 0.077 -120.3 110.2 NA NA NA
VAL D:151 C:154 18.0 0.116 -120.5 121.3 NA NA NA
VAL E:151 D:154 7.0 0.045 -121.7 110.3 NA NA NA
VAL F:151 F:154 15.0 0.097 -112.9 120.8 NA NA NA
VAL G:151 G:154 11.0 0.071 -118.4 116.9 NA NA NA
VAL H:151 H:154 16.0 0.103 -118.5 122.2 NA NA NA
1sw3 1 P00940 89.16 1e-162 X-RAY
 2004-08-24 VAL A:154 A:154 14.0 0.09 -114.3 116.8 14.0 0.09 0.0 HOH
 3.363
 O
 O
VAL B:154 B:154 13.0 0.084 -116.9 121.8 13.0 0.084 0.0 HOH
 3.402
 O
 O
1tph 1 P00940 89.39 7e-162 X-RAY
 1994-04-30 VAL A:153 1:154 14.0 0.09 -110.4 113.8 14.0 0.09 0.0 HOH
 3.387
 O
 O
VAL B:153 2:154 18.0 0.116 -109.6 124.9 18.0 0.116 0.0 HOH
 3.194
 O
 O
8tim 1 P00940 89.39 7e-162 X-RAY
 1999-02-16 VAL A:153 A:154 16.0 0.103 -83.0 149.0 16.0 0.103 0.0 HOH
 8.364
 CG1
 O
VAL B:153 B:154 15.0 0.097 -112.0 129.8 15.0 0.097 0.0 HOH
 5.456
 CA
 O
1sw7 1 P00940 88.35 8e-162 X-RAY
 2004-08-24 VAL A:154 A:154 13.0 0.084 -114.6 112.0 13.0 0.084 0.0 HOH
 5.993
 CA
 O
VAL B:154 B:154 15.0 0.097 -118.5 115.1 15.0 0.097 0.0 HOH
 4.217
 C
 O
1spq 1 P00940 89.39 1e-161 X-RAY
 2004-08-24 VAL A:153 A:154 17.0 0.11 -115.5 125.1 17.0 0.11 0.0 HOH
 3.018
 O
 O
VAL B:153 B:154 15.0 0.097 -113.7 112.3 15.0 0.097 0.0 HOH
 2.769
 O
 O
1tpb 1 P00940 88.98 2e-161 X-RAY
 1995-02-14 VAL A:153 1:154 15.0 0.097 -110.4 116.9 15.0 0.097 0.0 HOH
 2.735
 O
 O
VAL B:153 2:154 18.0 0.116 -113.9 122.4 18.0 0.116 0.0 HOH
 3.855
 C
 O
1sw0 1 P00940 88.76 6e-161 X-RAY
 2004-08-24 VAL A:154 A:154 14.0 0.09 -114.9 119.2 14.0 0.09 0.0 HOH
 2.807
 O
 O
VAL B:154 B:154 15.0 0.097 -120.3 122.7 15.0 0.097 0.0 HOH
 2.737
 O
 O
1tpw 1 P00940 88.98 8e-161 X-RAY
 1995-04-20 VAL A:153 A:154 15.0 0.097 -119.2 110.1 15.0 0.097 0.0 HOH
 3.289
 O
 O
VAL B:153 B:154 14.0 0.09 -107.2 119.9 14.0 0.09 0.0 HOH
 3.456
 O
 O
1tpu 1 P00940 88.98 1e-160 X-RAY
 1995-04-20 VAL A:153 A:154 16.0 0.103 -108.5 120.9 16.0 0.103 0.0 HOH
 3.478
 CA
 O
VAL B:153 B:154 15.0 0.097 -115.5 121.4 15.0 0.097 0.0 HOH
 3.534
 O
 O
4p61 1 P00940 88.76 2e-160 X-RAY
 2014-08-27 VAL A:154 A:154 15.0 0.097 -117.1 122.8 15.0 0.097 0.0 HOH
 3.006
 O
 O
VAL B:154 B:154 15.0 0.097 -117.3 115.2 15.0 0.097 0.0 HOH
 2.797
 O
 O
1tpc 1 P00940 88.57 2e-160 X-RAY
 1995-02-14 VAL A:153 1:154 15.0 0.097 -118.7 122.6 15.0 0.097 0.0 HOH
 2.990
 O
 O
VAL B:153 2:154 18.0 0.116 -112.9 129.8 18.0 0.116 0.0 HOH
 5.262
 CG1
 O
1ssd 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 VAL A:153 A:154 15.0 0.097 -99.4 117.4 15.0 0.097 0.0 HOH
 9.728
 CG1
 O
VAL B:153 B:154 14.0 0.09 -73.1 118.4 14.0 0.09 0.0 HOH
 5.877
 CG1
 O
1ssg 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 VAL A:153 A:154 14.0 0.09 -113.7 112.0 14.0 0.09 0.0 HOH
 5.790
 CG1
 O
VAL B:153 B:154 14.0 0.09 -117.1 114.6 14.0 0.09 0.0 GOL
HOH
 9.244
3.914
 N
C
 O3
O
1sq7 1 P00940 88.98 4e-160 X-RAY
 2004-08-24 VAL A:153 A:154 12.0 0.077 -116.0 119.5 12.0 0.077 0.0 HOH
 5.557
 CA
 O
VAL B:153 B:154 13.0 0.084 -115.2 111.6 13.0 0.084 0.0 HOH
 4.306
 C
 O
1tpv 1 P00940 88.57 1e-159 X-RAY
 1995-04-20 VAL A:153 A:154 15.0 0.097 -113.5 123.7 15.0 0.097 0.0 HOH
 2.921
 O
 O
VAL B:153 B:154 16.0 0.103 -113.0 127.1 16.0 0.103 0.0 HOH
 3.002
 O
 O
1su5 1 P00940 88.57 1e-159 X-RAY
 2004-08-24 VAL A:153 A:154 15.0 0.097 -114.4 109.7 15.0 0.097 0.0 SO4
HOH
 9.018
3.278
 N
O
 O1
O
VAL B:153 B:154 14.0 0.09 -121.2 109.2 14.0 0.09 0.0 SO4
HOH
 9.003
4.862
 N
C
 O1
O
1tim 1 P00940 86.53 5e-158 X-RAY
 1976-10-15 VAL A:153 A:154 13.0 0.084 -27.9 -172.7 13.0 0.084 0.0
VAL B:153 B:154 2.0 0.013 -60.1 178.9 2.0 0.013 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60174-f1 1 P60174 100.0 0.0 VAL A:155 A:155 13.0 0.084 -107.9 116.6