Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6978885 . C A CCDS53740.1:NM_001159287.1:c.602gCc>gAc_NP_001152759.1:p.201A>D Homo sapiens triosephosphate isomerase 1 (TPI1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6up1 1 P60174 100.0 0.0 X-RAY
 2020-07-01 ALA A:167 A:163 0.0 0.0 E -120.1 116.2 0.0 0.0 0.0 HOH
 5.667
 O
 O
ALA B:167 B:163 0.0 0.0 E -119.0 113.8 0.0 0.0 0.0 HOH
 5.718
 O
 O
6up5 1 P60174 100.0 0.0 X-RAY
 2020-07-01 ALA A:167 A:163 0.0 0.0 E -118.4 117.7 0.0 0.0 0.0 HOH
 5.552
 CB
 O
ALA B:167 B:163 0.0 0.0 E -115.7 111.9 0.0 0.0 0.0 PGA
HOH
 7.308
5.530
 CB
O
 O1
O
4poc 1 P60174 100.0 0.0 X-RAY
 2015-01-14 ALA A:169 A:163 0.0 0.0 E -117.7 118.1 0.0 0.0 0.0 HOH
 5.125
 HB1
 O
ALA B:169 B:163 0.0 0.0 E -113.7 112.3 0.0 0.0 0.0 PO4
BR
HOH
 9.571
7.180
5.079
 HB1
HB1
O
 O3
BR
O
6c2g 1 P60174 99.6 0.0 X-RAY
 2018-03-21 ALA A:164 A:163 0.0 0.0 E -122.2 115.1 0.0 0.0 0.0 HOH
 5.810
 O
 O
ALA B:164 B:163 0.0 0.0 E -121.9 115.2 NA NA NA
ALA C:164 C:163 0.0 0.0 E -121.0 115.4 NA NA NA
ALA D:164 D:163 0.0 0.0 E -121.9 115.4 NA NA NA
4pod 1 P60174 99.6 0.0 X-RAY
 2015-01-14 ALA A:169 A:163 0.0 0.0 E -116.0 116.5 0.0 0.0 0.0 HOH
 5.507
 O
 O
ALA B:169 B:163 0.0 0.0 E -112.9 105.6 0.0 0.0 0.0 PO4
BR
HOH
 9.430
7.161
5.411
 HB1
HB1
O
 O2
BR
O
1wyi 1 P60174 100.0 0.0 X-RAY
 2005-04-12 ALA A:165 A:163 0.0 0.0 E -123.3 115.8 0.0 0.0 0.0 HOH
 2.759
 N
 O
ALA B:165 B:163 0.0 0.0 E -135.1 105.4 0.0 0.0 0.0 HOH
 3.334
 C
 O
2jk2 1 P60174 100.0 0.0 X-RAY
 2008-07-01 ALA A:165 A:163 0.0 0.0 E -117.1 119.4 0.0 0.0 0.0 HOH
 5.530
 O
 O
ALA B:165 B:163 0.0 0.0 E -121.4 120.0 0.0 0.0 0.0 HOH
 4.010
 N
 O
6up8 1 P60174 99.6 0.0 X-RAY
 2020-07-01 ALA A:167 A:163 0.0 0.0 E -117.2 117.6 0.0 0.0 0.0 HOH
 5.542
 O
 O
ALA B:167 B:163 0.0 0.0 E -115.6 119.0 0.0 0.0 0.0 HOH
 5.657
 O
 O
6upf 1 P60174 99.6 0.0 X-RAY
 2020-07-01 ALA A:167 A:163 0.0 0.0 E -119.0 112.8 0.0 0.0 0.0 PGA
HOH
 7.303
5.032
 CB
O
 O2
O
ALA B:167 B:163 0.0 0.0 E -119.0 113.2 0.0 0.0 0.0 PGA
HOH
 7.160
5.191
 CB
O
 O2
O
1hti 1 P60174 100.0 0.0 X-RAY
 1995-01-26 ALA A:163 A:163 0.0 0.0 E -135.0 120.9 0.0 0.0 0.0
ALA B:163 B:163 0.0 0.0 E -126.9 114.8 0.0 0.0 0.0 PGA
 7.442
 CB
 O2
4zvj 1 P60174 99.6 0.0 X-RAY
 2016-03-09 ALA A:169 A:163 0.0 0.0 E -118.8 117.3 0.0 0.0 0.0 HOH
 5.492
 O
 O
ALA B:169 B:163 0.0 0.0 E -118.5 117.7 0.0 0.0 0.0 HOH
 5.523
 O
 O
2vom 1 P60174 99.6 0.0 X-RAY
 2008-06-17 ALA A:165 A:163 0.0 0.0 E -116.3 121.7 0.0 0.0 0.0 HOH
 5.475
 O
 O
ALA B:165 B:163 0.0 0.0 E -122.8 116.8 0.0 0.0 0.0 HOH
 5.544
 O
 O
ALA C:165 C:163 0.0 0.0 E -121.0 113.3 NA NA NA
ALA D:165 D:163 0.0 0.0 E -125.4 123.1 NA NA NA
4unk 1 P60174 99.6 0.0 X-RAY
 2015-02-04 ALA A:165 A:163 0.0 0.0 E -117.5 117.5 0.0 0.0 0.0 HOH
 5.443
 O
 O
ALA B:165 B:163 0.0 0.0 E -121.9 116.5 0.0 0.0 0.0 HOH
 5.546
 O
 O
4unl 1 P60174 99.6 0.0 X-RAY
 2015-02-04 ALA A:163 A:163 0.0 0.0 E -121.4 118.2 0.0 0.0 0.0 HOH
 5.561
 O
 O
ALA B:163 B:163 0.0 0.0 E -119.2 119.7 0.0 0.0 0.0 HOH
 5.504
 O
 O
4br1 1 P60174 100.0 0.0 X-RAY
 2013-06-12 ALA A:161 A:163 0.0 0.0 E -121.8 122.1 0.0 0.0 0.0 HOH
 5.443
 O
 O
ALA B:161 B:163 0.0 0.0 E -118.1 119.8 0.0 0.0 0.0 HOH
 5.461
 O
 O
6d43 1 P60174 100.0 0.0 X-RAY
 2018-05-16 ALA A:161 A:163 0.0 0.0 E -118.7 118.0 0.0 0.0 0.0 HOH
 5.438
 CB
 O
6d43 2 P60174 100.0 0.0 X-RAY
 2018-05-16 ALA B:161 B:163 0.0 0.0 E -113.4 114.7 0.0 0.0 0.0 HOH
 5.514
 O
 O
1r2r 1 P00939 98.39 0.0 X-RAY
 2003-12-23 ALA A:163 A:163 0.0 0.0 E -121.8 120.0 0.0 0.0 0.0 HOH
 5.504
 O
 O
ALA B:163 B:163 0.0 0.0 E -117.7 113.3 0.0 0.0 0.0 HOH
 4.851
 O
 O
ALA C:163 C:163 0.0 0.0 E -123.9 119.7 NA NA NA
ALA D:163 D:163 0.0 0.0 E -121.1 117.6 NA NA NA
1r2s 1 P00939 98.39 0.0 X-RAY
 2003-12-23 ALA A:163 A:163 0.0 0.0 E -115.2 120.4 0.0 0.0 0.0 HOH
 5.841
 O
 O
ALA B:163 B:163 0.0 0.0 E -112.4 123.3 0.0 0.0 0.0 HOH
 5.834
 O
 O
ALA C:163 C:163 0.0 0.0 E -112.7 124.3 NA NA NA
ALA D:163 D:163 0.0 0.0 E -121.1 120.2 NA NA NA
1r2t 1 P00939 98.39 0.0 X-RAY
 2003-12-23 ALA A:163 A:163 0.0 0.0 E -116.7 120.2 0.0 0.0 0.0 HOH
 5.543
 O
 O
ALA B:163 B:163 0.0 0.0 E -118.3 120.9 0.0 0.0 0.0 HOH
 5.610
 O
 O
4owg 1 P00939 98.39 0.0 X-RAY
 2014-03-05 ALA A:163 A:163 0.0 0.0 E -117.1 109.9 0.0 0.0 0.0 PEP
HOH
 7.001
5.466
 CB
O
 O2'
O
ALA B:163 B:163 0.0 0.0 E -117.8 107.9 0.0 0.0 0.0 PEP
HOH
 7.156
5.338
 CB
O
 O2'
O
6nlh 1 P60174 99.59 0.0 X-RAY
 2019-06-19 ALA A:160 A:163 0.0 0.0 E -113.0 115.8 0.0 0.0 0.0 NA
HOH
 9.536
4.852
 O
HB1
 NA
O
ALA B:160 E:163 0.0 0.0 E -117.3 117.9 0.0 0.0 0.0 BR
PO4
HOH
 6.893
9.943
5.765
 HB1
HB1
O
 BR
O2
O
ALA C:160 B:163 0.0 0.0 E -110.3 114.2 NA NA NA
ALA D:160 C:163 0.0 0.0 E -118.1 115.3 NA NA NA
ALA E:160 D:163 0.0 0.0 E -115.3 117.6 NA NA NA
ALA F:160 F:163 0.0 0.0 E -124.4 110.6 NA NA NA
ALA G:160 G:163 0.0 0.0 E -113.8 117.2 NA NA NA
ALA H:160 H:163 0.0 0.0 E -119.2 115.2 NA NA NA
1sw3 1 P00940 89.16 1e-162 X-RAY
 2004-08-24 ALA A:163 A:163 0.0 0.0 E -117.1 112.6 0.0 0.0 0.0 PGA
HOH
 7.004
5.463
 CB
O
 O2
O
ALA B:163 B:163 0.0 0.0 E -118.1 112.4 0.0 0.0 0.0 PGA
HOH
 6.917
5.451
 CB
O
 O2
O
1tph 1 P00940 89.39 7e-162 X-RAY
 1994-04-30 ALA A:162 1:163 0.0 0.0 E -123.5 113.9 0.0 0.0 0.0 PGH
HOH
 6.466
5.376
 CB
O
 O2
O
ALA B:162 2:163 0.0 0.0 E -114.6 111.9 0.0 0.0 0.0 PGH
HOH
 6.563
5.316
 CB
O
 O2
O
8tim 1 P00940 89.39 7e-162 X-RAY
 1999-02-16 ALA A:162 A:163 0.0 0.0 E -114.4 110.4 0.0 0.0 0.0
ALA B:162 B:163 0.0 0.0 E -117.9 117.0 0.0 0.0 0.0 HOH
 9.583
 CB
 O
1sw7 1 P00940 88.35 8e-162 X-RAY
 2004-08-24 ALA A:163 A:163 0.0 0.0 E -122.6 106.8 0.0 0.0 0.0 PGA
HOH
 6.978
4.833
 CB
O
 O2
O
ALA B:163 B:163 0.0 0.0 E -120.7 114.4 0.0 0.0 0.0 PGA
HOH
 7.019
2.869
 CB
N
 O2
O
1spq 1 P00940 89.39 1e-161 X-RAY
 2004-08-24 ALA A:162 A:163 0.0 0.0 E -112.8 119.9 0.0 0.0 0.0 HOH
 5.788
 O
 O
ALA B:162 B:163 0.0 0.0 E -116.7 117.5 0.0 0.0 0.0 HOH
 5.606
 O
 O
1tpb 1 P00940 88.98 2e-161 X-RAY
 1995-02-14 ALA A:162 1:163 0.0 0.0 E -120.0 117.8 0.0 0.0 0.0 PGH
HOH
 5.991
5.739
 CB
O
 O2
O
ALA B:162 2:163 0.0 0.0 E -113.0 108.9 0.0 0.0 0.0 PGH
HOH
 6.011
5.757
 CB
O
 O2
O
1sw0 1 P00940 88.76 6e-161 X-RAY
 2004-08-24 ALA A:163 A:163 0.0 0.0 E -117.6 115.6 0.0 0.0 0.0 PGA
HOH
 6.981
3.236
 CB
CB
 O2
O
ALA B:163 B:163 0.0 0.0 E -121.6 109.0 0.0 0.0 0.0 PGA
HOH
 6.926
5.296
 CB
O
 O2
O
1tpw 1 P00940 88.98 8e-161 X-RAY
 1995-04-20 ALA A:162 A:163 0.0 0.0 E -124.1 114.8 0.0 0.0 0.0 PGH
HOH
 6.604
3.122
 CB
N
 O2
O
ALA B:162 B:163 0.0 0.0 E -118.9 108.9 0.0 0.0 0.0 PGH
HOH
 6.643
8.160
 CB
O
 O2
O
1tpu 1 P00940 88.98 1e-160 X-RAY
 1995-04-20 ALA A:162 A:163 0.0 0.0 E -120.7 124.0 0.0 0.0 0.0 PGH
HOH
 6.250
5.609
 CB
O
 O2
O
ALA B:162 B:163 0.0 0.0 E -123.5 111.8 0.0 0.0 0.0 PGH
HOH
 6.221
5.527
 CB
O
 O2
O
4p61 1 P00940 88.76 2e-160 X-RAY
 2014-08-27 ALA A:163 A:163 0.0 0.0 E -117.3 120.1 0.0 0.0 0.0 HOH
 5.346
 O
 O
ALA B:163 B:163 0.0 0.0 E -120.8 121.7 0.0 0.0 0.0 HOH
 5.275
 O
 O
1tpc 1 P00940 88.57 2e-160 X-RAY
 1995-02-14 ALA A:162 1:163 0.0 0.0 E -126.6 110.9 0.0 0.0 0.0 PGH
HOH
 6.002
7.668
 CB
CB
 O2
O
ALA B:162 2:163 0.0 0.0 E -112.5 113.3 0.0 0.0 0.0 PGH
HOH
 5.961
7.569
 CB
CB
 O2
O
1ssd 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 ALA A:162 A:163 0.0 0.0 E -112.8 112.6 0.0 0.0 0.0 HOH
 5.527
 O
 O
ALA B:162 B:163 0.0 0.0 E -115.6 114.6 0.0 0.0 0.0 HOH
 4.793
 O
 O
1ssg 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 ALA A:162 A:163 0.0 0.0 E -117.8 117.4 0.0 0.0 0.0 PGA
HOH
 7.899
5.492
 CB
O
 O1
O
ALA B:162 B:163 0.0 0.0 E -109.9 110.1 0.0 0.0 0.0 PGA
HOH
 7.333
4.706
 CB
O
 O1
O
1sq7 1 P00940 88.98 4e-160 X-RAY
 2004-08-24 ALA A:162 A:163 0.0 0.0 E -122.5 111.7 0.0 0.0 0.0 HOH
 5.334
 O
 O
ALA B:162 B:163 0.0 0.0 E -129.1 113.6 0.0 0.0 0.0 HOH
 5.289
 O
 O
1tpv 1 P00940 88.57 1e-159 X-RAY
 1995-04-20 ALA A:162 A:163 0.0 0.0 E -126.3 112.7 0.0 0.0 0.0 PGH
HOH
 7.647
5.158
 CB
O
 O2
O
ALA B:162 B:163 0.0 0.0 E -120.6 108.9 0.0 0.0 0.0 PGH
HOH
 7.346
5.500
 CB
O
 O2
O
1su5 1 P00940 88.57 1e-159 X-RAY
 2004-08-24 ALA A:162 A:163 0.0 0.0 E -125.9 111.8 0.0 0.0 0.0 PGA
HOH
 6.490
8.733
 CB
N
 O1
O
ALA B:162 B:163 0.0 0.0 E -123.8 108.2 0.0 0.0 0.0 PGA
HOH
 6.487
5.552
 CB
O
 O1
O
1tim 1 P00940 86.53 5e-158 X-RAY
 1976-10-15 ALA A:162 A:163 0.0 0.0 E -112.5 120.5 0.0 0.0 0.0
ALA B:162 B:163 0.0 0.0 E -114.2 127.7 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60174-f1 1 P60174 100.0 0.0 ALA A:164 A:164 0.0 0.0 E -103.8 109.5