Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6979258 . G A CCDS53740.1:NM_001159287.1:c.700Gtc>Atc_NP_001152759.1:p.234V>I Homo sapiens triosephosphate isomerase 1 (TPI1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6up1 1 P60174 100.0 0.0 X-RAY
 2020-07-01 VAL A:200 A:196 59.0 0.381 T -131.0 -79.5 59.0 0.381 0.0 HOH
 3.614
 O
 O
VAL B:200 B:196 62.0 0.4 T -125.3 -72.2 62.0 0.4 0.0 HOH
 2.997
 O
 O
6up5 1 P60174 100.0 0.0 X-RAY
 2020-07-01 VAL A:200 A:196 55.0 0.355 T -137.1 -62.9 55.0 0.355 0.0 HOH
 3.641
 CG1
 O
VAL B:200 B:196 61.0 0.394 T -122.5 -71.5 61.0 0.394 0.0 HOH
 3.840
 CG1
 O
4poc 1 P60174 100.0 0.0 X-RAY
 2015-01-14 VAL A:202 A:196 57.0 0.368 T -121.6 -79.7 57.0 0.368 0.0 HOH
 3.310
 HG22
 O
VAL B:202 B:196 57.0 0.368 T -115.7 -79.0 57.0 0.368 0.0 HOH
 3.046
 HG22
 O
6c2g 1 P60174 99.6 0.0 X-RAY
 2018-03-21 VAL A:197 A:196 58.0 0.374 T -117.3 -79.2 58.0 0.374 0.0 HOH
 3.933
 CG1
 O
VAL B:197 B:196 57.0 0.368 T -118.6 -79.8 NA NA NA
VAL C:197 C:196 57.0 0.368 T -117.8 -80.1 NA NA NA
VAL D:197 D:196 58.0 0.374 T -117.8 -79.7 NA NA NA
4pod 1 P60174 99.6 0.0 X-RAY
 2015-01-14 VAL A:202 A:196 51.0 0.329 T -123.4 -80.4 51.0 0.329 0.0 HOH
 3.432
 HG22
 O
VAL B:202 B:196 56.0 0.361 T -120.1 -75.6 56.0 0.361 0.0 HOH
 3.466
 HG22
 O
1wyi 1 P60174 100.0 0.0 X-RAY
 2005-04-12 VAL A:198 A:196 52.0 0.335 T -107.0 -82.4 52.0 0.335 0.0 HOH
 3.681
 O
 O
VAL B:198 B:196 54.0 0.348 T -133.4 -80.6 54.0 0.348 0.0 HOH
 3.072
 O
 O
2jk2 1 P60174 100.0 0.0 X-RAY
 2008-07-01 VAL A:198 A:196 65.0 0.419 S -127.3 -86.0 65.0 0.419 0.0 HOH
 2.664
 CG2
 O
VAL B:198 B:196 54.0 0.348 T -115.7 -77.2 54.0 0.348 0.0 HOH
 2.595
 O
 O
6up8 1 P60174 99.6 0.0 X-RAY
 2020-07-01 VAL A:200 A:196 54.0 0.348 T -133.0 -68.7 54.0 0.348 0.0 HOH
 4.491
 CG2
 O
VAL B:200 B:196 56.0 0.361 T -119.9 -74.5 56.0 0.361 0.0 HOH
 3.635
 CG2
 O
6upf 1 P60174 99.6 0.0 X-RAY
 2020-07-01 VAL A:200 A:196 59.0 0.381 T -120.1 -74.1 59.0 0.381 0.0 HOH
 2.770
 O
 O
VAL B:200 B:196 60.0 0.387 T -124.6 -71.1 60.0 0.387 0.0 HOH
 2.810
 O
 O
1hti 1 P60174 100.0 0.0 X-RAY
 1995-01-26 VAL A:196 A:196 64.0 0.413 T -122.7 -72.0 64.0 0.413 0.0
VAL B:196 B:196 53.0 0.342 T -112.2 -71.7 53.0 0.342 0.0
4zvj 1 P60174 99.6 0.0 X-RAY
 2016-03-09 VAL A:202 A:196 60.0 0.387 T -129.9 -79.3 60.0 0.387 0.0 HOH
 3.358
 HG22
 O
VAL B:202 B:196 54.0 0.348 T -115.3 -78.9 54.0 0.348 0.0 HOH
 3.126
 HG22
 O
2vom 1 P60174 99.6 0.0 X-RAY
 2008-06-17 VAL A:198 A:196 52.0 0.335 T -119.3 -76.4 52.0 0.335 0.0 HOH
 2.665
 O
 O
VAL B:198 B:196 56.0 0.361 T -122.7 -73.6 56.0 0.361 0.0 HOH
 3.736
 CA
 O
VAL C:198 C:196 54.0 0.348 T -117.2 -67.5 NA NA NA
VAL D:198 D:196 54.0 0.348 T -118.3 -85.0 NA NA NA
4unk 1 P60174 99.6 0.0 X-RAY
 2015-02-04 VAL A:198 A:196 57.0 0.368 T -124.9 -66.8 57.0 0.368 0.0 HOH
 2.685
 O
 O
VAL B:198 B:196 57.0 0.368 T -122.8 -65.4 57.0 0.368 0.0 HOH
 2.517
 O
 O
4unl 1 P60174 99.6 0.0 X-RAY
 2015-02-04 VAL A:196 A:196 56.0 0.361 T -116.7 -73.6 56.0 0.361 0.0 HOH
 4.047
 CG1
 O
VAL B:196 B:196 58.0 0.374 T -125.1 -72.0 58.0 0.374 0.0 HOH
 2.870
 O
 O
4br1 1 P60174 100.0 0.0 X-RAY
 2013-06-12 VAL A:194 A:196 53.0 0.342 T -114.7 -77.1 53.0 0.342 0.0 HOH
 3.760
 CG1
 O
VAL B:194 B:196 58.0 0.374 T -119.6 -74.4 58.0 0.374 0.0 HOH
 2.682
 O
 O
6d43 1 P60174 100.0 0.0 X-RAY
 2018-05-16 VAL A:194 A:196 56.0 0.361 T -117.7 -80.2 56.0 0.361 0.0 HOH
 3.890
 CG2
 O
6d43 2 P60174 100.0 0.0 X-RAY
 2018-05-16 VAL B:194 B:196 54.0 0.348 T -108.2 -74.3 54.0 0.348 0.0 HOH
 2.641
 O
 O
1r2r 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:196 A:196 57.0 0.368 T -121.2 -74.4 57.0 0.368 0.0 HOH
 3.658
 N
 O
VAL B:196 B:196 60.0 0.387 T -123.3 -76.7 60.0 0.387 0.0 DMS
HOH
 5.540
2.740
 O
O
 O
O
VAL C:196 C:196 60.0 0.387 T -116.1 -80.1 NA NA NA
VAL D:196 D:196 57.0 0.368 T -122.1 -78.8 NA NA NA
1r2s 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:196 A:196 59.0 0.381 T -119.0 -81.0 59.0 0.381 0.0 HOH
 3.432
 CG2
 O
VAL B:196 B:196 57.0 0.368 T -117.0 -80.1 57.0 0.368 0.0 HOH
 3.377
 CG2
 O
VAL C:196 C:196 58.0 0.374 T -119.0 -77.0 NA NA NA
VAL D:196 D:196 58.0 0.374 T -117.9 -76.2 NA NA NA
1r2t 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:196 A:196 58.0 0.374 T -117.5 -79.6 58.0 0.374 0.0 HOH
 2.387
 O
 O
VAL B:196 B:196 56.0 0.361 T -110.6 -80.6 56.0 0.361 0.0 HOH
 3.379
 O
 O
4owg 1 P00939 98.39 0.0 X-RAY
 2014-03-05 VAL A:196 A:196 61.0 0.394 T -121.4 -82.3 61.0 0.394 0.0 HOH
 2.664
 O
 O
VAL B:196 B:196 58.0 0.374 T -124.7 -79.1 58.0 0.374 0.0 HOH
 6.566
 N
 O
6nlh 1 P60174 99.59 0.0 X-RAY
 2019-06-19 VAL A:193 A:196 61.0 0.394 T -132.0 -80.6 61.0 0.394 0.0 NA
HOH
 6.229
3.270
 H
HG22
 NA
O
VAL B:193 E:196 56.0 0.361 T -115.7 -75.5 56.0 0.361 0.0 HOH
 3.343
 HG22
 O
VAL C:193 B:196 57.0 0.368 T -134.7 -75.7 NA NA NA
VAL D:193 C:196 55.0 0.355 T -114.0 -80.2 NA NA NA
VAL E:193 D:196 59.0 0.381 T -131.7 -83.7 NA NA NA
VAL F:193 F:196 56.0 0.361 T -118.1 -75.8 NA NA NA
VAL G:193 G:196 59.0 0.381 T -127.2 -81.2 NA NA NA
VAL H:193 H:196 54.0 0.348 T -120.8 -76.3 NA NA NA
1sw3 1 P00940 89.16 1e-162 X-RAY
 2004-08-24 VAL A:196 A:196 58.0 0.374 T -126.3 -84.3 58.0 0.374 0.0 HOH
 3.869
 CG2
 O
VAL B:196 B:196 59.0 0.381 T -124.3 -74.6 59.0 0.381 0.0 HOH
 3.720
 CG2
 O
1tph 1 P00940 89.39 7e-162 X-RAY
 1994-04-30 VAL A:195 1:196 54.0 0.348 T -116.4 -83.2 54.0 0.348 0.0 HOH
 4.195
 CG2
 O
VAL B:195 2:196 55.0 0.355 T -118.6 -74.6 55.0 0.355 0.0 HOH
 3.795
 CG2
 O
8tim 1 P00940 89.39 7e-162 X-RAY
 1999-02-16 VAL A:195 A:196 55.0 0.355 T -127.6 -74.1 55.0 0.355 0.0 HOH
 5.528
 O
 O
VAL B:195 B:196 60.0 0.387 T -111.5 -76.8 60.0 0.387 0.0
1sw7 1 P00940 88.35 8e-162 X-RAY
 2004-08-24 VAL A:196 A:196 61.0 0.394 T -110.8 -77.9 61.0 0.394 0.0 HOH
 5.652
 O
 O
VAL B:196 B:196 59.0 0.381 T -118.7 -83.9 59.0 0.381 0.0 HOH
 5.346
 O
 O
1spq 1 P00940 89.39 1e-161 X-RAY
 2004-08-24 VAL A:195 A:196 57.0 0.368 T -122.0 -82.1 57.0 0.368 0.0 HOH
 2.995
 O
 O
VAL B:195 B:196 58.0 0.374 T -123.8 -89.6 58.0 0.374 0.0 HOH
 2.965
 O
 O
1tpb 1 P00940 88.98 2e-161 X-RAY
 1995-02-14 VAL A:195 1:196 54.0 0.348 T -118.8 -83.0 54.0 0.348 0.0 HOH
 4.144
 CG2
 O
VAL B:195 2:196 57.0 0.368 T -118.1 -81.3 57.0 0.368 0.0 HOH
 5.888
 CG2
 O
1sw0 1 P00940 88.76 6e-161 X-RAY
 2004-08-24 VAL A:196 A:196 57.0 0.368 T -120.5 -80.8 57.0 0.368 0.0 HOH
 3.129
 O
 O
VAL B:196 B:196 55.0 0.355 T -116.7 -89.8 55.0 0.355 0.0 HOH
 4.131
 CG1
 O
1tpw 1 P00940 88.98 8e-161 X-RAY
 1995-04-20 VAL A:195 A:196 55.0 0.355 T -134.8 -82.2 55.0 0.355 0.0 HOH
 3.911
 CG2
 O
VAL B:195 B:196 58.0 0.374 T -116.1 -75.2 58.0 0.374 0.0 HOH
 4.034
 CG1
 O
1tpu 1 P00940 88.98 1e-160 X-RAY
 1995-04-20 VAL A:195 A:196 56.0 0.361 T -118.4 -94.0 56.0 0.361 0.0 HOH
 4.217
 O
 O
VAL B:195 B:196 57.0 0.368 T -124.6 -78.3 57.0 0.368 0.0 HOH
 3.727
 CG2
 O
4p61 1 P00940 88.76 2e-160 X-RAY
 2014-08-27 VAL A:196 A:196 55.0 0.355 T -117.2 -78.3 55.0 0.355 0.0 HOH
 3.032
 O
 O
VAL B:196 B:196 54.0 0.348 T -117.7 -78.8 54.0 0.348 0.0 HOH
 2.754
 O
 O
1tpc 1 P00940 88.57 2e-160 X-RAY
 1995-02-14 VAL A:195 1:196 52.0 0.335 T -120.5 -81.3 52.0 0.335 0.0 HOH
 4.175
 CG2
 O
VAL B:195 2:196 57.0 0.368 T -120.1 -76.7 57.0 0.368 0.0 HOH
 3.606
 O
 O
1ssd 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 VAL A:195 A:196 55.0 0.355 T -130.6 -84.8 55.0 0.355 0.0
VAL B:195 B:196 56.0 0.361 T -124.0 -85.0 56.0 0.361 0.0
1ssg 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 VAL A:195 A:196 55.0 0.355 T -130.9 -71.8 55.0 0.355 0.0 HOH
 5.207
 O
 O
VAL B:195 B:196 58.0 0.374 T -124.8 -80.8 58.0 0.374 0.0 GOL
HOH
 4.801
7.406
 O
O
 O2
O
1sq7 1 P00940 88.98 4e-160 X-RAY
 2004-08-24 VAL A:195 A:196 60.0 0.387 T -121.7 -87.3 60.0 0.387 0.0 HOH
 3.628
 CG2
 O
VAL B:195 B:196 58.0 0.374 T -110.4 -78.2 58.0 0.374 0.0 HOH
 4.973
 O
 O
1tpv 1 P00940 88.57 1e-159 X-RAY
 1995-04-20 VAL A:195 A:196 54.0 0.348 T -121.9 -88.3 54.0 0.348 0.0 HOH
 2.802
 O
 O
VAL B:195 B:196 60.0 0.387 T -128.8 -70.7 60.0 0.387 0.0 HOH
 3.649
 CG1
 O
1su5 1 P00940 88.57 1e-159 X-RAY
 2004-08-24 VAL A:195 A:196 62.0 0.4 T -116.9 -83.1 62.0 0.4 0.0 SO4
HOH
 4.276
3.905
 O
CG2
 O4
O
VAL B:195 B:196 56.0 0.361 T -114.2 -81.9 56.0 0.361 0.0 SO4
HOH
 4.460
4.948
 O
CG2
 O3
O
1tim 1 P00940 86.53 5e-158 X-RAY
 1976-10-15 VAL A:195 A:196 43.0 0.277 H -96.7 -55.2 43.0 0.277 0.0
VAL B:195 B:196 52.0 0.335 T -97.5 -55.1 52.0 0.335 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60174-f1 1 P60174 100.0 0.0 VAL A:197 A:197 52.0 0.335 T -121.9 -73.4