Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 79689850 . T A CCDS9017.1:NM_001135805.1:c.476cTg>cAg_NP_001129277.1:p.159L>Q Homo sapiens synaptotagmin 1 (SYT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5w5c 6 P21707 100.0 0.0 X-RAY
 2017-08-23 LEU F:19 F:158 34.0 NA E -109.2 134.2 34.0 NA NA
5ccg 5 P21707 100.0 0.0 X-RAY
 2015-08-12 LEU E:18 E:158 0.0 0.0 E -104.0 125.8 0.0 0.0 0.0
LEU F:18 F:158 0.0 0.0 E -104.0 124.9 0.0 0.0 0.0 CA
 9.796
 CD1
 CA
LEU K:18 K:158 0.0 0.0 E -103.2 125.4 NA NA NA
5cch 5 P21707 100.0 0.0 X-RAY
 2015-08-12 LEU E:18 E:158 0.0 0.0 E -88.6 127.3 0.0 0.0 0.0
LEU F:18 F:158 0.0 0.0 E -87.1 126.5 0.0 0.0 0.0
5cci 5 P21707 100.0 0.0 X-RAY
 2015-08-12 LEU E:18 E:158 2.0 0.012 E -89.5 128.6 2.0 0.012 0.0
LEU F:18 F:158 0.0 0.0 E -88.4 128.9 0.0 0.0 0.0
6mti 2 P21707 100.0 0.0 EM
 2019-04-24 LEU B:18 2:158 2.0 0.012 E -89.5 128.6 2.0 0.012 0.0
LEU C:18 3:158 2.0 0.012 E -89.5 128.6 2.0 0.012 0.0
LEU D:18 4:158 2.0 0.012 E -89.5 128.6 2.0 0.012 0.0
LEU E:18 5:158 1.0 0.006 E -89.5 128.6 1.0 0.006 0.0
2r83 1 P21579 99.65 0.0 X-RAY
 2008-02-12 LEU A:21 A:158 0.0 0.0 E -92.5 128.6 0.0 0.0 0.0
LEU B:21 B:158 0.0 0.0 E -91.5 131.9 0.0 0.0 0.0 HOH
 9.637
 CD1
 O
5kj7 5 P21707 100.0 0.0 X-RAY
 2016-10-19 LEU E:18 E:158 0.0 0.0 E -106.6 118.4 0.0 0.0 0.0
LEU F:18 F:158 0.0 0.0 E -107.3 128.5 NA NA NA
LEU K:18 K:158 0.0 0.0 E -106.2 118.3 NA NA NA
5kj8 5 P21707 100.0 0.0 X-RAY
 2016-10-19 LEU E:18 E:158 0.0 0.0 E -101.7 125.4 0.0 0.0 0.0
LEU F:18 F:158 0.0 0.0 E -102.4 123.8 NA NA NA
LEU K:18 K:158 0.0 0.0 E -100.2 124.7 NA NA NA
2k8m 1 Q6AI31 100.0 2e-89 NMR
 2009-03-17 LEU A:19 A:19 13.0 0.076 E -107.3 126.9 13.0 0.076 0.0
LEU D:19 D:19 14.0 0.082 E -104.9 126.9 14.0 0.082 0.0
2ki6 1 P21579 100.0 2e-89 NMR
 2010-03-09 LEU A:19 A:19 12.0 0.071 E -94.7 132.9 12.0 0.071 0.0
LEU F:19 F:19 15.0 0.088 E -94.7 133.0 15.0 0.088 0.0
6mti 1 P21707 100.0 1e-88 EM
 2019-04-24 LEU A:18 1:158 2.0 0.012 E -89.5 128.6 2.0 0.012 0.0
LEU F:18 6:158 1.0 0.006 E -89.5 128.6 1.0 0.006 0.0
4wee 1 P21707 100.0 1e-88 X-RAY
 2014-10-01 LEU A:36 A:158 1.0 0.006 E -87.8 127.2 1.0 0.006 0.0 HOH
 5.894
 HD11
 O
5t0r 1 P46096 100.0 6e-88 X-RAY
 2017-06-14 LEU A:19 A:158 0.0 0.0 E -88.4 124.8 0.0 0.0 0.0 HOH
 6.676
 C
 O
5vfe 1 P46096 100.0 6e-88 X-RAY
 2018-04-11 LEU A:19 A:158 0.0 0.0 E -78.6 133.5 0.0 0.0 0.0 HOH
 6.737
 C
 O
LEU B:19 B:158 0.0 0.0 E -90.1 122.7 NA NA NA
3f00 1 P21579 100.0 7e-88 X-RAY
 2009-09-08 LEU A:36 A:158 0.0 0.0 E -92.9 127.0 0.0 0.0 0.0 HOH
 6.390
 CD1
 O
3f01 1 P21579 100.0 7e-88 X-RAY
 2009-10-06 LEU A:36 A:158 0.0 0.0 E -91.1 127.3 0.0 0.0 0.0 HOH
 4.300
 O
 O
3f04 1 P21579 100.0 7e-88 X-RAY
 2009-09-08 LEU A:36 A:158 0.0 0.0 E -86.9 127.2 0.0 0.0 0.0 HOH
 6.477
 CD1
 O
3f05 1 P21579 100.0 7e-88 X-RAY
 2009-10-06 LEU A:36 A:158 0.0 0.0 E -88.8 127.9 0.0 0.0 0.0 HOH
 6.454
 O
 O
1rsy 1 P21707 100.0 3e-87 X-RAY
 1995-05-08 LEU A:44 A:158 0.0 0.0 E -88.0 130.7 0.0 0.0 0.0 HOH
 6.511
 CD1
 O
6cxw 1 P21707 87.5 5e-71 X-RAY
 2019-04-17 LEU A:19 A:158 0.0 0.0 E -67.6 133.2 0.0 0.0 0.0 HOH
 6.471
 HD12
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21579-f1 1 P21579 100.0 0.0 LEU A:159 A:159 0.0 0.0 E -82.3 125.4