Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 79689876 . G A CCDS9017.1:NM_001135805.1:c.502Gaa>Aaa_NP_001129277.1:p.168E>K Homo sapiens synaptotagmin 1 (SYT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5w5c 6 P21707 100.0 0.0 X-RAY
 2017-08-23 GLU F:28 F:167 66.0 NA S 64.7 38.9 66.0 NA NA
5ccg 5 P21707 100.0 0.0 X-RAY
 2015-08-12 GLU E:27 E:167 121.0 0.637 S 54.9 65.7 121.0 0.637 0.0
GLU F:27 F:167 115.0 0.605 S 53.8 63.8 115.0 0.605 0.0 HOH
 9.881
 OE2
 O
GLU K:27 K:167 123.0 0.647 -99.5 67.0 NA NA NA
5cch 5 P21707 100.0 0.0 X-RAY
 2015-08-12 GLU E:27 E:167 123.0 0.647 S 59.7 37.4 123.0 0.647 0.0
GLU F:27 F:167 127.0 0.668 S 58.2 37.6 127.0 0.668 0.0
5cci 5 P21707 100.0 0.0 X-RAY
 2015-08-12 GLU E:27 E:167 130.0 0.684 S 52.0 36.0 130.0 0.684 0.0
GLU F:27 F:167 112.0 0.589 S 48.1 37.5 112.0 0.589 0.0
6mti 2 P21707 100.0 0.0 EM
 2019-04-24 GLU B:27 2:167 129.0 0.679 S 52.0 35.9 129.0 0.679 0.0
GLU C:27 3:167 129.0 0.679 S 51.9 36.0 127.0 0.668 0.011 Q:P60881:0.011
GLU D:27 4:167 129.0 0.679 S 52.0 36.0 122.0 0.642 0.037 CA:P60881:0.037
GLU E:27 5:167 129.0 0.679 S 51.9 36.0 129.0 0.679 0.0
2r83 1 P21579 99.65 0.0 X-RAY
 2008-02-12 GLU A:30 A:167 124.0 0.653 51.2 39.9 124.0 0.653 0.0 CL
HOH
 7.497
4.239
 N
OE1
 CL
O
GLU B:30 B:167 125.0 0.658 51.5 34.5 125.0 0.658 0.0 HOH
 3.616
 CA
 O
5kj7 5 P21707 100.0 0.0 X-RAY
 2016-10-19 GLU E:27 E:167 120.0 0.632 S 55.1 67.4 120.0 0.632 0.0
GLU F:27 F:167 112.0 0.589 S 62.4 39.2 NA NA NA
GLU K:27 K:167 124.0 0.653 S -91.1 68.8 NA NA NA
5kj8 5 P21707 100.0 0.0 X-RAY
 2016-10-19 GLU E:27 E:167 125.0 0.658 S 56.9 54.7 125.0 0.658 0.0
GLU F:27 F:167 108.0 0.568 S 50.0 53.3 NA NA NA
GLU K:27 K:167 127.0 0.668 S -89.7 55.9 NA NA NA
2k8m 1 Q6AI31 100.0 2e-89 NMR
 2009-03-17 GLU A:28 A:28 141.0 0.742 S 67.6 25.2 141.0 0.742 0.0
GLU D:28 D:28 143.0 0.753 S 66.8 32.2 143.0 0.753 0.0
2ki6 1 P21579 100.0 2e-89 NMR
 2010-03-09 GLU A:28 A:28 142.0 0.747 S 60.4 75.1 81.0 0.426 0.321 D:Q99584:0.321
GLU F:28 F:28 142.0 0.747 S 65.4 50.9 64.0 0.337 0.41 D:Q99584:0.163
C:Q99584:0.247
6mti 1 P21707 100.0 1e-88 EM
 2019-04-24 GLU A:27 1:167 130.0 0.684 S 52.0 36.0 127.0 0.668 0.016 C:P21707:0.016
GLU F:27 6:167 129.0 0.679 S 52.0 36.0 117.0 0.616 0.063 U:P60881:0.063
4wee 1 P21707 100.0 1e-88 X-RAY
 2014-10-01 GLU A:45 A:167 124.0 0.653 58.4 39.5 124.0 0.653 0.0 NA
NA
HOH
 9.517
6.606
6.729
 O
O
C
 NA
NA
O
5t0r 1 P46096 100.0 6e-88 X-RAY
 2017-06-14 GLU A:28 A:167 140.0 0.737 S 53.6 34.7 140.0 0.737 0.0 HOH
 2.614
 O
 O
5vfe 1 P46096 100.0 6e-88 X-RAY
 2018-04-11 GLU A:28 A:167 116.0 0.611 S 58.4 37.0 116.0 0.611 0.0 SO4
HOH
 7.327
2.941
 N
O
 O4
O
GLU B:28 B:167 125.0 0.658 S 59.1 31.8 NA NA NA
3f00 1 P21579 100.0 7e-88 X-RAY
 2009-09-08 GLU A:45 A:167 111.0 0.584 58.1 36.6 111.0 0.584 0.0 HOH
 2.711
 O
 O
3f01 1 P21579 100.0 7e-88 X-RAY
 2009-10-06 GLU A:45 A:167 133.0 0.7 58.9 38.1 133.0 0.7 0.0 HOH
 2.687
 O
 O
3f04 1 P21579 100.0 7e-88 X-RAY
 2009-09-08 GLU A:45 A:167 123.0 0.647 58.6 38.6 123.0 0.647 0.0 HOH
 2.771
 O
 O
3f05 1 P21579 100.0 7e-88 X-RAY
 2009-10-06 GLU A:45 A:167 125.0 0.658 S 59.9 35.9 125.0 0.658 0.0 HOH
 2.505
 OE1
 O
1rsy 1 P21707 100.0 3e-87 X-RAY
 1995-05-08 GLU A:53 A:167 117.0 0.616 S 52.1 36.8 117.0 0.616 0.0 HOH
 2.606
 OE1
 O
6cxw 1 P21707 87.5 5e-71 X-RAY
 2019-04-17 GLU A:28 A:167 133.0 0.7 S 60.6 37.1 133.0 0.7 0.0 HOH
 2.502
 OE2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21579-f1 1 P21579 100.0 0.0 GLU A:168 A:168 116.0 0.611 S 58.4 35.2