Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 79693197 . G A CCDS9017.1:NM_001135805.1:c.676Gtg>Atg_NP_001129277.1:p.226V>M Homo sapiens synaptotagmin 1 (SYT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5w5c 6 P21707 100.0 0.0 X-RAY
 2017-08-23 VAL F:86 F:225 32.0 NA E -147.8 139.4 32.0 NA NA
5ccg 5 P21707 100.0 0.0 X-RAY
 2015-08-12 VAL E:85 E:225 10.0 0.065 E -115.9 123.2 10.0 0.065 0.0
VAL F:85 F:225 25.0 0.161 E -116.4 121.2 25.0 0.161 0.0
VAL K:85 K:225 0.0 0.0 E -115.2 123.4 NA NA NA
5cch 5 P21707 100.0 0.0 X-RAY
 2015-08-12 VAL E:85 E:225 7.0 0.045 E -118.8 130.9 7.0 0.045 0.0
VAL F:85 F:225 6.0 0.039 E -118.0 119.4 6.0 0.039 0.0
5cci 5 P21707 100.0 0.0 X-RAY
 2015-08-12 VAL E:85 E:225 9.0 0.058 E -123.6 124.4 9.0 0.058 0.0
VAL F:85 F:225 4.0 0.026 E -125.7 123.0 4.0 0.026 0.0
6mti 2 P21707 100.0 0.0 EM
 2019-04-24 VAL B:85 2:225 9.0 0.058 E -123.5 124.4 9.0 0.058 0.0
VAL C:85 3:225 10.0 0.065 E -123.6 124.5 10.0 0.065 0.0
VAL D:85 4:225 10.0 0.065 E -123.6 124.3 10.0 0.065 0.0
VAL E:85 5:225 10.0 0.065 E -123.6 124.5 10.0 0.065 0.0
2r83 1 P21579 99.65 0.0 X-RAY
 2008-02-12 VAL A:88 A:225 0.0 0.0 E -119.1 124.6 0.0 0.0 0.0
VAL B:88 B:225 0.0 0.0 E -117.9 124.1 0.0 0.0 0.0 HOH
 4.492
 CG1
 O
5kj7 5 P21707 100.0 0.0 X-RAY
 2016-10-19 VAL E:85 E:225 11.0 0.071 E -119.4 125.4 11.0 0.071 0.0
VAL F:85 F:225 25.0 0.161 E -120.6 122.6 NA NA NA
VAL K:85 K:225 1.0 0.006 E -119.2 125.4 NA NA NA
5kj8 5 P21707 100.0 0.0 X-RAY
 2016-10-19 VAL E:85 E:225 8.0 0.052 E -115.6 122.4 8.0 0.052 0.0
VAL F:85 F:225 12.0 0.077 E -115.1 123.0 NA NA NA
VAL K:85 K:225 0.0 0.0 E -115.9 123.6 NA NA NA
2k8m 1 Q6AI31 100.0 2e-89 NMR
 2009-03-17 VAL A:86 A:86 30.0 0.194 E -124.8 132.6 30.0 0.194 0.0
VAL D:86 D:86 27.0 0.174 E -131.8 143.1 27.0 0.174 0.0
2ki6 1 P21579 100.0 2e-89 NMR
 2010-03-09 VAL A:86 A:86 32.0 0.206 E -132.1 123.4 32.0 0.206 0.0
VAL F:86 F:86 31.0 0.2 E -132.2 123.5 31.0 0.2 0.0
6mti 1 P21707 100.0 1e-88 EM
 2019-04-24 VAL A:85 1:225 10.0 0.065 E -123.5 124.5 10.0 0.065 0.0
VAL F:85 6:225 9.0 0.058 E -123.6 124.4 9.0 0.058 0.0
4wee 1 P21707 100.0 1e-88 X-RAY
 2014-10-01 VAL A:103 A:225 6.0 0.039 E -117.8 135.9 6.0 0.039 0.0 HOH
 4.925
 HG22
 O
5t0r 1 P46096 100.0 6e-88 X-RAY
 2017-06-14 VAL A:86 A:225 1.0 0.006 E -108.0 123.1 1.0 0.006 0.0 HOH
 4.135
 CG1
 O
5vfe 1 P46096 100.0 6e-88 X-RAY
 2018-04-11 VAL A:86 A:225 3.0 0.019 E -116.3 129.0 3.0 0.019 0.0 HOH
 4.143
 CG2
 O
VAL B:86 B:225 1.0 0.006 E -117.2 130.5 NA NA NA
3f00 1 P21579 100.0 7e-88 X-RAY
 2009-09-08 VAL A:103 A:225 3.0 0.019 E -116.7 137.1 3.0 0.019 0.0 HOH
 5.903
 CG2
 O
3f01 1 P21579 100.0 7e-88 X-RAY
 2009-10-06 VAL A:103 A:225 6.0 0.039 E -119.3 136.6 6.0 0.039 0.0 HOH
 6.274
 CG1
 O
3f04 1 P21579 100.0 7e-88 X-RAY
 2009-09-08 VAL A:103 A:225 7.0 0.045 E -117.8 135.9 7.0 0.045 0.0 HOH
 5.707
 CG2
 O
3f05 1 P21579 100.0 7e-88 X-RAY
 2009-10-06 VAL A:103 A:225 6.0 0.039 E -115.6 136.0 6.0 0.039 0.0 HOH
 5.893
 CG2
 O
1rsy 1 P21707 100.0 3e-87 X-RAY
 1995-05-08 VAL A:111 A:225 8.0 0.052 E -112.0 133.8 8.0 0.052 0.0 HOH
 7.523
 CG2
 O
6cxw 1 P21707 87.5 5e-71 X-RAY
 2019-04-17 VAL A:88 A:227 11.0 0.071 E -116.5 130.1 11.0 0.071 0.0 HOH
 2.921
 HG11
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21579-f1 1 P21579 100.0 0.0 VAL A:226 A:226 1.0 0.006 E -120.0 128.1