Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 79747382 . A C CCDS9017.1:NM_001135805.1:c.911gAt>gCt_NP_001129277.1:p.304D>A Homo sapiens synaptotagmin 1 (SYT1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5w5c 6 P21707 100.0 0.0 X-RAY
 2017-08-23 ASP F:164 F:303 66.0 0.44 S -114.2 151.6 66.0 0.44 0.0 GOL
HOH
 4.928
2.715
 O
OD1
 O1
O
5ccg 5 P21707 100.0 0.0 X-RAY
 2015-08-12 ASP E:163 E:303 35.0 0.233 S -64.8 137.4 35.0 0.233 0.0 CA
CA
 3.176
2.881
 CB
N
 CA
CA
ASP F:163 F:303 116.0 0.773 62.5 360.0 116.0 0.773 0.0 CA
 3.393
 OD2
 CA
ASP K:163 K:303 39.0 0.26 S -60.8 138.6 NA NA NA
5cch 5 P21707 100.0 0.0 X-RAY
 2015-08-12 ASP E:163 E:303 80.0 0.533 B -138.8 155.9 80.0 0.533 0.0 CA
CA
 3.224
3.854
 CB
CA
 CA
CA
ASP F:163 NA:NA DO NA DO DO DO NA NA NA
5cci 5 P21707 100.0 0.0 X-RAY
 2015-08-12 ASP E:163 E:303 43.0 0.287 S -96.9 159.3 43.0 0.287 0.0 MG
 2.207
 OD2
 MG
ASP F:163 NA:NA DO NA DO DO DO NA NA NA
6mti 2 P21707 100.0 0.0 EM
 2019-04-24 ASP B:163 2:584 44.0 0.293 S -96.9 159.3 44.0 0.293 0.0 MG
 2.205
 OD2
 MG
ASP C:163 3:584 41.0 0.273 S -96.9 159.2 41.0 0.273 0.0 MG
 2.207
 OD2
 MG
ASP D:163 4:584 42.0 0.28 S -96.9 159.3 42.0 0.28 0.0 MG
 2.206
 OD2
 MG
ASP E:163 5:584 42.0 0.28 S -96.9 159.3 42.0 0.28 0.0 MG
 2.208
 OD2
 MG
2r83 1 P21579 99.65 0.0 X-RAY
 2008-02-12 ASP A:166 A:303 35.0 0.233 S -116.3 126.8 35.0 0.233 0.0 HOH
 2.343
 OD1
 O
ASP B:166 B:303 38.0 0.253 S -116.2 127.0 38.0 0.253 0.0 HOH
 2.548
 OD1
 O
5kj7 5 P21707 100.0 0.0 X-RAY
 2016-10-19 ASP E:163 E:303 35.0 0.233 S -64.4 137.8 35.0 0.233 0.0 CA
CA
 3.035
2.980
 CG
N
 CA
CA
ASP F:163 F:303 111.0 0.74 60.4 360.0 NA NA NA
ASP K:163 K:303 43.0 0.287 S -63.9 138.4 NA NA NA
5kj8 5 P21707 100.0 0.0 X-RAY
 2016-10-19 ASP E:163 E:303 49.0 0.327 S -34.8 127.7 49.0 0.327 0.0 CA
CA
 2.195
2.568
 OD2
N
 CA
CA
ASP F:163 F:303 125.0 0.833 60.8 360.0 NA NA NA
ASP K:163 K:303 38.0 0.253 S -115.8 139.3 NA NA NA
2lha 1 P21579 100.0 4e-96 NMR
 2012-05-02 ASP A:34 A:303 27.0 0.18 S -75.3 133.8 27.0 0.18 0.0
5w5d 6 P21707 100.0 4e-96 X-RAY
 2017-08-23 ASP F:34 F:303 108.0 0.72 S -113.9 157.5 108.0 0.72 0.0 HOH
 5.060
 O
 O
5t0s 1 P46096 100.0 2e-95 X-RAY
 2017-06-14 ASP A:33 A:303 41.0 0.273 S -90.9 130.0 41.0 0.273 0.0 CD
HOH
 2.722
2.302
 OD2
O
 CD
O
2yoa 1 P21707 100.0 3e-95 X-RAY
 2013-03-20 ASP A:34 A:303 25.0 0.167 S -126.1 125.5 25.0 0.167 0.0 CA
CA
CA
SEP
CA
HOH
 2.359
2.344
6.308
3.301
6.499
2.679
 OD2
OD1
OD1
OD1
OD2
OD2
 CA
CA
CA
O
CA
O
ASP B:34 B:303 28.0 0.187 S -125.6 125.1 NA NA NA
6tz3 1 P21579 100.0 3e-95 X-RAY
 2020-05-13 ASP A:39 A:304 40.0 0.267 S -103.6 140.8 40.0 0.267 0.0 HOH
 2.395
 HA
 O
1tjm 1 P21707 100.0 4e-95 X-RAY
 2004-09-28 ASP A:41 A:303 43.0 0.287 S -89.4 125.5 43.0 0.287 0.0 SR
HOH
 2.518
2.494
 OD1
OD2
 SR
H2
1tjx 1 P21707 100.0 4e-95 X-RAY
 2004-11-23 ASP A:41 A:303 40.0 0.267 S -126.1 127.1 40.0 0.267 0.0 CA
CA
HOH
 2.450
2.514
1.952
 OD1
OD1
OD2
 CA
CA
H2
1uov 1 P21707 100.0 4e-95 X-RAY
 2004-09-09 ASP A:41 A:303 44.0 0.293 S -133.5 156.1 44.0 0.293 0.0 CA
CA
CA
HOH
 2.374
2.429
3.540
2.592
 OD1
OD2
OD2
OD2
 CA
CA
CA
O
1uow 1 P21707 100.0 4e-95 X-RAY
 2004-09-16 ASP A:41 A:303 40.0 0.267 S -126.0 127.0 40.0 0.267 0.0 CA
CA
HOH
 2.458
2.506
2.440
 OD1
OD1
OD2
 CA
CA
O
4v11 1 P21579 100.0 2e-94 X-RAY
 2015-02-25 ASP A:32 A:304 29.0 0.193 -123.7 149.2 29.0 0.193 0.0 CA
CA
HOH
 2.380
2.375
2.590
 OD2
OD1
OD2
 CA
CA
O
6u4w 1 P21579 99.34 2e-94 X-RAY
 2020-05-13 ASP A:39 A:304 81.0 0.54 S -89.9 94.6 81.0 0.54 0.0 HOH
 3.049
 OD2
 O
6u4u 1 P21579 99.34 2e-94 X-RAY
 2020-05-13 ASP A:39 A:304 90.0 0.6 S -107.8 100.4 90.0 0.6 0.0 HOH
 1.912
 H
 O
6u41 1 P21579 99.34 3e-94 X-RAY
 2020-05-13 GLY A:39 A:304 61.0 0.813 S 72.2 176.3 61.0 0.813 0.0 HOH
 4.018
 HA3
 O
5vff 1 P46096 99.34 5e-94 X-RAY
 2018-04-11 ASP A:33 A:303 109.0 0.727 -132.3 158.3 109.0 0.727 0.0 PB
HOH
 4.366
2.632
 OD1
OD1
 PB
O
5vfg 1 P46096 99.34 5e-94 X-RAY
 2018-04-11 ASP A:33 A:303 31.0 0.207 S -107.7 120.9 31.0 0.207 0.0 PB
HOH
 2.599
3.948
 OD1
OD2
 PB
O
2n1t 5 P21579 100.0 3e-93 NMR
 2015-06-03 ASP E:41 E:303 83.0 0.553 S -68.1 147.5 83.0 0.553 0.0
5ccj 1 P21707 96.69 7e-91 X-RAY
 2015-08-12 ASP A:34 A:303 46.0 0.307 S -122.5 158.9 46.0 0.307 0.0 SO4
HOH
 7.734
2.182
 N
OD2
 O3
O
ASP B:34 B:303 77.0 0.513 S -117.6 104.3 NA NA NA
ASP C:34 C:303 62.0 0.413 S -130.9 80.2 NA NA NA
ASP D:34 D:303 70.0 0.467 S -110.1 85.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p21579-f1 1 P21579 100.0 0.0 ASP A:304 A:304 35.0 0.233 S -76.2 132.5