Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 55890907 . T A CCDS9724.1:NM_199047.2:c.1021Atc>Ttc_NP_950248.1:p.341I>F Homo sapiens TATA-box binding protein like 2 (TBPL2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5fur 1 P20226 85.12 2e-126 EM
 2016-04-06 ILE A:304 A:304 0.0 0.0 E -113.2 130.8 0.0 0.0 0.0 DA
DT
DA
DT
DA
DG
 8.770
8.742
10.000
7.323
7.116
9.967
 N
N
N
C
C
O
 N3
O4'
N3
O3'
C5'
OP1
5iy6 16 P20226 85.12 2e-126 EM
 2016-05-18 ILE P:304 P:304 1.0 0.006 E -114.1 126.3 1.0 0.006 0.0 DA
DT
DA
DA
DT
DA
DG
 9.941
8.979
9.816
8.974
7.107
6.855
8.769
 N
N
N
N
C
C
O
 C2
O4'
C5'
N3
O3'
C5'
OP1
5iy7 16 P20226 85.12 2e-126 EM
 2016-05-18 ILE P:304 P:304 3.0 0.017 E -115.5 127.5 3.0 0.017 0.0 DA
DT
DA
DT
DA
 9.052
9.017
9.330
7.639
7.402
 N
N
N
C
C
 C2
O2
C2
O3'
C5'
5iy8 16 P20226 85.12 2e-126 EM
 2016-05-18 ILE P:304 P:304 1.0 0.006 E -110.6 136.8 1.0 0.006 0.0 DA
DT
DA
DT
DA
 9.389
9.227
9.574
7.465
7.540
 N
N
N
N
O
 C2
O4'
C2
O2
C5'
5iy9 16 P20226 85.12 2e-126 EM
 2016-05-18 ILE P:304 P:304 1.0 0.006 E -111.1 128.7 1.0 0.006 0.0 DA
DT
DA
DT
DA
 9.387
9.313
9.397
7.733
8.014
 N
N
N
N
C
 N3
C5'
C2
O2
C5'
5iya 16 P20226 85.12 2e-126 EM
 2016-05-18 ILE P:304 P:304 0.0 0.0 E -114.1 126.4 0.0 0.0 0.0 DA
DT
DA
DA
DT
DA
DG
 9.793
9.052
9.957
9.136
7.318
6.931
8.998
 N
N
N
N
C
C
O
 C2
O2
C5'
N3
O3'
C5'
OP1
5iyb 16 P20226 85.12 2e-126 EM
 2016-05-18 ILE P:304 P:304 3.0 0.017 E -115.5 127.6 3.0 0.017 0.0 DA
DT
DA
DT
DA
 9.052
9.016
9.329
7.638
7.402
 N
N
N
C
C
 C2
O2
C2
O3'
C5'
5iyc 16 P20226 85.12 2e-126 EM
 2016-05-18 ILE P:304 P:304 1.0 0.006 E -110.6 136.9 1.0 0.006 0.0 DA
DT
DA
DT
DA
 9.389
9.227
9.574
7.465
7.540
 N
N
N
N
O
 C2
O4'
C2
O2
C5'
5iyd 16 P20226 85.12 2e-126 EM
 2016-05-18 ILE P:304 P:304 0.0 0.0 E -111.1 128.8 0.0 0.0 0.0 DA
DT
DA
DT
DA
 9.386
9.313
9.396
7.732
8.014
 N
N
N
N
C
 N3
C5'
C2
O2
C5'
6mzd 11 P20226 85.12 2e-126 EM
 2018-11-28 ILE K:304 T:304 0.0 0.0 E -113.4 133.2 0.0 0.0 0.0
6mzl 15 P20226 85.12 2e-126 EM
 2018-11-28 ILE T:304 T:304 0.0 0.0 E -113.4 133.2 0.0 0.0 0.0
6mzm 12 P20226 85.12 2e-126 EM
 2018-11-28 ILE L:304 T:304 0.0 0.0 E -113.2 124.0 0.0 0.0 0.0 DA
DT
DA
DA
DT
 9.399
7.996
8.134
8.836
8.840
 N
N
C
N
N
 C2
O2
OP1
N3
O4'
6o9l 16 P20226 85.12 2e-126 EM
 2019-05-29 ILE P:304 P:304 1.0 0.006 E -87.2 124.9 1.0 0.006 0.0 DT
DA
DT
DA
 9.748
9.637
8.462
8.671
 N
N
C
C
 O2
C2
O4'
C5'
7edx 12 P20226 85.12 2e-126 EM
 2021-05-05 ILE L:304 P:304 0.0 0.0 E -111.4 117.4 0.0 0.0 0.0 DA
DT
DA
DT
DA
DG
 9.145
9.659
9.925
7.370
6.886
9.954
 N
N
N
C
C
O
 N3
O4'
N3
C2'
C5'
C5'
7eg7 12 P20226 85.12 2e-126 EM
 2021-05-05 ILE L:304 P:304 0.0 0.0 E -111.3 117.5 0.0 0.0 0.0 DT
DT
DA
 9.088
9.270
9.250
 N
C
C
 O4'
C4'
C5'
7eg8 12 P20226 85.12 2e-126 EM
 2021-05-05 ILE L:304 P:304 0.0 0.0 E -111.4 117.4 0.0 0.0 0.0 DT
DA
DT
DA
DA
 9.363
9.573
9.621
7.538
7.454
 N
N
N
C
C
 O2
OP1
O2
C2'
O4'
7eg9 12 P20226 85.12 2e-126 EM
 2021-05-05 ILE L:304 P:304 0.0 0.0 E -106.9 127.8 0.0 0.0 0.0 DA
DT
DA
DT
DA
 7.741
8.145
7.013
6.292
7.926
 O
N
N
C
C
 C2
O2
N3
C4'
OP1
7ega 12 P20226 85.12 2e-126 EM
 2021-05-05 ILE L:304 P:304 0.0 0.0 E -112.7 141.8 0.0 0.0 0.0 DT
DA
DT
DA
DA
 9.669
9.806
9.587
7.773
7.674
 N
N
N
C
O
 O2
C5'
O2
C2'
O4'
7egb 22 P20226 85.12 2e-126 EM
 2021-05-05 ILE V:304 P:304 0.0 0.0 E -105.9 122.2 0.0 0.0 0.0 DA
DT
DT
DA
DG
 9.234
9.382
7.456
8.636
9.854
 N
N
C
C
O
 C2
O4'
C2'
O5'
OP1
7egc 22 P20226 85.12 2e-126 EM
 2021-05-12 ILE V:304 P:304 0.0 0.0 E -111.3 117.4 0.0 0.0 0.0 DA
DT
DT
DA
 9.101
8.712
7.104
8.157
 N
N
C
C
 C2
O2
C2'
O5'
7egd 12 P20226 85.12 2e-126 EM
 2021-05-12 ILE L:304 P:304 1.0 0.006 E -105.9 122.2 1.0 0.006 0.0 DA
DA
DT
DA
 9.721
9.772
8.197
6.339
 N
N
N
C
 OP1
O3'
C5'
OP1
7ege 11 P20226 85.12 2e-126 EM
 2021-05-12 ILE K:304 P:304 1.0 0.006 E -105.9 122.2 1.0 0.006 0.0
7egf 1 P20226 85.12 2e-126 EM
 2021-05-05 ILE A:304 P:304 1.0 0.006 E -105.9 122.2 1.0 0.006 0.0
7egi 12 P20226 85.12 2e-126 EM
 2021-05-12 ILE L:304 P:304 0.0 0.0 E -106.0 122.2 0.0 0.0 0.0
7egj 12 P20226 85.12 2e-126 EM
 2021-05-12 ILE L:304 P:304 1.0 0.006 E -105.9 122.2 1.0 0.006 0.0 DT
 8.132
 N
 OP1
7ena 5 P20226 85.12 2e-126 EM
 2021-05-26 ILE E:304 DP:304 9.0 0.051 E -101.4 118.5 9.0 0.051 0.0 DA
DT
DT
DA
DG
 9.125
8.236
7.276
7.062
8.539
 N
N
C
C
O
 C2
O2
O3'
O5'
OP1
7enc 49 P20226 85.12 2e-126 EM
 2021-05-26 ILE CB:304 DP:304 0.0 0.0 E -114.5 133.5 0.0 0.0 0.0 DA
DT
DT
DA
 9.312
9.023
7.732
7.577
 N
N
C
C
 C2
O2
C2'
O5'
7lbm 20 P20226 85.12 2e-126 EM
 2021-03-24 ILE T:304 P:304 0.0 0.0 E -93.2 125.2 0.0 0.0 0.0 DT
DA
DT
DA
DG
 9.792
9.651
8.388
7.468
9.427
 N
N
C
C
O
 O2
C2
C4'
C5'
OP1
7nvr 25 P20226 85.12 2e-126 EM
 2021-05-05 ILE Y:304 O:304 0.0 0.0 E -103.3 136.0 0.0 0.0 0.0 DA
DT
DA
DT
DA
DG
 8.971
8.995
9.607
7.457
7.428
9.823
 N
N
N
C
C
O
 C2
O2
C2
C2'
C5'
C5'
7nvs 15 P20226 85.12 2e-126 EM
 2021-05-05 ILE O:304 O:304 0.0 0.0 E -99.0 133.2 0.0 0.0 0.0 DA
DT
DA
DT
DA
 8.995
9.016
9.726
7.670
7.578
 N
N
N
N
C
 C2
O4'
C2
O2
C5'
7nvt 15 P20226 85.12 2e-126 EM
 2021-05-05 ILE O:304 O:304 0.0 0.0 E -97.0 132.9 0.0 0.0 0.0 DA
DT
DA
DT
DA
 9.235
8.712
9.807
7.952
7.686
 N
N
N
N
C
 C2
O4'
C2
O2
C5'
7nvu 15 P20226 85.12 2e-126 EM
 2021-05-05 ILE O:304 O:304 0.0 0.0 E -98.3 134.3 0.0 0.0 0.0 DA
DT
DT
DA
 9.400
8.852
7.443
7.407
 N
N
C
C
 N3
O4'
C2'
C5'
7nvy 23 P20226 85.12 2e-126 EM
 2021-05-05 ILE W:304 O:304 0.0 0.0 E -104.0 135.4 0.0 0.0 0.0 DA
DT
DA
DT
DA
DG
 8.885
8.910
9.584
7.550
7.439
9.891
 N
N
N
N
C
O
 C2
O4'
C2
O2
C5'
C5'
7nvz 23 P20226 85.12 2e-126 EM
 2021-05-05 ILE W:304 O:304 0.0 0.0 E -101.4 134.6 0.0 0.0 0.0 DA
DT
DA
DT
DA
DG
 9.169
8.694
9.681
7.854
7.561
9.996
 N
N
N
N
C
O
 C2
O4'
C2
O2
C5'
C5'
7nw0 23 P20226 85.12 2e-126 EM
 2021-05-05 ILE W:304 O:304 0.0 0.0 E -99.6 134.2 0.0 0.0 0.0 DA
DT
DT
DA
 9.393
8.777
7.372
7.378
 N
N
C
C
 N3
O4'
C2'
C5'
1jfi 5 P20226 92.86 8e-123 X-RAY
 2001-07-11 ILE E:150 C:504 0.0 0.0 E -109.3 129.5 0.0 0.0 0.0 DA
DT
DA
DT
DA
DG
HOH
 8.695
8.717
9.868
7.356
7.088
9.897
7.288
 N
N
N
C
C
O
O
 N3
O4'
N3
O3'
C5'
O5'
O
1tgh 2 P20226 92.86 1e-122 X-RAY
 1996-08-01 ILE C:150 A:300 0.0 0.0 E -100.7 132.8 0.0 0.0 0.0 DA
DT
DA
DT
DA
DC
 9.096
8.316
9.853
7.384
7.194
9.572
 N
H
N
C
C
O
 C2
O4'
N3
O3'
C5'
OP1
1nvp 3 P20226 94.38 1e-122 X-RAY
 2003-10-21 ILE C:146 A:304 0.0 0.0 E -113.9 130.6 0.0 0.0 0.0 DA
DT
DT
DA
HOH
 8.840
8.772
7.473
7.222
5.101
 N
N
C
C
O
 N3
O4'
O3'
C5'
O
1c9b 4 P20226 94.38 2e-122 X-RAY
 2000-01-10 ILE L:147 B:304 0.0 0.0 E -111.5 130.3 0.0 0.0 0.0 DA
DT
DT
DA
HOH
 8.992
8.801
7.408
7.247
4.633
 N
N
C
C
O
 N3
O4'
O3'
C5'
O
ILE N:147 F:304 0.0 0.0 E -113.0 131.2 NA NA NA
ILE P:147 J:304 0.0 0.0 E -113.8 129.0 NA NA NA
ILE R:147 N:304 0.0 0.0 E -113.8 130.1 NA NA NA
ILE T:147 R:304 0.0 0.0 E -118.1 130.5 NA NA NA
5n9g 2 P20226 94.38 2e-122 X-RAY
 2017-06-14 ILE B:165 B:304 0.0 0.0 E -105.4 126.3 0.0 0.0 0.0 DT
A
A
DT
A
HOH
 9.986
7.412
7.419
8.498
8.869
7.272
 N
C
C
N
N
O
 O2
C2'
C5'
O2
O4'
O
ILE G:165 G:304 0.0 0.0 E -104.3 126.1 NA NA NA
4roc 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 ILE B:148 B:304 0.0 0.0 E -109.2 127.2 0.0 0.0 0.0 DT
DA
DA
DA
HOH
 8.480
8.750
7.453
7.307
5.053
 N
N
C
C
O
 O2
O4'
C2'
C5'
O
4rod 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 ILE B:148 B:304 0.0 0.0 E -106.1 126.1 0.0 0.0 0.0 DT
DT
DA
DG
HOH
 8.830
9.005
7.453
7.359
5.095
 N
N
C
C
O
 O2
O4'
C2'
C5'
O
4roe 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 ILE B:148 B:304 0.0 0.0 E -111.3 122.7 0.0 0.0 0.0 DT
DT
DA
DG
HOH
 8.560
8.893
7.414
7.224
4.879
 N
N
C
C
O
 O2
O4'
C2'
C5'
O
1cdw 3 P20226 93.82 2e-121 X-RAY
 1996-12-23 ILE C:146 A:300 0.0 0.0 E -106.3 124.9 0.0 0.0 0.0 DA
DT
DT
DA
DG
HOH
 8.917
9.017
7.463
7.227
7.933
5.037
 N
N
N
C
O
O
 C2
O4'
O2
C5'
OP1
O
1vtl 3 P28147 80.9 2e-104 X-RAY
 2011-07-13 ILE E:152 E:164 0.0 0.0 E -108.5 128.4 0.0 0.0 0.0 DA
DT
DT
DA
DG
 8.791
8.607
7.499
7.229
8.919
 H
H
N
C
O
 N3
O4'
O2
C5'
OP1
ILE F:152 F:164 0.0 0.0 E -114.4 130.0 NA NA NA
1vto 3 P28147 80.9 3e-104 X-RAY
 2011-07-13 ILE E:154 A:164 0.0 0.0 E -106.6 127.4 0.0 0.0 0.0 DA
DT
DT
DA
DG
HOH
 8.813
8.630
7.586
7.200
9.677
4.185
 H
H
N
C
O
O
 N3
O4'
O2
C5'
OP1
H1
ILE F:154 B:1164 0.0 0.0 E -109.4 128.1 NA NA NA
1qn3 1 P28147 80.9 3e-104 X-RAY
 2000-02-06 ILE A:164 A:164 0.0 0.0 E -107.8 126.4 0.0 0.0 0.0 DA
DT
DT
DA
DG
HOH
 9.055
8.888
7.658
7.258
9.444
4.715
 N
N
C
C
O
O
 N3
O4'
C2'
C5'
OP1
O
ILE B:164 B:164 0.0 0.0 E -112.0 127.6 NA NA NA
1qn4 1 P28147 80.9 3e-104 X-RAY
 2000-02-06 ILE A:164 A:164 0.0 0.0 E -109.1 123.2 0.0 0.0 0.0 DA
DT
DT
DA
DG
HOH
 9.011
8.995
7.583
7.320
9.601
4.830
 N
N
N
C
O
O
 C2
O4'
O2
C5'
OP1
O
ILE B:164 B:164 0.0 0.0 E -107.5 128.9 NA NA NA
1qn5 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ILE A:164 A:164 0.0 0.0 E -109.4 123.5 0.0 0.0 0.0 DA
DT
DT
DA
DG
HOH
 8.936
8.942
7.570
7.320
9.276
4.752
 N
N
C
C
O
O
 N3
O4'
C2'
C5'
OP1
O
ILE B:164 B:164 0.0 0.0 E -105.2 128.2 NA NA NA
1qn6 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ILE A:164 A:164 0.0 0.0 E -108.4 123.6 0.0 0.0 0.0 DA
DT
DT
DA
DG
HOH
 8.997
9.055
7.493
7.233
9.654
4.711
 N
N
C
C
O
O
 C2
O4'
C2'
C5'
OP1
O
ILE B:164 B:164 0.0 0.0 E -108.8 130.8 NA NA NA
1qn7 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ILE A:164 A:164 0.0 0.0 E -103.2 127.3 0.0 0.0 0.0 DA
DT
DT
DA
DG
HOH
 8.982
8.884
7.484
7.219
9.504
4.538
 N
N
C
C
O
O
 N3
O4'
C2'
C5'
OP1
O
ILE B:164 B:164 0.0 0.0 E -107.3 132.7 NA NA NA
1qn8 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ILE A:164 A:164 0.0 0.0 E -107.6 123.5 0.0 0.0 0.0 DA
DT
DT
DA
DG
HOH
 8.966
9.006
7.577
7.337
8.399
4.760
 N
N
C
C
O
O
 C2
O4'
O3'
C5'
OP1
O
ILE B:164 B:164 0.0 0.0 E -109.9 126.8 NA NA NA
1qn9 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ILE A:164 A:164 0.0 0.0 E -112.4 124.9 0.0 0.0 0.0 DA
DC
DG
DT
DA
DG
HOH
 8.798
9.209
9.693
7.473
7.191
9.493
4.680
 N
N
N
C
C
O
O
 N3
O4'
N2
C2'
C5'
OP1
O
ILE B:164 B:164 0.0 0.0 E -104.5 133.6 NA NA NA
1qna 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ILE A:164 A:164 0.0 0.0 E -104.8 121.6 0.0 0.0 0.0 DT
DT
DA
DA
DG
HOH
 8.644
8.859
7.468
7.076
9.385
4.817
 N
N
C
C
O
O
 O2
O4'
C2'
C5'
OP1
O
ILE B:164 B:164 0.0 0.0 E -105.7 126.3 NA NA NA
1qnb 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ILE A:164 A:164 0.0 0.0 E -111.5 125.1 0.0 0.0 0.0 DA
DT
DT
DA
DG
HOH
 8.963
9.001
7.542
7.250
9.397
4.574
 N
N
N
C
O
O
 C2
O4'
O2
C5'
OP1
O
ILE B:164 B:164 0.0 0.0 E -110.3 132.6 NA NA NA
1qnc 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ILE A:164 A:164 0.0 0.0 E -111.4 124.0 0.0 0.0 0.0 DA
DT
DT
DT
DG
HOH
 8.936
9.013
7.650
7.073
9.108
4.562
 N
N
C
C
O
O
 C2
O4'
O3'
C5'
OP1
O
ILE B:164 B:164 0.0 0.0 E -104.8 127.4 NA NA NA
1qne 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ILE A:164 A:164 0.0 0.0 E -108.3 127.9 0.0 0.0 0.0 DA
DT
DT
DA
DG
HOH
 8.954
8.947
7.543
7.205
9.548
4.701
 N
N
N
C
O
O
 N3
O4'
O2
C5'
OP1
O
ILE B:164 B:164 0.0 0.0 E -109.2 129.0 NA NA NA
1vok 1 P28147 80.9 3e-104 X-RAY
 1996-11-08 ILE A:164 A:164 0.0 0.0 E -114.1 117.6 0.0 0.0 0.0 HOH
 4.497
 O
 O
ILE B:164 B:164 0.0 0.0 E -110.9 123.3 NA NA NA
1vol 4 P28147 80.9 3e-104 X-RAY
 1996-11-08 ILE D:164 B:164 0.0 0.0 E -68.9 147.3 0.0 0.0 0.0 DA
DT
DT
DA
 9.269
9.164
7.677
7.429
 O
N
C
C
 N3
O4'
O3'
C5'
6ueo 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 ILE A:183 A:164 0.0 0.0 E -113.2 130.2 0.0 0.0 0.0 DA
DT
DT
DA
DG
HOH
 8.803
8.815
7.377
7.322
9.932
4.814
 N
N
N
C
O
O
 N3
O4'
O2
C5'
OP1
O
ILE D:183 D:164 0.0 0.0 E -116.0 128.0 NA NA NA
ILE G:183 G:164 0.0 0.0 E -117.2 129.2 NA NA NA
ILE J:183 J:164 0.0 0.0 E -115.9 130.2 NA NA NA
6uep 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 ILE A:183 B:164 0.0 0.0 E -117.4 128.0 0.0 0.0 0.0 DA
DT
DT
DA
DG
HOH
 8.689
8.832
7.397
7.234
9.516
4.693
 N
N
C
C
O
O
 N3
O4'
C2'
C5'
OP1
O
ILE D:183 A:164 0.0 0.0 E -121.7 127.5 NA NA NA
6ueq 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 ILE A:183 B:164 0.0 0.0 E -113.6 132.0 0.0 0.0 0.0 DA
DT
DT
DA
DG
HOH
 9.032
9.015
7.514
7.177
8.986
4.715
 N
N
C
C
O
O
 C2
O4'
C2'
C5'
OP1
O
6uer 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 ILE A:183 A:164 0.0 0.0 E -106.4 124.5 0.0 0.0 0.0 DA
DT
DT
DA
DG
 8.743
8.789
7.466
7.340
9.969
 N
N
C
C
O
 N3
O4'
C2'
C5'
OP1
ILE D:183 B:164 0.0 0.0 E -113.5 137.3 NA NA NA
6njq 1 P28147 80.9 8e-104 X-RAY
 2019-10-30 ILE A:184 B:164 0.0 0.0 E -104.5 138.8 0.0 0.0 0.0 DA
DT
DT
DA
DG
 8.934
8.977
7.458
7.507
8.853
 N
N
N
C
O
 N3
O4'
O2
C5'
OP1
ILE D:184 A:164 0.0 0.0 E -102.5 126.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6sj96-f1 1 Q6SJ96 100.0 0.0 ILE A:341 A:341 0.0 0.0 E -111.2 120.7
af-p20226-f1 1 P20226 85.12 8e-127 ILE A:304 A:304 0.0 0.0 E -108.7 124.5