Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 55895672 . G A CCDS9724.1:NM_199047.2:c.809gCa>gTa_NP_950248.1:p.270A>V Homo sapiens TATA-box binding protein like 2 (TBPL2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5fur 1 P20226 85.12 2e-126 EM
 2016-04-06 ALA A:233 A:233 0.0 0.0 H -50.7 -51.6 0.0 0.0 0.0
5iy6 16 P20226 85.12 2e-126 EM
 2016-05-18 ALA P:233 P:233 0.0 0.0 H -60.3 -49.9 0.0 0.0 0.0
5iy7 16 P20226 85.12 2e-126 EM
 2016-05-18 ALA P:233 P:233 0.0 0.0 H -59.8 -48.4 0.0 0.0 0.0
5iy8 16 P20226 85.12 2e-126 EM
 2016-05-18 ALA P:233 P:233 0.0 0.0 H -63.0 -46.5 0.0 0.0 0.0
5iy9 16 P20226 85.12 2e-126 EM
 2016-05-18 ALA P:233 P:233 0.0 0.0 H -63.5 -49.1 0.0 0.0 0.0
5iya 16 P20226 85.12 2e-126 EM
 2016-05-18 ALA P:233 P:233 2.0 0.017 H -60.3 -49.9 2.0 0.017 0.0
5iyb 16 P20226 85.12 2e-126 EM
 2016-05-18 ALA P:233 P:233 0.0 0.0 H -59.8 -48.4 0.0 0.0 0.0
5iyc 16 P20226 85.12 2e-126 EM
 2016-05-18 ALA P:233 P:233 0.0 0.0 H -63.0 -46.5 0.0 0.0 0.0
5iyd 16 P20226 85.12 2e-126 EM
 2016-05-18 ALA P:233 P:233 2.0 0.017 H -63.6 -49.1 2.0 0.017 0.0
6mzd 11 P20226 85.12 2e-126 EM
 2018-11-28 ALA K:233 T:233 0.0 0.0 H -61.6 -46.3 0.0 0.0 0.0
6mzl 15 P20226 85.12 2e-126 EM
 2018-11-28 ALA T:233 T:233 0.0 0.0 H -61.6 -46.3 0.0 0.0 0.0
6mzm 12 P20226 85.12 2e-126 EM
 2018-11-28 ALA L:233 T:233 0.0 0.0 H -61.4 -47.2 0.0 0.0 0.0
6o9l 16 P20226 85.12 2e-126 EM
 2019-05-29 ALA P:233 P:233 0.0 0.0 H -71.8 -32.5 0.0 0.0 0.0
7edx 12 P20226 85.12 2e-126 EM
 2021-05-05 ALA L:233 P:233 0.0 0.0 H -65.3 -41.2 0.0 0.0 0.0
7eg7 12 P20226 85.12 2e-126 EM
 2021-05-05 ALA L:233 P:233 0.0 0.0 H -65.4 -41.1 0.0 0.0 0.0
7eg8 12 P20226 85.12 2e-126 EM
 2021-05-05 ALA L:233 P:233 0.0 0.0 H -65.4 -41.1 0.0 0.0 0.0
7eg9 12 P20226 85.12 2e-126 EM
 2021-05-05 ALA L:233 P:233 1.0 0.009 H -65.4 -41.2 1.0 0.009 0.0
7ega 12 P20226 85.12 2e-126 EM
 2021-05-05 ALA L:233 P:233 1.0 0.009 H -65.4 -41.1 1.0 0.009 0.0
7egb 22 P20226 85.12 2e-126 EM
 2021-05-05 ALA V:233 P:233 2.0 0.017 H -68.9 -34.8 2.0 0.017 0.0
7egc 22 P20226 85.12 2e-126 EM
 2021-05-12 ALA V:233 P:233 0.0 0.0 H -62.7 -41.7 0.0 0.0 0.0
7egd 12 P20226 85.12 2e-126 EM
 2021-05-12 ALA L:233 P:233 0.0 0.0 H -68.9 -34.9 0.0 0.0 0.0
7ege 11 P20226 85.12 2e-126 EM
 2021-05-12 ALA K:233 P:233 0.0 0.0 H -69.0 -34.9 0.0 0.0 0.0
7egf 1 P20226 85.12 2e-126 EM
 2021-05-05 ALA A:233 P:233 0.0 0.0 H -69.0 -34.9 0.0 0.0 0.0
7egi 12 P20226 85.12 2e-126 EM
 2021-05-12 ALA L:233 P:233 0.0 0.0 H -69.0 -34.9 0.0 0.0 0.0
7egj 12 P20226 85.12 2e-126 EM
 2021-05-12 ALA L:233 P:233 0.0 0.0 H -68.9 -34.9 0.0 0.0 0.0
7ena 5 P20226 85.12 2e-126 EM
 2021-05-26 ALA E:233 DP:233 0.0 0.0 H -63.9 -42.8 0.0 0.0 0.0
7enc 49 P20226 85.12 2e-126 EM
 2021-05-26 ALA CB:233 DP:233 0.0 0.0 H -63.7 -42.2 0.0 0.0 0.0
7lbm 20 P20226 85.12 2e-126 EM
 2021-03-24 ALA T:233 P:233 0.0 0.0 H -72.3 -34.8 0.0 0.0 0.0 DT
 9.995
 CB
 OP1
7nvr 25 P20226 85.12 2e-126 EM
 2021-05-05 ALA Y:233 O:233 0.0 0.0 H -65.4 -41.3 0.0 0.0 0.0
7nvs 15 P20226 85.12 2e-126 EM
 2021-05-05 ALA O:233 O:233 0.0 0.0 H -63.1 -42.9 0.0 0.0 0.0
7nvt 15 P20226 85.12 2e-126 EM
 2021-05-05 ALA O:233 O:233 0.0 0.0 H -62.9 -43.0 0.0 0.0 0.0
7nvu 15 P20226 85.12 2e-126 EM
 2021-05-05 ALA O:233 O:233 0.0 0.0 H -63.4 -42.7 0.0 0.0 0.0
7nvy 23 P20226 85.12 2e-126 EM
 2021-05-05 ALA W:233 O:233 0.0 0.0 H -65.0 -41.2 0.0 0.0 0.0
7nvz 23 P20226 85.12 2e-126 EM
 2021-05-05 ALA W:233 O:233 0.0 0.0 H -65.1 -40.7 0.0 0.0 0.0
7nw0 23 P20226 85.12 2e-126 EM
 2021-05-05 ALA W:233 O:233 0.0 0.0 H -63.3 -42.6 0.0 0.0 0.0
1jfi 5 P20226 92.86 8e-123 X-RAY
 2001-07-11 ALA E:79 C:433 0.0 0.0 H -51.7 -44.2 0.0 0.0 0.0 HOH
 5.556
 CB
 O
1tgh 2 P20226 92.86 1e-122 X-RAY
 1996-08-01 ALA C:79 A:229 0.0 0.0 H -49.8 -36.6 0.0 0.0 0.0 HOH
 7.860
 H
 H2
1nvp 3 P20226 94.38 1e-122 X-RAY
 2003-10-21 ALA C:75 A:233 0.0 0.0 H -50.7 -51.6 0.0 0.0 0.0 HOH
 5.503
 CB
 O
1c9b 4 P20226 94.38 2e-122 X-RAY
 2000-01-10 ALA L:76 B:233 0.0 0.0 H -59.0 -46.0 0.0 0.0 0.0 HOH
 5.829
 CB
 O
ALA N:76 F:233 0.0 0.0 H -55.8 -48.6 NA NA NA
ALA P:76 J:233 0.0 0.0 H -57.0 -46.4 NA NA NA
ALA R:76 N:233 0.0 0.0 H -53.3 -47.4 NA NA NA
ALA T:76 R:233 0.0 0.0 H -56.6 -46.3 NA NA NA
5n9g 2 P20226 94.38 2e-122 X-RAY
 2017-06-14 ALA B:94 B:233 0.0 0.0 H -67.8 -46.4 0.0 0.0 0.0
ALA G:94 G:233 0.0 0.0 H -67.8 -48.2 NA NA NA
4roc 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 ALA B:77 B:233 0.0 0.0 H -68.8 -44.3 0.0 0.0 0.0 HOH
 5.922
 CB
 O
4rod 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 ALA B:77 B:233 0.0 0.0 H -64.2 -46.0 0.0 0.0 0.0 HOH
 7.731
 N
 O
4roe 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 ALA B:77 B:233 0.0 0.0 H -62.2 -52.2 0.0 0.0 0.0 HOH
 5.692
 CB
 O
1cdw 3 P20226 93.82 2e-121 X-RAY
 1996-12-23 ALA C:75 A:229 0.0 0.0 H -62.2 -44.8 0.0 0.0 0.0 HOH
 5.737
 CB
 O
1vtl 3 P28147 80.9 2e-104 X-RAY
 2011-07-13 ALA E:81 E:93 0.0 0.0 H -60.6 -43.1 0.0 0.0 0.0
ALA F:81 F:93 0.0 0.0 H -55.6 -47.9 NA NA NA
1vto 3 P28147 80.9 3e-104 X-RAY
 2011-07-13 ALA E:83 A:93 0.0 0.0 H -69.3 -44.6 0.0 0.0 0.0 HOH
 5.508
 N
 O
ALA F:83 B:1093 0.0 0.0 H -58.9 -41.3 NA NA NA
1qn3 1 P28147 80.9 3e-104 X-RAY
 2000-02-06 ALA A:93 A:93 0.0 0.0 H -56.5 -49.8 0.0 0.0 0.0 HOH
 5.659
 CB
 O
ALA B:93 B:93 0.0 0.0 H -62.0 -44.3 NA NA NA
1qn4 1 P28147 80.9 3e-104 X-RAY
 2000-02-06 ALA A:93 A:93 0.0 0.0 H -59.0 -49.1 0.0 0.0 0.0 HOH
 5.742
 CB
 O
ALA B:93 B:93 0.0 0.0 H -58.9 -47.1 NA NA NA
1qn5 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ALA A:93 A:93 0.0 0.0 H -68.2 -41.2 0.0 0.0 0.0 HOH
 5.022
 N
 O
ALA B:93 B:93 0.0 0.0 H -59.9 -47.7 NA NA NA
1qn6 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ALA A:93 A:93 0.0 0.0 H -61.3 -47.5 0.0 0.0 0.0 HOH
 5.558
 CB
 O
ALA B:93 B:93 0.0 0.0 H -63.9 -46.7 NA NA NA
1qn7 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ALA A:93 A:93 0.0 0.0 H -64.5 -38.5 0.0 0.0 0.0 HOH
 5.662
 CB
 O
ALA B:93 B:93 0.0 0.0 H -60.9 -43.3 NA NA NA
1qn8 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ALA A:93 A:93 0.0 0.0 H -63.5 -46.9 0.0 0.0 0.0 HOH
 5.685
 CB
 O
ALA B:93 B:93 0.0 0.0 H -65.3 -43.2 NA NA NA
1qn9 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ALA A:93 A:93 0.0 0.0 H -64.9 -39.4 0.0 0.0 0.0 HOH
 5.710
 CB
 O
ALA B:93 B:93 0.0 0.0 H -59.2 -45.5 NA NA NA
1qna 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ALA A:93 A:93 0.0 0.0 H -66.4 -46.0 0.0 0.0 0.0 HOH
 5.485
 N
 O
ALA B:93 B:93 0.0 0.0 H -60.4 -48.7 NA NA NA
1qnb 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ALA A:93 A:93 0.0 0.0 H -65.9 -43.1 0.0 0.0 0.0 HOH
 5.652
 CB
 O
ALA B:93 B:93 0.0 0.0 H -62.2 -40.4 NA NA NA
1qnc 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ALA A:93 A:93 0.0 0.0 H -61.3 -48.0 0.0 0.0 0.0 HOH
 5.511
 CB
 O
ALA B:93 B:93 0.0 0.0 H -59.3 -53.5 NA NA NA
1qne 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 ALA A:93 A:93 0.0 0.0 H -67.5 -46.0 0.0 0.0 0.0 HOH
 5.559
 CB
 O
ALA B:93 B:93 0.0 0.0 H -58.6 -42.0 NA NA NA
1vok 1 P28147 80.9 3e-104 X-RAY
 1996-11-08 ALA A:93 A:93 0.0 0.0 H -67.6 -40.2 0.0 0.0 0.0 HOH
 4.958
 N
 O
ALA B:93 B:93 0.0 0.0 H -62.6 -42.2 NA NA NA
1vol 4 P28147 80.9 3e-104 X-RAY
 1996-11-08 ALA D:93 B:93 0.0 0.0 H -45.9 -39.8 0.0 0.0 0.0
6ueo 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 ALA A:112 A:93 0.0 0.0 H -68.7 -45.2 0.0 0.0 0.0 HOH
 5.617
 CB
 O
ALA D:112 D:93 0.0 0.0 H -62.0 -43.8 NA NA NA
ALA G:112 G:93 0.0 0.0 H -63.8 -46.2 NA NA NA
ALA J:112 J:93 0.0 0.0 H -66.4 -41.5 NA NA NA
6uep 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 ALA A:112 B:93 0.0 0.0 H -64.6 -43.0 0.0 0.0 0.0 HOH
 5.655
 CB
 O
ALA D:112 A:93 0.0 0.0 H -59.8 -41.8 NA NA NA
6ueq 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 ALA A:112 B:93 0.0 0.0 H -61.4 -39.1 0.0 0.0 0.0 SO4
HOH
 8.775
5.788
 CA
CB
 O2
O
6uer 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 ALA A:112 A:93 0.0 0.0 H -67.0 -44.6 0.0 0.0 0.0 HOH
 5.858
 CB
 O
ALA D:112 B:93 0.0 0.0 H -63.1 -39.7 NA NA NA
6njq 1 P28147 80.9 8e-104 X-RAY
 2019-10-30 ALA A:113 B:93 0.0 0.0 H -59.6 -47.3 0.0 0.0 0.0
ALA D:113 A:93 0.0 0.0 H -57.2 -42.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6sj96-f1 1 Q6SJ96 100.0 0.0 ALA A:270 A:270 0.0 0.0 H -59.0 -54.3
af-p20226-f1 1 P20226 85.12 8e-127 ALA A:233 A:233 0.0 0.0 H -56.8 -52.2