Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 55895679 . G A CCDS9724.1:NM_199047.2:c.802Cga>Tga_NP_950248.1:p.268R>* Homo sapiens TATA-box binding protein like 2 (TBPL2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5fur 1 P20226 85.12 2e-126 EM
 2016-04-06 ARG A:231 A:231 95.0 0.422 H -71.1 -40.0 95.0 0.422 0.0
5iy6 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:231 P:231 99.0 0.44 H -67.2 -41.8 99.0 0.44 0.0
5iy7 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:231 P:231 103.0 0.458 H -63.3 -39.5 98.0 0.436 0.022 N:P52655:0.022
5iy8 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:231 P:231 104.0 0.462 H -69.2 -33.1 104.0 0.462 0.0
5iy9 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:231 P:231 128.0 0.569 H -67.8 -35.7 99.0 0.44 0.129 N:P52655:0.129
5iya 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:231 P:231 99.0 0.44 H -67.2 -41.8 99.0 0.44 0.0
5iyb 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:231 P:231 100.0 0.444 H -63.3 -39.5 95.0 0.422 0.022 N:P52655:0.022
5iyc 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:231 P:231 102.0 0.453 H -69.3 -33.0 102.0 0.453 0.0
5iyd 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:231 P:231 128.0 0.569 H -67.8 -35.6 99.0 0.44 0.129 N:P52655:0.129
6mzd 11 P20226 85.12 2e-126 EM
 2018-11-28 ARG K:231 T:231 98.0 0.436 H -68.5 -39.9 80.0 0.356 0.08 A:P21675:0.08
6mzl 15 P20226 85.12 2e-126 EM
 2018-11-28 ARG T:231 T:231 98.0 0.436 H -68.5 -39.9 80.0 0.356 0.08 A:P21675:0.08
6mzm 12 P20226 85.12 2e-126 EM
 2018-11-28 ARG L:231 T:231 99.0 0.44 H -69.4 -39.4 99.0 0.44 0.0
6o9l 16 P20226 85.12 2e-126 EM
 2019-05-29 ARG P:231 P:231 120.0 0.533 H -70.8 -33.8 120.0 0.533 0.0
7edx 12 P20226 85.12 2e-126 EM
 2021-05-05 ARG L:231 P:231 88.0 0.391 H -61.1 -43.5 78.0 0.347 0.044 M:P52655:0.044
7eg7 12 P20226 85.12 2e-126 EM
 2021-05-05 ARG L:231 P:231 83.0 0.369 H -61.1 -43.6 82.0 0.364 0.005 M:P52655:0.004
7eg8 12 P20226 85.12 2e-126 EM
 2021-05-05 ARG L:231 P:231 85.0 0.378 H -61.3 -43.6 85.0 0.378 0.0
7eg9 12 P20226 85.12 2e-126 EM
 2021-05-05 ARG L:231 P:231 84.0 0.373 H -61.1 -43.5 84.0 0.373 0.0
7ega 12 P20226 85.12 2e-126 EM
 2021-05-05 ARG L:231 P:231 91.0 0.404 H -61.2 -43.6 90.0 0.4 0.004 M:P52655:0.004
7egb 22 P20226 85.12 2e-126 EM
 2021-05-05 ARG V:231 P:231 94.0 0.418 H -67.1 -36.8 92.0 0.409 0.009 W:P52655:0.009
7egc 22 P20226 85.12 2e-126 EM
 2021-05-12 ARG V:231 P:231 85.0 0.378 H -61.1 -48.0 77.0 0.342 0.036 W:P52655:0.036
7egd 12 P20226 85.12 2e-126 EM
 2021-05-12 ARG L:231 P:231 94.0 0.418 H -67.0 -36.9 94.0 0.418 0.0
7ege 11 P20226 85.12 2e-126 EM
 2021-05-12 ARG K:231 P:231 95.0 0.422 H -67.0 -36.9 95.0 0.422 0.0
7egf 1 P20226 85.12 2e-126 EM
 2021-05-05 ARG A:231 P:231 94.0 0.418 H -67.0 -36.8 94.0 0.418 0.0
7egi 12 P20226 85.12 2e-126 EM
 2021-05-12 ARG L:231 P:231 95.0 0.422 H -67.0 -36.8 95.0 0.422 0.0
7egj 12 P20226 85.12 2e-126 EM
 2021-05-12 ARG L:231 P:231 94.0 0.418 H -66.9 -36.9 94.0 0.418 0.0
7ena 5 P20226 85.12 2e-126 EM
 2021-05-26 ARG E:231 DP:231 93.0 0.413 H -64.7 -43.3 92.0 0.409 0.004 F:None:0.004
7enc 49 P20226 85.12 2e-126 EM
 2021-05-26 ARG CB:231 DP:231 91.0 0.404 H -64.6 -42.8 88.0 0.391 0.013 DB:None:0.013
7lbm 20 P20226 85.12 2e-126 EM
 2021-03-24 ARG T:231 P:231 91.0 0.404 H -62.1 -52.7 45.0 0.2 0.204 Q:P52655:0.204
7nvr 25 P20226 85.12 2e-126 EM
 2021-05-05 ARG Y:231 O:231 87.0 0.387 H -63.5 -43.7 87.0 0.387 0.0
7nvs 15 P20226 85.12 2e-126 EM
 2021-05-05 ARG O:231 O:231 77.0 0.342 H -65.1 -43.6 65.0 0.289 0.053 S:P52655:0.053
7nvt 15 P20226 85.12 2e-126 EM
 2021-05-05 ARG O:231 O:231 75.0 0.333 H -64.5 -43.0 63.0 0.28 0.053 S:P52655:0.053
7nvu 15 P20226 85.12 2e-126 EM
 2021-05-05 ARG O:231 O:231 88.0 0.391 H -64.8 -43.7 88.0 0.391 0.0
7nvy 23 P20226 85.12 2e-126 EM
 2021-05-05 ARG W:231 O:231 78.0 0.347 H -64.7 -41.4 66.0 0.293 0.054 AA:P52655:0.053
7nvz 23 P20226 85.12 2e-126 EM
 2021-05-05 ARG W:231 O:231 75.0 0.333 H -64.5 -41.0 63.0 0.28 0.053 AA:P52655:0.053
7nw0 23 P20226 85.12 2e-126 EM
 2021-05-05 ARG W:231 O:231 86.0 0.382 H -65.3 -43.7 86.0 0.382 0.0
1jfi 5 P20226 92.86 8e-123 X-RAY
 2001-07-11 ARG E:77 C:431 74.0 0.329 H -74.2 -29.4 74.0 0.329 0.0 HOH
 6.162
 N
 O
1tgh 2 P20226 92.86 1e-122 X-RAY
 1996-08-01 ARG C:77 A:227 75.0 0.333 H -55.3 -43.5 75.0 0.333 0.0 HOH
 1.991
 HH22
 O
1nvp 3 P20226 94.38 1e-122 X-RAY
 2003-10-21 ARG C:73 A:231 97.0 0.431 H -71.1 -40.0 97.0 0.431 0.0 HOH
 2.508
 NH1
 O
1c9b 4 P20226 94.38 2e-122 X-RAY
 2000-01-10 ARG L:74 B:231 114.0 0.507 H -70.5 -36.6 114.0 0.507 0.0 HOH
 2.821
 NH2
 O
ARG N:74 F:231 130.0 0.578 H -66.7 -38.5 NA NA NA
ARG P:74 J:231 79.0 0.351 H -62.5 -40.7 NA NA NA
ARG R:74 N:231 102.0 0.453 H -60.2 -41.7 NA NA NA
ARG T:74 R:231 98.0 0.436 H -68.4 -32.9 NA NA NA
5n9g 2 P20226 94.38 2e-122 X-RAY
 2017-06-14 ARG B:92 B:231 119.0 0.529 H -69.0 -45.6 70.0 0.311 0.218 A:Q9HAW0:0.218
ARG G:92 G:231 120.0 0.533 H -66.0 -45.5 NA NA NA
4roc 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 ARG B:75 B:231 123.0 0.547 H -68.6 -46.2 74.0 0.329 0.218 A:Q9HAW0:0.218
 HOH
 6.156
 N
 O
4rod 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 ARG B:75 B:231 124.0 0.551 H -69.9 -45.6 73.0 0.324 0.227 A:Q9HAW0:0.227
 HOH
 3.075
 NH1
 O
4roe 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 ARG B:75 B:231 121.0 0.538 H -67.1 -43.8 68.0 0.302 0.236 A:Q9HAW0:0.236
 HOH
 3.249
 NH2
 O
1cdw 3 P20226 93.82 2e-121 X-RAY
 1996-12-23 ARG C:73 A:227 117.0 0.52 H -66.8 -39.1 117.0 0.52 0.0 HOH
 2.704
 NH1
 O
1vtl 3 P28147 80.9 2e-104 X-RAY
 2011-07-13 LYS E:79 E:91 89.0 0.445 H -63.7 -47.6 89.0 0.445 0.0
LYS F:79 F:91 75.0 0.375 H -71.6 -35.9 NA NA NA
1vto 3 P28147 80.9 3e-104 X-RAY
 2011-07-13 LYS E:81 A:91 101.0 0.505 H -61.3 -49.4 101.0 0.505 0.0 HOH
 3.111
 CE
 H2
LYS F:81 B:1091 84.0 0.42 H -66.0 -42.4 NA NA NA
1qn3 1 P28147 80.9 3e-104 X-RAY
 2000-02-06 LYS A:91 A:91 89.0 0.445 H -73.1 -39.6 89.0 0.445 0.0 HOH
 3.215
 CE
 O
LYS B:91 B:91 88.0 0.44 H -63.7 -46.0 NA NA NA
1qn4 1 P28147 80.9 3e-104 X-RAY
 2000-02-06 LYS A:91 A:91 97.0 0.485 H -67.9 -41.3 97.0 0.485 0.0 HOH
 3.227
 CB
 O
LYS B:91 B:91 80.0 0.4 H -70.9 -39.0 NA NA NA
1qn5 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:91 A:91 83.0 0.415 H -65.0 -39.4 83.0 0.415 0.0 HOH
 3.386
 NZ
 O
LYS B:91 B:91 82.0 0.41 H -66.7 -43.6 NA NA NA
1qn6 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:91 A:91 89.0 0.445 H -69.0 -36.1 89.0 0.445 0.0 HOH
 2.906
 NZ
 O
LYS B:91 B:91 80.0 0.4 H -69.5 -43.7 NA NA NA
1qn7 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:91 A:91 87.0 0.435 H -65.9 -41.8 87.0 0.435 0.0 HOH
 5.137
 CE
 O
LYS B:91 B:91 80.0 0.4 H -70.5 -40.5 NA NA NA
1qn8 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:91 A:91 98.0 0.49 H -68.6 -33.9 98.0 0.49 0.0 HOH
 2.876
 NZ
 O
LYS B:91 B:91 86.0 0.43 H -66.8 -45.6 NA NA NA
1qn9 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:91 A:91 102.0 0.51 H -62.7 -40.2 102.0 0.51 0.0 HOH
 5.275
 CE
 O
LYS B:91 B:91 73.0 0.365 H -65.8 -37.5 NA NA NA
1qna 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:91 A:91 80.0 0.4 H -67.3 -40.8 80.0 0.4 0.0 HOH
 2.935
 NZ
 O
LYS B:91 B:91 93.0 0.465 H -66.1 -43.1 NA NA NA
1qnb 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:91 A:91 82.0 0.41 H -58.9 -44.4 82.0 0.41 0.0 HOH
 3.376
 CD
 O
LYS B:91 B:91 73.0 0.365 H -69.6 -44.6 NA NA NA
1qnc 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:91 A:91 80.0 0.4 H -66.7 -38.6 80.0 0.4 0.0 HOH
 4.846
 NZ
 O
LYS B:91 B:91 70.0 0.35 H -67.7 -42.9 NA NA NA
1qne 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:91 A:91 102.0 0.51 H -60.4 -50.3 102.0 0.51 0.0 HOH
 3.274
 CD
 O
LYS B:91 B:91 83.0 0.415 H -65.3 -43.7 NA NA NA
1vok 1 P28147 80.9 3e-104 X-RAY
 1996-11-08 LYS A:91 A:91 78.0 0.39 H -67.4 -44.6 78.0 0.39 0.0 HOH
 3.099
 NZ
 O
LYS B:91 B:91 79.0 0.395 H -63.6 -42.4 NA NA NA
1vol 4 P28147 80.9 3e-104 X-RAY
 1996-11-08 LYS D:91 B:91 81.0 0.405 H -66.1 -56.1 81.0 0.405 0.0
6ueo 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 LYS A:110 A:91 105.0 0.525 H -73.6 -43.2 105.0 0.525 0.0 HOH
 4.048
 CB
 O
LYS D:110 D:91 91.0 0.455 H -68.3 -39.7 NA NA NA
LYS G:110 G:91 90.0 0.45 H -65.9 -39.7 NA NA NA
LYS J:110 J:91 80.0 0.4 H -66.8 -40.3 NA NA NA
6uep 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 LYS A:110 B:91 87.0 0.435 H -66.8 -42.6 87.0 0.435 0.0 HOH
 3.043
 NZ
 O
LYS D:110 A:91 91.0 0.455 H -69.6 -41.4 NA NA NA
6ueq 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 LYS A:110 B:91 81.0 0.405 H -66.3 -39.3 81.0 0.405 0.0 HOH
 3.793
 CE
 O
6uer 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 LYS A:110 A:91 75.0 0.375 H -66.0 -39.6 75.0 0.375 0.0 HOH
 6.130
 N
 O
LYS D:110 B:91 67.0 0.335 H -62.8 -39.0 NA NA NA
6njq 1 P28147 80.9 8e-104 X-RAY
 2019-10-30 LYS A:111 B:91 83.0 0.415 H -59.2 -45.0 83.0 0.415 0.0
LYS D:111 A:91 77.0 0.385 H -56.6 -33.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6sj96-f1 1 Q6SJ96 100.0 0.0 ARG A:268 A:268 132.0 0.587 H -63.4 -42.0
af-p20226-f1 1 P20226 85.12 8e-127 ARG A:231 A:231 143.0 0.636 H -64.8 -44.2