Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 55900372 . T A CCDS9724.1:NM_199047.2:c.764aAg>aTg_NP_950248.1:p.255K>M Homo sapiens TATA-box binding protein like 2 (TBPL2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5fur 1 P20226 85.12 2e-126 EM
 2016-04-06 LYS A:218 A:218 126.0 0.63 E -88.1 149.9 126.0 0.63 0.0 DA
DA
DG
 6.252
3.718
3.472
 CD
CB
CG
 O3'
O3'
OP1
5iy6 16 P20226 85.12 2e-126 EM
 2016-05-18 LYS P:218 P:218 97.0 0.485 E -68.4 146.0 97.0 0.485 0.0 DA
DA
DG
DG
 8.658
4.823
3.590
9.308
 NZ
CG
NZ
N
 O3'
O3'
OP1
OP1
5iy7 16 P20226 85.12 2e-126 EM
 2016-05-18 LYS P:218 P:218 121.0 0.605 E -85.4 145.2 121.0 0.605 0.0 DA
DA
DG
DG
 6.215
3.611
3.095
9.036
 NZ
CD
NZ
NZ
 O3'
O3'
OP1
OP2
5iy8 16 P20226 85.12 2e-126 EM
 2016-05-18 LYS P:218 P:218 122.0 0.61 E -86.3 147.3 122.0 0.61 0.0 DA
DA
DG
 5.474
3.095
3.129
 NZ
NZ
CD
 O3'
O5'
OP1
5iy9 16 P20226 85.12 2e-126 EM
 2016-05-18 LYS P:218 P:218 109.0 0.545 E -82.2 147.9 109.0 0.545 0.0 DA
DA
DG
DG
 5.543
3.199
2.515
8.930
 NZ
NZ
NZ
NZ
 O3'
O5'
OP1
OP2
5iya 16 P20226 85.12 2e-126 EM
 2016-05-18 LYS P:218 P:218 97.0 0.485 E -68.3 146.0 97.0 0.485 0.0 DA
DA
DG
DG
 8.624
4.713
3.528
9.359
 NZ
CG
CG
N
 O3'
O3'
OP1
OP1
5iyb 16 P20226 85.12 2e-126 EM
 2016-05-18 LYS P:218 P:218 123.0 0.615 E -85.3 145.1 123.0 0.615 0.0 DA
DA
DG
DG
 6.215
3.611
3.095
9.036
 NZ
CD
NZ
NZ
 O3'
O3'
OP1
OP2
5iyc 16 P20226 85.12 2e-126 EM
 2016-05-18 LYS P:218 P:218 123.0 0.615 E -86.3 147.3 123.0 0.615 0.0 DA
DA
DG
 5.474
3.095
3.130
 NZ
NZ
CD
 O3'
O5'
OP1
5iyd 16 P20226 85.12 2e-126 EM
 2016-05-18 LYS P:218 P:218 108.0 0.54 E -82.2 147.9 108.0 0.54 0.0 DA
DA
DG
DG
 5.544
3.198
2.516
8.931
 NZ
NZ
NZ
NZ
 O3'
O5'
OP1
OP2
6mzd 11 P20226 85.12 2e-126 EM
 2018-11-28 LYS K:218 T:218 122.0 0.61 E -92.5 142.5 122.0 0.61 0.0
6mzl 15 P20226 85.12 2e-126 EM
 2018-11-28 LYS T:218 T:218 122.0 0.61 E -92.5 142.5 122.0 0.61 0.0
6mzm 12 P20226 85.12 2e-126 EM
 2018-11-28 LYS L:218 T:218 128.0 0.64 E -91.0 143.0 128.0 0.64 0.0 DA
DA
DG
DG
 6.071
3.562
3.359
9.926
 CD
CB
CD
CD
 O3'
O3'
OP1
OP1
6o9l 16 P20226 85.12 2e-126 EM
 2019-05-29 LYS P:218 P:218 78.0 0.39 E -73.0 135.2 78.0 0.39 0.0 DA
DA
DG
DG
 6.875
3.839
3.683
9.584
 NZ
CG
NZ
CG
 O3'
O3'
OP1
OP2
7edx 12 P20226 85.12 2e-126 EM
 2021-05-05 LYS L:218 P:218 127.0 0.635 E -98.2 131.3 127.0 0.635 0.0 DA
DA
DA
 5.496
3.623
4.110
 CD
CD
NZ
 O3'
OP1
OP1
7eg7 12 P20226 85.12 2e-126 EM
 2021-05-05 LYS L:218 P:218 126.0 0.63 E -98.2 131.3 126.0 0.63 0.0 DA
DA
DG
 7.421
5.572
5.609
 CD
CD
NZ
 O3'
C5'
OP1
7eg8 12 P20226 85.12 2e-126 EM
 2021-05-05 LYS L:218 P:218 126.0 0.63 E -98.3 131.1 126.0 0.63 0.0 DC
DA
DG
DC
 7.248
4.883
4.197
9.515
 CD
CB
CD
N
 O3'
O3'
OP1
OP1
7eg9 12 P20226 85.12 2e-126 EM
 2021-05-05 LYS L:218 P:218 83.0 0.415 E -134.3 159.7 83.0 0.415 0.0 DA
DG
DG
 4.886
3.156
5.035
 CB
CD
CE
 O3'
OP1
OP1
7ega 12 P20226 85.12 2e-126 EM
 2021-05-05 LYS L:218 P:218 124.0 0.62 E -98.3 131.2 124.0 0.62 0.0 DC
DA
DG
DC
 7.249
4.883
4.195
9.514
 CD
CD
CD
N
 O3'
OP2
OP1
OP1
7egb 22 P20226 85.12 2e-126 EM
 2021-05-05 LYS V:218 P:218 101.0 0.505 E -101.3 141.4 101.0 0.505 0.0 DA
DA
DG
DG
 6.813
3.715
3.570
9.489
 CD
CD
CG
N
 O3'
C5'
OP2
OP1
7egc 22 P20226 85.12 2e-126 EM
 2021-05-12 LYS V:218 P:218 128.0 0.64 E -98.1 131.1 128.0 0.64 0.0 DA
DA
DA
DC
 7.148
3.411
2.497
8.717
 CD
CB
CD
N
 O3'
O3'
OP2
OP1
7egd 12 P20226 85.12 2e-126 EM
 2021-05-12 LYS L:218 P:218 103.0 0.515 E -101.4 141.3 103.0 0.515 0.0 DG
 9.034
 CD
 OP1
7ege 11 P20226 85.12 2e-126 EM
 2021-05-12 LYS K:218 P:218 103.0 0.515 E -101.5 141.5 103.0 0.515 0.0
7egf 1 P20226 85.12 2e-126 EM
 2021-05-05 LYS A:218 P:218 103.0 0.515 E -101.5 141.4 103.0 0.515 0.0
7egi 12 P20226 85.12 2e-126 EM
 2021-05-12 LYS L:218 P:218 103.0 0.515 E -101.5 141.5 103.0 0.515 0.0
7egj 12 P20226 85.12 2e-126 EM
 2021-05-12 LYS L:218 P:218 103.0 0.515 E -101.4 141.3 103.0 0.515 0.0 DG
DG
 8.797
8.467
 CD
CB
 OP1
OP1
7ena 5 P20226 85.12 2e-126 EM
 2021-05-26 LYS E:218 DP:218 104.0 0.52 E -98.5 131.1 104.0 0.52 0.0 DA
DA
DG
DG
 9.379
2.960
1.882
6.086
 CB
CB
CB
N
 C2'
O3'
OP1
OP1
7enc 49 P20226 85.12 2e-126 EM
 2021-05-26 LYS CB:218 DP:218 115.0 0.575 E -64.3 133.9 115.0 0.575 0.0 DA
DA
DG
DG
 6.232
3.776
3.309
9.534
 CD
CB
CD
O
 O3'
O3'
OP2
OP1
7lbm 20 P20226 85.12 2e-126 EM
 2021-03-24 LYS T:218 P:218 110.0 0.55 E -74.6 128.1 110.0 0.55 0.0 DA
DA
DG
DG
DT
 7.697
3.394
1.926
6.338
9.868
 CB
CD
NZ
NZ
O
 O3'
O3'
OP1
OP2
O2
7nvr 25 P20226 85.12 2e-126 EM
 2021-05-05 LYS Y:218 O:218 114.0 0.57 E -93.3 141.9 114.0 0.57 0.0 DA
DA
DG
DG
 5.963
3.571
3.154
9.671
 NZ
CD
CD
CD
 O3'
O3'
OP1
OP2
7nvs 15 P20226 85.12 2e-126 EM
 2021-05-05 LYS O:218 O:218 117.0 0.585 E -85.0 142.2 117.0 0.585 0.0 DA
DA
DG
DG
 5.876
3.514
3.129
9.664
 NZ
CD
CD
CD
 O3'
O3'
OP1
OP2
7nvt 15 P20226 85.12 2e-126 EM
 2021-05-05 LYS O:218 O:218 117.0 0.585 E -82.7 141.8 117.0 0.585 0.0 DA
DA
DG
DG
 6.141
3.579
3.033
9.585
 NZ
CD
CD
CD
 O3'
O3'
OP1
OP2
7nvu 15 P20226 85.12 2e-126 EM
 2021-05-05 LYS O:218 O:218 115.0 0.575 E -81.0 138.0 115.0 0.575 0.0 DA
DA
DG
DG
 5.873
3.563
3.049
9.735
 NZ
CD
CD
CD
 O3'
O3'
OP1
OP2
7nvy 23 P20226 85.12 2e-126 EM
 2021-05-05 LYS W:218 O:218 115.0 0.575 E -84.2 142.3 115.0 0.575 0.0 DA
DA
DG
DG
 5.867
3.491
3.134
9.677
 NZ
CD
CD
CD
 O3'
O3'
OP1
OP2
7nvz 23 P20226 85.12 2e-126 EM
 2021-05-05 LYS W:218 O:218 116.0 0.58 E -82.6 141.4 116.0 0.58 0.0 DA
DA
DG
DG
 6.153
3.558
3.045
9.602
 NZ
CD
CD
CD
 O3'
O3'
OP1
OP2
7nw0 23 P20226 85.12 2e-126 EM
 2021-05-05 LYS W:218 O:218 116.0 0.58 E -80.7 137.4 116.0 0.58 0.0 DA
DA
DG
DG
 5.859
3.536
3.000
9.712
 NZ
CD
CD
CD
 O3'
O3'
OP1
OP2
1jfi 5 P20226 92.86 8e-123 X-RAY
 2001-07-11 LYS E:64 C:418 125.0 0.625 E -66.9 150.1 125.0 0.625 0.0 DA
DA
DG
HOH
 6.305
3.792
3.287
6.224
 NZ
CB
CD
CE
 O3'
O3'
OP1
O
1tgh 2 P20226 92.86 1e-122 X-RAY
 1996-08-01 LYS C:64 A:214 99.0 0.495 E -67.3 153.1 99.0 0.495 0.0 DA
DT
DA
DC
HOH
 4.603
3.415
3.293
9.517
2.063
 HZ1
HZ1
CD
CD
HZ2
 O3'
OP1
OP1
OP2
O
1nvp 3 P20226 94.38 1e-122 X-RAY
 2003-10-21 LYS C:60 A:218 128.0 0.64 E -88.0 149.7 128.0 0.64 0.0 DA
DA
DG
DG
HOH
 6.448
3.644
3.252
9.937
2.641
 CD
CB
CD
CG
NZ
 O3'
O3'
OP1
OP1
O
1c9b 4 P20226 94.38 2e-122 X-RAY
 2000-01-10 LYS L:61 B:218 126.0 0.63 E -86.6 145.0 126.0 0.63 0.0 DA
DA
DG
DG
HOH
 6.133
3.796
3.385
9.560
5.756
 NZ
CB
CD
CD
CE
 O3'
O3'
OP1
OP2
O
LYS N:61 F:218 99.0 0.495 E -82.6 150.2 NA NA NA
LYS P:61 J:218 127.0 0.635 E -86.7 150.5 NA NA NA
LYS R:61 N:218 111.0 0.555 E -83.9 147.3 NA NA NA
LYS T:61 R:218 117.0 0.585 E -85.1 148.0 NA NA NA
5n9g 2 P20226 94.38 2e-122 X-RAY
 2017-06-14 LYS B:79 B:218 117.0 0.585 E -79.5 147.4 117.0 0.585 0.0 A
DT
A
G
HOH
 6.466
3.390
3.195
8.100
6.426
 NZ
CB
CG
CG
N
 O3'
O3'
OP1
OP1
O
LYS G:79 G:218 117.0 0.585 E -79.7 147.6 NA NA NA
4roc 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 LYS B:62 B:218 117.0 0.585 E -80.6 147.8 117.0 0.585 0.0 DA
DT
DA
DG
HOH
 6.747
3.385
3.393
8.946
2.816
 CD
CB
CG
CG
NZ
 O3'
O3'
OP1
OP1
O
4rod 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 LYS B:62 B:218 116.0 0.58 E -76.5 147.7 116.0 0.58 0.0 DA
DT
DA
DG
 6.360
3.357
3.362
8.902
 NZ
CB
CG
CG
 O3'
O3'
OP1
OP1
4roe 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 LYS B:62 B:218 119.0 0.595 E -81.0 144.7 119.0 0.595 0.0 DA
DA
DG
DA
HOH
 6.593
3.504
3.321
9.716
2.892
 NZ
CB
CG
CG
NZ
 O3'
O3'
OP1
OP1
O
1cdw 3 P20226 93.82 2e-121 X-RAY
 1996-12-23 LYS C:60 A:214 123.0 0.615 E -84.9 146.6 123.0 0.615 0.0 DA
DA
DG
DG
HOH
 6.430
3.567
3.373
9.809
2.517
 CD
CB
CD
N
NZ
 O3'
O3'
OP1
OP1
O
1vtl 3 P28147 80.9 2e-104 X-RAY
 2011-07-13 LYS E:66 E:78 119.0 0.595 E -75.9 150.4 119.0 0.595 0.0 DA
DA
DG
DG
 5.322
3.360
3.208
8.786
 HZ3
HZ3
CG
H
 O3'
OP1
OP1
OP1
LYS F:66 F:78 111.0 0.555 E -86.9 155.2 NA NA NA
1vto 3 P28147 80.9 3e-104 X-RAY
 2011-07-13 LYS E:68 A:78 120.0 0.6 E -77.6 151.1 120.0 0.6 0.0 DA
DA
DG
DG
HOH
 5.828
3.602
3.496
9.036
1.237
 HZ1
CB
CD
H
HZ2
 O3'
O3'
OP1
OP1
H2
LYS F:68 B:1078 121.0 0.605 E -83.0 153.5 NA NA NA
1qn3 1 P28147 80.9 3e-104 X-RAY
 2000-02-06 LYS A:78 A:78 111.0 0.555 E -75.9 149.6 111.0 0.555 0.0 DA
DC
DG
HOH
 6.296
3.880
3.629
2.849
 NZ
CB
CG
NZ
 O3'
O3'
OP1
O
LYS B:78 B:78 108.0 0.54 E -73.6 143.4 NA NA NA
1qn4 1 P28147 80.9 3e-104 X-RAY
 2000-02-06 LYS A:78 A:78 120.0 0.6 E -76.3 152.7 120.0 0.6 0.0 DA
DA
DT
DG
HOH
 6.608
3.480
3.231
9.867
2.739
 NZ
CB
CG
CG
NZ
 O3'
O3'
OP1
P
O
LYS B:78 B:78 119.0 0.595 E -80.8 150.0 NA NA NA
1qn5 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:78 A:78 109.0 0.545 E -78.5 151.0 109.0 0.545 0.0 DG
DA
DG
HOH
 6.725
3.672
3.668
2.683
 NZ
CB
CG
NZ
 O3'
O3'
OP1
O
LYS B:78 B:78 107.0 0.535 E -76.5 147.0 NA NA NA
1qn6 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:78 A:78 110.0 0.55 E -73.5 150.9 110.0 0.55 0.0 DT
DA
DG
HOH
 6.686
3.626
3.623
3.039
 CD
CB
CG
NZ
 O3'
O3'
OP1
O
LYS B:78 B:78 109.0 0.545 E -78.6 148.1 NA NA NA
1qn7 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:78 A:78 113.0 0.565 E -76.2 155.7 113.0 0.565 0.0 DA
DA
DG
DG
HOH
 6.210
3.504
3.390
9.826
3.806
 NZ
CB
CG
CG
CD
 O3'
O3'
OP1
OP2
O
LYS B:78 B:78 109.0 0.545 E -76.8 149.7 NA NA NA
1qn8 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:78 A:78 119.0 0.595 E -79.8 144.4 119.0 0.595 0.0 DA
DA
DG
HOH
 6.233
3.647
3.724
3.166
 NZ
CD
CD
NZ
 O3'
O3'
OP1
O
LYS B:78 B:78 123.0 0.615 E -81.1 152.1 NA NA NA
1qn9 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:78 A:78 123.0 0.615 E -79.6 155.6 123.0 0.615 0.0 DA
DA
DG
HOH
 6.354
3.600
3.813
2.694
 NZ
CD
CD
NZ
 O3'
O3'
OP1
O
LYS B:78 B:78 108.0 0.54 E -74.3 153.9 NA NA NA
1qna 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:78 A:78 112.0 0.56 E -73.9 151.0 112.0 0.56 0.0 DA
DA
DG
HOH
 6.897
3.636
3.666
3.142
 NZ
CB
CG
CE
 O3'
O3'
OP1
O
LYS B:78 B:78 109.0 0.545 E -72.6 146.2 NA NA NA
1qnb 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:78 A:78 113.0 0.565 E -74.5 144.2 113.0 0.565 0.0 DA
DT
DG
DG
HOH
 6.237
3.565
3.424
9.486
2.549
 NZ
CB
CG
CB
NZ
 O3'
O3'
OP1
OP1
O
LYS B:78 B:78 120.0 0.6 E -84.6 145.2 NA NA NA
1qnc 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:78 A:78 118.0 0.59 E -78.0 150.7 118.0 0.59 0.0 DA
DA
DG
DG
HOH
 6.580
3.426
3.465
9.976
3.171
 NZ
CD
CD
CD
NZ
 O3'
O3'
OP1
OP2
O
LYS B:78 B:78 117.0 0.585 E -84.4 149.4 NA NA NA
1qne 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LYS A:78 A:78 120.0 0.6 E -78.1 150.9 120.0 0.6 0.0 DA
DA
DG
HOH
 6.650
3.587
3.473
2.856
 CD
CB
CD
NZ
 O3'
O3'
OP1
O
LYS B:78 B:78 119.0 0.595 E -83.1 152.9 NA NA NA
1vok 1 P28147 80.9 3e-104 X-RAY
 1996-11-08 LYS A:78 A:78 95.0 0.475 E -78.2 141.4 95.0 0.475 0.0 HOH
 2.534
 NZ
 O
LYS B:78 B:78 106.0 0.53 E -73.2 137.7 NA NA NA
1vol 4 P28147 80.9 3e-104 X-RAY
 1996-11-08 LYS D:78 B:78 114.0 0.57 E -63.7 120.1 114.0 0.57 0.0 DA
DA
DG
 5.834
3.792
3.037
 NZ
CD
CD
 O3'
O3'
OP1
6ueo 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 LYS A:97 A:78 113.0 0.565 E -76.8 148.9 113.0 0.565 0.0 DA
DA
DG
HOH
 5.964
3.800
3.666
2.451
 CD
CB
CG
NZ
 O3'
O3'
OP1
O
LYS D:97 D:78 113.0 0.565 E -69.6 153.3 NA NA NA
LYS G:97 G:78 112.0 0.56 E -73.6 149.3 NA NA NA
LYS J:97 J:78 100.0 0.5 E -78.6 151.3 NA NA NA
6uep 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 LYS A:97 B:78 111.0 0.555 E -76.7 144.0 111.0 0.555 0.0 DA
DC
DG
FMT
HOH
 6.258
3.713
3.712
4.074
3.569
 NZ
CB
CG
NZ
CG
 O3'
O3'
OP1
O1
O
LYS D:97 A:78 107.0 0.535 E -73.1 146.7 NA NA NA
6ueq 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 LYS A:97 B:78 109.0 0.545 E -76.3 157.1 109.0 0.545 0.0 DA
DA
DC
HOH
 6.743
3.721
4.184
3.136
 NZ
CB
CD
NZ
 O3'
O3'
OP1
O
6uer 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 LYS A:97 A:78 103.0 0.515 E -87.2 143.0 103.0 0.515 0.0 DA
DC
DG
HOH
 6.579
3.903
3.687
9.349
 CD
CB
CG
CD
 O3'
O3'
OP1
O
LYS D:97 B:78 113.0 0.565 E -82.3 153.5 NA NA NA
6njq 1 P28147 80.9 8e-104 X-RAY
 2019-10-30 LYS A:98 B:78 114.0 0.57 E -64.0 144.9 114.0 0.57 0.0 DA
DC
DG
 5.818
3.769
3.645
 CG
CG
CD
 O3'
C5'
OP1
LYS D:98 A:78 106.0 0.53 E -75.4 156.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6sj96-f1 1 Q6SJ96 100.0 0.0 LYS A:255 A:255 51.0 0.255 E -64.9 142.0
af-p20226-f1 1 P20226 85.12 8e-127 LYS A:218 A:218 137.0 0.685 E -67.7 140.4