Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 55902592 . A C CCDS9724.1:NM_199047.2:c.669caT>caG_NP_950248.1:p.223H>Q Homo sapiens TATA-box binding protein like 2 (TBPL2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5fur 1 P20226 85.12 2e-126 EM
 2016-04-06 ARG A:186 A:186 147.0 0.653 H -97.9 -29.0 141.0 0.627 0.026 D:P52657:0.027
5iy6 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:186 P:186 130.0 0.578 H -63.7 -46.0 123.0 0.547 0.031 N:P52655:0.013
O:P52657:0.018
5iy7 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:186 P:186 133.0 0.591 H -67.4 -52.1 106.0 0.471 0.12 N:P52655:0.12
O:P52657:0.018
5iy8 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:186 P:186 120.0 0.533 H -67.1 -49.9 114.0 0.507 0.026 N:P52655:0.022
O:P52657:0.022
5iy9 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:186 P:186 159.0 0.707 H -72.9 -46.2 146.0 0.649 0.058 O:P52657:0.058
5iya 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:186 P:186 129.0 0.573 H -63.8 -46.0 122.0 0.542 0.031 N:P52655:0.013
O:P52657:0.018
5iyb 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:186 P:186 135.0 0.6 H -67.4 -52.1 106.0 0.471 0.129 N:P52655:0.129
O:P52657:0.022
5iyc 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:186 P:186 118.0 0.524 H -67.1 -49.9 112.0 0.498 0.026 N:P52655:0.027
O:P52657:0.027
5iyd 16 P20226 85.12 2e-126 EM
 2016-05-18 ARG P:186 P:186 155.0 0.689 H -72.9 -46.2 143.0 0.636 0.053 O:P52657:0.053
6mzd 11 P20226 85.12 2e-126 EM
 2018-11-28 ARG K:186 T:186 162.0 0.72 H -94.8 -29.5 114.0 0.507 0.213 A:P21675:0.213
6mzl 15 P20226 85.12 2e-126 EM
 2018-11-28 ARG T:186 T:186 162.0 0.72 H -94.8 -29.5 114.0 0.507 0.213 A:P21675:0.213
6mzm 12 P20226 85.12 2e-126 EM
 2018-11-28 ARG L:186 T:186 161.0 0.716 H -96.5 -37.2 154.0 0.684 0.032 P:P52657:0.031
6o9l 16 P20226 85.12 2e-126 EM
 2019-05-29 ARG P:186 P:186 127.0 0.564 H -86.4 -19.9 119.0 0.529 0.035 N:P52655:0.027
O:P52657:0.013
7edx 12 P20226 85.12 2e-126 EM
 2021-05-05 ARG L:186 P:186 144.0 0.64 H -96.9 -35.7 122.0 0.542 0.098 M:P52655:0.098
7eg7 12 P20226 85.12 2e-126 EM
 2021-05-05 ARG L:186 P:186 143.0 0.636 H -96.9 -35.6 120.0 0.533 0.103 M:P52655:0.102
7eg8 12 P20226 85.12 2e-126 EM
 2021-05-05 ARG L:186 P:186 141.0 0.627 H -97.0 -35.5 133.0 0.591 0.036 M:P52655:0.036
7eg9 12 P20226 85.12 2e-126 EM
 2021-05-05 ARG L:186 P:186 146.0 0.649 H -96.9 -35.6 124.0 0.551 0.098 K:P52657:0.004
M:P52655:0.093
7ega 12 P20226 85.12 2e-126 EM
 2021-05-05 ARG L:186 P:186 146.0 0.649 H -96.9 -35.5 138.0 0.613 0.036 M:P52655:0.036
7egb 22 P20226 85.12 2e-126 EM
 2021-05-05 ARG V:186 P:186 165.0 0.733 H -94.7 -45.0 149.0 0.662 0.071 W:P52655:0.031
U:P52657:0.04
7egc 22 P20226 85.12 2e-126 EM
 2021-05-12 ARG V:186 P:186 148.0 0.658 H -97.0 -35.5 140.0 0.622 0.036 U:P52657:0.036
7egd 12 P20226 85.12 2e-126 EM
 2021-05-12 ARG L:186 P:186 166.0 0.738 H -94.5 -45.1 166.0 0.738 0.0
7ege 11 P20226 85.12 2e-126 EM
 2021-05-12 ARG K:186 P:186 169.0 0.751 H -94.5 -45.0 169.0 0.751 0.0
7egf 1 P20226 85.12 2e-126 EM
 2021-05-05 ARG A:186 P:186 167.0 0.742 H -94.5 -45.1 167.0 0.742 0.0
7egi 12 P20226 85.12 2e-126 EM
 2021-05-12 ARG L:186 P:186 165.0 0.733 H -94.6 -45.1 155.0 0.689 0.044 K:P52657:0.044
7egj 12 P20226 85.12 2e-126 EM
 2021-05-12 ARG L:186 P:186 167.0 0.742 H -94.5 -45.2 163.0 0.724 0.018 K:P52657:0.018
7ena 5 P20226 85.12 2e-126 EM
 2021-05-26 ARG E:186 DP:186 144.0 0.64 H -98.4 -60.1 129.0 0.573 0.067 D:P52657:0.009
F:None:0.062
7enc 49 P20226 85.12 2e-126 EM
 2021-05-26 ARG CB:186 DP:186 150.0 0.667 H -68.8 -43.4 132.0 0.587 0.08 DB:None:0.08
7lbm 20 P20226 85.12 2e-126 EM
 2021-03-24 ARG T:186 P:186 117.0 0.52 H -102.8 -14.4 117.0 0.52 0.0
7nvr 25 P20226 85.12 2e-126 EM
 2021-05-05 ARG Y:186 O:186 142.0 0.631 H -98.1 -21.2 135.0 0.6 0.031 CA:P52655:0.031
7nvs 15 P20226 85.12 2e-126 EM
 2021-05-05 ARG O:186 O:186 143.0 0.636 H -102.8 -35.6 141.0 0.627 0.009 T:P52657:0.009
7nvt 15 P20226 85.12 2e-126 EM
 2021-05-05 ARG O:186 O:186 145.0 0.644 H -101.3 -33.6 142.0 0.631 0.013 T:P52657:0.013
7nvu 15 P20226 85.12 2e-126 EM
 2021-05-05 ARG O:186 O:186 140.0 0.622 H -98.1 -29.2 139.0 0.618 0.004 T:P52657:0.004
7nvy 23 P20226 85.12 2e-126 EM
 2021-05-05 ARG W:186 O:186 145.0 0.644 H -97.4 -34.5 143.0 0.636 0.008 BA:P52657:0.009
7nvz 23 P20226 85.12 2e-126 EM
 2021-05-05 ARG W:186 O:186 147.0 0.653 H -98.4 -32.5 144.0 0.64 0.013 BA:P52657:0.013
7nw0 23 P20226 85.12 2e-126 EM
 2021-05-05 ARG W:186 O:186 140.0 0.622 H -96.9 -30.0 139.0 0.618 0.004 BA:P52657:0.004
1jfi 5 P20226 92.86 8e-123 X-RAY
 2001-07-11 ARG E:32 C:386 139.0 0.618 H -99.3 -29.0 139.0 0.618 0.0
1tgh 2 P20226 92.86 1e-122 X-RAY
 1996-08-01 ARG C:32 A:182 164.0 0.729 H -97.5 -31.9 164.0 0.729 0.0
1nvp 3 P20226 94.38 1e-122 X-RAY
 2003-10-21 ARG C:28 A:186 148.0 0.658 H -98.3 -28.7 141.0 0.627 0.031 F:P52657:0.031
 HOH
 4.844
 N
 O
1c9b 4 P20226 94.38 2e-122 X-RAY
 2000-01-10 ARG L:29 B:186 154.0 0.684 H -66.0 -50.1 154.0 0.684 0.0 HOH
 6.843
 O
 O
ARG N:29 F:186 204.0 0.907 H -72.3 -37.8 NA NA NA
ARG P:29 J:186 154.0 0.684 H -65.9 -54.4 NA NA NA
ARG R:29 N:186 151.0 0.671 H -62.3 -55.7 NA NA NA
ARG T:29 R:186 133.0 0.591 H -64.6 -51.5 NA NA NA
5n9g 2 P20226 94.38 2e-122 X-RAY
 2017-06-14 ARG B:47 B:186 148.0 0.658 H -99.4 -12.2 102.0 0.453 0.205 A:Q9HAW0:0.204
ARG G:47 G:186 149.0 0.662 H -98.5 1.8 NA NA NA
4roc 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 ARG B:30 B:186 173.0 0.769 H -102.9 -12.0 106.0 0.471 0.298 A:Q9HAW0:0.298
 HOH
 2.739
 O
 O
4rod 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 ARG B:30 B:186 172.0 0.764 H -99.6 -14.1 104.0 0.462 0.302 A:Q9HAW0:0.302
 HOH
 7.582
 O
 O
4roe 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 ARG B:30 B:186 173.0 0.769 H -99.4 -8.5 103.0 0.458 0.311 A:Q9HAW0:0.311
 HOH
 3.290
 CD
 O
1cdw 3 P20226 93.82 2e-121 X-RAY
 1996-12-23 ARG C:28 A:182 131.0 0.582 H -85.7 -36.4 131.0 0.582 0.0 HOH
 2.631
 O
 O
1vtl 3 P28147 80.9 2e-104 X-RAY
 2011-07-13 GLN E:34 E:46 107.0 0.594 H -71.6 -44.9 107.0 0.594 0.0
GLN F:34 F:46 130.0 0.722 H -85.1 -20.5 NA NA NA
1vto 3 P28147 80.9 3e-104 X-RAY
 2011-07-13 GLN E:36 A:46 118.0 0.656 H -81.8 -43.2 118.0 0.656 0.0 HOH
 2.622
 OE1
 H1
GLN F:36 B:1046 141.0 0.783 H -83.3 -11.5 NA NA NA
1qn3 1 P28147 80.9 3e-104 X-RAY
 2000-02-06 GLN A:46 A:46 120.0 0.667 H -69.7 -26.6 120.0 0.667 0.0 HOH
 2.686
 OE1
 O
GLN B:46 B:46 126.0 0.7 H -106.0 -33.8 NA NA NA
1qn4 1 P28147 80.9 3e-104 X-RAY
 2000-02-06 GLN A:46 A:46 114.0 0.633 H -81.7 -44.1 114.0 0.633 0.0 HOH
 4.500
 O
 O
GLN B:46 B:46 138.0 0.767 H -76.3 -17.8 NA NA NA
1qn5 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 GLN A:46 A:46 112.0 0.622 H -75.6 -45.3 112.0 0.622 0.0 HOH
 2.667
 OE1
 O
GLN B:46 B:46 138.0 0.767 H -96.6 -30.4 NA NA NA
1qn6 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 GLN A:46 A:46 120.0 0.667 H -75.6 -35.7 120.0 0.667 0.0 HOH
 4.905
 N
 O
GLN B:46 B:46 122.0 0.678 H -84.6 -35.4 NA NA NA
1qn7 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 GLN A:46 A:46 112.0 0.622 H -81.6 -36.5 112.0 0.622 0.0 HOH
 9.809
 OE1
 O
GLN B:46 B:46 140.0 0.778 H -64.1 -19.3 NA NA NA
1qn8 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 GLN A:46 A:46 118.0 0.656 H -81.0 -39.0 118.0 0.656 0.0 HOH
 2.764
 NE2
 O
GLN B:46 B:46 127.0 0.706 H -90.5 -30.7 NA NA NA
1qn9 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 GLN A:46 A:46 117.0 0.65 H -73.3 -32.0 117.0 0.65 0.0 HOH
 5.712
 N
 O
GLN B:46 B:46 123.0 0.683 H -78.9 -29.7 NA NA NA
1qna 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 GLN A:46 A:46 115.0 0.639 H -74.6 -46.4 115.0 0.639 0.0 HOH
 2.554
 OE1
 O
GLN B:46 B:46 137.0 0.761 H -92.5 -31.9 NA NA NA
1qnb 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 GLN A:46 A:46 108.0 0.6 H -66.8 -45.2 108.0 0.6 0.0 HOH
 2.437
 NE2
 O
GLN B:46 B:46 123.0 0.683 H -93.6 -43.2 NA NA NA
1qnc 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 GLN A:46 A:46 116.0 0.644 H -71.2 -32.2 116.0 0.644 0.0 HOH
 6.339
 C
 O
GLN B:46 B:46 118.0 0.656 H -81.1 -45.1 NA NA NA
1qne 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 GLN A:46 A:46 122.0 0.678 H -83.0 -41.3 122.0 0.678 0.0 HOH
 2.105
 NE2
 O
GLN B:46 B:46 141.0 0.783 H -84.0 -10.5 NA NA NA
1vok 1 P28147 80.9 3e-104 X-RAY
 1996-11-08 GLN A:46 A:46 104.0 0.578 H -77.9 -26.3 104.0 0.578 0.0 HOH
 2.756
 OE1
 O
GLN B:46 B:46 101.0 0.561 H -87.1 -25.5 NA NA NA
1vol 4 P28147 80.9 3e-104 X-RAY
 1996-11-08 GLN D:46 B:46 145.0 0.806 H -121.0 -28.2 145.0 0.806 0.0
6ueo 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 GLN A:65 A:46 141.0 0.783 H -83.7 -50.4 141.0 0.783 0.0 HOH
 3.880
 N
 O
GLN D:65 D:46 108.0 0.6 H -89.6 -36.1 NA NA NA
GLN G:65 G:46 104.0 0.578 H -103.2 -26.2 NA NA NA
GLN J:65 J:46 143.0 0.794 H -81.3 -46.0 NA NA NA
6uep 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 GLN A:65 B:46 113.0 0.628 H -90.0 -26.6 113.0 0.628 0.0 FMT
HOH
 5.543
4.411
 O
O
 O1
O
GLN D:65 A:46 93.0 0.517 H -73.7 -42.4 NA NA NA
6ueq 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 GLN A:65 B:46 139.0 0.772 H -81.2 -45.4 139.0 0.772 0.0 HOH
 6.702
 O
 O
6uer 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 GLN A:65 A:46 99.0 0.55 H -79.0 -11.3 99.0 0.55 0.0
GLN D:65 B:46 125.0 0.694 H -77.6 -7.6 NA NA NA
6njq 1 P28147 80.9 8e-104 X-RAY
 2019-10-30 GLN A:66 B:46 163.0 0.906 H -93.0 -23.0 163.0 0.906 0.0
GLN D:66 A:46 136.0 0.756 H -96.1 -34.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6sj96-f1 1 Q6SJ96 100.0 0.0 HIS A:223 A:223 111.0 0.569 H -105.3 -18.9
af-p20226-f1 1 P20226 85.12 8e-127 ARG A:186 A:186 162.0 0.72 H -89.7 -27.8