Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 20824511 . G A CCDS41910.1:NM_005484.3:c.1186Gac>Aac_NP_005475.2:p.396D>N Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6x0l 2 Q9UGN5 97.71 0.0 EM
 2020-09-16 ASP B:403 P:383 83.0 0.553 T -67.2 -11.0 18.0 0.12 0.433 A:Q9NWY4:0.433
ASP C:403 NA:NA DO NA DO DO DO NA NA NA
6x0m 2 Q9UGN5 97.71 0.0 EM
 2020-09-16 ASP B:403 P:383 73.0 0.487 T -69.6 -12.1 7.0 0.047 0.44 A:Q9NWY4:0.44
ASP D:403 p:383 81.0 0.54 T -68.2 -9.4 9.0 0.06 0.48 C:Q9NWY4:0.48
6x0n 8 Q9UGN5 97.71 0.0 EM
 2020-09-16 ASP V:403 P:383 83.0 0.553 T -67.1 -11.0 6.0 0.04 0.513 U:Q9NWY4:0.513
ASP W:403 NA:NA DO NA DO DO DO NA NA NA
6usj 7 Q9UGN5 97.36 0.0 EM
 2020-10-14 ASP U:403 NA:NA DO NA DO DO DO NA NA NA
ASP V:403 NA:NA DO NA DO DO DO NA NA NA
7aeo 1 Q9UGN5 100.0 0.0 X-RAY
 2021-05-19 ASP A:309 A:396 87.0 0.58 T -89.4 4.1 87.0 0.58 0.0
4zzx 1 Q9UGN5 100.0 0.0 X-RAY
 2015-08-12 ASP A:176 A:396 74.0 0.493 T -76.6 -10.1 74.0 0.493 0.0 HOH
 3.543
 O
 O
ASP B:176 B:396 77.0 0.513 T -71.8 -7.1 NA NA NA
4zzy 1 Q9UGN5 100.0 0.0 X-RAY
 2015-08-12 ASP A:176 A:396 85.0 0.567 T -67.8 -13.1 85.0 0.567 0.0 HOH
 7.289
 OD1
 O
3kcz 1 Q9UGN5 99.42 0.0 X-RAY
 2009-11-10 ASP A:185 A:396 94.0 0.627 T -74.2 -7.6 94.0 0.627 0.0 GOL
HOH
 2.864
2.645
 OD2
O
 O1
O
ASP B:185 B:396 97.0 0.647 T -76.2 -4.6 NA NA NA
3kjd 1 Q9UGN5 99.42 0.0 X-RAY
 2009-11-17 ASP A:185 A:396 98.0 0.653 T -81.9 -6.0 98.0 0.653 0.0 GOL
HOH
 2.702
2.589
 OD2
O
 O3
O
ASP B:185 B:396 100.0 0.667 T -72.7 -8.7 NA NA NA
4pjv 1 Q9UGN5 99.42 0.0 X-RAY
 2014-09-24 ASP A:185 A:396 93.0 0.62 T -76.2 -15.5 93.0 0.62 0.0 GOL
HOH
 3.061
2.705
 OD2
OD1
 O1
O
ASP B:185 B:396 98.0 0.653 T -77.5 -5.5 NA NA NA
4tvj 1 Q9UGN5 99.42 0.0 X-RAY
 2015-07-08 ASP A:185 A:396 98.0 0.653 T -70.6 -16.9 98.0 0.653 0.0 GOL
HOH
 2.630
2.638
 OD2
O
 O3
O
ASP B:185 B:396 100.0 0.667 T -76.2 -8.8 NA NA NA
1gs0 1 O88554 90.31 0.0 X-RAY
 2002-12-19 ASP A:166 A:372 95.0 0.633 S -66.8 4.1 95.0 0.633 0.0 HOH
 7.413
 OD2
 O
ASP B:166 B:372 99.0 0.66 S -67.3 3.5 NA NA NA
5dsy 1 Q9UGN5 100.0 1e-176 X-RAY
 2016-07-27 ASP A:93 A:383 96.0 0.64 T -75.5 -1.8 96.0 0.64 0.0 HOH
 7.912
 OD1
 O
ASP B:93 B:383 91.0 0.607 T -75.3 -2.7 NA NA NA
ASP C:93 C:383 104.0 0.693 T -76.3 -0.7 NA NA NA
ASP D:93 D:383 98.0 0.653 T -80.8 -1.1 NA NA NA
6tx3 1 Q9UGN5 100.0 1e-176 X-RAY
 2020-02-19 ASP A:93 B:383 75.0 0.5 T -75.5 -2.8 9.0 0.06 0.44 B:Q9NWY4:0.44

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9ugn5-f1 1 Q9UGN5 100.0 0.0 ASP A:396 A:396 70.0 0.467 T -75.4 -11.7