Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 20824787 . T A CCDS41910.1:NM_005484.3:c.1307gTg>gAg_NP_005475.2:p.436V>E Homo sapiens poly(ADP-ribose) polymerase 2 (PARP2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6x0l 2 Q9UGN5 97.71 0.0 EM
 2020-09-16 VAL B:443 P:423 6.0 0.039 H -53.2 -36.9 6.0 0.039 0.0
VAL C:443 NA:NA DO NA DO DO DO NA NA NA
6x0m 2 Q9UGN5 97.71 0.0 EM
 2020-09-16 VAL B:443 P:423 0.0 0.0 H -56.9 -34.7 0.0 0.0 0.0
VAL D:443 p:423 1.0 0.006 H -59.1 -35.8 1.0 0.006 0.0
6x0n 8 Q9UGN5 97.71 0.0 EM
 2020-09-16 VAL V:443 P:423 5.0 0.032 H -53.3 -36.9 5.0 0.032 0.0
VAL W:443 NA:NA DO NA DO DO DO NA NA NA
6usj 7 Q9UGN5 97.36 0.0 EM
 2020-10-14 VAL U:443 NA:NA DO NA DO DO DO NA NA NA
VAL V:443 NA:NA DO NA DO DO DO NA NA NA
7aeo 1 Q9UGN5 100.0 0.0 X-RAY
 2021-05-19 VAL A:349 A:436 52.0 0.335 H -57.4 -57.4 52.0 0.335 0.0
4zzx 1 Q9UGN5 100.0 0.0 X-RAY
 2015-08-12 VAL A:216 A:436 0.0 0.0 H -57.9 -43.5 0.0 0.0 0.0 HOH
 2.944
 N
 O
VAL B:216 B:436 1.0 0.006 H -59.0 -45.6 NA NA NA
4zzy 1 Q9UGN5 100.0 0.0 X-RAY
 2015-08-12 VAL A:216 A:436 0.0 0.0 H -60.4 -44.7 0.0 0.0 0.0 HOH
 2.807
 N
 O
3kcz 1 Q9UGN5 99.42 0.0 X-RAY
 2009-11-10 VAL A:225 A:436 1.0 0.006 H -65.2 -43.7 1.0 0.006 0.0 HOH
 3.169
 N
 O
VAL B:225 B:436 0.0 0.0 H -58.8 -44.9 NA NA NA
3kjd 1 Q9UGN5 99.42 0.0 X-RAY
 2009-11-17 VAL A:225 A:436 0.0 0.0 H -59.9 -44.5 0.0 0.0 0.0 HOH
 2.989
 N
 O
VAL B:225 B:436 1.0 0.006 H -63.7 -44.9 NA NA NA
4pjv 1 Q9UGN5 99.42 0.0 X-RAY
 2014-09-24 VAL A:225 A:436 0.0 0.0 H -61.4 -42.9 0.0 0.0 0.0 GOL
HOH
 8.965
3.281
 C
N
 O1
O
VAL B:225 B:436 2.0 0.013 H -57.8 -48.8 NA NA NA
4tvj 1 Q9UGN5 99.42 0.0 X-RAY
 2015-07-08 VAL A:225 A:436 0.0 0.0 H -61.4 -43.0 0.0 0.0 0.0 09L
HOH
 9.649
3.066
 C
N
 OAB
O
VAL B:225 B:436 1.0 0.006 H -63.2 -41.4 NA NA NA
1gs0 1 O88554 90.31 0.0 X-RAY
 2002-12-19 VAL A:206 A:412 4.0 0.026 H -63.9 -50.4 4.0 0.026 0.0 HOH
 9.306
 C
 O
VAL B:206 B:412 7.0 0.045 H -63.3 -52.2 NA NA NA
5dsy 1 Q9UGN5 100.0 1e-176 X-RAY
 2016-07-27 VAL A:133 A:423 52.0 0.335 H -58.6 -48.1 52.0 0.335 0.0 UHB
HOH
 5.710
3.158
 C
N
 N35
O
VAL B:133 B:423 54.0 0.348 H -59.7 -47.6 NA NA NA
VAL C:133 C:423 52.0 0.335 H -57.7 -48.8 NA NA NA
VAL D:133 D:423 53.0 0.342 H -58.9 -48.5 NA NA NA
6tx3 1 Q9UGN5 100.0 1e-176 X-RAY
 2020-02-19 VAL A:133 B:423 56.0 0.361 H -58.9 -47.7 56.0 0.361 0.0 UHB
 5.693
 C
 N35

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9ugn5-f1 1 Q9UGN5 100.0 0.0 VAL A:436 A:436 1.0 0.006 H -62.6 -43.4