Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 54416859 . C A CCDS9715.1:NM_001202.3:c.1118tGt>tTt_NP_001193.2:p.373C>F Homo sapiens bone morphogenetic protein 4 (BMP4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6omn 1 P12643 88.89 3e-69 X-RAY
 2019-05-08 CYS A:73 E:79 24.0 0.178 E -98.2 110.6 21.0 0.156 0.022 B:P12643:0.022
 NAG
HOH
 6.747
3.952
 SG
O
 C8
O
CYS B:73 F:79 21.0 0.156 E -83.5 110.5 19.0 0.141 0.015 A:P12643:0.015
 NAG
HOH
 6.771
7.187
 SG
N
 C8
O
CYS C:73 G:79 18.0 0.133 E -86.3 110.9 NA NA NA
CYS D:73 H:79 11.0 0.081 E -77.5 111.5 NA NA NA
2h64 1 P12643 85.71 1e-68 X-RAY
 2007-04-10 CYS A:79 A:79 10.0 0.074 E -81.9 113.7 8.0 0.059 0.015 A:P12643:0.015
 HOH
 2.666
 O
 O
1es7 1 P12643 87.5 2e-68 X-RAY
 2000-10-07 CYS A:81 A:79 14.0 0.104 E -83.6 110.5 13.0 0.096 0.008 C:P12643:0.007
 HOH
 2.868
 N
 O
CYS C:81 C:579 13.0 0.096 E -80.6 108.5 12.0 0.089 0.007 A:P12643:0.007
 HOH
 3.067
 N
 O
2qj9 1 P12643 87.5 2e-68 X-RAY
 2008-01-15 CYS A:81 B:79 12.0 0.089 E -79.2 107.2 11.0 0.081 0.008 B:P12643:0.007
 HOH
 2.739
 N
 O
CYS B:81 A:79 12.0 0.089 E -75.5 108.3 11.0 0.081 0.008 A:P12643:0.007
 HOH
 2.719
 O
 O
2qja 1 P12643 87.5 2e-68 X-RAY
 2008-01-15 CYS A:81 A:79 11.0 0.081 E -90.9 107.1 10.0 0.074 0.007 B:P12643:0.007
 HOH
 5.507
 O
 O
CYS B:81 B:79 13.0 0.096 E -84.3 108.7 12.0 0.089 0.007 A:P12643:0.007
 HOH
 7.961
 C
 O
2qjb 1 P12643 87.5 2e-68 X-RAY
 2008-01-15 CYS A:81 A:79 13.0 0.096 E -90.7 112.0 11.0 0.081 0.015 B:P12643:0.015
 CL
HOH
 8.269
5.326
 C
O
 CL
O
CYS B:81 B:79 13.0 0.096 E -79.3 111.7 12.0 0.089 0.007 A:P12643:0.007
 CL
HOH
 8.375
2.972
 C
O
 CL
O
1rew 1 P12643 87.5 4e-68 X-RAY
 2004-05-04 CYS A:79 A:79 12.0 0.089 E -83.6 115.3 11.0 0.081 0.008 B:P12643:0.007
 HOH
 2.987
 N
 O
CYS B:79 B:79 11.0 0.081 E -82.7 117.1 10.0 0.074 0.007 A:P12643:0.007
 HOH
 2.934
 N
 O
2goo 1 P12643 87.5 4e-68 X-RAY
 2006-05-09 CYS A:79 A:79 14.0 0.104 E -86.1 115.2 14.0 0.104 0.0 HOH
 2.927
 O
 O
CYS D:79 D:79 13.0 0.096 E -85.3 111.9 13.0 0.096 0.0 HOH
 3.166
 N
 O
2h62 1 P12643 87.5 4e-68 X-RAY
 2007-04-10 CYS A:79 A:79 11.0 0.081 E -82.3 113.9 9.0 0.067 0.014 B:P12643:0.015
 HOH
 2.418
 O
 O
CYS B:79 B:79 12.0 0.089 E -81.3 117.0 10.0 0.074 0.015 A:P12643:0.015
 HOH
 2.498
 O
 O
3bmp 1 P12643 87.5 4e-68 X-RAY
 2000-03-12 CYS A:79 A:79 13.0 0.096 E -95.7 93.0 12.0 0.089 0.007 A:P12643:0.007
 HOH
 7.115
 SG
 O
4uhy 1 P12643 87.5 4e-68 X-RAY
 2015-05-06 CYS A:79 A:361 11.0 0.081 E -80.1 106.1 10.0 0.074 0.007 B:P12643:0.007
CYS B:79 B:361 11.0 0.081 E -75.2 107.1 10.0 0.074 0.007 A:P12643:0.007
4uhz 1 P12643 87.5 4e-68 X-RAY
 2015-05-06 CYS A:79 A:361 13.0 0.096 E -79.8 103.3 13.0 0.096 0.0 SO4
SO4
SO4
 9.633
9.727
9.688
 SG
SG
CB
 O2
O1
O3
4ui0 1 P12643 87.5 4e-68 X-RAY
 2015-05-06 CYS A:79 A:361 13.0 0.096 E -81.6 104.4 11.0 0.081 0.015 B:P12643:0.015
 CL
HOH
 8.765
2.750
 C
N
 CL
O
CYS B:79 B:361 14.0 0.104 E -80.6 105.2 12.0 0.089 0.015 A:P12643:0.015
 CL
HOH
 8.814
3.656
 C
O
 CL
O
4ui1 1 P12643 87.5 4e-68 X-RAY
 2015-05-06 CYS A:79 A:361 14.0 0.104 E -81.7 111.2 14.0 0.104 0.0 HOH
 2.822
 N
 O
CYS B:79 B:361 14.0 0.104 E -81.7 110.4 NA NA NA
4ui2 2 P12643 87.5 4e-68 X-RAY
 2015-05-06 CYS B:79 B:361 15.0 0.111 E -77.8 118.4 12.0 0.089 0.022 B:P12643:0.022
3bk3 1 P12643 85.71 5e-68 X-RAY
 2008-05-27 CYS A:79 A:79 15.0 0.111 E -90.1 111.1 13.0 0.096 0.015 B:P12643:0.015
 HOH
 2.739
 N
 O
CYS B:79 B:79 14.0 0.104 E -86.4 117.3 13.0 0.096 0.008 A:P12643:0.007
 HOH
 3.648
 O
 O
1reu 1 P12643 90.2 5e-68 X-RAY
 2004-05-04 CYS A:68 A:79 11.0 0.081 E -84.3 113.2 10.0 0.074 0.007 A:P12643:0.007
 HOH
 5.406
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p12644-f1 1 P12644 100.0 0.0 CYS A:373 A:373 20.0 0.148 E -80.2 110.6