Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 54416877 . C A CCDS9715.1:NM_001202.3:c.1100aGt>aTt_NP_001193.2:p.367S>I Homo sapiens bone morphogenetic protein 4 (BMP4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6omn 1 P12643 88.89 3e-69 X-RAY
 2019-05-08 LYS A:67 E:73 189.0 0.945 T -57.9 -27.3 179.0 0.895 0.05 B:P12643:0.05
LYS B:67 F:73 195.0 0.975 T -64.7 -23.3 191.0 0.955 0.02 A:P12643:0.02
 HOH
 2.682
 O
 O
LYS C:67 G:73 191.0 0.955 T -67.6 -16.9 NA NA NA
LYS D:67 H:73 189.0 0.945 T -67.5 -13.5 NA NA NA
2h64 1 P12643 85.71 1e-68 X-RAY
 2007-04-10 LYS A:73 A:73 162.0 0.81 T -70.4 -22.9 156.0 0.78 0.03 A:P12643:0.03
 HOH
 2.885
 CE
 O
1es7 1 P12643 87.5 2e-68 X-RAY
 2000-10-07 LYS A:75 A:73 182.0 0.91 T -68.8 -28.9 178.0 0.89 0.02 C:P12643:0.02
 HOH
 9.485
 N
 O
LYS C:75 C:573 182.0 0.91 T -69.6 -27.2 177.0 0.885 0.025 A:P12643:0.025
 HOH
 9.357
 N
 O
2qj9 1 P12643 87.5 2e-68 X-RAY
 2008-01-15 LYS A:75 B:73 186.0 0.93 T -70.7 -10.4 177.0 0.885 0.045 B:P12643:0.045
 HOH
 3.367
 O
 O
LYS B:75 A:73 176.0 0.88 T -63.6 -12.1 168.0 0.84 0.04 A:P12643:0.04
 HOH
 4.936
 O
 O
2qja 1 P12643 87.5 2e-68 X-RAY
 2008-01-15 LYS A:75 A:73 185.0 0.925 T -73.0 -6.9 179.0 0.895 0.03 B:P12643:0.03
 HOH
 8.908
 N
 O
LYS B:75 B:73 179.0 0.895 T -75.1 -17.3 173.0 0.865 0.03 A:P12643:0.03
 HOH
 5.322
 N
 O
2qjb 1 P12643 87.5 2e-68 X-RAY
 2008-01-15 LYS A:75 A:73 182.0 0.91 T -70.2 -8.6 175.0 0.875 0.035 B:P12643:0.035
 HOH
 9.311
 O
 O
LYS B:75 B:73 182.0 0.91 T -66.4 -21.3 176.0 0.88 0.03 A:P12643:0.03
 HOH
 9.756
 N
 O
1rew 1 P12643 87.5 4e-68 X-RAY
 2004-05-04 LYS A:73 A:73 178.0 0.89 T -64.5 -24.8 173.0 0.865 0.025 B:P12643:0.025
 HOH
 2.597
 NZ
 O
LYS B:73 B:73 185.0 0.925 T -68.1 -17.6 180.0 0.9 0.025 A:P12643:0.025
 HOH
 7.014
 CB
 O
2goo 1 P12643 87.5 4e-68 X-RAY
 2006-05-09 LYS A:73 A:73 184.0 0.92 T -61.9 -30.4 184.0 0.92 0.0 HOH
 2.856
 O
 O
LYS D:73 D:73 184.0 0.92 T -71.1 -27.5 184.0 0.92 0.0 HOH
 4.712
 N
 O
2h62 1 P12643 87.5 4e-68 X-RAY
 2007-04-10 LYS A:73 A:73 187.0 0.935 T -76.0 -18.2 180.0 0.9 0.035 B:P12643:0.035
 HOH
 3.958
 CD
 O
LYS B:73 B:73 178.0 0.89 T -67.6 -22.0 173.0 0.865 0.025 A:P12643:0.025
 HOH
 3.536
 CB
 O
3bmp 1 P12643 87.5 4e-68 X-RAY
 2000-03-12 LYS A:73 A:73 173.0 0.865 T -71.4 -12.4 158.0 0.79 0.075 A:P12643:0.075
 HOH
 4.410
 CB
 O
4uhy 1 P12643 87.5 4e-68 X-RAY
 2015-05-06 LYS A:73 A:355 181.0 0.905 T -69.9 -22.5 176.0 0.88 0.025 B:P12643:0.025
LYS B:73 B:355 183.0 0.915 T -69.5 -22.1 179.0 0.895 0.02 A:P12643:0.02
4uhz 1 P12643 87.5 4e-68 X-RAY
 2015-05-06 LYS A:73 A:355 185.0 0.925 T -62.3 -29.3 185.0 0.925 0.0 SO4
 5.912
 N
 O1
4ui0 1 P12643 87.5 4e-68 X-RAY
 2015-05-06 LYS A:73 A:355 187.0 0.935 T -61.3 -19.0 182.0 0.91 0.025 B:P12643:0.025
 HOH
 9.361
 O
 O
LYS B:73 B:355 184.0 0.92 T -61.2 -19.6 179.0 0.895 0.025 A:P12643:0.025
4ui1 1 P12643 87.5 4e-68 X-RAY
 2015-05-06 LYS A:73 A:355 186.0 0.93 T -71.0 -26.5 186.0 0.93 0.0 HOH
 7.298
 CB
 O
LYS B:73 B:355 187.0 0.935 T -70.9 -26.3 NA NA NA
4ui2 2 P12643 87.5 4e-68 X-RAY
 2015-05-06 LYS B:73 B:355 183.0 0.915 T -60.5 -37.3 169.0 0.845 0.07 B:P12643:0.015
A:P97798:0.055
3bk3 1 P12643 85.71 5e-68 X-RAY
 2008-05-27 LYS A:73 A:73 180.0 0.9 T -84.1 -1.0 173.0 0.865 0.035 B:P12643:0.035
 HOH
 9.281
 O
 O
LYS B:73 B:73 178.0 0.89 T -84.8 -16.8 174.0 0.87 0.02 A:P12643:0.02
 HOH
 5.779
 CB
 O
1reu 1 P12643 90.2 5e-68 X-RAY
 2004-05-04 LYS A:62 A:73 191.0 0.955 S -64.6 -21.4 177.0 0.885 0.07 A:P12643:0.07
 HOH
 7.871
 CE
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p12644-f1 1 P12644 100.0 0.0 SER A:367 A:367 92.0 0.8 T -70.8 -19.9