Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 55895562 . G A CCDS9724.1:NM_199047.2:c.919Ctg>Ttg_NP_950248.1:p.307L>L Homo sapiens TATA-box binding protein like 2 (TBPL2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5fur 1 P20226 85.12 2e-126 EM
 2016-04-06 LEU A:270 A:270 6.0 0.035 H -60.8 -51.9 6.0 0.035 0.0 DT
DA
DG
 9.862
8.113
8.841
 CD1
CD1
CD1
 O3'
C4'
OP1
5iy6 16 P20226 85.12 2e-126 EM
 2016-05-18 LEU P:270 P:270 4.0 0.024 H -56.3 -31.0 4.0 0.024 0.0 DA
DG
 8.635
8.274
 CD1
CD1
 C5'
OP1
5iy7 16 P20226 85.12 2e-126 EM
 2016-05-18 LEU P:270 P:270 8.0 0.047 H -96.4 -36.5 8.0 0.047 0.0 DA
DG
 9.363
9.533
 CD1
CD1
 C5'
OP1
5iy8 16 P20226 85.12 2e-126 EM
 2016-05-18 LEU P:270 P:270 10.0 0.059 H -58.6 -33.3 10.0 0.059 0.0 DA
 9.561
 CD2
 C5'
5iy9 16 P20226 85.12 2e-126 EM
 2016-05-18 LEU P:270 P:270 10.0 0.059 H -95.5 -34.2 10.0 0.059 0.0 DA
DG
 9.948
9.774
 CD1
CD1
 C4'
C5'
5iya 16 P20226 85.12 2e-126 EM
 2016-05-18 LEU P:270 P:270 4.0 0.024 H -56.3 -31.0 4.0 0.024 0.0 DA
DG
 8.705
8.356
 CD1
CD1
 C5'
OP1
5iyb 16 P20226 85.12 2e-126 EM
 2016-05-18 LEU P:270 P:270 8.0 0.047 H -96.4 -36.5 7.0 0.041 0.006 M:Q00403:0.006
 DA
DG
 9.363
9.532
 CD1
CD1
 C5'
OP1
5iyc 16 P20226 85.12 2e-126 EM
 2016-05-18 LEU P:270 P:270 9.0 0.053 H -58.6 -33.3 9.0 0.053 0.0 DA
 9.561
 CD2
 C5'
5iyd 16 P20226 85.12 2e-126 EM
 2016-05-18 LEU P:270 P:270 11.0 0.065 H -95.5 -34.2 11.0 0.065 0.0 DA
DG
 9.949
9.775
 CD1
CD1
 C4'
C5'
6mzd 11 P20226 85.12 2e-126 EM
 2018-11-28 LEU K:270 T:270 16.0 0.094 H -77.1 -39.4 0.0 0.0 0.094 H:Q15544:0.094
6mzl 15 P20226 85.12 2e-126 EM
 2018-11-28 LEU T:270 T:270 16.0 0.094 H -77.1 -39.4 0.0 0.0 0.094 P:Q15544:0.094
6mzm 12 P20226 85.12 2e-126 EM
 2018-11-28 LEU L:270 T:270 6.0 0.035 H -70.8 -39.5 6.0 0.035 0.0 DA
DG
 8.425
8.601
 CD1
CD1
 C4'
OP1
6o9l 16 P20226 85.12 2e-126 EM
 2019-05-29 LEU P:270 P:270 9.0 0.053 H -76.5 -13.5 9.0 0.053 0.0 DA
 9.982
 CD1
 C5'
7edx 12 P20226 85.12 2e-126 EM
 2021-05-05 LEU L:270 P:270 13.0 0.076 H -64.1 -39.4 13.0 0.076 0.0 DA
DG
 7.815
8.640
 CD1
CD1
 C5'
C5'
7eg7 12 P20226 85.12 2e-126 EM
 2021-05-05 LEU L:270 P:270 13.0 0.076 H -64.2 -39.5 13.0 0.076 0.0
7eg8 12 P20226 85.12 2e-126 EM
 2021-05-05 LEU L:270 P:270 12.0 0.071 H -64.1 -39.5 12.0 0.071 0.0 DA
DG
 8.524
9.665
 CD1
CD1
 O4'
C5'
7eg9 12 P20226 85.12 2e-126 EM
 2021-05-05 LEU L:270 P:270 12.0 0.071 H -64.2 -39.4 12.0 0.071 0.0 DA
DT
DA
 8.609
7.313
7.193
 CD1
CD1
CD1
 C2
O3'
OP1
7ega 12 P20226 85.12 2e-126 EM
 2021-05-05 LEU L:270 P:270 8.0 0.047 H -64.0 -39.7 8.0 0.047 0.0 DA
DG
 8.524
9.665
 CD1
CD1
 O4'
C5'
7egb 22 P20226 85.12 2e-126 EM
 2021-05-05 LEU V:270 P:270 3.0 0.018 H -85.4 -15.7 3.0 0.018 0.0 DA
DG
 9.261
9.055
 CD1
CD1
 O3'
OP1
7egc 22 P20226 85.12 2e-126 EM
 2021-05-12 LEU V:270 P:270 12.0 0.071 H -64.2 -39.6 12.0 0.071 0.0 DT
DA
DG
 9.821
9.307
9.213
 CD1
CD1
CD1
 C2'
O3'
C5'
7egd 12 P20226 85.12 2e-126 EM
 2021-05-12 LEU L:270 P:270 5.0 0.029 H -85.4 -15.8 4.0 0.024 0.005 V:Q15544:0.006
 DA
 9.411
 CD1
 OP1
7ege 11 P20226 85.12 2e-126 EM
 2021-05-12 LEU K:270 P:270 5.0 0.029 H -85.3 -15.7 0.0 0.0 0.029 R:Q15544:0.018
M:O00268:0.012
7egf 1 P20226 85.12 2e-126 EM
 2021-05-05 LEU A:270 P:270 4.0 0.024 H -85.4 -15.7 0.0 0.0 0.024 C:O00268:0.006
H:Q15544:0.012
7egi 12 P20226 85.12 2e-126 EM
 2021-05-12 LEU L:270 P:270 5.0 0.029 H -85.5 -15.6 1.0 0.006 0.023 T:Q15544:0.018
O:O00268:0.012
7egj 12 P20226 85.12 2e-126 EM
 2021-05-12 LEU L:270 P:270 4.0 0.024 H -85.4 -15.7 4.0 0.024 0.0
7ena 5 P20226 85.12 2e-126 EM
 2021-05-26 LEU E:270 DP:270 23.0 0.135 -102.8 4.9 23.0 0.135 0.0
7enc 49 P20226 85.12 2e-126 EM
 2021-05-26 LEU CB:270 DP:270 22.0 0.129 H -65.3 -39.7 14.0 0.082 0.047 EB:Q00403:0.047
 DA
DG
DG
 8.153
8.461
9.119
 CD1
CD1
CD1
 O3'
OP1
OP1
7lbm 20 P20226 85.12 2e-126 EM
 2021-03-24 LEU T:270 P:270 1.0 0.006 H -95.1 -15.2 1.0 0.006 0.0 DA
DG
 9.430
9.296
 CD2
CD1
 C4'
OP1
7nvr 25 P20226 85.12 2e-126 EM
 2021-05-05 LEU Y:270 O:270 0.0 0.0 H -59.9 -29.2 0.0 0.0 0.0 DA
DG
 8.329
8.708
 CD1
CD1
 C4'
C5'
7nvs 15 P20226 85.12 2e-126 EM
 2021-05-05 LEU O:270 O:270 0.0 0.0 H -64.5 -33.7 0.0 0.0 0.0 DA
DG
 8.231
8.677
 CD1
CD1
 C4'
C5'
7nvt 15 P20226 85.12 2e-126 EM
 2021-05-05 LEU O:270 O:270 0.0 0.0 H -63.0 -30.6 0.0 0.0 0.0 DA
DG
 8.305
8.837
 CD1
CD1
 C4'
C5'
7nvu 15 P20226 85.12 2e-126 EM
 2021-05-05 LEU O:270 O:270 0.0 0.0 H -64.3 -30.0 0.0 0.0 0.0 DT
DA
DG
 9.934
8.232
8.836
 CD1
CD1
CD1
 C2'
C4'
C5'
7nvy 23 P20226 85.12 2e-126 EM
 2021-05-05 LEU W:270 O:270 0.0 0.0 H -63.6 -32.5 0.0 0.0 0.0 DA
DG
 8.178
8.593
 CD1
CD1
 C4'
C5'
7nvz 23 P20226 85.12 2e-126 EM
 2021-05-05 LEU W:270 O:270 0.0 0.0 H -62.5 -30.4 0.0 0.0 0.0 DA
DG
 8.255
8.778
 CD1
CD1
 C4'
C5'
7nw0 23 P20226 85.12 2e-126 EM
 2021-05-05 LEU W:270 O:270 0.0 0.0 H -64.9 -30.3 0.0 0.0 0.0 DT
DA
DG
 9.888
8.168
8.809
 CD1
CD1
CD1
 C2'
C4'
C5'
1jfi 5 P20226 92.86 8e-123 X-RAY
 2001-07-11 LEU E:116 C:470 0.0 0.0 H -49.6 -34.4 0.0 0.0 0.0 DA
DG
HOH
 8.406
8.910
6.965
 CD1
CD1
CD1
 C4'
O5'
O
1tgh 2 P20226 92.86 1e-122 X-RAY
 1996-08-01 LEU C:116 A:266 0.0 0.0 H -48.6 -43.5 0.0 0.0 0.0 DT
DA
DC
 9.992
8.010
7.984
 CD1
CD1
CD1
 O3'
C4'
OP1
1nvp 3 P20226 94.38 1e-122 X-RAY
 2003-10-21 LEU C:112 A:270 6.0 0.035 H -60.5 -52.2 6.0 0.035 0.0 DA
DG
HOH
 8.307
8.963
4.086
 CD1
CD1
CD1
 C4'
OP1
O
1c9b 4 P20226 94.38 2e-122 X-RAY
 2000-01-10 LEU L:113 B:270 0.0 0.0 H -53.3 -35.3 0.0 0.0 0.0 DT
DA
DG
HOH
 9.918
8.421
9.067
3.918
 CD1
CD1
CD1
CD1
 O3'
C5'
C5'
O
LEU N:113 F:270 0.0 0.0 H -56.2 -34.5 NA NA NA
LEU P:113 J:270 2.0 0.012 H -58.0 -34.0 NA NA NA
LEU R:113 N:270 1.0 0.006 H -55.0 -35.4 NA NA NA
LEU T:113 R:270 0.0 0.0 H -55.2 -37.4 NA NA NA
5n9g 2 P20226 94.38 2e-122 X-RAY
 2017-06-14 LEU B:131 B:270 6.0 0.035 H -53.6 -39.2 0.0 0.0 0.035 A:Q9HAW0:0.035
 A
A
G
HOH
 9.840
7.735
8.474
5.735
 CD1
CD1
CD1
N
 C2'
C4'
C5'
O
LEU G:131 G:270 6.0 0.035 H -53.3 -39.4 NA NA NA
4roc 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 LEU B:114 B:270 4.0 0.024 H -55.1 -36.8 0.0 0.0 0.024 A:Q9HAW0:0.024
 DA
DA
DG
HOH
 9.927
7.852
8.654
3.969
 CD1
CD1
CD1
CD1
 C2'
C4'
C5'
O
4rod 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 LEU B:114 B:270 3.0 0.018 H -55.4 -36.5 0.0 0.0 0.018 A:Q9HAW0:0.018
 DA
DG
DG
HOH
 9.963
7.909
8.731
3.975
 CD1
CD1
CD1
CD1
 C2'
C4'
C5'
O
4roe 2 P20226 94.38 3e-122 X-RAY
 2015-12-30 LEU B:114 B:270 4.0 0.024 H -60.6 -33.0 0.0 0.0 0.024 A:Q9HAW0:0.024
 DA
DG
DT
HOH
 9.846
7.747
8.712
3.664
 CD1
CD1
CD1
CD1
 C2'
C4'
C5'
O
1cdw 3 P20226 93.82 2e-121 X-RAY
 1996-12-23 LEU C:112 A:266 0.0 0.0 H -55.2 -35.1 0.0 0.0 0.0 DT
DA
DG
HOH
 9.972
8.081
6.856
4.134
 CD1
CD1
CD1
CD1
 O3'
C4'
OP1
O
1vtl 3 P28147 80.9 2e-104 X-RAY
 2011-07-13 LEU E:118 E:130 3.0 0.018 H -51.5 -45.2 3.0 0.018 0.0 DT
DA
DG
 9.968
8.114
7.877
 CD1
CD1
CD1
 O3'
C4'
OP1
LEU F:118 F:130 4.0 0.024 H -58.9 -33.9 NA NA NA
1vto 3 P28147 80.9 3e-104 X-RAY
 2011-07-13 LEU E:120 A:130 2.0 0.012 H -56.2 -42.2 2.0 0.012 0.0 DA
DG
HOH
 8.133
8.628
2.253
 CD1
CD1
H
 C4'
OP1
H1
LEU F:120 B:1130 3.0 0.018 H -54.7 -37.8 NA NA NA
1qn3 1 P28147 80.9 3e-104 X-RAY
 2000-02-06 LEU A:130 A:130 4.0 0.024 H -59.3 -46.3 4.0 0.024 0.0 DA
DG
HOH
 7.924
8.097
3.286
 CD1
CD1
N
 C4'
OP1
O
LEU B:130 B:130 4.0 0.024 H -56.6 -42.5 NA NA NA
1qn4 1 P28147 80.9 3e-104 X-RAY
 2000-02-06 LEU A:130 A:130 4.0 0.024 H -58.5 -46.7 4.0 0.024 0.0 DT
DA
DG
HOH
 9.969
7.881
8.178
3.226
 CD1
CD1
CD1
N
 O3'
C4'
OP1
O
LEU B:130 B:130 4.0 0.024 H -60.1 -41.2 NA NA NA
1qn5 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LEU A:130 A:130 3.0 0.018 H -56.9 -45.7 3.0 0.018 0.0 DT
DA
DG
HOH
 9.888
7.992
7.979
3.275
 CD1
CD1
CD1
N
 O3'
C4'
OP1
O
LEU B:130 B:130 3.0 0.018 H -53.4 -40.2 NA NA NA
1qn6 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LEU A:130 A:130 3.0 0.018 H -60.1 -41.8 3.0 0.018 0.0 DT
DA
DG
HOH
 9.914
7.875
8.387
3.298
 CD1
CD1
CD1
N
 C2'
C4'
OP1
O
LEU B:130 B:130 2.0 0.012 H -58.6 -34.8 NA NA NA
1qn7 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LEU A:130 A:130 4.0 0.024 H -52.7 -39.5 4.0 0.024 0.0 DT
DA
DG
HOH
 9.764
7.983
8.401
3.372
 CD1
CD1
CD1
N
 O3'
C4'
OP1
O
LEU B:130 B:130 4.0 0.024 H -60.3 -33.2 NA NA NA
1qn8 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LEU A:130 A:130 5.0 0.029 H -58.5 -41.3 5.0 0.029 0.0 DT
DA
DG
HOH
 9.866
7.899
7.008
3.399
 CD1
CD1
CD1
N
 O3'
C4'
OP1
O
LEU B:130 B:130 4.0 0.024 H -61.8 -35.9 NA NA NA
1qn9 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LEU A:130 A:130 4.0 0.024 H -55.4 -35.8 4.0 0.024 0.0 DT
DA
DG
HOH
 9.814
7.848
8.172
3.378
 CD1
CD1
CD1
N
 O3'
C4'
OP1
O
LEU B:130 B:130 4.0 0.024 H -59.1 -40.8 NA NA NA
1qna 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LEU A:130 A:130 2.0 0.012 H -56.5 -48.3 2.0 0.012 0.0 DA
DA
DG
HOH
 9.812
7.278
7.520
3.210
 CD1
CD1
CD1
N
 C2'
C4'
OP1
O
LEU B:130 B:130 4.0 0.024 H -61.0 -40.3 NA NA NA
1qnb 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LEU A:130 A:130 2.0 0.012 H -54.5 -41.2 2.0 0.012 0.0 DA
DG
HOH
 8.029
8.272
3.291
 CD1
CD1
N
 C4'
OP1
O
LEU B:130 B:130 4.0 0.024 H -59.1 -40.4 NA NA NA
1qnc 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LEU A:130 A:130 4.0 0.024 H -63.6 -34.4 4.0 0.024 0.0 DT
DT
DG
HOH
 9.827
7.270
7.183
3.342
 CD1
CD1
CD1
N
 O3'
C4'
OP1
O
LEU B:130 B:130 6.0 0.035 H -54.3 -35.6 NA NA NA
1qne 1 P28147 80.9 3e-104 X-RAY
 2000-02-07 LEU A:130 A:130 2.0 0.012 H -56.5 -42.3 2.0 0.012 0.0 DA
DG
HOH
 8.121
8.520
3.441
 CD1
CD1
N
 C4'
OP1
O
LEU B:130 B:130 3.0 0.018 H -54.8 -38.8 NA NA NA
1vok 1 P28147 80.9 3e-104 X-RAY
 1996-11-08 LEU A:130 A:130 4.0 0.024 H -61.6 -34.5 4.0 0.024 0.0 HOH
 3.257
 N
 O
LEU B:130 B:130 6.0 0.035 H -63.7 -36.3 NA NA NA
1vol 4 P28147 80.9 3e-104 X-RAY
 1996-11-08 LEU D:130 B:130 2.0 0.012 H -52.6 -46.2 2.0 0.012 0.0 DA
DG
 8.382
8.814
 CD1
CD1
 C5'
C5'
6ueo 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 LEU A:149 A:130 0.0 0.0 H -62.7 -34.8 0.0 0.0 0.0 DT
DA
DG
HOH
 9.844
8.061
8.602
3.408
 CD1
CD1
CD1
N
 C2'
C4'
C5'
O
LEU D:149 D:130 2.0 0.012 H -61.5 -42.2 NA NA NA
LEU G:149 G:130 3.0 0.018 H -61.8 -41.0 NA NA NA
LEU J:149 J:130 1.0 0.006 H -63.7 -38.6 NA NA NA
6uep 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 LEU A:149 B:130 0.0 0.0 H -62.4 -33.6 0.0 0.0 0.0 DT
DA
DG
HOH
 9.873
8.144
8.436
3.228
 CD1
CD1
CD1
N
 O3'
C4'
OP1
O
LEU D:149 A:130 0.0 0.0 H -61.6 -34.3 NA NA NA
6ueq 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 LEU A:149 B:130 1.0 0.006 H -73.5 -39.2 1.0 0.006 0.0 DT
DA
DG
HOH
 9.971
8.080
7.763
3.990
 CD1
CD1
CD1
CD1
 O3'
C4'
OP1
O
6uer 1 P28147 80.9 8e-104 X-RAY
 2020-09-02 LEU A:149 A:130 0.0 0.0 H -69.1 -39.1 0.0 0.0 0.0 DA
DG
 8.186
8.708
 CD1
CD1
 C4'
C5'
LEU D:149 B:130 4.0 0.024 H -63.5 -20.1 NA NA NA
6njq 1 P28147 80.9 8e-104 X-RAY
 2019-10-30 LEU A:150 B:130 3.0 0.018 H -62.0 -33.2 3.0 0.018 0.0 DT
DA
DG
 9.815
8.243
7.459
 CD1
CD1
CD1
 O3'
C5'
OP1
LEU D:150 A:130 2.0 0.012 H -56.0 -38.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q6sj96-f1 1 Q6SJ96 100.0 0.0 LEU A:307 A:307 0.0 0.0 H -58.6 -31.4
af-p20226-f1 1 P20226 85.12 8e-127 LEU A:270 A:270 0.0 0.0 H -63.9 -32.5