Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 65470970 . A C CCDS9769.1:NM_002028.3:c.148Aaa>Caa_NP_002019.1:p.50K>Q Homo sapiens farnesyltransferase, CAAX box, beta (FNTB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1jcq 2 P49356 100.0 0.0 X-RAY
 2001-11-02 LYS B:50 B:50 126.0 0.63 H -65.3 -43.6 126.0 0.63 0.0 HOH
 2.714
 O
 O
1ld7 2 P49356 100.0 0.0 X-RAY
 2002-06-19 LYS B:50 B:550 126.0 0.63 H -62.5 -45.5 126.0 0.63 0.0 HOH
 2.948
 O
 O
1ld8 2 P49356 100.0 0.0 X-RAY
 2002-06-19 LYS B:50 B:550 131.0 0.655 H -64.7 -42.5 131.0 0.655 0.0 HOH
 2.711
 O
 O
1mzc 2 P49356 100.0 0.0 X-RAY
 2003-07-08 LYS B:50 B:550 130.0 0.65 H -60.3 -45.3 130.0 0.65 0.0 HOH
 2.692
 O
 O
1s63 2 P49356 100.0 0.0 X-RAY
 2004-07-27 LYS B:50 B:50 121.0 0.605 H -62.2 -42.3 121.0 0.605 0.0 HOH
 2.686
 O
 O
1sa4 2 P49356 100.0 0.0 X-RAY
 2004-06-08 LYS B:50 B:50 125.0 0.625 H -65.2 -41.5 125.0 0.625 0.0 HOH
 2.679
 O
 O
1tn6 2 P49356 100.0 0.0 X-RAY
 2004-11-02 LYS B:50 B:550 128.0 0.64 H -64.7 -40.8 128.0 0.64 0.0 HOH
 2.670
 O
 O
2f0y 2 P49356 100.0 0.0 X-RAY
 2006-11-14 LYS B:50 B:50 123.0 0.615 H -71.0 -33.9 123.0 0.615 0.0 HOH
 3.008
 NZ
 O
2h6f 2 P49356 100.0 0.0 X-RAY
 2006-08-29 LYS B:50 B:550 119.0 0.595 H -63.0 -41.9 119.0 0.595 0.0 HOH
 2.717
 O
 O
2iej 2 P49356 100.0 0.0 X-RAY
 2007-01-23 LYS B:50 B:550 125.0 0.625 H -62.2 -43.1 125.0 0.625 0.0 HOH
 2.604
 O
 O
3e37 2 P49356 100.0 0.0 X-RAY
 2009-03-10 LYS B:50 B:52 125.0 0.625 H -61.4 -44.5 125.0 0.625 0.0 HOH
 2.676
 O
 O
2h6h 2 P49356 99.77 0.0 X-RAY
 2006-08-29 LYS B:50 B:550 121.0 0.605 H -63.2 -41.1 121.0 0.605 0.0 HOH
 2.662
 O
 O
2h6g 2 P49356 99.77 0.0 X-RAY
 2006-08-29 LYS B:50 B:550 123.0 0.615 H -65.2 -40.7 123.0 0.615 0.0 HOH
 2.637
 O
 O
2h6i 2 P49356 99.54 0.0 X-RAY
 2006-08-29 LYS B:50 B:550 119.0 0.595 H -60.7 -47.2 119.0 0.595 0.0 HOH
 3.101
 O
 O
1o1r 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 LYS B:50 B:50 120.0 0.6 H -61.3 -42.2 120.0 0.6 0.0 HOH
 2.902
 O
 O
1o1s 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 LYS B:50 B:50 122.0 0.61 H -62.0 -39.4 122.0 0.61 0.0 HOH
 2.705
 O
 O
1o1t 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 LYS B:50 B:50 121.0 0.605 H -60.1 -39.9 121.0 0.605 0.0 HOH
 2.750
 O
 O
3eu5 2 Q02293 98.12 0.0 X-RAY
 2009-07-07 LYS B:50 B:50 114.0 0.57 H -52.4 -52.7 114.0 0.57 0.0 HOH
 9.160
 NZ
 O
4gtm 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 LYS B:50 B:50 101.0 0.505 H -55.8 -47.6 101.0 0.505 0.0 HOH
 2.624
 O
 O
4gto 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 LYS B:50 B:50 118.0 0.59 H -54.2 -51.2 118.0 0.59 0.0 HOH
 2.632
 O
 O
4gtp 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 LYS B:50 B:50 105.0 0.525 H -47.3 -48.4 105.0 0.525 0.0 HOH
 2.704
 O
 O
4gtq 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 LYS B:50 B:50 97.0 0.485 H -53.0 -47.0 97.0 0.485 0.0 HOH
 2.745
 O
 O
4gtr 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 LYS B:50 B:50 109.0 0.545 H -57.9 -47.6 109.0 0.545 0.0 HOH
 2.713
 O
 O
3pz4 2 Q02293 98.11 0.0 X-RAY
 2011-05-11 LYS B:49 B:50 113.0 0.565 H -50.8 -42.9 113.0 0.565 0.0 HOH
 2.553
 O
 O
1d8d 2 Q02293 96.57 0.0 X-RAY
 2000-02-09 LYS B:50 B:50 125.0 0.625 H -59.4 -44.7 125.0 0.625 0.0 HOH
 2.691
 O
 O
1d8e 2 Q02293 96.57 0.0 X-RAY
 2000-03-20 LYS B:50 B:50 125.0 0.625 H -54.2 -46.3 125.0 0.625 0.0 HOH
 7.341
 C
 O
1fpp 1 Q02293 96.57 0.0 X-RAY
 1999-06-08 LYS A:50 B:50 111.0 0.555 H -75.6 -36.0 111.0 0.555 0.0
1ft1 2 Q02293 96.57 0.0 X-RAY
 1998-03-18 LYS B:50 B:50 93.0 0.465 H -54.4 -48.2 93.0 0.465 0.0 HOH
 3.117
 O
 O
1jcr 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 LYS B:50 B:50 122.0 0.61 H -56.8 -45.1 122.0 0.61 0.0 HOH
 2.672
 O
 O
1jcs 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 LYS B:50 B:50 124.0 0.62 H -59.8 -45.7 124.0 0.62 0.0 HOH
 2.697
 O
 O
1kzo 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 LYS B:50 B:50 127.0 0.635 H -56.5 -44.7 127.0 0.635 0.0 HOH
 2.694
 O
 O
1kzp 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 LYS B:50 B:50 122.0 0.61 H -58.9 -45.1 122.0 0.61 0.0 HOH
 2.597
 O
 O
1o5m 2 Q02293 96.57 0.0 X-RAY
 2003-10-21 LYS B:50 B:50 121.0 0.605 H -63.3 -40.8 121.0 0.605 0.0 HOH
 2.994
 O
 O
1qbq 2 Q02293 96.57 0.0 X-RAY
 1999-06-18 LYS B:50 B:50 103.0 0.515 H -71.0 -45.9 103.0 0.515 0.0 HOH
 3.537
 CB
 O
1sa5 2 Q02293 96.57 0.0 X-RAY
 2004-06-08 LYS B:50 B:50 121.0 0.605 H -54.7 -49.3 121.0 0.605 0.0 HOH
 2.702
 O
 O
1tn7 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 LYS B:50 B:550 120.0 0.6 H -59.6 -44.9 120.0 0.6 0.0 HOH
 2.729
 O
 O
1tn8 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 LYS B:50 B:550 119.0 0.595 H -58.3 -47.4 119.0 0.595 0.0 HOH
 2.692
 O
 O
3dpy 2 Q02293 96.57 0.0 X-RAY
 2008-09-30 LYS B:50 B:50 128.0 0.64 H -63.2 -47.0 128.0 0.64 0.0 HOH
 3.896
 NZ
 O
3e30 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 LYS B:50 B:50 121.0 0.605 H -56.7 -46.5 121.0 0.605 0.0 HOH
 2.682
 O
 O
3e32 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 LYS B:50 B:50 118.0 0.59 H -56.1 -47.3 118.0 0.59 0.0 HOH
 2.702
 O
 O
3e33 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 LYS B:50 B:50 122.0 0.61 H -63.4 -42.5 122.0 0.61 0.0 HOH
 2.636
 O
 O
3e34 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 LYS B:50 B:50 121.0 0.605 H -60.7 -46.4 121.0 0.605 0.0 HOH
 3.579
 CB
 O
3ksl 2 Q02293 96.57 0.0 X-RAY
 2009-12-22 LYS B:50 B:50 108.0 0.54 H -62.2 -44.6 108.0 0.54 0.0 HOH
 2.731
 O
 O
3ksq 2 Q02293 96.57 0.0 X-RAY
 2010-01-26 LYS B:50 B:50 120.0 0.6 H -60.6 -46.4 120.0 0.6 0.0 HOH
 2.691
 O
 O
7rn5 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 LYS B:50 B:50 119.0 0.595 H -60.2 -44.7 119.0 0.595 0.0 HOH
 2.738
 O
 O
7rni 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 LYS B:50 B:50 122.0 0.61 H -60.8 -47.0 122.0 0.61 0.0 HOH
 2.653
 O
 O
2zir 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 LYS B:53 B:50 122.0 0.61 H -61.6 -44.3 122.0 0.61 0.0 GOL
HOH
 8.796
3.466
 CD
CB
 O1
O
2zis 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 LYS B:53 B:50 124.0 0.62 H -59.1 -47.5 124.0 0.62 0.0 HOH
 2.716
 O
 O
3euv 2 Q02293 97.65 0.0 X-RAY
 2009-07-07 LYS B:50 B:50 113.0 0.565 H -63.8 -45.1 113.0 0.565 0.0 HOH
 5.767
 O
 O
1n95 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 LYS B:29 B:50 105.0 0.525 H -71.3 -44.7 105.0 0.525 0.0
1n9a 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 LYS B:29 B:50 106.0 0.53 H -70.0 -45.5 106.0 0.53 0.0
1ni1 2 Q02293 98.26 0.0 X-RAY
 2004-04-06 LYS B:29 B:50 112.0 0.56 H -56.0 -42.4 112.0 0.56 0.0
1nl4 2 Q02293 98.25 0.0 X-RAY
 2003-02-11 LYS B:28 B:50 110.0 0.55 H -54.6 -52.0 110.0 0.55 0.0
2bed 2 Q02293 98.25 0.0 X-RAY
 2006-08-08 LYS B:28 B:50 105.0 0.525 H -57.9 -49.2 105.0 0.525 0.0 HOH
 3.618
 CB
 O
2r2l 2 Q02293 98.25 0.0 X-RAY
 2008-03-11 LYS B:28 B:50 124.0 0.62 H -60.4 -43.8 124.0 0.62 0.0 HOH
 2.857
 O
 O
1ft2 2 Q02293 98.25 0.0 X-RAY
 1998-11-04 LYS B:29 B:50 100.0 0.5 H -49.6 -55.1 100.0 0.5 0.0
1n94 2 Q02293 98.24 0.0 X-RAY
 2003-01-07 LYS B:29 B:50 100.0 0.5 H -54.7 -41.2 100.0 0.5 0.0
1x81 2 Q02293 98.24 0.0 X-RAY
 2004-12-21 LYS B:29 B:50 98.0 0.49 H -58.8 -43.1 98.0 0.49 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p49356-f1 1 P49356 100.0 0.0 LYS A:50 A:50 119.0 0.595 H -61.0 -41.8