Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 65482425 . T A CCDS9769.1:NM_002028.3:c.365gTg>gAg_NP_002019.1:p.122V>E Homo sapiens farnesyltransferase, CAAX box, beta (FNTB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1jcq 2 P49356 100.0 0.0 X-RAY
 2001-11-02 VAL B:122 B:122 25.0 0.161 H -69.0 -41.6 23.0 0.148 0.013 A:P49354:0.013
 HOH
 4.907
 CG2
 O
1ld7 2 P49356 100.0 0.0 X-RAY
 2002-06-19 VAL B:122 B:622 22.0 0.142 H -66.2 -42.4 22.0 0.142 0.0 HOH
 4.221
 CG2
 O
1ld8 2 P49356 100.0 0.0 X-RAY
 2002-06-19 VAL B:122 B:622 24.0 0.155 H -62.3 -42.1 22.0 0.142 0.013 A:P49354:0.013
 HOH
 3.744
 CG2
 O
1mzc 2 P49356 100.0 0.0 X-RAY
 2003-07-08 VAL B:122 B:622 22.0 0.142 H -65.0 -43.1 22.0 0.142 0.0 HOH
 3.879
 CG2
 O
1s63 2 P49356 100.0 0.0 X-RAY
 2004-07-27 VAL B:122 B:122 23.0 0.148 H -64.1 -42.6 22.0 0.142 0.006 A:P49354:0.006
 HOH
 3.657
 CG2
 O
1sa4 2 P49356 100.0 0.0 X-RAY
 2004-06-08 VAL B:122 B:122 26.0 0.168 H -65.8 -44.2 24.0 0.155 0.013 A:P49354:0.013
 HOH
 3.713
 CG2
 O
1tn6 2 P49356 100.0 0.0 X-RAY
 2004-11-02 VAL B:122 B:622 19.0 0.123 H -63.3 -41.3 17.0 0.11 0.013 A:P49354:0.013
 HOH
 3.796
 CG2
 O
2f0y 2 P49356 100.0 0.0 X-RAY
 2006-11-14 VAL B:122 B:122 20.0 0.129 H -59.6 -56.0 20.0 0.129 0.0 HOH
 3.915
 CG2
 O
2h6f 2 P49356 100.0 0.0 X-RAY
 2006-08-29 VAL B:122 B:622 25.0 0.161 H -64.4 -39.4 23.0 0.148 0.013 A:P49354:0.013
 HOH
 3.856
 CG2
 O
2iej 2 P49356 100.0 0.0 X-RAY
 2007-01-23 VAL B:122 B:622 23.0 0.148 H -61.5 -46.7 22.0 0.142 0.006 A:P49354:0.006
 HOH
 3.601
 CG2
 O
3e37 2 P49356 100.0 0.0 X-RAY
 2009-03-10 VAL B:122 B:124 23.0 0.148 H -62.2 -45.7 22.0 0.142 0.006 A:P49354:0.006
 HOH
 3.624
 CG2
 O
2h6h 2 P49356 99.77 0.0 X-RAY
 2006-08-29 VAL B:122 B:622 25.0 0.161 H -64.6 -40.2 23.0 0.148 0.013 A:P49354:0.013
 HOH
 3.501
 CG2
 O
2h6g 2 P49356 99.77 0.0 X-RAY
 2006-08-29 VAL B:122 B:622 25.0 0.161 H -65.4 -38.6 23.0 0.148 0.013 A:P49354:0.013
 HOH
 3.888
 CG2
 O
2h6i 2 P49356 99.54 0.0 X-RAY
 2006-08-29 VAL B:122 B:622 23.0 0.148 H -63.7 -44.6 21.0 0.135 0.013 A:P49354:0.013
 HOH
 4.161
 CG2
 O
1o1r 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 VAL B:122 B:122 17.0 0.11 H -68.0 -47.3 16.0 0.103 0.007 A:Q04631:0.006
 HOH
 3.564
 CG2
 O
1o1s 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 VAL B:122 B:122 14.0 0.09 H -66.6 -49.5 13.0 0.084 0.006 A:Q04631:0.006
 HOH
 4.075
 CG1
 O
1o1t 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 VAL B:122 B:122 19.0 0.123 H -66.8 -48.6 18.0 0.116 0.007 A:Q04631:0.006
 HOH
 4.367
 CG2
 O
3eu5 2 Q02293 98.12 0.0 X-RAY
 2009-07-07 VAL B:122 B:122 24.0 0.155 H -69.5 -50.7 22.0 0.142 0.013 A:Q04631:0.013
 HOH
 3.890
 CG2
 O
4gtm 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 VAL B:122 B:122 19.0 0.123 H -72.6 -33.5 18.0 0.116 0.007 A:Q04631:0.006
 HOH
 3.830
 CG1
 O
4gto 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 VAL B:122 B:122 22.0 0.142 H -60.8 -46.4 20.0 0.129 0.013 A:Q04631:0.013
 HOH
 3.529
 CG2
 O
4gtp 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 VAL B:122 B:122 22.0 0.142 H -67.7 -53.5 22.0 0.142 0.0 HOH
 2.944
 CG1
 O
4gtq 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 VAL B:122 B:122 18.0 0.116 H -63.2 -47.1 16.0 0.103 0.013 A:Q04631:0.013
 HOH
 3.565
 CG2
 O
4gtr 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 VAL B:122 B:122 22.0 0.142 H -73.9 -39.9 21.0 0.135 0.007 A:Q04631:0.006
 HOH
 4.438
 CG1
 O
3pz4 2 Q02293 98.11 0.0 X-RAY
 2011-05-11 VAL B:121 B:122 20.0 0.129 H -69.3 -39.8 19.0 0.123 0.006 A:Q04631:0.006
 HOH
 3.947
 CG1
 O
1d8d 2 Q02293 96.57 0.0 X-RAY
 2000-02-09 VAL B:122 B:122 19.0 0.123 H -64.3 -52.2 19.0 0.123 0.0 HOH
 4.397
 CG2
 O
1d8e 2 Q02293 96.57 0.0 X-RAY
 2000-03-20 VAL B:122 B:122 20.0 0.129 H -53.9 -63.5 19.0 0.123 0.006 A:Q04631:0.006
 HOH
 9.496
 O
 O
1fpp 1 Q02293 96.57 0.0 X-RAY
 1999-06-08 VAL A:122 B:122 17.0 0.11 H -67.2 -37.5 16.0 0.103 0.007 B:Q04631:0.006
1ft1 2 Q02293 96.57 0.0 X-RAY
 1998-03-18 VAL B:122 B:122 17.0 0.11 H -68.6 -36.3 15.0 0.097 0.013 A:Q04631:0.013
 HOH
 3.847
 N
 O
1jcr 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 VAL B:122 B:122 19.0 0.123 H -62.8 -53.3 18.0 0.116 0.007 A:Q04631:0.006
 HOH
 4.235
 CG2
 O
1jcs 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 VAL B:122 B:122 19.0 0.123 H -64.7 -54.8 17.0 0.11 0.013 A:Q04631:0.013
 HOH
 4.284
 CG2
 O
1kzo 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 VAL B:122 B:122 18.0 0.116 H -62.7 -54.3 17.0 0.11 0.006 A:Q04631:0.006
 HOH
 4.079
 CG2
 O
1kzp 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 VAL B:122 B:122 20.0 0.129 H -61.8 -51.8 19.0 0.123 0.006 A:Q04631:0.006
 HOH
 4.272
 CG2
 O
1o5m 2 Q02293 96.57 0.0 X-RAY
 2003-10-21 VAL B:122 B:122 18.0 0.116 H -64.7 -47.5 16.0 0.103 0.013 A:Q04631:0.013
 HOH
 3.782
 CG2
 O
1qbq 2 Q02293 96.57 0.0 X-RAY
 1999-06-18 VAL B:122 B:122 36.0 0.232 H -66.9 -41.6 30.0 0.194 0.038 A:Q04631:0.039
 HOH
 3.799
 CG2
 O
1sa5 2 Q02293 96.57 0.0 X-RAY
 2004-06-08 VAL B:122 B:122 18.0 0.116 H -69.7 -50.6 16.0 0.103 0.013 A:Q04631:0.013
 HOH
 4.091
 CG2
 O
1tn7 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 VAL B:122 B:622 20.0 0.129 H -64.7 -54.5 19.0 0.123 0.006 A:Q04631:0.006
 HOH
 4.318
 CG2
 O
1tn8 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 VAL B:122 B:622 19.0 0.123 H -67.6 -58.9 17.0 0.11 0.013 A:Q04631:0.013
 HOH
 4.414
 CG2
 O
3dpy 2 Q02293 96.57 0.0 X-RAY
 2008-09-30 VAL B:122 B:122 23.0 0.148 H -66.9 -46.4 22.0 0.142 0.006 A:Q04631:0.006
3e30 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 VAL B:122 B:122 16.0 0.103 H -58.8 -55.1 14.0 0.09 0.013 A:Q04631:0.013
 HOH
 4.410
 CG2
 O
3e32 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 VAL B:122 B:122 20.0 0.129 H -59.1 -53.6 19.0 0.123 0.006 A:Q04631:0.006
 HOH
 4.410
 CG2
 O
3e33 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 VAL B:122 B:122 20.0 0.129 H -65.3 -49.1 19.0 0.123 0.006 A:Q04631:0.006
 HOH
 3.377
 CG2
 O
3e34 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 VAL B:122 B:122 19.0 0.123 H -60.8 -52.4 17.0 0.11 0.013 A:Q04631:0.013
 HOH
 3.447
 CG2
 O
3ksl 2 Q02293 96.57 0.0 X-RAY
 2009-12-22 VAL B:122 B:122 17.0 0.11 H -68.9 -50.8 16.0 0.103 0.007 A:Q5RKJ4:0.006
 HOH
 3.547
 CG2
 O
3ksq 2 Q02293 96.57 0.0 X-RAY
 2010-01-26 VAL B:122 B:122 14.0 0.09 H -63.8 -47.7 13.0 0.084 0.006 A:Q5RKJ4:0.006
 HOH
 4.687
 CG2
 O
7rn5 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 VAL B:122 B:122 40.0 0.258 H -67.6 -43.1 37.0 0.239 0.019 A:Q04631:0.019
 HOH
 3.428
 HG22
 O
7rni 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 VAL B:122 B:122 41.0 0.265 H -67.2 -41.8 38.0 0.245 0.02 A:Q04631:0.019
 HOH
 3.605
 HG11
 O
2zir 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 VAL B:125 B:122 18.0 0.116 H -72.3 -42.1 17.0 0.11 0.006 A:Q04631:0.006
 HOH
 3.671
 CG2
 O
2zis 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 VAL B:125 B:122 21.0 0.135 H -73.9 -43.8 19.0 0.123 0.012 A:Q04631:0.013
 HOH
 3.597
 CG2
 O
3euv 2 Q02293 97.65 0.0 X-RAY
 2009-07-07 VAL B:122 B:122 29.0 0.187 H -71.9 -50.3 27.0 0.174 0.013 A:Q04631:0.013
 HOH
 4.465
 CG2
 O
1n95 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 VAL B:101 B:122 36.0 0.232 H -68.4 -42.5 31.0 0.2 0.032 A:Q04631:0.032
1n9a 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 VAL B:101 B:122 36.0 0.232 H -69.1 -42.3 31.0 0.2 0.032 A:Q04631:0.032
1ni1 2 Q02293 98.26 0.0 X-RAY
 2004-04-06 VAL B:101 B:122 34.0 0.219 H -38.9 -44.4 31.0 0.2 0.019 A:Q04631:0.019
1nl4 2 Q02293 98.25 0.0 X-RAY
 2003-02-11 VAL B:100 B:122 35.0 0.226 H -64.9 -44.8 30.0 0.194 0.032 A:Q04631:0.032
2bed 2 Q02293 98.25 0.0 X-RAY
 2006-08-08 VAL B:100 B:122 10.0 0.065 H -57.9 -36.2 9.0 0.058 0.007 A:Q04631:0.006
 HOH
 6.528
 C
 O
2r2l 2 Q02293 98.25 0.0 X-RAY
 2008-03-11 VAL B:100 B:122 17.0 0.11 H -73.1 -44.2 15.0 0.097 0.013 A:Q5RKJ4:0.013
 HOH
 3.911
 CG2
 O
1ft2 2 Q02293 98.25 0.0 X-RAY
 1998-11-04 VAL B:101 B:122 18.0 0.116 H -62.2 -37.0 16.0 0.103 0.013 A:Q04631:0.013
1n94 2 Q02293 98.24 0.0 X-RAY
 2003-01-07 VAL B:101 B:122 16.0 0.103 H -70.7 -41.2 15.0 0.097 0.006 A:Q04631:0.006
1x81 2 Q02293 98.24 0.0 X-RAY
 2004-12-21 VAL B:101 B:122 20.0 0.129 H -51.1 -40.1 20.0 0.129 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p49356-f1 1 P49356 100.0 0.0 VAL A:122 A:122 16.0 0.103 H -65.4 -39.8