Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 65482430 . A C CCDS9769.1:NM_002028.3:c.370Aca>Cca_NP_002019.1:p.124T>P Homo sapiens farnesyltransferase, CAAX box, beta (FNTB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1jcq 2 P49356 100.0 0.0 X-RAY
 2001-11-02 THR B:124 B:124 43.0 0.307 H -64.0 -44.3 43.0 0.307 0.0 HOH
 7.034
 CG2
 O
1ld7 2 P49356 100.0 0.0 X-RAY
 2002-06-19 THR B:124 B:624 17.0 0.121 H -64.7 -36.7 17.0 0.121 0.0 HOH
 4.066
 CG2
 O
1ld8 2 P49356 100.0 0.0 X-RAY
 2002-06-19 THR B:124 B:624 21.0 0.15 H -66.4 -36.2 21.0 0.15 0.0 HOH
 4.066
 CG2
 O
1mzc 2 P49356 100.0 0.0 X-RAY
 2003-07-08 THR B:124 B:624 19.0 0.136 H -66.4 -38.0 19.0 0.136 0.0 HOH
 4.137
 CG2
 O
1s63 2 P49356 100.0 0.0 X-RAY
 2004-07-27 THR B:124 B:124 24.0 0.171 H -65.1 -43.2 24.0 0.171 0.0 HOH
 4.258
 OG1
 O
1sa4 2 P49356 100.0 0.0 X-RAY
 2004-06-08 THR B:124 B:124 27.0 0.193 H -65.4 -42.3 27.0 0.193 0.0 HOH
 3.595
 OG1
 O
1tn6 2 P49356 100.0 0.0 X-RAY
 2004-11-02 THR B:124 B:624 20.0 0.143 H -64.7 -38.2 20.0 0.143 0.0 HOH
 4.073
 OG1
 O
2f0y 2 P49356 100.0 0.0 X-RAY
 2006-11-14 THR B:124 B:124 20.0 0.143 H -60.4 -46.8 20.0 0.143 0.0 HOH
 4.531
 OG1
 O
2h6f 2 P49356 100.0 0.0 X-RAY
 2006-08-29 THR B:124 B:624 39.0 0.279 H -64.7 -39.1 39.0 0.279 0.0 HOH
 4.104
 OG1
 O
2iej 2 P49356 100.0 0.0 X-RAY
 2007-01-23 THR B:124 B:624 37.0 0.264 H -62.3 -42.1 37.0 0.264 0.0 HOH
 3.114
 OG1
 O
3e37 2 P49356 100.0 0.0 X-RAY
 2009-03-10 THR B:124 B:126 20.0 0.143 H -62.5 -41.0 20.0 0.143 0.0 HOH
 4.075
 OG1
 O
2h6h 2 P49356 99.77 0.0 X-RAY
 2006-08-29 THR B:124 B:624 40.0 0.286 H -63.8 -38.7 40.0 0.286 0.0 HOH
 5.392
 O
 O
2h6g 2 P49356 99.77 0.0 X-RAY
 2006-08-29 THR B:124 B:624 41.0 0.293 H -65.4 -38.8 41.0 0.293 0.0 HOH
 4.409
 N
 O
2h6i 2 P49356 99.54 0.0 X-RAY
 2006-08-29 THR B:124 B:624 43.0 0.307 H -67.9 -32.0 43.0 0.307 0.0 HOH
 8.253
 N
 O
1o1r 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 THR B:124 B:124 26.0 0.186 H -61.7 -33.3 26.0 0.186 0.0 HOH
 3.881
 N
 O
1o1s 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 THR B:124 B:124 27.0 0.193 H -64.3 -33.5 27.0 0.193 0.0 HOH
 4.052
 N
 O
1o1t 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 THR B:124 B:124 25.0 0.179 H -64.8 -35.2 25.0 0.179 0.0 HOH
 4.125
 N
 O
3eu5 2 Q02293 98.12 0.0 X-RAY
 2009-07-07 THR B:124 B:124 36.0 0.257 H -69.5 -43.2 36.0 0.257 0.0 HOH
 6.294
 OG1
 O
4gtm 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 THR B:124 B:124 35.0 0.25 H -71.7 -33.6 35.0 0.25 0.0 HOH
 3.976
 CG2
 O
4gto 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 THR B:124 B:124 36.0 0.257 H -75.1 -32.3 36.0 0.257 0.0 HOH
 3.674
 OG1
 O
4gtp 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 THR B:124 B:124 38.0 0.271 H -78.3 -30.1 38.0 0.271 0.0 HOH
 2.571
 OG1
 O
4gtq 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 THR B:124 B:124 30.0 0.214 H -64.4 -41.3 30.0 0.214 0.0 HOH
 5.446
 O
 O
4gtr 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 THR B:124 B:124 37.0 0.264 H -68.5 -37.5 37.0 0.264 0.0 HOH
 4.445
 N
 O
3pz4 2 Q02293 98.11 0.0 X-RAY
 2011-05-11 THR B:123 B:124 41.0 0.293 H -69.7 -25.8 41.0 0.293 0.0 HOH
 5.356
 OG1
 O
1d8d 2 Q02293 96.57 0.0 X-RAY
 2000-02-09 THR B:124 B:124 37.0 0.264 H -62.9 -38.9 37.0 0.264 0.0 HOH
 5.816
 O
 O
1d8e 2 Q02293 96.57 0.0 X-RAY
 2000-03-20 THR B:124 B:124 37.0 0.264 H -52.6 -39.2 37.0 0.264 0.0 HOH
 9.328
 O
 O
1fpp 1 Q02293 96.57 0.0 X-RAY
 1999-06-08 THR A:124 B:124 33.0 0.236 H -59.4 -35.2 33.0 0.236 0.0
1ft1 2 Q02293 96.57 0.0 X-RAY
 1998-03-18 THR B:124 B:124 38.0 0.271 H -62.6 -35.0 38.0 0.271 0.0 HOH
 3.342
 OG1
 O
1jcr 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 THR B:124 B:124 36.0 0.257 H -64.3 -38.2 36.0 0.257 0.0 HOH
 4.221
 N
 O
1jcs 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 THR B:124 B:124 37.0 0.264 H -63.8 -39.8 37.0 0.264 0.0 HOH
 4.092
 N
 O
1kzo 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 THR B:124 B:124 37.0 0.264 H -62.1 -39.0 37.0 0.264 0.0 HOH
 5.839
 O
 O
1kzp 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 THR B:124 B:124 37.0 0.264 H -64.9 -36.6 37.0 0.264 0.0 HOH
 5.800
 O
 O
1o5m 2 Q02293 96.57 0.0 X-RAY
 2003-10-21 THR B:124 B:124 26.0 0.186 H -65.7 -32.1 26.0 0.186 0.0 HOH
 4.156
 N
 O
1qbq 2 Q02293 96.57 0.0 X-RAY
 1999-06-18 THR B:124 B:124 43.0 0.307 H -68.0 -47.9 43.0 0.307 0.0 HOH
 3.919
 OG1
 O
1sa5 2 Q02293 96.57 0.0 X-RAY
 2004-06-08 THR B:124 B:124 37.0 0.264 H -71.3 -37.6 37.0 0.264 0.0 HOH
 5.525
 O
 O
1tn7 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 THR B:124 B:624 36.0 0.257 H -62.9 -37.2 36.0 0.257 0.0 HOH
 3.889
 N
 O
1tn8 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 THR B:124 B:624 38.0 0.271 H -70.8 -33.9 38.0 0.271 0.0 HOH
 5.731
 O
 O
3dpy 2 Q02293 96.57 0.0 X-RAY
 2008-09-30 THR B:124 B:124 37.0 0.264 H -74.8 -28.7 37.0 0.264 0.0
3e30 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 THR B:124 B:124 29.0 0.207 H -61.3 -42.6 29.0 0.207 0.0 HOH
 5.290
 CG2
 O
3e32 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 THR B:124 B:124 32.0 0.229 H -64.6 -37.7 32.0 0.229 0.0 HOH
 5.588
 O
 O
3e33 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 THR B:124 B:124 35.0 0.25 H -63.1 -39.1 35.0 0.25 0.0 HOH
 5.442
 O
 O
3e34 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 THR B:124 B:124 33.0 0.236 H -65.1 -39.5 33.0 0.236 0.0 HOH
 3.961
 N
 O
3ksl 2 Q02293 96.57 0.0 X-RAY
 2009-12-22 THR B:124 B:124 28.0 0.2 H -62.7 -42.1 28.0 0.2 0.0 HOH
 5.644
 O
 O
3ksq 2 Q02293 96.57 0.0 X-RAY
 2010-01-26 THR B:124 B:124 37.0 0.264 H -61.5 -44.8 37.0 0.264 0.0 HOH
 3.928
 N
 O
7rn5 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 THR B:124 B:124 34.0 0.243 H -64.7 -41.9 34.0 0.243 0.0 HOH
 3.206
 HA
 O
7rni 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 THR B:124 B:124 36.0 0.257 H -61.8 -44.1 36.0 0.257 0.0 HOH
 3.217
 HA
 O
2zir 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 THR B:127 B:124 24.0 0.171 H -61.6 -35.7 24.0 0.171 0.0 HOH
 3.988
 N
 O
2zis 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 THR B:127 B:124 24.0 0.171 H -68.1 -36.7 24.0 0.171 0.0 HOH
 5.451
 O
 O
3euv 2 Q02293 97.65 0.0 X-RAY
 2009-07-07 THR B:124 B:124 22.0 0.157 H -66.1 -36.4 22.0 0.157 0.0 HOH
 7.191
 O
 O
1n95 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 THR B:103 B:124 44.0 0.314 H -66.9 -47.7 44.0 0.314 0.0
1n9a 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 THR B:103 B:124 44.0 0.314 H -67.0 -47.8 44.0 0.314 0.0
1ni1 2 Q02293 98.26 0.0 X-RAY
 2004-04-06 THR B:103 B:124 54.0 0.386 H -53.6 -35.8 54.0 0.386 0.0
1nl4 2 Q02293 98.25 0.0 X-RAY
 2003-02-11 THR B:102 B:124 42.0 0.3 H -58.8 -50.4 42.0 0.3 0.0
2bed 2 Q02293 98.25 0.0 X-RAY
 2006-08-08 THR B:102 B:124 37.0 0.264 H -55.4 -33.8 37.0 0.264 0.0 HOH
 3.302
 CG2
 O
2r2l 2 Q02293 98.25 0.0 X-RAY
 2008-03-11 THR B:102 B:124 24.0 0.171 H -60.7 -37.4 24.0 0.171 0.0 HOH
 3.941
 N
 O
1ft2 2 Q02293 98.25 0.0 X-RAY
 1998-11-04 THR B:103 B:124 39.0 0.279 H -66.3 -39.5 39.0 0.279 0.0
1n94 2 Q02293 98.24 0.0 X-RAY
 2003-01-07 THR B:103 B:124 39.0 0.279 H -64.3 -66.4 39.0 0.279 0.0
1x81 2 Q02293 98.24 0.0 X-RAY
 2004-12-21 THR B:103 B:124 43.0 0.307 H -56.9 -43.6 43.0 0.307 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p49356-f1 1 P49356 100.0 0.0 THR A:124 A:124 40.0 0.286 H -60.3 -40.5