wupsivus

Variant

Genome	Chromosome	Position	VCF ID	Ref	Alt	mRNA Change	mRNA Info
GRCh37	chr14	65494257	.	A	C	CCDS9769.1:NM_002028.3:c.461tAt>tCt_NP_002019.1:p.154Y>S	Homo sapiens farnesyltransferase, CAAX box, beta (FNTB), mRNA.

pdb_id	:
label_asym_id	:
label_seq_id	:
label_comp_id	:
auth_asym_id	:
auth_seq_id	:

alphafold_id	:
label_asym_id	:
label_seq_id	:
label_comp_id	:
auth_asym_id	:
auth_seq_id	:

PDB

Entity							Residue			Monomer					BioUnit				Ligand				View
PDB	Entity	Uniprot	Identity	Evalue	ExpMethod	Date	Name	Label	Auth	ASA	rASA	SS	φ	ψ	ASA	rASA	ΔASA	Interaction	Name	Distance	Atom(p)	Atom(l)	View
1jcq	2	P49356	100.0	0.0	X-RAY	2001-11-02	TYR	B:154	B:154	2.0	0.009	H	-61.7	-48.2	2.0	0.009	0.0		FPP 739 HOH	4.444 7.543 2.929	CE2 N OH	C15 OEM O
1ld7	2	P49356	100.0	0.0	X-RAY	2002-06-19	TYR	B:154	B:654	2.0	0.009	H	-59.2	-46.1	2.0	0.009	0.0		FPP U66 HOH	4.409 7.291 2.771	CE2 CE2 OH	C15 C5 O
1ld8	2	P49356	100.0	0.0	X-RAY	2002-06-19	TYR	B:154	B:654	2.0	0.009	H	-58.9	-46.9	2.0	0.009	0.0		ACY FPP U49 HOH	9.849 4.314 7.304 2.833	CD2 CE2 CD2 OH	CH3 C15 C7 O
1mzc	2	P49356	100.0	0.0	X-RAY	2003-07-08	TYR	B:154	B:654	3.0	0.013	H	-60.8	-47.6	3.0	0.013	0.0		FPP BNE HOH	4.621 6.587 2.887	CE2 CE2 OH	C15 C13 O
1s63	2	P49356	100.0	0.0	X-RAY	2004-07-27	TYR	B:154	B:154	2.0	0.009	H	-57.0	-47.7	2.0	0.009	0.0		FPP 778 HOH	4.550 6.689 2.851	CE2 CE2 OH	C15 CL31 O
1sa4	2	P49356	100.0	0.0	X-RAY	2004-06-08	TYR	B:154	B:154	3.0	0.013	H	-58.7	-47.3	3.0	0.013	0.0		FPP JAN HOH	4.612 7.815 2.765	CE2 CE2 OH	C15 CL2 O
1tn6	2	P49356	100.0	0.0	X-RAY	2004-11-02	TYR	B:154	B:654	2.0	0.009	H	-60.0	-46.2	2.0	0.009	0.0		FII HOH	4.429 2.851	CE2 OH	C6 O
2f0y	2	P49356	100.0	0.0	X-RAY	2006-11-14	TYR	B:154	B:154	3.0	0.013	H	-64.4	-43.8	3.0	0.013	0.0		FPP 3MN HOH	4.895 6.790 2.798	CE2 CD2 OH	C15 C27 O
2h6f	2	P49356	100.0	0.0	X-RAY	2006-08-29	TYR	B:154	B:654	3.0	0.013	H	-57.9	-46.4	3.0	0.013	0.0		FAR HOH	4.094 2.786	CE2 OH	C15 O
2iej	2	P49356	100.0	0.0	X-RAY	2007-01-23	TYR	B:154	B:654	3.0	0.013	H	-54.5	-50.2	3.0	0.013	0.0		S48 FII HOH	6.006 4.451 2.910	CE2 CD2 OH	CAA C6 O
3e37	2	P49356	100.0	0.0	X-RAY	2009-03-10	TYR	B:154	B:156	5.0	0.022	H	-54.4	-50.1	5.0	0.022	0.0		ED5 HOH	3.602 2.835	CD2 OH	CAC O
2h6h	2	P49356	99.77	0.0	X-RAY	2006-08-29	TYR	B:154	B:654	3.0	0.013	H	-58.8	-46.7	3.0	0.013	0.0		FAR HOH	4.172 2.814	CE2 OH	C15 O
2h6g	2	P49356	99.77	0.0	X-RAY	2006-08-29	TYR	B:154	B:654	17.0	0.074	H	-58.8	-46.6	17.0	0.074	0.0		GER HOH	3.287 2.918	CD2 OH	C19 O
2h6i	2	P49356	99.54	0.0	X-RAY	2006-08-29	TYR	B:154	B:654	24.0	0.104	H	-57.6	-49.9	24.0	0.104	0.0		GER HOH	3.451 3.328	CD2 O	C17 O
1o1r	2	Q02293	98.12	0.0	X-RAY	2003-05-06	TYR	B:154	B:154	2.0	0.009	H	-63.4	-45.1	2.0	0.009	0.0		GRG HOH	3.865 2.986	CE2 OH	C19 O
1o1s	2	Q02293	98.12	0.0	X-RAY	2003-05-06	TYR	B:154	B:154	2.0	0.009	H	-62.1	-46.6	2.0	0.009	0.0		1NH HOH	4.922 3.000	CD2 OH	C12 O
1o1t	2	Q02293	98.12	0.0	X-RAY	2003-05-06	TYR	B:154	B:154	2.0	0.009	H	-61.4	-44.7	2.0	0.009	0.0		2NH HOH	4.096 2.860	CE2 OH	C14 O
3eu5	2	Q02293	98.12	0.0	X-RAY	2009-07-07	TYR	B:154	B:154	3.0	0.013	H	-58.1	-41.6	3.0	0.013	0.0		GBO HOH	6.023 8.371	CE2 CD2	O6 O
4gtm	2	Q02293	98.12	0.0	X-RAY	2012-10-24	TYR	B:154	B:154	4.0	0.017	H	-55.1	-49.8	4.0	0.017	0.0		FPP 7TM HOH	4.370 6.730 2.903	CE2 CD2 OH	C14 OAE O
4gto	2	Q02293	98.12	0.0	X-RAY	2012-10-24	TYR	B:154	B:154	5.0	0.022	H	-58.4	-45.3	5.0	0.022	0.0		7TO HOH	3.552 2.904	CD2 OH	FAH O
4gtp	2	Q02293	98.12	0.0	X-RAY	2012-10-24	TYR	B:154	B:154	3.0	0.013	H	-71.3	-38.3	3.0	0.013	0.0		FPP 7TP DMS HOH	4.278 7.863 9.091 2.948	CE2 CD2 CD2 OH	C14 CAI S O
4gtq	2	Q02293	98.12	0.0	X-RAY	2012-10-24	TYR	B:154	B:154	4.0	0.017	H	-62.0	-42.3	4.0	0.017	0.0		FPP 7TQ HOH	4.667 7.545 2.686	CE2 CD2 OH	C15 OBH O
4gtr	2	Q02293	98.12	0.0	X-RAY	2012-10-24	TYR	B:154	B:154	17.0	0.074	H	-55.8	-44.5	17.0	0.074	0.0		7TR FPP HOH	3.829 5.544 2.868	CE2 CE2 OH	CAW C14 O
3pz4	2	Q02293	98.11	0.0	X-RAY	2011-05-11	TYR	B:153	B:154	3.0	0.013	H	-46.3	-51.2	3.0	0.013	0.0		FPP 3PZ HOH	4.239 6.987 2.942	CE2 CE2 OH	C15 C16 O
1d8d	2	Q02293	96.57	0.0	X-RAY	2000-02-09	TYR	B:154	B:154	2.0	0.009	H	-62.4	-49.2	2.0	0.009	0.0		FII HOH	4.580 2.867	CE2 OH	C6 O
1d8e	2	Q02293	96.57	0.0	X-RAY	2000-03-20	TYR	B:154	B:154	3.0	0.013	H	-61.4	-50.2	3.0	0.013	0.0		FII HOH	4.484 2.767	CE2 O	C6 O
1fpp	1	Q02293	96.57	0.0	X-RAY	1999-06-08	TYR	A:154	B:154	4.0	0.017	H	-68.7	-42.9	4.0	0.017	0.0		FPP HOH	4.349 3.070	CE1 OH	C15 O
1ft1	2	Q02293	96.57	0.0	X-RAY	1998-03-18	TYR	B:154	B:154	4.0	0.017	H	-60.0	-50.2	4.0	0.017	0.0		HOH	2.963	OH	O
1jcr	2	Q02293	96.57	0.0	X-RAY	2001-11-02	TYR	B:154	B:154	2.0	0.009	H	-62.2	-46.5	2.0	0.009	0.0		FPP HOH	4.551 2.932	CE2 OH	C15 O
1jcs	2	Q02293	96.57	0.0	X-RAY	2001-11-02	TYR	B:154	B:154	2.0	0.009	H	-64.2	-45.3	2.0	0.009	0.0		FII HOH	4.401 2.903	CE2 OH	C6 O
1kzo	2	Q02293	96.57	0.0	X-RAY	2002-10-16	TYR	B:154	B:154	1.0	0.004	H	-62.4	-47.1	1.0	0.004	0.0		FPP HOH	4.609 2.855	CE2 OH	C15 O
1kzp	2	Q02293	96.57	0.0	X-RAY	2002-10-16	TYR	B:154	B:154	2.0	0.009	H	-64.1	-45.9	2.0	0.009	0.0		FAR HOH	4.453 2.829	CE2 OH	C15 O
1o5m	2	Q02293	96.57	0.0	X-RAY	2003-10-21	TYR	B:154	B:154	2.0	0.009	H	-64.1	-44.3	2.0	0.009	0.0		FPP 336 HOH	4.321 6.127 2.980	CE2 CE2 OH	C14 CL16 O
1qbq	2	Q02293	96.57	0.0	X-RAY	1999-06-18	TYR	B:154	B:154	2.0	0.009	H	-57.8	-45.5	2.0	0.009	0.0		HFP HOH	4.480 2.714	CE2 OH	C15 O
1sa5	2	Q02293	96.57	0.0	X-RAY	2004-06-08	TYR	B:154	B:154	2.0	0.009	H	-70.2	-32.6	2.0	0.009	0.0		FPP BMV HOH	4.389 6.743 2.898	CE2 CE2 OH	C15 CAE O
1tn7	2	Q02293	96.57	0.0	X-RAY	2004-11-02	TYR	B:154	B:654	3.0	0.013	H	-62.9	-45.1	3.0	0.013	0.0		FII HOH	4.505 2.967	CE2 OH	C6 O
1tn8	2	Q02293	96.57	0.0	X-RAY	2004-11-02	TYR	B:154	B:654	3.0	0.013	H	-62.7	-45.8	3.0	0.013	0.0		FII HOH	4.461 2.972	CE2 OH	C6 O
3dpy	2	Q02293	96.57	0.0	X-RAY	2008-09-30	TYR	B:154	B:154	3.0	0.013	H	-63.1	-36.6	3.0	0.013	0.0		FPP HOH	4.420 9.631	CE2 N	C15 O
3e30	2	Q02293	96.57	0.0	X-RAY	2009-03-10	TYR	B:154	B:154	4.0	0.017	H	-59.8	-42.7	4.0	0.017	0.0		FPP ED4 HOH	4.742 7.886 2.973	CE2 CD2 OH	C14 CAU O
3e32	2	Q02293	96.57	0.0	X-RAY	2009-03-10	TYR	B:154	B:154	4.0	0.017	H	-59.0	-45.0	4.0	0.017	0.0		FPP ED2 HOH	4.707 8.043 9.326	CE2 CD2 N	C14 CAH O
3e33	2	Q02293	96.57	0.0	X-RAY	2009-03-10	TYR	B:154	B:154	2.0	0.009	H	-55.3	-49.2	2.0	0.009	0.0		FPP ED7 HOH	4.421 7.894 2.866	CE2 CD2 OH	C15 CAL O
3e34	2	Q02293	96.57	0.0	X-RAY	2009-03-10	TYR	B:154	B:154	3.0	0.013	H	-55.8	-47.5	3.0	0.013	0.0		FPP ED1 HOH	4.610 6.830 2.955	CE2 CE2 OH	C15 CAL O
3ksl	2	Q02293	96.57	0.0	X-RAY	2009-12-22	TYR	B:154	B:154	3.0	0.013	H	-61.1	-47.5	3.0	0.013	0.0		SZH HOH	3.612 2.807	CE2 OH	F26 O
3ksq	2	Q02293	96.57	0.0	X-RAY	2010-01-26	TYR	B:154	B:154	2.0	0.009	H	-61.8	-47.4	2.0	0.009	0.0		FPP Z96 HOH	4.321 8.021 2.789	CE2 CE2 OH	C14 C5 O
7rn5	2	Q02293	96.57	0.0	X-RAY	2021-09-08	TYR	B:154	B:154	4.0	0.017	H	-57.7	-47.8	4.0	0.017	0.0		60I HOH	3.306 2.823	CD2 OH	H21 O
7rni	2	Q02293	96.57	0.0	X-RAY	2021-09-08	TYR	B:154	B:154	4.0	0.017	H	-58.9	-48.4	4.0	0.017	0.0		ACE 60I HOH	9.114 3.363 2.731	HE1 CD2 OH	H1 H21 O
2zir	2	Q02293	96.57	0.0	X-RAY	2009-02-24	TYR	B:157	B:154	2.0	0.009	H	-65.8	-41.5	2.0	0.009	0.0		FPP NH7 HOH	4.462 8.486 2.878	CE2 CD2 OH	C14 C34 O
2zis	2	Q02293	96.57	0.0	X-RAY	2009-02-24	TYR	B:157	B:154	3.0	0.013	H	-68.0	-40.8	3.0	0.013	0.0		FPP NH8 HOH	4.368 7.218 2.754	CE2 CE2 OH	C14 N38 O
3euv	2	Q02293	97.65	0.0	X-RAY	2009-07-07	THR	B:154	B:154	11.0	0.079	H	-64.2	-37.3	11.0	0.079	0.0		GBO HOH	3.804 4.030	CB CG2	S1 O
1n95	2	Q02293	98.26	0.0	X-RAY	2003-01-07	TYR	B:133	B:154	2.0	0.009	H	-55.3	-45.1	2.0	0.009	0.0		HFP FTH	4.526 7.009	CE2 CE2	C15 C30
1n9a	2	Q02293	98.26	0.0	X-RAY	2003-01-07	TYR	B:133	B:154	2.0	0.009	H	-53.3	-45.8	2.0	0.009	0.0		HFP FTI	4.534 8.307	CE2 CE2	C15 C11
1ni1	2	Q02293	98.26	0.0	X-RAY	2004-04-06	TYR	B:133	B:154	2.0	0.009	H	-59.6	-48.3	2.0	0.009	0.0		HFP 2C5	4.204 7.205	CE2 CE2	C15 CL1
1nl4	2	Q02293	98.25	0.0	X-RAY	2003-02-11	TYR	B:132	B:154	3.0	0.013	H	-58.7	-44.8	3.0	0.013	0.0		HFP FTL	4.033 7.034	CE2 CE2	C15 C54
2bed	2	Q02293	98.25	0.0	X-RAY	2006-08-08	TYR	B:132	B:154	2.0	0.009	H	-54.1	-56.3	2.0	0.009	0.0		FPP 736 HOH	4.529 7.166 3.596	CE2 CD2 O	C14 C6 O
2r2l	2	Q02293	98.25	0.0	X-RAY	2008-03-11	TYR	B:132	B:154	2.0	0.009	H	-61.1	-43.0	2.0	0.009	0.0		FPP PB9 HOH	4.539 7.971 2.853	CE2 CD2 OH	C14 C40 O
1ft2	2	Q02293	98.25	0.0	X-RAY	1998-11-04	TYR	B:133	B:154	10.0	0.043	H	-53.7	-48.3	10.0	0.043	0.0		FPP	5.163	CE2	C15
1n94	2	Q02293	98.24	0.0	X-RAY	2003-01-07	TYR	B:133	B:154	5.0	0.022	H	-67.0	-64.1	5.0	0.022	0.0		HFP TIN	5.503 8.303	CE2 CD2	C15 C55
1x81	2	Q02293	98.24	0.0	X-RAY	2004-12-21	TYR	B:133	B:154	5.0	0.022	H	-75.0	-29.9	5.0	0.022	0.0		JAN	8.281	CE2	CL2

AlphaFold DB

Entity					Residue			Monomer					View
ID	Entity	Uniprot	Identity	Evalue	Name	Label	Auth	ASA	rASA	SS	φ	ψ	View
af-p49356-f1	1	P49356	100.0	0.0	TYR	A:154	A:154	1.0	0.004	H	-56.2	-50.0

wupsivus
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