Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 65494432 . T A CCDS9769.1:NM_002028.3:c.538Tat>Aat_NP_002019.1:p.180Y>N Homo sapiens farnesyltransferase, CAAX box, beta (FNTB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1jcq 2 P49356 100.0 0.0 X-RAY
 2001-11-02 TYR B:180 B:180 3.0 0.013 H -60.2 -49.3 3.0 0.013 0.0 739
HOH
 9.859
3.430
 OH
OH
 CEM
O
1ld7 2 P49356 100.0 0.0 X-RAY
 2002-06-19 TYR B:180 B:680 2.0 0.009 H -61.6 -46.3 2.0 0.009 0.0 HOH
 3.083
 OH
 O
1ld8 2 P49356 100.0 0.0 X-RAY
 2002-06-19 TYR B:180 B:680 2.0 0.009 H -61.5 -47.1 2.0 0.009 0.0 HOH
 3.104
 OH
 O
1mzc 2 P49356 100.0 0.0 X-RAY
 2003-07-08 TYR B:180 B:680 3.0 0.013 H -60.6 -47.4 3.0 0.013 0.0 HOH
 3.415
 OH
 O
1s63 2 P49356 100.0 0.0 X-RAY
 2004-07-27 TYR B:180 B:180 2.0 0.009 H -60.1 -46.6 2.0 0.009 0.0 HOH
 3.154
 OH
 O
1sa4 2 P49356 100.0 0.0 X-RAY
 2004-06-08 TYR B:180 B:180 2.0 0.009 H -61.2 -46.8 2.0 0.009 0.0 HOH
 3.257
 OH
 O
1tn6 2 P49356 100.0 0.0 X-RAY
 2004-11-02 TYR B:180 B:680 2.0 0.009 H -61.4 -45.2 2.0 0.009 0.0 HOH
 3.298
 OH
 O
2f0y 2 P49356 100.0 0.0 X-RAY
 2006-11-14 TYR B:180 B:180 3.0 0.013 H -75.2 -43.9 3.0 0.013 0.0 HOH
 2.827
 OH
 O
2h6f 2 P49356 100.0 0.0 X-RAY
 2006-08-29 TYR B:180 B:680 2.0 0.009 H -61.7 -44.6 2.0 0.009 0.0 HOH
 3.140
 OH
 O
2iej 2 P49356 100.0 0.0 X-RAY
 2007-01-23 TYR B:180 B:680 2.0 0.009 H -61.2 -46.8 2.0 0.009 0.0 HOH
 3.048
 OH
 O
3e37 2 P49356 100.0 0.0 X-RAY
 2009-03-10 TYR B:180 B:182 1.0 0.004 H -58.9 -46.6 1.0 0.004 0.0 HOH
 3.014
 OH
 O
2h6h 2 P49356 99.77 0.0 X-RAY
 2006-08-29 TYR B:180 B:680 2.0 0.009 H -61.8 -45.4 2.0 0.009 0.0 HOH
 3.177
 OH
 O
2h6g 2 P49356 99.77 0.0 X-RAY
 2006-08-29 TYR B:180 B:680 2.0 0.009 H -60.3 -45.3 2.0 0.009 0.0 HOH
 3.369
 OH
 O
2h6i 2 P49356 99.54 0.0 X-RAY
 2006-08-29 TYR B:180 B:680 1.0 0.004 H -64.6 -43.4 1.0 0.004 0.0
1o1r 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 TYR B:180 B:180 8.0 0.035 H -54.7 -52.4 8.0 0.035 0.0 HOH
 2.851
 OH
 O
1o1s 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 TYR B:180 B:180 8.0 0.035 H -61.9 -48.0 8.0 0.035 0.0 HOH
 2.589
 OH
 O
1o1t 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 TYR B:180 B:180 7.0 0.03 H -53.0 -51.5 7.0 0.03 0.0 MG
2NH
HOH
 9.612
9.632
2.878
 OH
OH
OH
 MG
CE
O
3eu5 2 Q02293 98.12 0.0 X-RAY
 2009-07-07 TYR B:180 B:180 5.0 0.022 H -52.4 -49.0 5.0 0.022 0.0 HOH
 6.113
 CB
 O
4gtm 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 TYR B:180 B:180 11.0 0.048 H -53.4 -48.7 11.0 0.048 0.0 HOH
 2.918
 OH
 O
4gto 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 TYR B:180 B:180 9.0 0.039 H -57.3 -47.4 9.0 0.039 0.0 HOH
 2.789
 OH
 O
4gtp 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 TYR B:180 B:180 6.0 0.026 H -46.1 -52.6 6.0 0.026 0.0 HOH
 2.714
 OH
 O
4gtq 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 TYR B:180 B:180 9.0 0.039 H -54.0 -51.6 9.0 0.039 0.0 7TQ
HOH
 9.377
2.475
 OH
OH
 CAI
O
4gtr 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 TYR B:180 B:180 9.0 0.039 H -48.6 -48.7 9.0 0.039 0.0 HOH
 2.743
 OH
 O
3pz4 2 Q02293 98.11 0.0 X-RAY
 2011-05-11 TYR B:179 B:180 8.0 0.035 H -43.1 -49.2 8.0 0.035 0.0 HOH
 2.844
 OH
 O
1d8d 2 Q02293 96.57 0.0 X-RAY
 2000-02-09 TYR B:180 B:180 8.0 0.035 H -55.4 -50.1 8.0 0.035 0.0 HOH
 3.164
 OH
 O
1d8e 2 Q02293 96.57 0.0 X-RAY
 2000-03-20 TYR B:180 B:180 7.0 0.03 H -49.6 -58.1 7.0 0.03 0.0 HOH
 3.323
 OH
 O
1fpp 1 Q02293 96.57 0.0 X-RAY
 1999-06-08 TYR A:180 B:180 9.0 0.039 H -53.6 -50.9 9.0 0.039 0.0
1ft1 2 Q02293 96.57 0.0 X-RAY
 1998-03-18 TYR B:180 B:180 8.0 0.035 H -63.3 -42.2 8.0 0.035 0.0 HOH
 3.385
 OH
 O
1jcr 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 TYR B:180 B:180 8.0 0.035 H -57.2 -51.2 8.0 0.035 0.0 HOH
 3.075
 OH
 O
1jcs 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 TYR B:180 B:180 8.0 0.035 H -57.5 -52.5 8.0 0.035 0.0 HOH
 2.977
 OH
 O
1kzo 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 TYR B:180 B:180 10.0 0.043 H -55.5 -51.8 10.0 0.043 0.0 HOH
 2.971
 OH
 O
1kzp 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 TYR B:180 B:180 8.0 0.035 H -56.1 -50.1 8.0 0.035 0.0 HOH
 3.080
 OH
 O
1o5m 2 Q02293 96.57 0.0 X-RAY
 2003-10-21 TYR B:180 B:180 6.0 0.026 H -62.2 -47.7 6.0 0.026 0.0 HOH
 3.049
 OH
 O
1qbq 2 Q02293 96.57 0.0 X-RAY
 1999-06-18 TYR B:180 B:180 5.0 0.022 H -56.6 -51.3 5.0 0.022 0.0 HOH
 3.413
 CA
 O
1sa5 2 Q02293 96.57 0.0 X-RAY
 2004-06-08 TYR B:180 B:180 8.0 0.035 H -55.6 -52.9 8.0 0.035 0.0 HOH
 2.836
 OH
 O
1tn7 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 TYR B:180 B:680 7.0 0.03 H -59.2 -50.2 7.0 0.03 0.0 HOH
 3.011
 OH
 O
1tn8 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 TYR B:180 B:680 8.0 0.035 H -61.2 -47.3 8.0 0.035 0.0 HOH
 3.190
 OH
 O
3dpy 2 Q02293 96.57 0.0 X-RAY
 2008-09-30 TYR B:180 B:180 6.0 0.026 H -59.4 -47.3 6.0 0.026 0.0 HOH
 6.028
 CB
 O
3e30 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 TYR B:180 B:180 10.0 0.043 H -50.0 -55.4 10.0 0.043 0.0 ED4
HOH
 9.764
2.951
 OH
OH
 CAD
O
3e32 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 TYR B:180 B:180 10.0 0.043 H -55.6 -51.9 10.0 0.043 0.0 HOH
 3.471
 CA
 O
3e33 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 TYR B:180 B:180 8.0 0.035 H -57.0 -50.6 8.0 0.035 0.0 HOH
 2.978
 OH
 O
3e34 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 TYR B:180 B:180 10.0 0.043 H -58.5 -47.9 10.0 0.043 0.0 HOH
 3.499
 CA
 O
3ksl 2 Q02293 96.57 0.0 X-RAY
 2009-12-22 TYR B:180 B:180 8.0 0.035 H -58.4 -47.9 8.0 0.035 0.0 MG
HOH
 9.657
2.975
 OH
OH
 MG
O
3ksq 2 Q02293 96.57 0.0 X-RAY
 2010-01-26 TYR B:180 B:180 6.0 0.026 H -58.6 -48.2 6.0 0.026 0.0 MG
HOH
 9.583
3.007
 OH
OH
 MG
O
7rn5 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 TYR B:180 B:180 8.0 0.035 H -63.8 -47.0 8.0 0.035 0.0 HOH
 1.916
 HH
 O
7rni 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 TYR B:180 B:180 9.0 0.039 H -62.9 -44.1 9.0 0.039 0.0 MG
HOH
 9.667
2.629
 HH
HE1
 MG
O
2zir 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 TYR B:183 B:180 5.0 0.022 H -59.6 -49.2 5.0 0.022 0.0 HOH
 3.209
 CA
 O
2zis 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 TYR B:183 B:180 6.0 0.026 H -63.5 -44.4 6.0 0.026 0.0 HOH
 3.187
 OH
 O
3euv 2 Q02293 97.65 0.0 X-RAY
 2009-07-07 TYR B:180 B:180 9.0 0.039 H -48.5 -48.4 9.0 0.039 0.0
1n95 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 TYR B:159 B:180 5.0 0.022 H -57.2 -52.0 5.0 0.022 0.0
1n9a 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 TYR B:159 B:180 4.0 0.017 H -57.8 -50.6 4.0 0.017 0.0
1ni1 2 Q02293 98.26 0.0 X-RAY
 2004-04-06 TYR B:159 B:180 6.0 0.026 H -65.3 -55.6 6.0 0.026 0.0
1nl4 2 Q02293 98.25 0.0 X-RAY
 2003-02-11 TYR B:158 B:180 6.0 0.026 H -49.3 -59.8 6.0 0.026 0.0
2bed 2 Q02293 98.25 0.0 X-RAY
 2006-08-08 TYR B:158 B:180 5.0 0.022 H -69.1 -51.4 5.0 0.022 0.0 HOH
 3.725
 CD1
 O
2r2l 2 Q02293 98.25 0.0 X-RAY
 2008-03-11 TYR B:158 B:180 8.0 0.035 H -62.5 -47.4 8.0 0.035 0.0 PB9
HOH
 9.157
2.718
 OH
OH
 C56
O
1ft2 2 Q02293 98.25 0.0 X-RAY
 1998-11-04 TYR B:159 B:180 7.0 0.03 H -59.1 -48.8 7.0 0.03 0.0
1n94 2 Q02293 98.24 0.0 X-RAY
 2003-01-07 TYR B:159 B:180 8.0 0.035 H -54.0 -57.6 8.0 0.035 0.0
1x81 2 Q02293 98.24 0.0 X-RAY
 2004-12-21 TYR B:159 B:180 7.0 0.03 H -50.9 -56.0 7.0 0.03 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p49356-f1 1 P49356 100.0 0.0 TYR A:180 A:180 4.0 0.017 H -63.9 -45.7