Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 65499341 . G A CCDS9769.1:NM_002028.3:c.619Gct>Act_NP_002019.1:p.207A>T Homo sapiens farnesyltransferase, CAAX box, beta (FNTB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1jcq 2 P49356 100.0 0.0 X-RAY
 2001-11-02 ALA B:207 B:207 0.0 0.0 H -65.0 -50.8 0.0 0.0 0.0 FPP
HOH
 8.322
7.475
 N
O
 C15
O
1ld7 2 P49356 100.0 0.0 X-RAY
 2002-06-19 ALA B:207 B:707 0.0 0.0 H -65.9 -48.8 0.0 0.0 0.0 FPP
HOH
 8.189
7.427
 N
O
 C15
O
1ld8 2 P49356 100.0 0.0 X-RAY
 2002-06-19 ALA B:207 B:707 0.0 0.0 H -64.3 -50.1 0.0 0.0 0.0 FPP
HOH
 8.082
7.434
 N
O
 C15
O
1mzc 2 P49356 100.0 0.0 X-RAY
 2003-07-08 ALA B:207 B:707 0.0 0.0 H -65.1 -49.2 0.0 0.0 0.0 FPP
HOH
 8.462
7.439
 N
O
 C15
O
1s63 2 P49356 100.0 0.0 X-RAY
 2004-07-27 ALA B:207 B:207 0.0 0.0 H -63.3 -50.5 0.0 0.0 0.0 FPP
HOH
 8.151
7.424
 N
O
 C15
O
1sa4 2 P49356 100.0 0.0 X-RAY
 2004-06-08 ALA B:207 B:207 0.0 0.0 H -64.4 -48.6 0.0 0.0 0.0 FPP
HOH
 8.575
7.342
 N
O
 C15
O
1tn6 2 P49356 100.0 0.0 X-RAY
 2004-11-02 ALA B:207 B:707 0.0 0.0 H -63.2 -49.3 0.0 0.0 0.0 FII
HOH
 8.460
7.455
 N
O
 C6
O
2f0y 2 P49356 100.0 0.0 X-RAY
 2006-11-14 ALA B:207 B:207 0.0 0.0 H -64.0 -40.5 0.0 0.0 0.0 FPP
HOH
 8.579
7.305
 N
N
 C15
O
2h6f 2 P49356 100.0 0.0 X-RAY
 2006-08-29 ALA B:207 B:707 0.0 0.0 H -65.0 -48.3 0.0 0.0 0.0 FAR
HOH
 8.192
7.436
 N
O
 C15
O
2iej 2 P49356 100.0 0.0 X-RAY
 2007-01-23 ALA B:207 B:707 0.0 0.0 H -63.7 -49.0 0.0 0.0 0.0 FII
HOH
 8.078
7.401
 N
O
 C6
O
3e37 2 P49356 100.0 0.0 X-RAY
 2009-03-10 ALA B:207 B:209 0.0 0.0 H -60.8 -49.5 0.0 0.0 0.0 ED5
HOH
 7.781
7.451
 N
O
 CAC
O
2h6h 2 P49356 99.77 0.0 X-RAY
 2006-08-29 ALA B:207 B:707 0.0 0.0 H -65.0 -48.1 0.0 0.0 0.0 FAR
HOH
 8.019
7.438
 N
O
 C15
O
2h6g 2 P49356 99.77 0.0 X-RAY
 2006-08-29 ALA B:207 B:707 0.0 0.0 H -64.2 -50.2 0.0 0.0 0.0 GER
HOH
 8.092
7.437
 N
O
 C15
O
2h6i 2 P49356 99.54 0.0 X-RAY
 2006-08-29 ALA B:207 B:707 0.0 0.0 H -52.1 -57.5 0.0 0.0 0.0 GER
HOH
 8.053
7.538
 N
O
 C15
O
1o1r 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 ALA B:207 B:207 0.0 0.0 H -71.7 -49.8 0.0 0.0 0.0 GRG
HOH
 7.926
7.289
 N
O
 C19
O
1o1s 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 ALA B:207 B:207 0.0 0.0 H -72.2 -50.3 0.0 0.0 0.0 1NH
HOH
 8.347
7.439
 N
O
 C12
O
1o1t 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 ALA B:207 B:207 0.0 0.0 H -69.7 -47.4 0.0 0.0 0.0 2NH
HOH
 7.894
7.416
 N
O
 C14
O
3eu5 2 Q02293 98.12 0.0 X-RAY
 2009-07-07 ALA B:207 B:207 0.0 0.0 H -58.7 -53.3 0.0 0.0 0.0 GBO
HOH
 9.904
7.726
 N
CB
 O6
O
4gtm 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 ALA B:207 B:207 0.0 0.0 H -63.4 -46.3 0.0 0.0 0.0 FPP
HOH
 8.249
7.444
 N
CB
 C14
O
4gto 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 ALA B:207 B:207 0.0 0.0 H -65.1 -46.0 0.0 0.0 0.0 7TO
HOH
 7.294
7.604
 N
O
 FAJ
O
4gtp 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 ALA B:207 B:207 0.0 0.0 H -54.4 -51.6 0.0 0.0 0.0 FPP
 8.066
 N
 C14
4gtq 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 ALA B:207 B:207 0.0 0.0 H -54.5 -48.4 0.0 0.0 0.0 FPP
HOH
 8.434
6.964
 N
O
 C14
O
4gtr 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 ALA B:207 B:207 0.0 0.0 H -64.2 -49.8 0.0 0.0 0.0 7TR
FPP
HOH
 9.490
7.976
7.511
 N
N
CB
 CAA
C14
O
3pz4 2 Q02293 98.11 0.0 X-RAY
 2011-05-11 ALA B:206 B:207 0.0 0.0 H -61.3 -55.6 0.0 0.0 0.0 FPP
HOH
 7.772
7.227
 N
N
 C15
O
1d8d 2 Q02293 96.57 0.0 X-RAY
 2000-02-09 ALA B:207 B:207 0.0 0.0 H -65.7 -47.7 0.0 0.0 0.0 FII
HOH
 8.519
7.433
 N
O
 C6
O
1d8e 2 Q02293 96.57 0.0 X-RAY
 2000-03-20 ALA B:207 B:207 0.0 0.0 H -57.3 -45.1 0.0 0.0 0.0 FII
HOH
 8.586
7.475
 N
N
 C6
O
1fpp 1 Q02293 96.57 0.0 X-RAY
 1999-06-08 ALA A:207 B:207 0.0 0.0 H -62.1 -42.7 0.0 0.0 0.0 FPP
 8.619
 N
 C14
1ft1 2 Q02293 96.57 0.0 X-RAY
 1998-03-18 ALA B:207 B:207 0.0 0.0 H -67.9 -48.6 0.0 0.0 0.0 HOH
 7.439
 O
 O
1jcr 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 ALA B:207 B:207 0.0 0.0 H -62.6 -47.5 0.0 0.0 0.0 FPP
HOH
 8.123
7.407
 N
O
 C15
O
1jcs 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 ALA B:207 B:207 0.0 0.0 H -65.0 -47.2 0.0 0.0 0.0 FII
HOH
 7.992
7.353
 N
O
 C6
O
1kzo 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 ALA B:207 B:207 0.0 0.0 H -64.0 -49.0 0.0 0.0 0.0 FPP
HOH
 8.276
7.284
 N
O
 C15
O
1kzp 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 ALA B:207 B:207 0.0 0.0 H -64.8 -50.5 0.0 0.0 0.0 FAR
HOH
 8.113
7.482
 N
O
 C15
O
1o5m 2 Q02293 96.57 0.0 X-RAY
 2003-10-21 ALA B:207 B:207 0.0 0.0 H -71.5 -48.7 0.0 0.0 0.0 FPP
HOH
 8.151
7.415
 N
O
 C14
O
1qbq 2 Q02293 96.57 0.0 X-RAY
 1999-06-18 ALA B:207 B:207 0.0 0.0 H -61.7 -51.0 0.0 0.0 0.0 HFP
HOH
 8.528
7.022
 N
CB
 C15
O
1sa5 2 Q02293 96.57 0.0 X-RAY
 2004-06-08 ALA B:207 B:207 0.0 0.0 H -66.2 -53.1 0.0 0.0 0.0 FPP
HOH
 8.688
7.322
 N
O
 C15
O
1tn7 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 ALA B:207 B:707 0.0 0.0 H -64.6 -51.5 0.0 0.0 0.0 FII
HOH
 8.504
7.401
 N
O
 C6
O
1tn8 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 ALA B:207 B:707 0.0 0.0 H -64.5 -50.1 0.0 0.0 0.0 FII
HOH
 8.589
7.436
 N
O
 C6
O
3dpy 2 Q02293 96.57 0.0 X-RAY
 2008-09-30 ALA B:207 B:207 0.0 0.0 H -59.9 -45.8 0.0 0.0 0.0 FPP
 8.760
 N
 C15
3e30 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 ALA B:207 B:207 0.0 0.0 H -64.6 -47.9 0.0 0.0 0.0 FPP
HOH
 8.297
7.387
 N
O
 C14
O
3e32 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 ALA B:207 B:207 0.0 0.0 H -63.4 -52.1 0.0 0.0 0.0 FPP
HOH
 8.251
7.691
 N
CB
 C14
O
3e33 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 ALA B:207 B:207 0.0 0.0 H -64.4 -47.2 0.0 0.0 0.0 FPP
HOH
 8.038
7.526
 N
O
 C15
O
3e34 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 ALA B:207 B:207 0.0 0.0 H -61.6 -47.4 0.0 0.0 0.0 FPP
HOH
 8.455
7.863
 N
CB
 C15
O
3ksl 2 Q02293 96.57 0.0 X-RAY
 2009-12-22 ALA B:207 B:207 0.0 0.0 H -63.2 -48.9 0.0 0.0 0.0 SZH
HOH
 8.177
7.434
 N
O
 F27
O
3ksq 2 Q02293 96.57 0.0 X-RAY
 2010-01-26 ALA B:207 B:207 0.0 0.0 H -68.5 -46.7 0.0 0.0 0.0 FPP
HOH
 8.283
7.415
 N
O
 C14
O
7rn5 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 ALA B:207 B:207 0.0 0.0 H -66.1 -49.4 0.0 0.0 0.0 60I
HOH
 6.992
6.901
 H
HB3
 H21
O
7rni 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 ALA B:207 B:207 0.0 0.0 H -64.5 -48.7 0.0 0.0 0.0 ACE
60I
HOH
 9.809
6.830
6.881
 O
H
HB3
 H1
H21
O
2zir 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 ALA B:210 B:207 0.0 0.0 H -66.7 -48.3 0.0 0.0 0.0 FPP
HOH
 8.774
7.469
 N
CB
 C14
O
2zis 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 ALA B:210 B:207 0.0 0.0 H -66.8 -47.7 0.0 0.0 0.0 FPP
HOH
 8.535
7.510
 N
O
 C14
O
3euv 2 Q02293 97.65 0.0 X-RAY
 2009-07-07 ALA B:207 B:207 0.0 0.0 H -51.5 -46.8 0.0 0.0 0.0 GBO
HOH
 8.117
7.398
 N
CB
 C14
O
1n95 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 ALA B:186 B:207 0.0 0.0 H -61.2 -52.1 0.0 0.0 0.0 HFP
 8.467
 N
 C15
1n9a 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 ALA B:186 B:207 0.0 0.0 H -61.6 -52.3 0.0 0.0 0.0 HFP
 8.482
 N
 C15
1ni1 2 Q02293 98.26 0.0 X-RAY
 2004-04-06 ALA B:186 B:207 0.0 0.0 H -62.7 -35.4 0.0 0.0 0.0 HFP
 8.239
 N
 C15
1nl4 2 Q02293 98.25 0.0 X-RAY
 2003-02-11 ALA B:185 B:207 0.0 0.0 H -52.0 -58.6 0.0 0.0 0.0 HFP
 7.695
 N
 C15
2bed 2 Q02293 98.25 0.0 X-RAY
 2006-08-08 ALA B:185 B:207 0.0 0.0 H -62.5 -59.5 0.0 0.0 0.0 FPP
HOH
 8.277
6.901
 N
O
 C14
O
2r2l 2 Q02293 98.25 0.0 X-RAY
 2008-03-11 ALA B:185 B:207 0.0 0.0 H -66.9 -51.6 0.0 0.0 0.0 FPP
HOH
 8.216
7.443
 N
O
 C14
O
1ft2 2 Q02293 98.25 0.0 X-RAY
 1998-11-04 ALA B:186 B:207 0.0 0.0 H -63.9 -59.5 0.0 0.0 0.0 FPP
 9.377
 N
 C15
1n94 2 Q02293 98.24 0.0 X-RAY
 2003-01-07 ALA B:186 B:207 0.0 0.0 H -45.5 -69.7 0.0 0.0 0.0 HFP
 9.700
 N
 C15
1x81 2 Q02293 98.24 0.0 X-RAY
 2004-12-21 ALA B:186 B:207 0.0 0.0 H -51.0 -42.6 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p49356-f1 1 P49356 100.0 0.0 ALA A:207 A:207 0.0 0.0 H -63.2 -49.9