Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 65507631 . C A CCDS9769.1:NM_002028.3:c.816agC>agA_NP_002019.1:p.272S>R Homo sapiens farnesyltransferase, CAAX box, beta (FNTB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1jcq 2 P49356 100.0 0.0 X-RAY
 2001-11-02 SER B:272 B:272 26.0 0.226 H -69.7 -22.3 10.0 0.087 0.139 A:P49354:0.139
 GLC
FRU
HOH
 6.985
2.921
2.672
 OG
OG
O
 O5
O6
O
1ld7 2 P49356 100.0 0.0 X-RAY
 2002-06-19 SER B:272 B:772 24.0 0.209 H -71.1 -27.0 8.0 0.07 0.139 A:P49354:0.139
 GLC
FRU
HOH
 7.022
2.896
2.756
 OG
OG
O
 O5
O6
O
1ld8 2 P49356 100.0 0.0 X-RAY
 2002-06-19 SER B:272 B:772 29.0 0.252 H -68.9 -30.1 10.0 0.087 0.165 A:P49354:0.165
 GLC
FRU
HOH
 7.079
2.821
2.786
 OG
OG
O
 O5
O6
O
1mzc 2 P49356 100.0 0.0 X-RAY
 2003-07-08 SER B:272 B:772 29.0 0.252 H -65.8 -31.5 10.0 0.087 0.165 A:P49354:0.165
 GLC
FRU
HOH
 7.053
2.856
2.770
 OG
OG
O
 O5
O6
O
1s63 2 P49356 100.0 0.0 X-RAY
 2004-07-27 SER B:272 B:272 25.0 0.217 H -72.7 -28.0 8.0 0.07 0.147 A:P49354:0.148
 GLC
FRU
HOH
 6.872
2.800
2.731
 OG
OG
O
 O5
O6
O
1sa4 2 P49356 100.0 0.0 X-RAY
 2004-06-08 SER B:272 B:272 25.0 0.217 H -71.3 -28.9 9.0 0.078 0.139 A:P49354:0.139
 GLC
FRU
HOH
 7.000
2.851
2.758
 OG
OG
O
 O5
O6
O
1tn6 2 P49356 100.0 0.0 X-RAY
 2004-11-02 SER B:272 B:772 24.0 0.209 H -70.2 -30.7 10.0 0.087 0.122 A:P49354:0.122
 GLC
FRU
HOH
 6.972
2.853
2.899
 OG
OG
O
 O5
O6
O
2f0y 2 P49356 100.0 0.0 X-RAY
 2006-11-14 SER B:272 B:272 32.0 0.278 H -71.4 -34.2 10.0 0.087 0.191 A:P49354:0.191
 HOH
 2.889
 OG
 O
2h6f 2 P49356 100.0 0.0 X-RAY
 2006-08-29 SER B:272 B:772 30.0 0.261 H -70.0 -30.2 12.0 0.104 0.157 A:P49354:0.157
 GLC
FRU
HOH
 6.988
2.862
2.903
 OG
OG
O
 O5
O6
O
2iej 2 P49356 100.0 0.0 X-RAY
 2007-01-23 SER B:272 B:772 24.0 0.209 H -70.9 -31.8 9.0 0.078 0.131 A:P49354:0.13
 GLC
FRU
HOH
 6.908
2.907
2.837
 OG
OG
O
 O5
O6
O
3e37 2 P49356 100.0 0.0 X-RAY
 2009-03-10 SER B:272 B:274 22.0 0.191 H -70.3 -32.0 7.0 0.061 0.13 A:P49354:0.13
 GLC
FRU
HOH
 6.899
2.901
2.885
 OG
OG
O
 O5
O6
O
2h6h 2 P49356 99.77 0.0 X-RAY
 2006-08-29 SER B:272 B:772 30.0 0.261 H -70.0 -30.6 13.0 0.113 0.148 A:P49354:0.148
 GLC
FRU
HOH
 6.982
2.838
2.885
 OG
OG
O
 O5
O6
O
2h6g 2 P49356 99.77 0.0 X-RAY
 2006-08-29 SER B:272 B:772 31.0 0.27 H -69.3 -30.3 12.0 0.104 0.166 A:P49354:0.165
 GLC
FRU
HOH
 7.029
2.881
2.794
 OG
OG
O
 O5
O6
O
2h6i 2 P49356 99.54 0.0 X-RAY
 2006-08-29 SER B:272 B:772 30.0 0.261 H -72.2 -31.7 12.0 0.104 0.157 A:P49354:0.157
 GLC
FRU
HOH
 6.940
2.696
8.364
 OG
OG
OG
 O6
O6
O
1o1r 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 SER B:272 B:272 32.0 0.278 H -67.1 -31.6 12.0 0.104 0.174 A:Q04631:0.174
 HOH
 2.912
 OG
 O
1o1s 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 SER B:272 B:272 32.0 0.278 H -66.3 -29.8 11.0 0.096 0.182 A:Q04631:0.183
 HOH
 2.831
 O
 O
1o1t 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 SER B:272 B:272 33.0 0.287 H -68.9 -28.3 13.0 0.113 0.174 A:Q04631:0.174
 HOH
 2.903
 OG
 O
3eu5 2 Q02293 98.12 0.0 X-RAY
 2009-07-07 SER B:272 B:272 27.0 0.235 H -69.5 -42.2 21.0 0.183 0.052 A:Q04631:0.052
 HOH
 2.927
 OG
 O
4gtm 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 SER B:272 B:272 29.0 0.252 H -63.7 -37.1 13.0 0.113 0.139 A:Q04631:0.139
 HOH
 2.902
 O
 O
4gto 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 SER B:272 B:272 30.0 0.261 H -69.1 -33.9 16.0 0.139 0.122 A:Q04631:0.122
 HOH
 2.726
 O
 O
4gtp 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 SER B:272 B:272 31.0 0.27 H -67.8 -35.9 11.0 0.096 0.174 A:Q04631:0.174
 HOH
 5.684
 N
 O
4gtq 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 SER B:272 B:272 32.0 0.278 H -71.8 -30.6 15.0 0.13 0.148 A:Q04631:0.148
 HOH
 2.552
 O
 O
4gtr 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 SER B:272 B:272 31.0 0.27 H -64.9 -35.3 15.0 0.13 0.14 A:Q04631:0.139
 HOH
 2.563
 O
 O
3pz4 2 Q02293 98.11 0.0 X-RAY
 2011-05-11 SER B:271 B:272 29.0 0.252 H -71.1 -36.7 19.0 0.165 0.087 A:Q04631:0.087
 HOH
 2.525
 CA
 O
1d8d 2 Q02293 96.57 0.0 X-RAY
 2000-02-09 SER B:272 B:272 30.0 0.261 H -70.3 -25.9 7.0 0.061 0.2 A:Q04631:0.2
 HOH
 2.725
 O
 O
1d8e 2 Q02293 96.57 0.0 X-RAY
 2000-03-20 SER B:272 B:272 28.0 0.243 H -57.6 -37.6 7.0 0.061 0.182 A:Q04631:0.183
 HOH
 6.410
 CB
 O
1fpp 1 Q02293 96.57 0.0 X-RAY
 1999-06-08 SER A:272 B:272 30.0 0.261 H -71.8 -25.1 6.0 0.052 0.209 B:Q04631:0.209
 HOH
 9.746
 O
 O
1ft1 2 Q02293 96.57 0.0 X-RAY
 1998-03-18 SER B:272 B:272 30.0 0.261 H -72.1 -19.3 10.0 0.087 0.174 A:Q04631:0.174
 HOH
 2.651
 O
 O
1jcr 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 SER B:272 B:272 30.0 0.261 H -69.0 -29.7 8.0 0.07 0.191 A:Q04631:0.191
 HOH
 2.552
 O
 O
1jcs 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 SER B:272 B:272 31.0 0.27 H -68.3 -30.7 10.0 0.087 0.183 A:Q04631:0.183
 HOH
 2.721
 O
 O
1kzo 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 SER B:272 B:272 32.0 0.278 H -71.6 -29.2 11.0 0.096 0.182 A:Q04631:0.183
 HOH
 2.693
 O
 O
1kzp 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 SER B:272 B:272 32.0 0.278 H -68.7 -30.2 10.0 0.087 0.191 A:Q04631:0.191
 HOH
 2.549
 O
 O
1o5m 2 Q02293 96.57 0.0 X-RAY
 2003-10-21 SER B:272 B:272 32.0 0.278 H -67.9 -32.1 12.0 0.104 0.174 A:Q04631:0.174
 HOH
 2.759
 O
 O
1qbq 2 Q02293 96.57 0.0 X-RAY
 1999-06-18 SER B:272 B:272 25.0 0.217 H -57.8 -31.6 11.0 0.096 0.121 A:Q04631:0.122
 HOH
 3.058
 OG
 O
1sa5 2 Q02293 96.57 0.0 X-RAY
 2004-06-08 SER B:272 B:272 31.0 0.27 H -63.3 -31.4 5.0 0.043 0.227 A:Q04631:0.226
 HOH
 2.962
 OG
 O
1tn7 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 SER B:272 B:772 30.0 0.261 H -68.4 -32.3 7.0 0.061 0.2 A:Q04631:0.2
 HOH
 2.690
 O
 O
1tn8 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 SER B:272 B:772 28.0 0.243 H -65.9 -31.5 7.0 0.061 0.182 A:Q04631:0.183
 HOH
 2.815
 O
 O
3dpy 2 Q02293 96.57 0.0 X-RAY
 2008-09-30 SER B:272 B:272 29.0 0.252 H -68.6 -31.6 9.0 0.078 0.174 A:Q04631:0.174
 HOH
 6.378
 N
 O
3e30 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 SER B:272 B:272 31.0 0.27 H -66.8 -32.4 8.0 0.07 0.2 A:Q04631:0.2
 HOH
 2.745
 O
 O
3e32 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 SER B:272 B:272 32.0 0.278 H -65.8 -33.3 11.0 0.096 0.182 A:Q04631:0.183
 HOH
 2.634
 O
 O
3e33 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 SER B:272 B:272 28.0 0.243 H -69.4 -30.7 7.0 0.061 0.182 A:Q04631:0.183
 HOH
 2.802
 O
 O
3e34 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 SER B:272 B:272 32.0 0.278 H -71.4 -29.9 8.0 0.07 0.208 A:Q04631:0.209
 HOH
 2.687
 O
 O
3ksl 2 Q02293 96.57 0.0 X-RAY
 2009-12-22 SER B:272 B:272 34.0 0.296 H -68.3 -33.2 14.0 0.122 0.174 A:Q5RKJ4:0.174
 HOH
 2.718
 O
 O
3ksq 2 Q02293 96.57 0.0 X-RAY
 2010-01-26 SER B:272 B:272 30.0 0.261 H -68.2 -33.4 13.0 0.113 0.148 A:Q5RKJ4:0.148
 HOH
 2.800
 O
 O
7rn5 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 SER B:272 B:272 37.0 0.322 H -69.9 -31.3 12.0 0.104 0.218 A:Q04631:0.217
 HOH
 2.864
 HB2
 O
7rni 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 SER B:272 B:272 35.0 0.304 H -68.5 -32.8 16.0 0.139 0.165 A:Q04631:0.165
 HOH
 2.587
 HA
 O
2zir 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 SER B:275 B:272 30.0 0.261 H -68.2 -35.1 11.0 0.096 0.165 A:Q04631:0.165
 HOH
 2.937
 O
 O
2zis 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 SER B:275 B:272 29.0 0.252 H -69.3 -30.4 10.0 0.087 0.165 A:Q04631:0.165
 HOH
 2.807
 OG
 O
3euv 2 Q02293 97.65 0.0 X-RAY
 2009-07-07 SER B:272 B:272 30.0 0.261 H -71.5 -39.2 26.0 0.226 0.035 A:Q04631:0.035
 HOH
 7.145
 OG
 O
1n95 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 SER B:251 B:272 25.0 0.217 H -56.6 -32.1 13.0 0.113 0.104 A:Q04631:0.104
1n9a 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 SER B:251 B:272 25.0 0.217 H -55.5 -31.9 13.0 0.113 0.104 A:Q04631:0.104
1ni1 2 Q02293 98.26 0.0 X-RAY
 2004-04-06 SER B:251 B:272 23.0 0.2 H -77.6 -36.0 7.0 0.061 0.139 A:Q04631:0.139
1nl4 2 Q02293 98.25 0.0 X-RAY
 2003-02-11 SER B:250 B:272 26.0 0.226 H -59.7 -30.7 13.0 0.113 0.113 A:Q04631:0.113
2bed 2 Q02293 98.25 0.0 X-RAY
 2006-08-08 SER B:250 B:272 29.0 0.252 H -67.0 -36.3 13.0 0.113 0.139 A:Q04631:0.139
 HOH
 3.013
 OG
 O
2r2l 2 Q02293 98.25 0.0 X-RAY
 2008-03-11 SER B:250 B:272 34.0 0.296 H -71.2 -29.0 15.0 0.13 0.166 A:Q5RKJ4:0.165
 HOH
 2.865
 OG
 O
1ft2 2 Q02293 98.25 0.0 X-RAY
 1998-11-04 SER B:251 B:272 26.0 0.226 H -63.2 -36.4 10.0 0.087 0.139 A:Q04631:0.139
1n94 2 Q02293 98.24 0.0 X-RAY
 2003-01-07 SER B:251 B:272 54.0 0.47 H -69.2 -19.6 25.0 0.217 0.253 A:Q04631:0.252
1x81 2 Q02293 98.24 0.0 X-RAY
 2004-12-21 SER B:251 B:272 32.0 0.278 H -71.3 -16.2 9.0 0.078 0.2 A:Q04631:0.2

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p49356-f1 1 P49356 100.0 0.0 SER A:272 A:272 32.0 0.278 H -66.4 -35.3