Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 65519973 . A C CCDS9769.1:NM_002028.3:c.973Atg>Ctg_NP_002019.1:p.325M>L Homo sapiens farnesyltransferase, CAAX box, beta (FNTB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1jcq 2 P49356 100.0 0.0 X-RAY
 2001-11-02 MET B:325 B:325 135.0 0.73 S -110.3 12.4 135.0 0.73 0.0 HOH
 2.935
 CG
 O
1ld7 2 P49356 100.0 0.0 X-RAY
 2002-06-19 MET B:325 B:825 134.0 0.724 S -114.0 11.8 134.0 0.724 0.0 HOH
 2.834
 CG
 O
1ld8 2 P49356 100.0 0.0 X-RAY
 2002-06-19 MET B:325 B:825 132.0 0.714 S -113.0 16.4 132.0 0.714 0.0 HOH
 2.897
 O
 O
1mzc 2 P49356 100.0 0.0 X-RAY
 2003-07-08 MET B:325 B:825 134.0 0.724 S -112.6 14.9 134.0 0.724 0.0 HOH
 2.903
 O
 O
1s63 2 P49356 100.0 0.0 X-RAY
 2004-07-27 MET B:325 B:325 130.0 0.703 S -111.3 14.7 130.0 0.703 0.0 HOH
 2.891
 CG
 O
1sa4 2 P49356 100.0 0.0 X-RAY
 2004-06-08 MET B:325 B:325 132.0 0.714 S -109.6 9.8 132.0 0.714 0.0 HOH
 3.961
 CA
 O
1tn6 2 P49356 100.0 0.0 X-RAY
 2004-11-02 MET B:325 B:825 145.0 0.784 S -111.0 13.4 145.0 0.784 0.0 HOH
 2.895
 O
 O
2f0y 2 P49356 100.0 0.0 X-RAY
 2006-11-14 MET B:325 B:325 79.0 0.427 S -105.2 -6.1 79.0 0.427 0.0 HOH
 3.189
 N
 O
2h6f 2 P49356 100.0 0.0 X-RAY
 2006-08-29 MET B:325 B:825 135.0 0.73 S -111.9 15.5 135.0 0.73 0.0 HOH
 2.930
 O
 O
2iej 2 P49356 100.0 0.0 X-RAY
 2007-01-23 MET B:325 B:825 139.0 0.751 S -105.3 12.9 139.0 0.751 0.0 HOH
 3.844
 CG
 O
3e37 2 P49356 100.0 0.0 X-RAY
 2009-03-10 MET B:325 B:327 142.0 0.768 S -102.4 14.4 142.0 0.768 0.0 HOH
 2.918
 O
 O
2h6h 2 P49356 99.77 0.0 X-RAY
 2006-08-29 MET B:325 B:825 137.0 0.741 S -110.9 14.6 137.0 0.741 0.0 HOH
 2.892
 O
 O
2h6g 2 P49356 99.77 0.0 X-RAY
 2006-08-29 MET B:325 B:825 135.0 0.73 S -112.0 14.5 135.0 0.73 0.0 HOH
 2.956
 O
 O
2h6i 2 P49356 99.54 0.0 X-RAY
 2006-08-29 MET B:325 B:825 136.0 0.735 S -115.8 18.1 136.0 0.735 0.0 HOH
 7.367
 O
 O
1o1r 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 MET B:325 B:325 108.0 0.584 S -110.5 10.5 108.0 0.584 0.0 HOH
 3.347
 CE
 O
1o1s 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 MET B:325 B:325 120.0 0.649 S -106.3 3.6 120.0 0.649 0.0 HOH
 3.249
 N
 O
1o1t 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 MET B:325 B:325 119.0 0.643 S -118.1 15.4 119.0 0.643 0.0 HOH
 3.319
 O
 O
3eu5 2 Q02293 98.12 0.0 X-RAY
 2009-07-07 MET B:325 B:325 121.0 0.654 S -117.8 9.5 121.0 0.654 0.0 HOH
 4.930
 N
 O
4gtm 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 MET B:325 B:325 127.0 0.686 S -105.6 4.9 127.0 0.686 0.0 HOH
 2.793
 CE
 O
4gto 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 MET B:325 B:325 129.0 0.697 S -103.3 6.5 129.0 0.697 0.0 HOH
 3.246
 N
 O
4gtp 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 MET B:325 B:325 115.0 0.622 S -120.1 28.5 115.0 0.622 0.0 HOH
 5.008
 N
 O
4gtq 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 MET B:325 B:325 127.0 0.686 S -102.6 10.8 127.0 0.686 0.0 HOH
 3.539
 CA
 O
4gtr 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 MET B:325 B:325 123.0 0.665 S -104.5 2.3 123.0 0.665 0.0 HOH
 3.755
 CA
 O
3pz4 2 Q02293 98.11 0.0 X-RAY
 2011-05-11 MET B:324 B:325 109.0 0.589 S -111.4 4.7 109.0 0.589 0.0 HOH
 3.255
 N
 O
1d8d 2 Q02293 96.57 0.0 X-RAY
 2000-02-09 MET B:325 B:325 85.0 0.459 S -106.9 6.7 85.0 0.459 0.0 HOH
 4.707
 N
 O
1d8e 2 Q02293 96.57 0.0 X-RAY
 2000-03-20 MET B:325 B:325 84.0 0.454 S -115.6 4.5 84.0 0.454 0.0 HOH
 5.175
 N
 O
1fpp 1 Q02293 96.57 0.0 X-RAY
 1999-06-08 MET A:325 B:325 121.0 0.654 S -118.6 22.8 121.0 0.654 0.0 HOH
 9.021
 N
 O
1ft1 2 Q02293 96.57 0.0 X-RAY
 1998-03-18 MET B:325 B:325 119.0 0.643 S -106.7 13.6 119.0 0.643 0.0 HOH
 5.658
 N
 O
1jcr 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 MET B:325 B:325 77.0 0.416 S -113.6 16.1 77.0 0.416 0.0 HOH
 5.136
 N
 O
1jcs 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 MET B:325 B:325 78.0 0.422 S -109.0 11.2 78.0 0.422 0.0 HOH
 4.502
 N
 O
1kzo 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 MET B:325 B:325 80.0 0.432 S -115.2 14.1 80.0 0.432 0.0 HOH
 2.784
 N
 O
1kzp 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 MET B:325 B:325 76.0 0.411 S -111.5 14.0 76.0 0.411 0.0 HOH
 4.735
 N
 O
1o5m 2 Q02293 96.57 0.0 X-RAY
 2003-10-21 MET B:325 B:325 116.0 0.627 S -116.6 13.9 116.0 0.627 0.0 HOH
 3.223
 O
 O
1qbq 2 Q02293 96.57 0.0 X-RAY
 1999-06-18 MET B:325 B:325 105.0 0.568 S -111.8 11.1 105.0 0.568 0.0 HOH
 9.117
 N
 O
1sa5 2 Q02293 96.57 0.0 X-RAY
 2004-06-08 MET B:325 B:325 74.0 0.4 S -120.7 16.7 74.0 0.4 0.0 HOH
 4.946
 N
 O
1tn7 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 MET B:325 B:825 80.0 0.432 S -113.1 13.1 80.0 0.432 0.0 HOH
 5.177
 N
 O
1tn8 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 MET B:325 B:825 74.0 0.4 S -113.6 16.6 74.0 0.4 0.0 HOH
 4.859
 N
 O
3dpy 2 Q02293 96.57 0.0 X-RAY
 2008-09-30 MET B:325 B:325 79.0 0.427 S -110.2 13.1 79.0 0.427 0.0
3e30 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 MET B:325 B:325 78.0 0.422 S -113.2 9.8 78.0 0.422 0.0 HOH
 3.749
 N
 O
3e32 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 MET B:325 B:325 80.0 0.432 S -110.9 11.6 80.0 0.432 0.0 HOH
 4.649
 O
 O
3e33 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 MET B:325 B:325 78.0 0.422 S -112.2 14.3 78.0 0.422 0.0 HOH
 5.270
 N
 O
3e34 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 MET B:325 B:325 72.0 0.389 S -113.8 16.6 72.0 0.389 0.0 HOH
 3.440
 CE
 O
3ksl 2 Q02293 96.57 0.0 X-RAY
 2009-12-22 MET B:325 B:325 127.0 0.686 S -107.8 5.0 127.0 0.686 0.0 HOH
 3.278
 N
 O
3ksq 2 Q02293 96.57 0.0 X-RAY
 2010-01-26 MET B:325 B:325 124.0 0.67 S -110.3 3.9 124.0 0.67 0.0 HOH
 3.027
 O
 O
7rn5 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 MET B:325 B:325 136.0 0.735 S -104.3 14.2 136.0 0.735 0.0 HOH
 6.101
 N
 O
7rni 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 MET B:325 B:325 139.0 0.751 S -107.3 15.3 139.0 0.751 0.0 HOH
 2.704
 O
 O
2zir 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 MET B:328 B:325 93.0 0.503 S -106.8 0.3 93.0 0.503 0.0 HOH
 2.974
 CE
 O
2zis 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 MET B:328 B:325 93.0 0.503 S -104.3 -6.4 93.0 0.503 0.0 GOL
HOH
 9.590
5.217
 O
N
 O3
O
3euv 2 Q02293 97.65 0.0 X-RAY
 2009-07-07 MET B:325 B:325 111.0 0.6 S -132.8 16.7 111.0 0.6 0.0 HOH
 2.668
 O
 O
1n95 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 MET B:304 B:325 106.0 0.573 S -110.8 9.7 106.0 0.573 0.0
1n9a 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 MET B:304 B:325 105.0 0.568 S -112.4 9.6 105.0 0.568 0.0
1ni1 2 Q02293 98.26 0.0 X-RAY
 2004-04-06 MET B:304 B:325 105.0 0.568 S -145.8 7.8 105.0 0.568 0.0
1nl4 2 Q02293 98.25 0.0 X-RAY
 2003-02-11 MET B:303 B:325 104.0 0.562 S -117.4 13.3 104.0 0.562 0.0
2bed 2 Q02293 98.25 0.0 X-RAY
 2006-08-08 MET B:303 B:325 116.0 0.627 S -87.6 14.9 116.0 0.627 0.0 HOH
 7.439
 O
 O
2r2l 2 Q02293 98.25 0.0 X-RAY
 2008-03-11 MET B:303 B:325 122.0 0.659 S -121.8 16.8 122.0 0.659 0.0 HOH
 3.005
 O
 O
1ft2 2 Q02293 98.25 0.0 X-RAY
 1998-11-04 MET B:304 B:325 117.0 0.632 S -107.2 13.3 117.0 0.632 0.0
1n94 2 Q02293 98.24 0.0 X-RAY
 2003-01-07 MET B:304 B:325 121.0 0.654 S -137.1 5.4 121.0 0.654 0.0
1x81 2 Q02293 98.24 0.0 X-RAY
 2004-12-21 MET B:304 B:325 120.0 0.649 S -101.6 -9.7 120.0 0.649 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p49356-f1 1 P49356 100.0 0.0 MET A:325 A:325 95.0 0.514 S -99.6 5.3