Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 65521354 . G A CCDS9769.1:NM_002028.3:c.1129Ggc>Agc_NP_002019.1:p.377G>S Homo sapiens farnesyltransferase, CAAX box, beta (FNTB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1jcq 2 P49356 100.0 0.0 X-RAY
 2001-11-02 GLY B:377 B:377 29.0 0.387 E -160.7 135.0 29.0 0.387 0.0 HOH
 4.236
 O
 O
1ld7 2 P49356 100.0 0.0 X-RAY
 2002-06-19 GLY B:377 B:877 34.0 0.453 E -155.2 127.8 34.0 0.453 0.0 HOH
 3.230
 CA
 O
1ld8 2 P49356 100.0 0.0 X-RAY
 2002-06-19 GLY B:377 B:877 25.0 0.333 E -155.7 124.0 25.0 0.333 0.0 HOH
 2.900
 O
 O
1mzc 2 P49356 100.0 0.0 X-RAY
 2003-07-08 GLY B:377 B:877 36.0 0.48 E -151.3 129.7 36.0 0.48 0.0 HOH
 3.163
 O
 O
1s63 2 P49356 100.0 0.0 X-RAY
 2004-07-27 GLY B:377 B:377 35.0 0.467 E -153.3 132.2 35.0 0.467 0.0 HOH
 2.948
 O
 O
1sa4 2 P49356 100.0 0.0 X-RAY
 2004-06-08 GLY B:377 B:377 32.0 0.427 E -152.9 127.4 32.0 0.427 0.0 HOH
 3.051
 O
 O
1tn6 2 P49356 100.0 0.0 X-RAY
 2004-11-02 GLY B:377 B:877 34.0 0.453 E -154.2 135.8 34.0 0.453 0.0 HOH
 3.393
 O
 O
2f0y 2 P49356 100.0 0.0 X-RAY
 2006-11-14 GLY B:377 B:377 23.0 0.307 -127.9 169.4 23.0 0.307 0.0 HOH
 3.861
 N
 O
2h6f 2 P49356 100.0 0.0 X-RAY
 2006-08-29 GLY B:377 B:877 37.0 0.493 E -152.4 133.6 37.0 0.493 0.0 HOH
 3.247
 CA
 O
2iej 2 P49356 100.0 0.0 X-RAY
 2007-01-23 GLY B:377 B:877 37.0 0.493 E -148.9 135.6 37.0 0.493 0.0 HOH
 3.159
 O
 O
3e37 2 P49356 100.0 0.0 X-RAY
 2009-03-10 GLY B:377 B:379 33.0 0.44 E -150.4 134.9 33.0 0.44 0.0 HOH
 3.250
 C
 O
2h6h 2 P49356 99.77 0.0 X-RAY
 2006-08-29 GLY B:377 B:877 37.0 0.493 E -152.3 134.6 37.0 0.493 0.0 HOH
 3.255
 CA
 O
2h6g 2 P49356 99.77 0.0 X-RAY
 2006-08-29 GLY B:377 B:877 36.0 0.48 E -152.5 134.1 36.0 0.48 0.0 HOH
 3.265
 CA
 O
2h6i 2 P49356 99.54 0.0 X-RAY
 2006-08-29 GLY B:377 B:877 37.0 0.493 E -150.7 138.1 37.0 0.493 0.0
1o1r 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 GLY B:377 B:377 26.0 0.347 E -166.3 140.6 26.0 0.347 0.0 HOH
 2.915
 O
 O
1o1s 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 GLY B:377 B:377 27.0 0.36 E -166.7 134.5 27.0 0.36 0.0 HOH
 2.755
 O
 O
1o1t 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 GLY B:377 B:377 26.0 0.347 E -170.2 139.2 26.0 0.347 0.0 HOH
 3.011
 O
 O
3eu5 2 Q02293 98.12 0.0 X-RAY
 2009-07-07 GLY B:377 B:377 30.0 0.4 E -159.0 139.8 30.0 0.4 0.0 HOH
 5.648
 N
 O
4gtm 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 GLY B:377 B:377 36.0 0.48 E -157.1 118.2 36.0 0.48 0.0 HOH
 4.380
 O
 O
4gto 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 GLY B:377 B:377 43.0 0.573 E -155.1 121.4 43.0 0.573 0.0 HOH
 3.478
 CA
 O
4gtp 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 GLY B:377 B:377 30.0 0.4 E -123.0 158.0 30.0 0.4 0.0 HOH
 5.608
 N
 O
4gtq 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 GLY B:377 B:377 41.0 0.547 E -154.1 112.1 41.0 0.547 0.0 HOH
 2.644
 N
 O
4gtr 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 GLY B:377 B:377 28.0 0.373 E -140.2 139.4 28.0 0.373 0.0 HOH
 4.770
 N
 O
3pz4 2 Q02293 98.11 0.0 X-RAY
 2011-05-11 GLY B:376 B:377 26.0 0.347 -122.9 157.1 26.0 0.347 0.0 HOH
 2.855
 C
 O
1d8d 2 Q02293 96.57 0.0 X-RAY
 2000-02-09 GLY B:377 B:377 37.0 0.493 E -152.8 118.4 37.0 0.493 0.0 HOH
 4.619
 N
 O
1d8e 2 Q02293 96.57 0.0 X-RAY
 2000-03-20 GLY B:377 B:377 36.0 0.48 E -156.7 116.9 36.0 0.48 0.0 HOH
 5.912
 O
 O
1fpp 1 Q02293 96.57 0.0 X-RAY
 1999-06-08 GLY A:377 B:377 29.0 0.387 B -167.7 128.8 29.0 0.387 0.0 HOH
 8.866
 O
 O
1ft1 2 Q02293 96.57 0.0 X-RAY
 1998-03-18 GLY B:377 B:377 28.0 0.373 E -161.7 133.7 28.0 0.373 0.0 HOH
 3.667
 O
 O
1jcr 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 GLY B:377 B:377 35.0 0.467 E -143.3 130.8 35.0 0.467 0.0 HOH
 4.414
 N
 O
1jcs 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 GLY B:377 B:377 35.0 0.467 E -154.1 112.5 35.0 0.467 0.0 HOH
 4.518
 N
 O
1kzo 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 GLY B:377 B:377 30.0 0.4 E -146.3 137.3 30.0 0.4 0.0 HOH
 4.435
 N
 O
1kzp 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 GLY B:377 B:377 36.0 0.48 E -148.1 128.9 36.0 0.48 0.0 HOH
 4.337
 N
 O
1o5m 2 Q02293 96.57 0.0 X-RAY
 2003-10-21 GLY B:377 B:377 31.0 0.413 E -171.0 128.2 31.0 0.413 0.0 HOH
 2.903
 O
 O
1qbq 2 Q02293 96.57 0.0 X-RAY
 1999-06-18 GLY B:377 B:377 24.0 0.32 -155.3 159.3 24.0 0.32 0.0 HOH
 6.015
 N
 O
1sa5 2 Q02293 96.57 0.0 X-RAY
 2004-06-08 GLY B:377 B:377 36.0 0.48 E -148.0 120.5 36.0 0.48 0.0 HOH
 4.597
 O
 O
1tn7 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 GLY B:377 B:877 32.0 0.427 E -161.1 115.2 32.0 0.427 0.0 HOH
 4.489
 N
 O
1tn8 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 GLY B:377 B:877 34.0 0.453 E -158.4 108.5 34.0 0.453 0.0 HOH
 4.956
 O
 O
3dpy 2 Q02293 96.57 0.0 X-RAY
 2008-09-30 GLY B:377 B:377 40.0 0.533 E -143.8 110.6 40.0 0.533 0.0
3e30 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 GLY B:377 B:377 30.0 0.4 E -163.6 130.6 30.0 0.4 0.0 HOH
 4.634
 N
 O
3e32 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 GLY B:377 B:377 32.0 0.427 E -156.5 132.3 32.0 0.427 0.0 HOH
 5.769
 N
 O
3e33 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 GLY B:377 B:377 34.0 0.453 E -151.0 120.8 34.0 0.453 0.0 HOH
 5.349
 N
 O
3e34 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 GLY B:377 B:377 32.0 0.427 E -155.9 124.4 32.0 0.427 0.0 HOH
 4.489
 N
 O
3ksl 2 Q02293 96.57 0.0 X-RAY
 2009-12-22 GLY B:377 B:377 28.0 0.373 E -153.2 137.1 28.0 0.373 0.0 HOH
 2.625
 O
 O
3ksq 2 Q02293 96.57 0.0 X-RAY
 2010-01-26 GLY B:377 B:377 30.0 0.4 E -161.1 129.2 30.0 0.4 0.0 HOH
 4.591
 O
 O
7rn5 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 GLY B:377 B:377 31.0 0.413 E -161.3 131.8 31.0 0.413 0.0 HOH
 2.708
 O
 O
7rni 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 GLY B:377 B:377 30.0 0.4 E -153.9 132.3 30.0 0.4 0.0 HOH
 2.752
 O
 O
2zir 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 GLY B:380 B:377 34.0 0.453 E -162.9 115.6 34.0 0.453 0.0 GOL
HOH
 3.589
4.908
 N
N
 O2
O
2zis 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 GLY B:380 B:377 31.0 0.413 E -162.5 116.3 31.0 0.413 0.0 GOL
HOH
 2.862
4.018
 O
O
 O3
O
3euv 2 Q02293 97.65 0.0 X-RAY
 2009-07-07 GLY B:377 B:377 32.0 0.427 E -154.1 134.3 32.0 0.427 0.0 HOH
 4.521
 N
 O
1n95 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 GLY B:356 B:377 25.0 0.333 -157.4 161.6 25.0 0.333 0.0
1n9a 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 GLY B:356 B:377 26.0 0.347 -156.2 161.3 26.0 0.347 0.0
1ni1 2 Q02293 98.26 0.0 X-RAY
 2004-04-06 GLY B:356 B:377 15.0 0.2 -157.7 167.5 15.0 0.2 0.0
1nl4 2 Q02293 98.25 0.0 X-RAY
 2003-02-11 GLY B:355 B:377 23.0 0.307 -158.8 166.8 23.0 0.307 0.0
2bed 2 Q02293 98.25 0.0 X-RAY
 2006-08-08 GLY B:355 B:377 22.0 0.293 E -137.7 170.2 22.0 0.293 0.0 HOH
 4.651
 N
 O
2r2l 2 Q02293 98.25 0.0 X-RAY
 2008-03-11 GLY B:355 B:377 30.0 0.4 E -168.9 129.3 30.0 0.4 0.0 HOH
 2.758
 O
 O
1ft2 2 Q02293 98.25 0.0 X-RAY
 1998-11-04 GLY B:356 B:377 35.0 0.467 E -163.9 127.0 35.0 0.467 0.0
1n94 2 Q02293 98.24 0.0 X-RAY
 2003-01-07 GLY B:356 B:377 38.0 0.507 -154.3 47.7 38.0 0.507 0.0
1x81 2 Q02293 98.24 0.0 X-RAY
 2004-12-21 GLY B:356 B:377 25.0 0.333 E -175.7 138.0 25.0 0.333 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p49356-f1 1 P49356 100.0 0.0 GLY A:377 A:377 36.0 0.48 E -146.0 125.5