Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 65521396 . G A CCDS9769.1:NM_002028.3:c.1171Gaa>Aaa_NP_002019.1:p.391E>K Homo sapiens farnesyltransferase, CAAX box, beta (FNTB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1jcq 2 P49356 100.0 0.0 X-RAY
 2001-11-02 GLU B:391 B:391 126.0 0.663 G -62.2 -14.7 126.0 0.663 0.0 HOH
 3.396
 C
 O
1ld7 2 P49356 100.0 0.0 X-RAY
 2002-06-19 GLU B:391 B:891 126.0 0.663 G -63.2 -10.7 126.0 0.663 0.0 HOH
 3.564
 C
 O
1ld8 2 P49356 100.0 0.0 X-RAY
 2002-06-19 GLU B:391 B:891 118.0 0.621 G -64.3 -13.1 118.0 0.621 0.0 HOH
 3.335
 O
 O
1mzc 2 P49356 100.0 0.0 X-RAY
 2003-07-08 GLU B:391 B:891 125.0 0.658 G -65.5 -8.2 125.0 0.658 0.0 HOH
 3.475
 O
 O
1s63 2 P49356 100.0 0.0 X-RAY
 2004-07-27 GLU B:391 B:391 120.0 0.632 G -66.7 -9.0 120.0 0.632 0.0 HOH
 3.374
 O
 O
1sa4 2 P49356 100.0 0.0 X-RAY
 2004-06-08 GLU B:391 B:391 124.0 0.653 G -63.4 -10.2 124.0 0.653 0.0 HOH
 3.509
 O
 O
1tn6 2 P49356 100.0 0.0 X-RAY
 2004-11-02 GLU B:391 B:891 124.0 0.653 G -63.7 -9.6 124.0 0.653 0.0 HOH
 3.487
 O
 O
2f0y 2 P49356 100.0 0.0 X-RAY
 2006-11-14 GLU B:391 B:391 124.0 0.653 T -69.5 -27.0 124.0 0.653 0.0 HOH
 3.055
 CA
 O
2h6f 2 P49356 100.0 0.0 X-RAY
 2006-08-29 GLU B:391 B:891 123.0 0.647 G -63.2 -12.6 123.0 0.647 0.0 HOH
 3.266
 O
 O
2iej 2 P49356 100.0 0.0 X-RAY
 2007-01-23 GLU B:391 B:891 125.0 0.658 G -65.7 -13.5 125.0 0.658 0.0 HOH
 3.383
 O
 O
3e37 2 P49356 100.0 0.0 X-RAY
 2009-03-10 GLU B:391 B:393 124.0 0.653 G -63.1 -10.7 124.0 0.653 0.0 HOH
 3.026
 OE1
 O
2h6h 2 P49356 99.77 0.0 X-RAY
 2006-08-29 GLU B:391 B:891 121.0 0.637 G -63.6 -11.4 121.0 0.637 0.0 HOH
 3.316
 O
 O
2h6g 2 P49356 99.77 0.0 X-RAY
 2006-08-29 GLU B:391 B:891 119.0 0.626 G -61.9 -11.3 119.0 0.626 0.0 HOH
 3.398
 O
 O
2h6i 2 P49356 99.54 0.0 X-RAY
 2006-08-29 GLU B:391 B:891 121.0 0.637 G -58.1 -22.2 121.0 0.637 0.0 HOH
 3.261
 O
 O
1o1r 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 GLU B:391 B:391 120.0 0.632 G -72.4 -8.9 120.0 0.632 0.0 HOH
 3.150
 O
 O
1o1s 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 GLU B:391 B:391 120.0 0.632 G -75.5 -2.5 120.0 0.632 0.0 HOH
 2.957
 O
 O
1o1t 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 GLU B:391 B:391 122.0 0.642 G -74.2 -5.3 122.0 0.642 0.0 HOH
 3.073
 O
 O
3eu5 2 Q02293 98.12 0.0 X-RAY
 2009-07-07 GLU B:391 B:391 123.0 0.647 G -74.4 -6.8 123.0 0.647 0.0 HOH
 4.680
 N
 O
4gtm 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 GLU B:391 B:391 123.0 0.647 G -66.5 -16.0 123.0 0.647 0.0 HOH
 2.707
 O
 O
4gto 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 GLU B:391 B:391 124.0 0.653 G -71.0 -13.6 124.0 0.653 0.0 HOH
 2.570
 O
 O
4gtp 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 GLU B:391 B:391 131.0 0.689 G -73.1 -12.5 131.0 0.689 0.0 HOH
 5.117
 N
 O
4gtq 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 GLU B:391 B:391 132.0 0.695 G -61.5 -13.1 132.0 0.695 0.0 HOH
 7.224
 C
 O
4gtr 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 GLU B:391 B:391 121.0 0.637 G -63.1 -20.3 121.0 0.637 0.0 HOH
 2.709
 OE2
 O
3pz4 2 Q02293 98.11 0.0 X-RAY
 2011-05-11 GLU B:390 B:391 126.0 0.663 G -68.2 -13.1 126.0 0.663 0.0 HOH
 3.064
 O
 O
1d8d 2 Q02293 96.57 0.0 X-RAY
 2000-02-09 GLU B:391 B:391 119.0 0.626 G -69.4 -14.8 119.0 0.626 0.0 HOH
 3.335
 O
 O
1d8e 2 Q02293 96.57 0.0 X-RAY
 2000-03-20 GLU B:391 B:391 125.0 0.658 G -71.7 -14.2 125.0 0.658 0.0 HOH
 7.510
 C
 O
1fpp 1 Q02293 96.57 0.0 X-RAY
 1999-06-08 GLU A:391 B:391 111.0 0.584 G -83.4 -11.3 111.0 0.584 0.0
1ft1 2 Q02293 96.57 0.0 X-RAY
 1998-03-18 GLU B:391 B:391 128.0 0.674 G -63.3 -14.7 128.0 0.674 0.0 HOH
 2.639
 O
 O
1jcr 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 GLU B:391 B:391 123.0 0.647 G -65.3 -14.7 123.0 0.647 0.0 HOH
 3.200
 O
 O
1jcs 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 GLU B:391 B:391 119.0 0.626 G -70.0 -12.6 119.0 0.626 0.0 HOH
 3.383
 O
 O
1kzo 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 GLU B:391 B:391 122.0 0.642 G -71.8 -9.4 122.0 0.642 0.0 HOH
 3.254
 O
 O
1kzp 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 GLU B:391 B:391 125.0 0.658 G -71.4 -13.0 125.0 0.658 0.0 HOH
 3.219
 O
 O
1o5m 2 Q02293 96.57 0.0 X-RAY
 2003-10-21 GLU B:391 B:391 122.0 0.642 G -72.4 -6.3 122.0 0.642 0.0 HOH
 3.059
 O
 O
1qbq 2 Q02293 96.57 0.0 X-RAY
 1999-06-18 GLU B:391 B:391 123.0 0.647 G -81.0 -4.9 123.0 0.647 0.0 HOH
 3.284
 O
 O
1sa5 2 Q02293 96.57 0.0 X-RAY
 2004-06-08 GLU B:391 B:391 116.0 0.611 G -59.6 -11.9 116.0 0.611 0.0 HOH
 3.311
 O
 O
1tn7 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 GLU B:391 B:891 116.0 0.611 G -70.2 -12.3 116.0 0.611 0.0 HOH
 3.534
 C
 O
1tn8 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 GLU B:391 B:891 119.0 0.626 G -72.4 -14.0 119.0 0.626 0.0 HOH
 3.287
 O
 O
3dpy 2 Q02293 96.57 0.0 X-RAY
 2008-09-30 GLU B:391 B:391 124.0 0.653 G -76.2 -6.1 124.0 0.653 0.0 HOH
 7.018
 CB
 O
3e30 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 GLU B:391 B:391 121.0 0.637 G -70.7 -10.0 121.0 0.637 0.0 HOH
 3.475
 O
 O
3e32 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 GLU B:391 B:391 120.0 0.632 G -65.6 -13.2 120.0 0.632 0.0 HOH
 5.014
 N
 O
3e33 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 GLU B:391 B:391 117.0 0.616 G -65.8 -8.6 117.0 0.616 0.0 HOH
 5.707
 O
 O
3e34 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 GLU B:391 B:391 118.0 0.621 G -62.5 -11.7 118.0 0.621 0.0 HOH
 2.928
 OE1
 O
3ksl 2 Q02293 96.57 0.0 X-RAY
 2009-12-22 GLU B:391 B:391 122.0 0.642 G -65.1 -11.7 122.0 0.642 0.0 HOH
 3.500
 O
 O
3ksq 2 Q02293 96.57 0.0 X-RAY
 2010-01-26 GLU B:391 B:391 119.0 0.626 G -64.5 -10.7 119.0 0.626 0.0 HOH
 3.480
 O
 O
7rn5 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 GLU B:391 B:391 121.0 0.637 G -65.9 -9.4 121.0 0.637 0.0 HOH
 3.268
 HB2
 O
7rni 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 GLU B:391 B:391 118.0 0.621 G -64.0 -14.4 118.0 0.621 0.0 HOH
 3.327
 HB2
 O
2zir 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 GLU B:394 B:391 125.0 0.658 G -66.2 -4.8 125.0 0.658 0.0 HOH
 3.230
 O
 O
2zis 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 GLU B:394 B:391 125.0 0.658 G -71.2 -12.5 125.0 0.658 0.0 HOH
 3.419
 O
 O
3euv 2 Q02293 97.65 0.0 X-RAY
 2009-07-07 GLU B:391 B:391 129.0 0.679 G -70.0 -15.4 129.0 0.679 0.0 HOH
 9.443
 OE1
 O
1n95 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 GLU B:370 B:391 127.0 0.668 G -85.2 -4.4 127.0 0.668 0.0
1n9a 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 GLU B:370 B:391 126.0 0.663 G -86.2 -3.1 126.0 0.663 0.0
1ni1 2 Q02293 98.26 0.0 X-RAY
 2004-04-06 GLU B:370 B:391 117.0 0.616 G -84.4 -7.5 117.0 0.616 0.0
1nl4 2 Q02293 98.25 0.0 X-RAY
 2003-02-11 GLU B:369 B:391 124.0 0.653 G -77.5 -5.2 124.0 0.653 0.0
2bed 2 Q02293 98.25 0.0 X-RAY
 2006-08-08 GLU B:369 B:391 114.0 0.6 G -74.5 2.9 114.0 0.6 0.0 HOH
 3.145
 O
 O
2r2l 2 Q02293 98.25 0.0 X-RAY
 2008-03-11 GLU B:369 B:391 119.0 0.626 G -68.0 -4.6 119.0 0.626 0.0 HOH
 3.420
 O
 O
1ft2 2 Q02293 98.25 0.0 X-RAY
 1998-11-04 GLU B:370 B:391 123.0 0.647 G -66.8 -8.8 123.0 0.647 0.0
1n94 2 Q02293 98.24 0.0 X-RAY
 2003-01-07 GLU B:370 B:391 121.0 0.637 G -100.4 28.1 121.0 0.637 0.0
1x81 2 Q02293 98.24 0.0 X-RAY
 2004-12-21 GLU B:370 B:391 126.0 0.663 G -86.9 -4.8 126.0 0.663 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p49356-f1 1 P49356 100.0 0.0 GLU A:391 A:391 128.0 0.674 G -65.5 -6.6