Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 65527930 . C A CCDS9769.1:NM_002028.3:c.1214cCa>cAa_NP_002019.1:p.405P>Q Homo sapiens farnesyltransferase, CAAX box, beta (FNTB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1jcq 2 P49356 100.0 0.0 X-RAY
 2001-11-02 PRO B:405 B:405 43.0 0.297 H -63.2 -36.8 43.0 0.297 0.0 HOH
 6.381
 CG
 O
1ld7 2 P49356 100.0 0.0 X-RAY
 2002-06-19 PRO B:405 B:905 41.0 0.283 H -59.0 -37.0 41.0 0.283 0.0 HOH
 2.859
 O
 O
1ld8 2 P49356 100.0 0.0 X-RAY
 2002-06-19 PRO B:405 B:905 40.0 0.276 H -59.8 -34.5 40.0 0.276 0.0 HOH
 2.841
 O
 O
1mzc 2 P49356 100.0 0.0 X-RAY
 2003-07-08 PRO B:405 B:905 41.0 0.283 H -57.3 -36.3 41.0 0.283 0.0 HOH
 2.934
 O
 O
1s63 2 P49356 100.0 0.0 X-RAY
 2004-07-27 PRO B:405 B:405 40.0 0.276 H -58.4 -35.0 40.0 0.276 0.0 HOH
 2.671
 O
 O
1sa4 2 P49356 100.0 0.0 X-RAY
 2004-06-08 PRO B:405 B:405 41.0 0.283 H -60.8 -26.5 41.0 0.283 0.0 HOH
 2.744
 O
 O
1tn6 2 P49356 100.0 0.0 X-RAY
 2004-11-02 PRO B:405 B:905 41.0 0.283 H -58.1 -33.6 41.0 0.283 0.0 HOH
 2.803
 O
 O
2f0y 2 P49356 100.0 0.0 X-RAY
 2006-11-14 PRO B:405 B:405 40.0 0.276 H -51.7 -40.7 40.0 0.276 0.0 HOH
 3.795
 CG
 O
2h6f 2 P49356 100.0 0.0 X-RAY
 2006-08-29 PRO B:405 B:905 40.0 0.276 H -58.4 -33.5 40.0 0.276 0.0 HOH
 2.883
 O
 O
2iej 2 P49356 100.0 0.0 X-RAY
 2007-01-23 PRO B:405 B:905 40.0 0.276 H -60.1 -34.1 40.0 0.276 0.0 HOH
 2.920
 O
 O
3e37 2 P49356 100.0 0.0 X-RAY
 2009-03-10 PRO B:405 B:407 40.0 0.276 H -60.6 -32.7 40.0 0.276 0.0 HOH
 2.893
 O
 O
2h6h 2 P49356 99.77 0.0 X-RAY
 2006-08-29 PRO B:405 B:905 40.0 0.276 H -57.5 -33.8 40.0 0.276 0.0 HOH
 2.879
 O
 O
2h6g 2 P49356 99.77 0.0 X-RAY
 2006-08-29 PRO B:405 B:905 41.0 0.283 H -58.0 -35.7 41.0 0.283 0.0 HOH
 2.890
 O
 O
2h6i 2 P49356 99.54 0.0 X-RAY
 2006-08-29 PRO B:405 B:905 39.0 0.269 H -59.3 -37.7 39.0 0.269 0.0
1o1r 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 PRO B:405 B:405 40.0 0.276 H -47.9 -37.9 40.0 0.276 0.0 HOH
 2.669
 O
 O
1o1s 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 PRO B:405 B:405 40.0 0.276 H -50.3 -37.5 40.0 0.276 0.0 HOH
 2.667
 O
 O
1o1t 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 PRO B:405 B:405 40.0 0.276 H -50.6 -34.3 40.0 0.276 0.0 HOH
 2.715
 O
 O
3eu5 2 Q02293 98.12 0.0 X-RAY
 2009-07-07 PRO B:405 B:405 41.0 0.283 H -57.1 -43.1 41.0 0.283 0.0 HOH
 3.805
 CG
 O
4gtm 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 PRO B:405 B:405 43.0 0.297 H -52.0 -31.7 43.0 0.297 0.0 HOH
 2.553
 O
 O
4gto 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 PRO B:405 B:405 42.0 0.29 H -49.3 -35.0 42.0 0.29 0.0 HOH
 2.545
 O
 O
4gtp 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 PRO B:405 B:405 45.0 0.31 H -49.4 -39.7 45.0 0.31 0.0 HOH
 3.367
 CD
 O
4gtq 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 PRO B:405 B:405 47.0 0.324 H -50.0 -30.8 47.0 0.324 0.0 HOH
 5.617
 O
 O
4gtr 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 PRO B:405 B:405 39.0 0.269 H -52.6 -29.6 39.0 0.269 0.0 HOH
 3.732
 CD
 O
3pz4 2 Q02293 98.11 0.0 X-RAY
 2011-05-11 PRO B:404 B:405 45.0 0.31 H -52.7 -24.8 45.0 0.31 0.0 HOH
 3.969
 CD
 O
1d8d 2 Q02293 96.57 0.0 X-RAY
 2000-02-09 PRO B:405 B:405 38.0 0.262 H -53.8 -32.3 38.0 0.262 0.0 HOH
 2.686
 O
 O
1d8e 2 Q02293 96.57 0.0 X-RAY
 2000-03-20 PRO B:405 B:405 38.0 0.262 H -48.8 -39.1 38.0 0.262 0.0 HOH
 6.541
 CG
 O
1fpp 1 Q02293 96.57 0.0 X-RAY
 1999-06-08 PRO A:405 B:405 45.0 0.31 H -45.4 -42.0 45.0 0.31 0.0
1ft1 2 Q02293 96.57 0.0 X-RAY
 1998-03-18 PRO B:405 B:405 40.0 0.276 H -57.0 -31.8 40.0 0.276 0.0 HOH
 2.655
 O
 O
1jcr 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 PRO B:405 B:405 39.0 0.269 H -54.1 -31.8 39.0 0.269 0.0 HOH
 2.607
 O
 O
1jcs 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 PRO B:405 B:405 39.0 0.269 H -52.4 -34.7 39.0 0.269 0.0 HOH
 2.736
 O
 O
1kzo 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 PRO B:405 B:405 40.0 0.276 H -53.5 -34.5 40.0 0.276 0.0 HOH
 2.594
 O
 O
1kzp 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 PRO B:405 B:405 40.0 0.276 H -53.6 -31.8 40.0 0.276 0.0 HOH
 2.648
 O
 O
1o5m 2 Q02293 96.57 0.0 X-RAY
 2003-10-21 PRO B:405 B:405 39.0 0.269 H -52.7 -34.5 39.0 0.269 0.0 HOH
 2.727
 O
 O
1qbq 2 Q02293 96.57 0.0 X-RAY
 1999-06-18 PRO B:405 B:405 43.0 0.297 H -48.2 -23.7 43.0 0.297 0.0 HOH
 3.420
 CD
 O
1sa5 2 Q02293 96.57 0.0 X-RAY
 2004-06-08 PRO B:405 B:405 39.0 0.269 H -53.8 -33.0 39.0 0.269 0.0 HOH
 3.507
 CD
 O
1tn7 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 PRO B:405 B:905 39.0 0.269 H -55.8 -32.7 39.0 0.269 0.0 HOH
 3.357
 CG
 O
1tn8 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 PRO B:405 B:905 40.0 0.276 H -54.8 -27.8 40.0 0.276 0.0 HOH
 3.537
 CD
 O
3dpy 2 Q02293 96.57 0.0 X-RAY
 2008-09-30 PRO B:405 B:405 35.0 0.241 H -53.4 -31.7 35.0 0.241 0.0 HOH
 3.401
 CD
 O
3e30 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 PRO B:405 B:405 43.0 0.297 H -48.7 -40.3 43.0 0.297 0.0 HOH
 2.849
 O
 O
3e32 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 PRO B:405 B:405 41.0 0.283 H -52.0 -34.0 41.0 0.283 0.0 HOH
 2.913
 O
 O
3e33 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 PRO B:405 B:405 40.0 0.276 H -59.5 -28.9 40.0 0.276 0.0 HOH
 3.501
 CG
 O
3e34 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 PRO B:405 B:405 38.0 0.262 H -60.9 -30.3 38.0 0.262 0.0 HOH
 2.784
 O
 O
3ksl 2 Q02293 96.57 0.0 X-RAY
 2009-12-22 PRO B:405 B:405 41.0 0.283 H -53.2 -32.9 41.0 0.283 0.0 HOH
 2.777
 O
 O
3ksq 2 Q02293 96.57 0.0 X-RAY
 2010-01-26 PRO B:405 B:405 37.0 0.255 H -52.9 -31.4 37.0 0.255 0.0 HOH
 3.644
 CD
 O
7rn5 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 PRO B:405 B:405 41.0 0.283 H -53.7 -33.9 41.0 0.283 0.0 HOH
 2.822
 HG3
 O
7rni 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 PRO B:405 B:405 40.0 0.276 H -53.1 -35.8 40.0 0.276 0.0 ACE
HOH
 7.999
2.551
 HA
HG3
 O
O
2zir 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 PRO B:408 B:405 42.0 0.29 H -52.0 -34.5 42.0 0.29 0.0 GOL
HOH
 3.124
3.550
 CG
CD
 O1
O
2zis 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 PRO B:408 B:405 39.0 0.269 H -51.5 -32.8 39.0 0.269 0.0 GOL
HOH
 3.428
3.719
 CG
CD
 O1
O
3euv 2 Q02293 97.65 0.0 X-RAY
 2009-07-07 PRO B:405 B:405 41.0 0.283 H -54.4 -35.1 41.0 0.283 0.0 HOH
 3.591
 CD
 O
1n95 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 PRO B:384 B:405 44.0 0.303 H -50.2 -25.0 44.0 0.303 0.0
1n9a 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 PRO B:384 B:405 44.0 0.303 H -48.4 -24.9 44.0 0.303 0.0
1ni1 2 Q02293 98.26 0.0 X-RAY
 2004-04-06 PRO B:384 B:405 47.0 0.324 T -55.4 -19.4 47.0 0.324 0.0
1nl4 2 Q02293 98.25 0.0 X-RAY
 2003-02-11 PRO B:383 B:405 41.0 0.283 H -49.0 -29.4 41.0 0.283 0.0
2bed 2 Q02293 98.25 0.0 X-RAY
 2006-08-08 PRO B:383 B:405 42.0 0.29 H -47.8 -46.5 42.0 0.29 0.0 HOH
 3.546
 CD
 O
2r2l 2 Q02293 98.25 0.0 X-RAY
 2008-03-11 PRO B:383 B:405 41.0 0.283 H -54.8 -36.5 41.0 0.283 0.0 HOH
 2.702
 O
 O
1ft2 2 Q02293 98.25 0.0 X-RAY
 1998-11-04 PRO B:384 B:405 39.0 0.269 H -54.2 -35.9 39.0 0.269 0.0
1n94 2 Q02293 98.24 0.0 X-RAY
 2003-01-07 PRO B:384 B:405 35.0 0.241 H -53.6 -13.6 35.0 0.241 0.0
1x81 2 Q02293 98.24 0.0 X-RAY
 2004-12-21 PRO B:384 B:405 44.0 0.303 H -59.7 -19.2 44.0 0.303 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p49356-f1 1 P49356 100.0 0.0 PRO A:405 A:405 39.0 0.269 H -54.3 -34.7