Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr14 65527969 . A C CCDS9769.1:NM_002028.3:c.1253aAg>aCg_NP_002019.1:p.418K>T Homo sapiens farnesyltransferase, CAAX box, beta (FNTB), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1jcq 2 P49356 100.0 0.0 X-RAY
 2001-11-02 LYS B:418 B:418 69.0 0.345 S -113.7 156.6 69.0 0.345 0.0 HOH
 3.719
 NZ
 O
1ld7 2 P49356 100.0 0.0 X-RAY
 2002-06-19 LYS B:418 B:918 66.0 0.33 S -110.0 152.7 66.0 0.33 0.0 HOH
 3.033
 NZ
 O
1ld8 2 P49356 100.0 0.0 X-RAY
 2002-06-19 LYS B:418 B:918 63.0 0.315 S -108.1 153.0 63.0 0.315 0.0 HOH
 3.076
 NZ
 O
1mzc 2 P49356 100.0 0.0 X-RAY
 2003-07-08 LYS B:418 B:918 67.0 0.335 S -108.2 153.0 67.0 0.335 0.0 HOH
 3.606
 NZ
 O
1s63 2 P49356 100.0 0.0 X-RAY
 2004-07-27 LYS B:418 B:418 64.0 0.32 S -107.6 154.1 64.0 0.32 0.0 HOH
 3.406
 NZ
 O
1sa4 2 P49356 100.0 0.0 X-RAY
 2004-06-08 LYS B:418 B:418 65.0 0.325 S -109.6 153.1 65.0 0.325 0.0 HOH
 3.609
 NZ
 O
1tn6 2 P49356 100.0 0.0 X-RAY
 2004-11-02 LYS B:418 B:918 65.0 0.325 S -107.2 151.3 65.0 0.325 0.0 HOH
 2.847
 CE
 O
2f0y 2 P49356 100.0 0.0 X-RAY
 2006-11-14 LYS B:418 B:418 72.0 0.36 S -143.3 162.4 72.0 0.36 0.0 HOH
 5.280
 O
 O
2h6f 2 P49356 100.0 0.0 X-RAY
 2006-08-29 LYS B:418 B:918 63.0 0.315 S -105.0 152.4 63.0 0.315 0.0 HOH
 3.153
 O
 O
2iej 2 P49356 100.0 0.0 X-RAY
 2007-01-23 LYS B:418 B:918 65.0 0.325 S -109.9 149.7 65.0 0.325 0.0 HOH
 2.988
 CE
 O
3e37 2 P49356 100.0 0.0 X-RAY
 2009-03-10 LYS B:418 B:420 65.0 0.325 S -107.6 149.4 65.0 0.325 0.0 HOH
 2.592
 O
 O
2h6h 2 P49356 99.77 0.0 X-RAY
 2006-08-29 LYS B:418 B:918 66.0 0.33 S -106.6 151.5 66.0 0.33 0.0 HOH
 3.741
 CD
 O
2h6g 2 P49356 99.77 0.0 X-RAY
 2006-08-29 LYS B:418 B:918 66.0 0.33 S -105.6 151.7 66.0 0.33 0.0 HOH
 3.524
 NZ
 O
2h6i 2 P49356 99.54 0.0 X-RAY
 2006-08-29 LYS B:418 B:918 64.0 0.32 S -108.1 152.5 64.0 0.32 0.0 HOH
 8.183
 O
 O
1o1r 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 LYS B:418 B:418 54.0 0.27 S -90.5 149.6 54.0 0.27 0.0 HOH
 2.869
 NZ
 O
1o1s 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 LYS B:418 B:418 54.0 0.27 S -101.3 148.8 54.0 0.27 0.0 HOH
 2.843
 NZ
 O
1o1t 2 Q02293 98.12 0.0 X-RAY
 2003-05-06 LYS B:418 B:418 57.0 0.285 S -100.5 146.7 57.0 0.285 0.0 HOH
 2.991
 NZ
 O
3eu5 2 Q02293 98.12 0.0 X-RAY
 2009-07-07 LYS B:418 B:418 68.0 0.34 S -118.3 150.9 68.0 0.34 0.0 HOH
 7.448
 N
 O
4gtm 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 LYS B:418 B:418 68.0 0.34 S -106.7 156.4 68.0 0.34 0.0 HOH
 3.310
 O
 O
4gto 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 LYS B:418 B:418 73.0 0.365 S -104.5 159.2 73.0 0.365 0.0 HOH
 2.864
 O
 O
4gtp 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 LYS B:418 B:418 76.0 0.38 S -89.6 168.2 76.0 0.38 0.0 HOH
 4.652
 CE
 O
4gtq 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 LYS B:418 B:418 64.0 0.32 S -113.4 157.2 64.0 0.32 0.0 HOH
 5.268
 CE
 O
4gtr 2 Q02293 98.12 0.0 X-RAY
 2012-10-24 LYS B:418 B:418 65.0 0.325 S -100.2 153.6 65.0 0.325 0.0 HOH
 4.022
 CE
 O
3pz4 2 Q02293 98.11 0.0 X-RAY
 2011-05-11 LYS B:417 B:418 73.0 0.365 S -123.6 149.9 73.0 0.365 0.0 HOH
 3.993
 CE
 O
1d8d 2 Q02293 96.57 0.0 X-RAY
 2000-02-09 LYS B:418 B:418 69.0 0.345 S -95.5 157.8 69.0 0.345 0.0 HOH
 3.508
 CE
 O
1d8e 2 Q02293 96.57 0.0 X-RAY
 2000-03-20 LYS B:418 B:418 65.0 0.325 S -88.4 159.3 65.0 0.325 0.0 HOH
 7.944
 O
 O
1fpp 1 Q02293 96.57 0.0 X-RAY
 1999-06-08 LYS A:418 B:418 84.0 0.42 S -109.6 146.4 84.0 0.42 0.0
1ft1 2 Q02293 96.57 0.0 X-RAY
 1998-03-18 LYS B:418 B:418 61.0 0.305 S -101.5 143.9 61.0 0.305 0.0 HOH
 3.516
 CE
 O
1jcr 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 LYS B:418 B:418 63.0 0.315 S -91.4 154.8 63.0 0.315 0.0 HOH
 3.222
 CE
 O
1jcs 2 Q02293 96.57 0.0 X-RAY
 2001-11-02 LYS B:418 B:418 66.0 0.33 S -82.7 155.1 66.0 0.33 0.0 HOH
 3.232
 CE
 O
1kzo 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 LYS B:418 B:418 67.0 0.335 S -97.2 151.0 67.0 0.335 0.0 HOH
 3.740
 CE
 O
1kzp 2 Q02293 96.57 0.0 X-RAY
 2002-10-16 LYS B:418 B:418 66.0 0.33 S -88.2 158.9 66.0 0.33 0.0 HOH
 3.585
 CE
 O
1o5m 2 Q02293 96.57 0.0 X-RAY
 2003-10-21 LYS B:418 B:418 53.0 0.265 S -97.8 147.3 53.0 0.265 0.0 HOH
 3.036
 NZ
 O
1qbq 2 Q02293 96.57 0.0 X-RAY
 1999-06-18 LYS B:418 B:418 58.0 0.29 S -119.8 147.6 58.0 0.29 0.0 HOH
 4.568
 O
 O
1sa5 2 Q02293 96.57 0.0 X-RAY
 2004-06-08 LYS B:418 B:418 64.0 0.32 S -122.1 147.5 64.0 0.32 0.0 HOH
 4.701
 NZ
 O
1tn7 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 LYS B:418 B:918 64.0 0.32 S -96.0 156.3 64.0 0.32 0.0 HOH
 3.542
 NZ
 O
1tn8 2 Q02293 96.57 0.0 X-RAY
 2004-11-02 LYS B:418 B:918 67.0 0.335 S -92.8 159.2 67.0 0.335 0.0 HOH
 4.114
 CD
 O
3dpy 2 Q02293 96.57 0.0 X-RAY
 2008-09-30 LYS B:418 B:418 70.0 0.35 S -89.0 149.0 70.0 0.35 0.0
3e30 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 LYS B:418 B:418 63.0 0.315 S -98.4 154.1 63.0 0.315 0.0 HOH
 3.568
 CE
 O
3e32 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 LYS B:418 B:418 63.0 0.315 S -105.6 153.1 63.0 0.315 0.0 HOH
 3.861
 NZ
 O
3e33 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 LYS B:418 B:418 67.0 0.335 S -98.5 149.7 67.0 0.335 0.0 HOH
 4.371
 CD
 O
3e34 2 Q02293 96.57 0.0 X-RAY
 2009-03-10 LYS B:418 B:418 68.0 0.34 S -94.8 154.2 68.0 0.34 0.0 HOH
 3.297
 CE
 O
3ksl 2 Q02293 96.57 0.0 X-RAY
 2009-12-22 LYS B:418 B:418 67.0 0.335 S -94.5 145.6 67.0 0.335 0.0 HOH
 4.298
 CG
 O
3ksq 2 Q02293 96.57 0.0 X-RAY
 2010-01-26 LYS B:418 B:418 64.0 0.32 S -117.0 145.0 64.0 0.32 0.0 HOH
 4.456
 CG
 O
7rn5 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 LYS B:418 B:418 74.0 0.37 S -115.3 143.5 74.0 0.37 0.0 HOH
 2.746
 HE2
 O
7rni 2 Q02293 96.57 0.0 X-RAY
 2021-09-08 LYS B:418 B:418 74.0 0.37 S -108.0 147.0 74.0 0.37 0.0 HOH
 2.362
 HE3
 O
2zir 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 LYS B:421 B:418 56.0 0.28 S -134.8 148.8 56.0 0.28 0.0 HOH
 2.715
 NZ
 O
2zis 2 Q02293 96.57 0.0 X-RAY
 2009-02-24 LYS B:421 B:418 56.0 0.28 S -107.5 152.9 56.0 0.28 0.0 HOH
 2.741
 NZ
 O
3euv 2 Q02293 97.65 0.0 X-RAY
 2009-07-07 LYS B:418 B:418 61.0 0.305 S -104.7 158.5 61.0 0.305 0.0 HOH
 4.771
 CE
 O
1n95 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 LYS B:397 B:418 55.0 0.275 S -121.5 147.1 55.0 0.275 0.0
1n9a 2 Q02293 98.26 0.0 X-RAY
 2003-01-07 LYS B:397 B:418 55.0 0.275 S -122.3 148.2 55.0 0.275 0.0
1ni1 2 Q02293 98.26 0.0 X-RAY
 2004-04-06 LYS B:397 B:418 65.0 0.325 S -112.1 173.1 65.0 0.325 0.0
1nl4 2 Q02293 98.25 0.0 X-RAY
 2003-02-11 LYS B:396 B:418 58.0 0.29 S -116.0 153.2 58.0 0.29 0.0
2bed 2 Q02293 98.25 0.0 X-RAY
 2006-08-08 LYS B:396 B:418 63.0 0.315 S -95.7 155.4 63.0 0.315 0.0 HOH
 2.566
 NZ
 O
2r2l 2 Q02293 98.25 0.0 X-RAY
 2008-03-11 LYS B:396 B:418 58.0 0.29 S -90.4 151.4 58.0 0.29 0.0 HOH
 2.816
 NZ
 O
1ft2 2 Q02293 98.25 0.0 X-RAY
 1998-11-04 LYS B:397 B:418 59.0 0.295 S -93.9 148.3 59.0 0.295 0.0
1n94 2 Q02293 98.24 0.0 X-RAY
 2003-01-07 LYS B:397 B:418 167.0 NA -155.7 360.0 167.0 NA NA
1x81 2 Q02293 98.24 0.0 X-RAY
 2004-12-21 LYS B:397 B:418 155.0 NA -142.5 360.0 155.0 NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p49356-f1 1 P49356 100.0 0.0 LYS A:418 A:418 63.0 0.315 S -105.4 134.8