Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67477170 . G A CCDS10222.1:NM_005902.3:c.977tGg>tAg_NP_005893.1:p.326W>* Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 TRP A:128 A:368 105.0 0.412 -75.1 165.9 105.0 0.412 0.0 HOH
 3.580
 CA
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 TRP A:128 A:368 120.0 0.471 -92.0 160.7 120.0 0.471 0.0 TAR
GOL
HOH
 6.846
3.297
3.681
 CH2
CH2
CZ2
 O41
HO3
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 TRP A:107 A:325 93.0 0.365 -71.2 158.0 7.0 0.027 0.338 B:O95405:0.298
A:P84022:0.075
 ACY
ACY
ACY
 5.402
6.369
8.188
 O
O
CD1
 OXT
CH3
OXT
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 TRP A:109 A:368 99.0 0.388 -100.1 160.3 99.0 0.388 0.0 HOH
 2.668
 O
 O
TRP C:109 C:368 98.0 0.384 -87.0 158.2 98.0 0.384 0.0 HOH
 2.861
 O
 O
TRP E:109 E:368 105.0 0.412 -99.6 158.4 105.0 0.412 0.0 HOH
 2.636
 O
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 TRP A:109 A:368 119.0 0.467 -106.1 161.4 119.0 0.467 0.0
TRP C:109 C:368 118.0 0.463 -106.2 161.6 118.0 0.463 0.0
TRP E:109 E:368 124.0 0.486 -104.5 159.7 124.0 0.486 0.0
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 TRP A:99 A:326 108.0 0.424 -118.1 140.8 108.0 0.424 0.0 HOH
 3.722
 CB
 O
TRP C:99 C:326 170.0 0.667 S -78.3 125.7 170.0 0.667 0.0 HOH
 5.940
 O
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 TRP A:109 A:326 115.0 0.451 -82.8 162.7 39.0 0.153 0.298 B:P0AA25+O75593:0.298
 HOH
 5.648
 CE3
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 TRP A:98 NA:NA DO NA DO DO DO NA NA NA
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 TRP A:99 A:368 108.0 0.424 -116.6 144.1 108.0 0.424 0.0
TRP B:99 C:368 110.0 0.431 S -76.8 134.5 110.0 0.431 0.0
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 TRP A:109 NA:NA DO NA DO DO DO NA NA NA
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 TRP A:110 A:368 106.0 0.416 -94.0 168.3 16.0 0.063 0.353 D:Q9Y2U8:0.353
TRP B:110 B:368 118.0 0.463 -94.2 168.3 16.0 0.063 0.4 E:Q9Y2U8:0.4
TRP C:110 C:368 122.0 0.478 -96.8 168.6 122.0 0.478 0.0
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 TRP A:108 A:368 100.0 0.392 -87.9 160.3 26.0 0.102 0.29 B:O95405:0.29
TRP C:108 C:368 103.0 0.404 -89.1 163.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 TRP A:326 A:326 121.0 0.475 -88.2 154.4
af-q15796-f1 1 Q15796 83.73 0.0 TRP A:368 A:368 117.0 0.459 -88.2 157.3