Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67479732 . G A CCDS10222.1:NM_005902.3:c.1039Gag>Aag_NP_005893.1:p.347E>K Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 GLU A:149 A:389 69.0 0.363 H -59.2 -44.4 69.0 0.363 0.0 HOH
 2.559
 OE2
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 GLU A:149 A:389 71.0 0.374 H -65.2 -35.3 71.0 0.374 0.0 HOH
 4.563
 CG
 O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 GLU A:128 A:346 35.0 0.184 H -43.9 -36.2 35.0 0.184 0.0
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 GLU A:130 A:389 64.0 0.337 H -63.6 -40.4 64.0 0.337 0.0 HOH
 2.599
 OE2
 O
GLU C:130 C:389 69.0 0.363 H -62.7 -42.4 69.0 0.363 0.0 HOH
 2.690
 O
 O
GLU E:130 E:389 67.0 0.353 H -66.9 -36.4 67.0 0.353 0.0 HOH
 2.702
 O
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 GLU A:130 A:389 54.0 0.284 H -60.3 -46.4 54.0 0.284 0.0
GLU C:130 C:389 53.0 0.279 H -60.5 -46.3 53.0 0.279 0.0
GLU E:130 E:389 54.0 0.284 H -61.2 -46.1 54.0 0.284 0.0
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 GLU A:120 A:347 57.0 0.3 H -56.4 -50.6 57.0 0.3 0.0 HOH
 7.095
 OE2
 O
GLU C:120 C:347 72.0 0.379 H -55.4 -60.0 72.0 0.379 0.0 HOH
 5.427
 OE2
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 GLU A:130 A:347 50.0 0.263 H -61.5 -41.5 50.0 0.263 0.0 HOH
 5.599
 N
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 GLU A:119 A:346 30.0 0.158 H -65.7 -45.2 30.0 0.158 0.0 HOH
 4.925
 OE2
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 GLU A:120 A:389 56.0 0.295 H -56.0 -49.6 56.0 0.295 0.0
GLU B:120 C:389 67.0 0.353 H -54.1 -55.7 67.0 0.353 0.0
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 GLU A:130 A:389 90.0 0.474 H -69.5 -29.3 90.0 0.474 0.0 HOH
 2.793
 OE2
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 GLU A:131 A:389 68.0 0.358 H -64.3 -43.3 68.0 0.358 0.0
GLU B:131 B:389 67.0 0.353 H -62.1 -40.7 67.0 0.353 0.0
GLU C:131 C:389 54.0 0.284 H -62.6 -43.0 54.0 0.284 0.0
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 GLU A:129 A:389 60.0 0.316 H -66.1 -44.1 60.0 0.316 0.0
GLU C:129 C:389 70.0 0.368 H -71.3 -32.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 GLU A:347 A:347 65.0 0.342 H -63.7 -43.2
af-q15796-f1 1 Q15796 83.73 0.0 GLU A:389 A:389 66.0 0.347 H -64.0 -42.6