Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67482753 . G A CCDS10222.1:NM_005902.3:c.1157aGa>aAa_NP_005893.1:p.386R>K Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 ARG A:188 A:428 35.0 0.156 -60.4 129.5 15.0 0.067 0.089 A:Q15796:0.089
 HOH
 2.830
 NH2
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 ARG A:188 A:428 75.0 0.333 -68.3 130.1 43.0 0.191 0.142 A:Q15796:0.142
 SO4
HOH
 7.252
2.947
 O
NH2
 O3
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 ARG A:167 A:385 80.0 0.356 S -85.8 116.0 80.0 0.356 0.0 ACY
ACY
 6.574
6.688
 O
N
 O
O
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ARG A:169 A:428 33.0 0.147 -74.9 130.2 33.0 0.147 0.0 HOH
 2.876
 NH2
 O
ARG C:169 C:428 45.0 0.2 -75.1 124.1 45.0 0.2 0.0 HOH
 2.847
 NH2
 O
ARG E:169 E:428 42.0 0.187 -65.5 118.1 24.0 0.107 0.08 A:Q15796:0.08
 HOH
 2.898
 NH1
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 ARG A:169 A:428 38.0 0.169 -72.5 119.4 38.0 0.169 0.0
ARG C:169 C:428 43.0 0.191 -72.8 119.1 43.0 0.191 0.0
ARG E:169 E:428 38.0 0.169 -71.8 120.7 38.0 0.169 0.0
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 ARG A:159 A:386 48.0 0.213 -71.9 120.2 27.0 0.12 0.093 C:P84022:0.093
 HOH
 2.946
 NH2
 O
ARG C:159 C:386 76.0 0.338 -110.8 100.7 76.0 0.338 0.0 HOH
 5.663
 NE
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 ARG A:169 A:386 45.0 0.2 -82.9 114.9 45.0 0.2 0.0 HOH
 3.146
 NH2
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 ARG A:158 NA:NA DO NA DO DO DO NA NA NA
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 ARG A:159 A:428 44.0 0.196 -70.4 115.0 23.0 0.102 0.094 B:Q15796:0.093
ARG B:159 C:428 71.0 0.316 -114.6 93.0 71.0 0.316 0.0
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 ARG A:169 A:428 72.0 0.32 -71.4 110.2 72.0 0.32 0.0 HOH
 3.054
 NH2
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 ARG A:170 A:428 38.0 0.169 -75.4 124.8 38.0 0.169 0.0
ARG B:170 B:428 36.0 0.16 -78.0 130.2 36.0 0.16 0.0
ARG C:170 C:428 39.0 0.173 -75.1 123.3 39.0 0.173 0.0
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 ARG A:168 A:428 37.0 0.164 -78.0 135.7 37.0 0.164 0.0
ARG C:168 C:428 149.0 0.662 360.0 118.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 ARG A:386 A:386 87.0 0.387 -92.1 111.5
af-q15796-f1 1 Q15796 83.73 0.0 ARG A:428 A:428 75.0 0.333 -82.9 114.1