Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67482774 . C A CCDS10222.1:NM_005902.3:c.1178cCc>cAc_NP_005893.1:p.393P>H Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 PRO A:195 A:435 1.0 0.007 S -60.4 -45.1 1.0 0.007 0.0 HOH
 3.178
 CD
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 PRO A:195 A:435 1.0 0.007 S -67.6 -34.0 1.0 0.007 0.0 HOH
 3.411
 CD
 O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 PRO A:174 A:392 4.0 0.028 S -47.9 -53.3 4.0 0.028 0.0
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 PRO A:176 A:435 1.0 0.007 S -73.6 -29.4 1.0 0.007 0.0 HOH
 3.087
 CD
 O
PRO C:176 C:435 0.0 0.0 S -72.0 -31.0 0.0 0.0 0.0 HOH
 3.216
 CD
 O
PRO E:176 E:435 0.0 0.0 S -69.7 -33.5 0.0 0.0 0.0 HOH
 3.318
 CD
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 PRO A:176 A:435 2.0 0.014 S -62.9 -47.5 2.0 0.014 0.0
PRO C:176 C:435 1.0 0.007 S -62.9 -47.5 1.0 0.007 0.0
PRO E:176 E:435 1.0 0.007 S -62.8 -46.9 1.0 0.007 0.0
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 PRO A:166 A:393 2.0 0.014 S -64.4 -39.8 2.0 0.014 0.0 HOH
 3.140
 CD
 O
PRO C:166 C:393 5.0 0.034 S -76.9 -35.4 5.0 0.034 0.0 HOH
 2.852
 CD
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 PRO A:176 A:393 4.0 0.028 S -73.0 -29.0 4.0 0.028 0.0 HOH
 3.130
 CD
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 PRO A:165 A:392 8.0 0.055 S -56.5 -46.2 8.0 0.055 0.0 HOH
 3.233
 CD
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 PRO A:166 A:435 0.0 0.0 S -60.0 -49.2 0.0 0.0 0.0
PRO B:166 C:435 4.0 0.028 S -73.5 -39.4 4.0 0.028 0.0
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 PRO A:176 A:435 1.0 0.007 S -70.2 -32.1 1.0 0.007 0.0 HOH
 3.249
 CD
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 PRO A:177 A:435 2.0 0.014 S -69.2 -34.3 2.0 0.014 0.0
PRO B:177 B:435 0.0 0.0 S -69.4 -34.6 0.0 0.0 0.0
PRO C:177 C:435 2.0 0.014 S -68.7 -33.1 2.0 0.014 0.0
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 PRO A:175 A:435 0.0 0.0 S -61.6 -53.5 0.0 0.0 0.0
PRO C:175 C:435 18.0 0.124 S -50.0 -49.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 PRO A:393 A:393 4.0 0.028 S -72.1 -26.1
af-q15796-f1 1 Q15796 83.73 0.0 PRO A:435 A:435 1.0 0.007 S -69.7 -30.2