Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67482813 . G A CCDS10222.1:NM_005902.3:c.1217tGg>tAg_NP_005893.1:p.406W>* Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 TRP A:208 A:448 133.0 0.522 H -60.1 -44.6 133.0 0.522 0.0 HOH
 2.660
 O
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 TRP A:208 A:448 152.0 0.596 H -63.6 -41.4 0.0 0.0 0.596 B:P12755:0.596
 GOL
HOH
 8.204
3.766
 CD1
NE1
 O3
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 TRP A:187 A:405 24.0 0.094 H -50.9 -36.1 0.0 0.0 0.094 B:O95405:0.094
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 TRP A:189 A:448 101.0 0.396 H -59.5 -44.2 17.0 0.067 0.329 B:None:0.329
 HOH
 3.383
 CD1
 O
TRP C:189 C:448 98.0 0.384 H -57.6 -46.9 13.0 0.051 0.333 D:None:0.333
 HOH
 3.361
 NE1
 O
TRP E:189 E:448 101.0 0.396 H -56.2 -46.0 9.0 0.035 0.361 F:None:0.361
 HOH
 3.387
 CD1
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 TRP A:189 A:448 93.0 0.365 H -61.5 -40.1 14.0 0.055 0.31 B:Q92793:0.31
TRP C:189 C:448 85.0 0.333 H -61.3 -41.2 13.0 0.051 0.282 D:Q92793:0.282
TRP E:189 E:448 88.0 0.345 H -61.0 -41.5 15.0 0.059 0.286 F:Q92793:0.286
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 TRP A:179 A:406 85.0 0.333 H -65.5 -38.6 85.0 0.333 0.0 HOH
 2.891
 CH2
 O
TRP C:179 C:406 86.0 0.337 H -65.8 -44.1 86.0 0.337 0.0 HOH
 2.650
 NE1
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 TRP A:189 A:406 4.0 0.016 H -63.3 -45.4 4.0 0.016 0.0
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 TRP A:178 A:405 86.0 0.337 H -64.9 -45.7 86.0 0.337 0.0 HOH
 3.551
 N
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 TRP A:179 A:448 86.0 0.337 H -65.0 -36.8 86.0 0.337 0.0
TRP B:179 C:448 82.0 0.322 H -68.4 -39.3 82.0 0.322 0.0
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 TRP A:189 A:448 160.0 0.627 H -62.4 -41.0 10.0 0.039 0.588 B:P12755:0.588
 HOH
 3.240
 CD1
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 TRP A:190 A:448 56.0 0.22 H -64.3 -42.2 56.0 0.22 0.0
TRP B:190 B:448 85.0 0.333 H -64.5 -42.5 85.0 0.333 0.0
TRP C:190 C:448 88.0 0.345 H -64.8 -42.9 88.0 0.345 0.0
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 TRP A:188 A:448 30.0 0.118 H -63.8 -45.0 2.0 0.008 0.11 B:O95405:0.11
TRP C:188 C:448 25.0 0.098 H -71.2 -44.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 TRP A:406 A:406 2.0 0.008 H -69.5 -41.9
af-q15796-f1 1 Q15796 83.73 0.0 TRP A:448 A:448 3.0 0.012 H -66.9 -42.3