Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 99478569 . C A CCDS10378.1:NM_000875.3:c.3211Caa>Aaa_NP_000866.1:p.1071Q>K Homo sapiens insulin-like growth factor 1 receptor (IGF1R), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6jk8 1 P08069 100.0 0.0 EM
 2020-03-04 GLN A:1071 NA:NA DO NA DO DO DO NA NA NA
GLN B:1071 NA:NA DO NA DO DO DO NA NA NA
6pyh 1 Q60751 95.96 0.0 EM
 2019-10-23 GLN A:1042 NA:NA DO NA DO DO DO NA NA NA
GLN C:1042 NA:NA DO NA DO DO DO NA NA NA
3lvp 1 P08069 100.0 0.0 X-RAY
 2010-07-21 GLN A:121 A:1071 175.0 0.972 S -47.4 108.7 175.0 0.972 0.0
GLN B:121 B:1071 130.0 0.722 S -90.7 64.3 NA NA NA
GLN C:121 C:1071 114.0 0.633 S -128.1 123.4 NA NA NA
GLN D:121 D:1071 155.0 0.861 S -74.9 115.6 NA NA NA
1m7n 1 P08069 100.0 0.0 X-RAY
 2003-01-07 GLN A:99 A:1068 126.0 0.7 S -74.0 128.2 126.0 0.7 0.0 HOH
 4.100
 CG
 O
GLN B:99 B:1068 120.0 0.667 S -106.1 128.3 NA NA NA
1p4o 1 P08069 99.38 0.0 X-RAY
 2003-04-29 GLN A:99 A:1041 107.0 0.594 S -108.5 133.7 107.0 0.594 0.0 HOH
 2.893
 O
 O
GLN B:99 B:1041 115.0 0.639 S -109.7 132.5 NA NA NA
5fxq 1 P08069 100.0 0.0 X-RAY
 2016-10-19 GLN A:93 A:1071 112.0 0.622 S -90.4 116.1 112.0 0.622 0.0 HOH
 2.350
 O
 O
5fxr 1 P08069 100.0 0.0 X-RAY
 2016-10-19 GLN A:93 A:1071 115.0 0.639 S -86.9 116.4 115.0 0.639 0.0 HOH
 2.348
 O
 O
1jqh 1 P08069 100.0 0.0 X-RAY
 2002-04-19 GLN A:93 A:1071 121.0 0.672 S -83.1 106.2 121.0 0.672 0.0 HOH
 6.734
 C
 O
GLN B:93 B:1071 118.0 0.656 S -83.9 106.0 NA NA NA
GLN C:93 C:1071 119.0 0.661 S -84.0 105.5 NA NA NA
2zm3 1 P08069 100.0 0.0 X-RAY
 2008-06-10 GLN A:93 A:1071 118.0 0.656 S -87.4 66.5 118.0 0.656 0.0 HOH
 2.833
 OE1
 O
GLN B:93 B:1071 92.0 0.511 S -98.0 124.6 NA NA NA
GLN C:93 C:1071 136.0 0.756 S -87.4 123.0 NA NA NA
GLN D:93 D:1071 93.0 0.517 S -84.8 123.6 NA NA NA
3f5p 1 P08069 100.0 0.0 X-RAY
 2008-12-30 GLN A:93 A:1071 105.0 0.583 S -90.3 91.8 105.0 0.583 0.0
GLN B:93 B:1071 120.0 0.667 S -94.3 98.7 NA NA NA
GLN C:93 C:1071 133.0 0.739 S -91.0 109.7 NA NA NA
GLN D:93 D:1071 134.0 0.744 S -73.3 129.0 NA NA NA
GLN E:93 E:1071 107.0 0.594 S -78.2 101.2 NA NA NA
GLN F:93 F:1071 137.0 0.761 S -94.0 87.2 NA NA NA
GLN G:93 G:1071 80.0 0.444 S -89.6 100.6 NA NA NA
GLN H:93 H:1071 101.0 0.561 S -68.9 116.1 NA NA NA
GLN I:93 I:1071 78.0 0.433 S -86.9 91.2 NA NA NA
GLN J:93 J:1071 97.0 0.539 S -95.0 93.4 NA NA NA
GLN K:93 K:1071 111.0 0.617 S -87.3 98.5 NA NA NA
GLN L:93 M:1071 105.0 0.583 S -82.0 95.0 NA NA NA
GLN M:93 L:1071 110.0 0.611 S -82.4 104.6 NA NA NA
GLN N:93 R:1071 106.0 0.589 S -87.8 90.5 NA NA NA
GLN O:93 S:1071 111.0 0.617 S -108.8 95.9 NA NA NA
GLN P:93 T:1071 118.0 0.656 S -79.9 83.8 NA NA NA
3i81 1 P08069 99.67 0.0 X-RAY
 2009-12-22 GLN A:92 A:1041 126.0 0.7 S -79.9 115.6 126.0 0.7 0.0 HOH
 3.933
 CB
 O
5fxs 1 P08069 99.35 0.0 X-RAY
 2016-10-19 GLN A:93 A:1071 116.0 0.644 S -92.7 123.0 116.0 0.644 0.0 ACT
HOH
 7.837
2.777
 O
O
 OXT
O
2oj9 1 P08069 100.0 0.0 X-RAY
 2007-05-01 GLN A:92 A:1041 104.0 0.578 S -89.4 101.4 104.0 0.578 0.0 HOH
 3.047
 O
 O
3nw5 1 P08069 100.0 0.0 X-RAY
 2010-07-28 GLN A:92 A:1041 110.0 0.611 S -102.1 118.3 110.0 0.611 0.0 HOH
 2.783
 OE1
 O
3nw6 1 P08069 100.0 0.0 X-RAY
 2010-07-28 GLN A:92 A:1041 119.0 0.661 S -94.5 114.0 119.0 0.661 0.0 HOH
 3.271
 O
 O
3nw7 1 P08069 100.0 0.0 X-RAY
 2010-07-28 GLN A:92 A:1041 120.0 0.667 S -82.8 107.2 120.0 0.667 0.0 HOH
 2.916
 O
 O
3o23 1 P08069 99.67 0.0 X-RAY
 2011-05-04 GLN A:90 A:1071 116.0 0.644 S -133.5 137.1 116.0 0.644 0.0
3lw0 1 P08069 99.34 0.0 X-RAY
 2010-09-29 GLN A:89 A:1071 109.0 0.606 S -101.4 124.4 109.0 0.606 0.0 HOH
 2.579
 OE1
 O
GLN B:89 B:1071 109.0 0.606 S -101.7 122.5 NA NA NA
GLN C:89 C:1071 109.0 0.606 S -103.5 124.7 NA NA NA
GLN D:89 D:1071 108.0 0.6 S -104.1 126.1 NA NA NA
5hzn 1 P08069 99.34 0.0 X-RAY
 2016-04-06 GLN A:89 A:1068 115.0 0.639 S -91.5 121.0 115.0 0.639 0.0 HOH
 4.277
 CB
 O
GLN B:89 B:1068 111.0 0.617 S -106.3 123.7 NA NA NA
GLN C:89 C:1068 121.0 0.672 S -102.6 127.3 NA NA NA
GLN D:89 D:1068 108.0 0.6 S -103.0 121.8 NA NA NA
GLN E:89 E:1068 118.0 0.656 S -91.7 119.7 NA NA NA
GLN F:89 F:1068 111.0 0.617 S -106.0 123.9 NA NA NA
GLN G:89 G:1068 119.0 0.661 S -102.5 127.7 NA NA NA
GLN H:89 H:1068 109.0 0.606 S -101.4 122.4 NA NA NA
4d2r 1 P08069 100.0 0.0 X-RAY
 2015-04-22 GLN A:87 A:1071 116.0 0.644 S -90.5 117.5 116.0 0.644 0.0 HOH
 2.843
 O
 O
3d94 1 P08069 99.67 0.0 X-RAY
 2008-07-29 GLN A:86 A:1041 111.0 0.617 S -103.6 131.2 111.0 0.617 0.0 HOH
 3.022
 CB
 O
3qqu 1 P08069 100.0 0.0 X-RAY
 2011-04-20 GLN A:86 A:1068 140.0 0.778 S -131.5 135.8 140.0 0.778 0.0 HOH
 4.148
 NE2
 O
GLN B:86 B:1068 127.0 0.706 S -120.4 118.0 NA NA NA
GLN C:86 C:1068 62.0 NA S -85.5 133.7 NA NA NA
GLN D:86 D:1068 131.0 0.728 S -86.3 106.2 NA NA NA
1k3a 1 P08069 99.67 0.0 X-RAY
 2001-11-28 GLN A:84 A:1041 147.0 0.817 S -116.7 128.1 147.0 0.817 0.0 HOH
 2.904
 O
 O
2z8c 1 P06213 80.2 1e-175 X-RAY
 2008-08-12 LYS A:88 A:1068 58.0 NA S -56.8 107.2 58.0 NA NA
1gag 1 P06213 80.2 2e-175 X-RAY
 2001-01-17 LYS A:91 A:1068 74.0 NA S -70.7 95.3 74.0 NA NA
1ir3 1 P06213 80.2 2e-175 X-RAY
 1998-01-07 LYS A:91 A:1068 73.0 NA S -77.7 79.9 73.0 NA NA HOH
 3.399
 CB
 O
1irk 1 P06213 80.2 2e-175 X-RAY
 1995-02-27 LYS A:91 A:1068 159.0 0.795 S -99.9 135.4 159.0 0.795 0.0 HOH
 3.320
 O
 O
5e1s 1 P06213 80.2 2e-175 X-RAY
 2015-10-14 LYS A:93 A:1068 137.0 0.685 S -72.0 112.4 137.0 0.685 0.0 HOH
 4.868
 N
 O
1rqq 1 P06213 80.2 3e-175 X-RAY
 2003-12-30 LYS A:91 A:1068 73.0 NA S -59.9 105.7 73.0 NA NA
LYS B:91 B:1068 72.0 NA S -60.3 105.0 72.0 NA NA
2auh 1 P06213 80.2 3e-175 X-RAY
 2005-11-01 LYS A:91 A:1068 64.0 NA S -73.2 81.7 64.0 NA NA
2b4s 2 P06213 80.2 3e-175 X-RAY
 2005-11-15 LYS B:91 B:1068 174.0 0.87 S -77.8 111.4 142.0 0.71 0.16 D:P06213:0.16
 HOH
 3.871
 CB
 O
LYS D:91 D:1068 173.0 0.865 S -81.2 106.9 140.0 0.7 0.165 B:P06213:0.165
 HOH
 2.552
 O
 O
3bu3 1 P06213 80.2 3e-175 X-RAY
 2008-02-19 LYS A:91 A:1068 66.0 NA S -93.1 123.5 66.0 NA NA HOH
 2.794
 O
 O
3bu5 1 P06213 80.2 3e-175 X-RAY
 2008-02-19 LYS A:91 A:1068 68.0 NA S -80.4 124.3 68.0 NA NA HOH
 2.958
 O
 O
3bu6 1 P06213 80.2 3e-175 X-RAY
 2008-02-19 LYS A:91 A:1068 66.0 NA S -95.7 125.2 66.0 NA NA HOH
 2.938
 O
 O
5hhw 1 P06213 80.2 4e-175 X-RAY
 2016-04-13 LYS A:92 A:1095 153.0 0.765 S -82.4 107.6 153.0 0.765 0.0 HOH
 2.716
 O
 O
4ibm 1 P06213 80.73 8e-175 X-RAY
 2013-08-21 LYS A:91 A:1068 152.0 0.76 S -67.2 138.4 152.0 0.76 0.0 HOH
 2.571
 O
 O
LYS B:91 NA:NA DO NA DO DO DO NA NA NA
3eta 1 P06213 80.41 2e-170 X-RAY
 2009-05-26 LYS A:90 A:1068 68.0 NA S -79.7 115.9 68.0 NA NA HOH
 6.382
 N
 O
LYS B:90 B:1068 173.0 0.865 S -63.8 114.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08069-f1 1 P08069 100.0 0.0 GLN A:1071 A:1071 127.0 0.706 S -81.8 135.1