Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr15 | 63631102 | . | C | A | CCDS10185.1:NM_001218.3:c.790Gac>Tac_NP_001209.1:p.264D>Y | Homo sapiens carbonic anhydrase XII (CA12), transcript variant 1, mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1jcz | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2001-08-17 | ASP | A:236 | A:237 | 53.0 | 0.353 | -67.0 | 119.7 | 53.0 | 0.353 | 0.0 |
HOH |
2.791 |
O |
O |
|||
| ASP | B:236 | B:237 | 59.0 | 0.393 | -64.4 | 140.7 | 59.0 | 0.393 | 0.0 |
HOH |
2.692 |
O |
O |
||||||||||
| 1jd0 | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2001-08-17 | ASP | A:236 | A:237 | 60.0 | 0.4 | -99.2 | 117.8 | 60.0 | 0.4 | 0.0 |
HOH |
2.715 |
OD2 |
O |
|||
| ASP | B:236 | B:237 | 57.0 | 0.38 | -64.9 | 141.8 | 57.0 | 0.38 | 0.0 |
HOH |
2.635 |
OD2 |
O |
||||||||||
| 6qn0 | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2020-02-26 | ASP | A:236 | A:237 | 52.0 | 0.347 | -81.7 | 127.8 | 52.0 | 0.347 | 0.0 |
HOH |
2.709 |
O |
O |
|||
| ASP | B:236 | B:237 | 59.0 | 0.393 | -62.1 | 134.4 | 59.0 | 0.393 | 0.0 |
HOH |
3.679 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:237 | 59.0 | 0.393 | -78.3 | 122.9 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:237 | 66.0 | 0.44 | -56.9 | 126.8 | NA | NA | NA | ||||||||||||||
| 6qng | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2020-03-04 | ASP | A:236 | A:237 | 63.0 | 0.42 | -82.0 | 123.4 | 63.0 | 0.42 | 0.0 |
HOH |
2.675 |
OD2 |
O |
|||
| ASP | B:236 | B:237 | 58.0 | 0.387 | -75.5 | 113.0 | 58.0 | 0.387 | 0.0 |
HOH |
2.640 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:237 | 64.0 | 0.427 | -79.8 | 116.8 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:237 | 52.0 | 0.347 | -69.1 | 131.2 | NA | NA | NA | ||||||||||||||
| 6qnl | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2020-03-04 | ASP | A:236 | A:237 | 54.0 | 0.36 | -69.1 | 126.7 | 54.0 | 0.36 | 0.0 |
HOH |
2.607 |
O |
O |
|||
| ASP | B:236 | B:237 | 57.0 | 0.38 | -70.0 | 125.3 | 57.0 | 0.38 | 0.0 |
HOH |
2.526 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:237 | 53.0 | 0.353 | -68.9 | 126.9 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:237 | 59.0 | 0.393 | -70.2 | 123.4 | NA | NA | NA | ||||||||||||||
| 4ht2 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2013-04-10 | ASP | A:236 | A:236 | 63.0 | 0.42 | -50.9 | 122.9 | 63.0 | 0.42 | 0.0 |
HOH |
2.687 |
O |
O |
|||
| ASP | B:236 | B:236 | 60.0 | 0.4 | -75.5 | 131.3 | NA | NA | NA | ||||||||||||||
| ASP | C:236 | C:236 | 59.0 | 0.393 | -72.4 | 133.9 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 55.0 | 0.367 | -83.7 | 129.3 | NA | NA | NA | ||||||||||||||
| 4kp5 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2013-11-06 | ASP | A:236 | A:236 | 52.0 | 0.347 | -62.3 | 118.2 | 52.0 | 0.347 | 0.0 |
HOH |
2.268 |
OD1 |
O |
|||
| ASP | B:236 | B:236 | 55.0 | 0.367 | -80.6 | 124.7 | 55.0 | 0.367 | 0.0 |
HOH |
2.496 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 67.0 | 0.447 | -48.6 | 126.1 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 55.0 | 0.367 | -77.4 | 129.2 | NA | NA | NA | ||||||||||||||
| 4kp8 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2013-11-06 | ASP | A:236 | A:236 | 65.0 | 0.433 | -58.1 | 117.8 | 65.0 | 0.433 | 0.0 |
HOH |
2.834 |
OD2 |
O |
|||
| ASP | B:236 | B:236 | 62.0 | 0.413 | -73.0 | 123.5 | 62.0 | 0.413 | 0.0 |
HOH |
2.715 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 51.0 | 0.34 | -76.4 | 118.2 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 60.0 | 0.4 | -81.9 | 123.9 | NA | NA | NA | ||||||||||||||
| 4q0l | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-01-28 | ASP | A:236 | A:236 | 49.0 | 0.327 | -75.1 | 124.2 | 49.0 | 0.327 | 0.0 |
HOH |
3.630 |
C |
O |
|||
| ASP | B:236 | B:236 | 59.0 | 0.393 | -87.9 | 110.9 | 59.0 | 0.393 | 0.0 |
HOH |
8.267 |
N |
O |
||||||||||
| ASP | C:236 | C:236 | 63.0 | 0.42 | -77.5 | 123.0 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 62.0 | 0.413 | -52.5 | 115.8 | NA | NA | NA | ||||||||||||||
| 4qj0 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-04-15 | ASP | A:236 | A:236 | 48.0 | 0.32 | -57.6 | 119.7 | 48.0 | 0.32 | 0.0 |
HOH |
2.781 |
OD2 |
O |
|||
| ASP | B:236 | B:236 | 55.0 | 0.367 | -78.6 | 128.1 | 55.0 | 0.367 | 0.0 |
HOH |
2.584 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 64.0 | 0.427 | -41.2 | 119.1 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 59.0 | 0.393 | -72.5 | 127.0 | NA | NA | NA | ||||||||||||||
| 4qjo | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-04-15 | ASP | A:236 | A:236 | 54.0 | 0.36 | -77.4 | 121.7 | 54.0 | 0.36 | 0.0 |
HOH |
3.957 |
O |
O |
|||
| ASP | B:236 | B:236 | 56.0 | 0.373 | -71.1 | 128.2 | 56.0 | 0.373 | 0.0 |
HOH |
2.524 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 60.0 | 0.4 | -81.3 | 117.1 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 55.0 | 0.367 | -69.9 | 123.8 | NA | NA | NA | ||||||||||||||
| 4qjw | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-04-15 | ASP | A:236 | A:236 | 65.0 | 0.433 | -61.2 | 125.7 | 65.0 | 0.433 | 0.0 |
HOH |
2.811 |
OD2 |
O |
|||
| ASP | B:236 | B:236 | 57.0 | 0.38 | -68.5 | 126.2 | 57.0 | 0.38 | 0.0 |
HOH |
2.535 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 57.0 | 0.38 | -89.4 | 121.7 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 54.0 | 0.36 | -73.9 | 123.3 | NA | NA | NA | ||||||||||||||
| 4ww8 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | ASP | A:236 | A:236 | 59.0 | 0.393 | -70.9 | 120.6 | 59.0 | 0.393 | 0.0 |
HOH |
2.461 |
OD2 |
O |
|||
| ASP | B:236 | B:236 | 59.0 | 0.393 | -72.4 | 126.4 | 59.0 | 0.393 | 0.0 |
HOH |
2.536 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 62.0 | 0.413 | -65.3 | 114.8 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 58.0 | 0.387 | -66.4 | 125.9 | NA | NA | NA | ||||||||||||||
| 5ll5 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | ASP | A:236 | A:236 | 52.0 | 0.347 | -69.7 | 119.5 | 52.0 | 0.347 | 0.0 |
HOH |
2.531 |
O |
O |
|||
| ASP | B:236 | B:236 | 58.0 | 0.387 | -75.8 | 127.8 | 58.0 | 0.387 | 0.0 |
HOH |
2.578 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 65.0 | 0.433 | -52.5 | 115.2 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 57.0 | 0.38 | -73.3 | 128.2 | NA | NA | NA | ||||||||||||||
| 5ll9 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | ASP | A:236 | A:236 | 49.0 | 0.327 | -70.2 | 115.4 | 49.0 | 0.327 | 0.0 |
HOH |
2.635 |
O |
O |
|||
| ASP | B:236 | B:236 | 56.0 | 0.373 | -79.4 | 129.3 | 56.0 | 0.373 | 0.0 |
HOH |
2.520 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 67.0 | 0.447 | -44.8 | 111.7 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 57.0 | 0.38 | -68.9 | 128.8 | NA | NA | NA | ||||||||||||||
| 5llo | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | ASP | A:236 | A:236 | 57.0 | 0.38 | -65.8 | 120.7 | 57.0 | 0.38 | 0.0 |
HOH |
2.377 |
O |
O |
|||
| ASP | B:236 | B:236 | 56.0 | 0.373 | -78.9 | 130.3 | 56.0 | 0.373 | 0.0 |
HOH |
2.552 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 62.0 | 0.413 | -49.7 | 121.6 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 54.0 | 0.36 | -69.8 | 126.8 | NA | NA | NA | ||||||||||||||
| 5llp | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | ASP | A:236 | A:236 | 57.0 | 0.38 | -70.6 | 121.5 | 57.0 | 0.38 | 0.0 |
HOH |
2.599 |
OD2 |
O |
|||
| ASP | B:236 | B:236 | 54.0 | 0.36 | -80.6 | 128.0 | 54.0 | 0.36 | 0.0 |
HOH |
2.365 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 64.0 | 0.427 | -57.4 | 122.6 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 56.0 | 0.373 | -68.9 | 133.0 | NA | NA | NA | ||||||||||||||
| 5msa | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | ASP | A:236 | A:236 | 57.0 | 0.38 | -66.0 | 123.0 | 57.0 | 0.38 | 0.0 |
HOH |
2.559 |
OD2 |
O |
|||
| ASP | B:236 | B:236 | 54.0 | 0.36 | -66.4 | 129.6 | 54.0 | 0.36 | 0.0 |
HOH |
2.501 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 66.0 | 0.44 | -64.9 | 127.7 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 56.0 | 0.373 | -80.4 | 127.4 | NA | NA | NA | ||||||||||||||
| 5msb | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | ASP | A:236 | A:236 | 55.0 | 0.367 | -60.7 | 122.3 | 55.0 | 0.367 | 0.0 |
HOH |
2.546 |
OD1 |
O |
|||
| ASP | B:236 | B:236 | 54.0 | 0.36 | -68.6 | 126.9 | 54.0 | 0.36 | 0.0 |
HOH |
2.376 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 63.0 | 0.42 | -55.5 | 122.0 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 54.0 | 0.36 | -63.1 | 126.5 | NA | NA | NA | ||||||||||||||
| 6g5l | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2019-03-13 | ASP | A:236 | A:236 | 59.0 | 0.393 | -65.7 | 128.3 | 59.0 | 0.393 | 0.0 |
HOH |
2.667 |
OD2 |
O |
|||
| ASP | B:236 | B:236 | 59.0 | 0.393 | -71.9 | 127.7 | 59.0 | 0.393 | 0.0 |
HOH |
2.270 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 65.0 | 0.433 | -51.6 | 118.1 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 58.0 | 0.387 | -68.6 | 126.8 | NA | NA | NA | ||||||||||||||
| 6g7a | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2019-03-13 | ASP | A:236 | A:236 | 56.0 | 0.373 | -64.8 | 119.9 | 56.0 | 0.373 | 0.0 |
HOH |
2.535 |
OD1 |
O |
|||
| ASP | B:236 | B:236 | 58.0 | 0.387 | -79.6 | 128.2 | 58.0 | 0.387 | 0.0 |
HOH |
2.530 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 70.0 | 0.467 | -86.0 | 120.2 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 56.0 | 0.373 | -67.6 | 126.6 | NA | NA | NA | ||||||||||||||
| 6r6y | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | ASP | A:236 | A:236 | 54.0 | 0.36 | -64.6 | 124.6 | 54.0 | 0.36 | 0.0 |
HOH |
2.528 |
OD2 |
O |
|||
| ASP | B:236 | B:236 | 59.0 | 0.393 | -76.4 | 126.0 | 59.0 | 0.393 | 0.0 |
HOH |
2.452 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 57.0 | 0.38 | -70.1 | 121.1 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 57.0 | 0.38 | -72.0 | 124.4 | NA | NA | NA | ||||||||||||||
| 6r71 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | ASP | A:236 | A:236 | 56.0 | 0.373 | -65.6 | 131.2 | 56.0 | 0.373 | 0.0 |
HOH |
2.692 |
OD2 |
O |
|||
| ASP | B:236 | B:236 | 47.0 | 0.313 | -71.7 | 127.6 | 47.0 | 0.313 | 0.0 |
HOH |
2.702 |
OD2 |
O |
||||||||||
| 6t5p | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-10-14 | ASP | A:236 | A:236 | 52.0 | 0.347 | -79.0 | 124.9 | 52.0 | 0.347 | 0.0 |
HOH |
2.841 |
OD2 |
O |
|||
| ASP | B:236 | B:236 | 59.0 | 0.393 | -78.7 | 126.4 | 59.0 | 0.393 | 0.0 |
HOH |
2.466 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 64.0 | 0.427 | -89.9 | 122.3 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 59.0 | 0.393 | -72.0 | 126.4 | NA | NA | NA | ||||||||||||||
| 6t5q | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-10-14 | ASP | A:236 | A:236 | 61.0 | 0.407 | -73.4 | 125.0 | 61.0 | 0.407 | 0.0 | |||||||
| ASP | B:236 | B:236 | 45.0 | 0.3 | -63.2 | 131.6 | 45.0 | 0.3 | 0.0 |
HOH |
2.586 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 58.0 | 0.387 | -52.0 | 132.4 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 63.0 | 0.42 | -76.0 | 133.3 | NA | NA | NA | ||||||||||||||
| 7puu | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | ASP | A:236 | A:236 | 56.0 | 0.373 | -79.1 | 123.4 | 56.0 | 0.373 | 0.0 |
HOH |
2.607 |
OD2 |
O |
|||
| ASP | B:236 | B:236 | 57.0 | 0.38 | -75.2 | 125.3 | 57.0 | 0.38 | 0.0 |
HOH |
2.424 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 63.0 | 0.42 | -67.6 | 126.8 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 56.0 | 0.373 | -75.0 | 125.8 | NA | NA | NA | ||||||||||||||
| 7puv | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | ASP | A:236 | A:236 | 58.0 | 0.387 | -66.5 | 120.4 | 58.0 | 0.387 | 0.0 |
HOH |
2.710 |
OD2 |
O |
|||
| ASP | B:236 | B:236 | 55.0 | 0.367 | -74.7 | 128.1 | 55.0 | 0.367 | 0.0 |
HOH |
2.438 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 62.0 | 0.413 | -69.6 | 125.6 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 59.0 | 0.393 | -68.0 | 127.0 | NA | NA | NA | ||||||||||||||
| 7puw | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | ASP | A:236 | A:236 | 56.0 | 0.373 | -70.6 | 122.9 | 56.0 | 0.373 | 0.0 |
HOH |
2.580 |
OD2 |
O |
|||
| ASP | B:236 | B:236 | 58.0 | 0.387 | -72.5 | 124.3 | 58.0 | 0.387 | 0.0 |
HOH |
2.519 |
OD2 |
O |
||||||||||
| ASP | C:236 | C:236 | 64.0 | 0.427 | -77.9 | 125.0 | NA | NA | NA | ||||||||||||||
| ASP | D:236 | D:236 | 56.0 | 0.373 | -69.8 | 129.6 | NA | NA | NA | ||||||||||||||
| 6rps | 1 | O43570 | 96.7 | 0.0 |
X-RAY |
2019-11-13 | ASP | A:235 | A:237 | 55.0 | 0.367 | -60.2 | 131.7 | 55.0 | 0.367 | 0.0 | |||||||
| ASP | B:235 | B:237 | 62.0 | 0.413 | -57.4 | 132.4 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o43570-f1 | 1 | O43570 | 100.0 | 0.0 | ASP | A:264 | A:264 | 60.0 | 0.4 | -69.9 | 120.3 | ||