Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr15 | 63631107 | . | A | C | CCDS10185.1:NM_001218.3:c.785aTg>aGg_NP_001209.1:p.262M>R | Homo sapiens carbonic anhydrase XII (CA12), transcript variant 1, mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1jcz | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2001-08-17 | MET | A:234 | A:235 | 113.0 | 0.611 | T | -58.4 | -38.3 | 113.0 | 0.611 | 0.0 |
HOH |
2.762 |
O |
O |
||
| MET | B:234 | B:235 | 101.0 | 0.546 | T | -54.9 | 136.7 | 101.0 | 0.546 | 0.0 |
HOH |
2.612 |
O |
O |
|||||||||
| 1jd0 | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2001-08-17 | MET | A:234 | A:235 | 115.0 | 0.622 | T | -62.7 | -36.9 | 115.0 | 0.622 | 0.0 |
HOH |
2.931 |
N |
O |
||
| MET | B:234 | B:235 | 110.0 | 0.595 | T | -54.5 | 135.6 | 110.0 | 0.595 | 0.0 |
HOH |
2.828 |
N |
O |
|||||||||
| 6qn0 | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2020-02-26 | MET | A:234 | A:235 | 119.0 | 0.643 | T | -52.2 | -30.4 | 119.0 | 0.643 | 0.0 |
HOH |
2.633 |
O |
O |
||
| MET | B:234 | B:235 | 116.0 | 0.627 | T | -47.2 | -31.6 | 116.0 | 0.627 | 0.0 |
HOH |
2.885 |
N |
O |
|||||||||
| MET | C:234 | C:235 | 118.0 | 0.638 | T | -48.7 | -31.4 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:235 | 118.0 | 0.638 | T | -53.2 | -38.0 | NA | NA | NA | |||||||||||||
| 6qng | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2020-03-04 | MET | A:234 | A:235 | 132.0 | 0.714 | T | -54.6 | -33.1 | 132.0 | 0.714 | 0.0 |
HOH |
2.742 |
N |
O |
||
| MET | B:234 | B:235 | 121.0 | 0.654 | T | -61.7 | -31.5 | 121.0 | 0.654 | 0.0 |
HOH |
2.729 |
N |
O |
|||||||||
| MET | C:234 | C:235 | 109.0 | 0.589 | T | -57.4 | -31.7 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:235 | 128.0 | 0.692 | T | -57.3 | -17.4 | NA | NA | NA | |||||||||||||
| 6qnl | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2020-03-04 | MET | A:234 | A:235 | 120.0 | 0.649 | T | -52.0 | -38.7 | 120.0 | 0.649 | 0.0 |
HOH |
2.873 |
N |
O |
||
| MET | B:234 | B:235 | 131.0 | 0.708 | T | -55.8 | -33.1 | 131.0 | 0.708 | 0.0 |
HOH |
2.888 |
N |
O |
|||||||||
| MET | C:234 | C:235 | 126.0 | 0.681 | T | -52.3 | -35.3 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:235 | 119.0 | 0.643 | T | -48.2 | -34.4 | NA | NA | NA | |||||||||||||
| 4ht2 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2013-04-10 | MET | A:234 | A:234 | 97.0 | 0.524 | T | -54.3 | 136.2 | 97.0 | 0.524 | 0.0 |
HOH |
2.896 |
N |
O |
||
| MET | B:234 | B:234 | 109.0 | 0.589 | T | -59.1 | 140.8 | NA | NA | NA | |||||||||||||
| MET | C:234 | C:234 | 120.0 | 0.649 | T | -50.7 | -19.8 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 139.0 | 0.751 | T | -70.2 | -13.5 | NA | NA | NA | |||||||||||||
| 4kp5 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2013-11-06 | MET | A:234 | A:234 | 121.0 | 0.654 | T | -50.1 | -40.5 | 121.0 | 0.654 | 0.0 |
HOH |
2.886 |
N |
O |
||
| MET | B:234 | B:234 | 135.0 | 0.73 | T | -45.0 | -47.0 | 135.0 | 0.73 | 0.0 |
HOH |
2.751 |
O |
O |
|||||||||
| MET | C:234 | C:234 | 86.0 | 0.465 | T | -51.1 | -29.4 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 130.0 | 0.703 | T | -53.0 | -42.8 | NA | NA | NA | |||||||||||||
| 4kp8 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2013-11-06 | MET | A:234 | A:234 | 116.0 | 0.627 | T | -61.8 | -31.8 | 116.0 | 0.627 | 0.0 |
HOH |
3.069 |
N |
O |
||
| MET | B:234 | B:234 | 117.0 | 0.632 | T | -58.5 | -16.4 | 117.0 | 0.632 | 0.0 |
HOH |
2.934 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 128.0 | 0.692 | T | -51.5 | -29.3 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 140.0 | 0.757 | T | -54.0 | -14.6 | NA | NA | NA | |||||||||||||
| 4q0l | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-01-28 | MET | A:234 | A:234 | 133.0 | 0.719 | T | -49.9 | -35.5 | 133.0 | 0.719 | 0.0 |
HOH |
3.345 |
CB |
O |
||
| MET | B:234 | B:234 | 129.0 | 0.697 | T | -57.8 | -35.9 | 129.0 | 0.697 | 0.0 |
HOH |
4.834 |
SD |
O |
|||||||||
| MET | C:234 | C:234 | 143.0 | 0.773 | T | -56.2 | -40.2 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 134.0 | 0.724 | T | -54.2 | -37.1 | NA | NA | NA | |||||||||||||
| 4qj0 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-04-15 | MET | A:234 | A:234 | 130.0 | 0.703 | T | -61.6 | -36.1 | 130.0 | 0.703 | 0.0 |
HOH |
3.122 |
N |
O |
||
| MET | B:234 | B:234 | 134.0 | 0.724 | T | -50.0 | -34.1 | 134.0 | 0.724 | 0.0 |
HOH |
2.965 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 100.0 | 0.541 | T | -46.9 | -36.4 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 136.0 | 0.735 | T | -57.2 | -22.7 | NA | NA | NA | |||||||||||||
| 4qjo | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-04-15 | MET | A:234 | A:234 | 123.0 | 0.665 | T | -53.2 | -40.2 | 123.0 | 0.665 | 0.0 |
HOH |
3.165 |
N |
O |
||
| MET | B:234 | B:234 | 141.0 | 0.762 | T | -54.0 | -21.2 | 141.0 | 0.762 | 0.0 |
HOH |
3.922 |
SD |
O |
|||||||||
| MET | C:234 | C:234 | 131.0 | 0.708 | T | -59.0 | -30.4 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 137.0 | 0.741 | T | -59.0 | -23.5 | NA | NA | NA | |||||||||||||
| 4qjw | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-04-15 | MET | A:234 | A:234 | 134.0 | 0.724 | T | -55.3 | -35.5 | 134.0 | 0.724 | 0.0 |
HOH |
4.495 |
N |
O |
||
| MET | B:234 | B:234 | 108.0 | 0.584 | T | -70.4 | 140.1 | 108.0 | 0.584 | 0.0 |
HOH |
3.840 |
O |
O |
|||||||||
| MET | C:234 | C:234 | 120.0 | 0.649 | T | -55.8 | -34.2 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 136.0 | 0.735 | T | -56.7 | -15.5 | NA | NA | NA | |||||||||||||
| 4ww8 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | MET | A:234 | A:234 | 120.0 | 0.649 | T | -49.4 | -37.0 | 120.0 | 0.649 | 0.0 |
HOH |
2.886 |
N |
O |
||
| MET | B:234 | B:234 | 134.0 | 0.724 | T | -53.6 | -36.4 | 134.0 | 0.724 | 0.0 |
HOH |
2.814 |
O |
O |
|||||||||
| MET | C:234 | C:234 | 122.0 | 0.659 | T | -47.1 | -47.0 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 130.0 | 0.703 | T | -53.5 | -36.2 | NA | NA | NA | |||||||||||||
| 5ll5 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | MET | A:234 | A:234 | 124.0 | 0.67 | T | -52.5 | -37.3 | 124.0 | 0.67 | 0.0 |
HOH |
2.872 |
N |
O |
||
| MET | B:234 | B:234 | 135.0 | 0.73 | T | -52.4 | -35.2 | 135.0 | 0.73 | 0.0 |
HOH |
2.876 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 117.0 | 0.632 | T | -50.1 | -48.1 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 136.0 | 0.735 | T | -47.7 | -36.9 | NA | NA | NA | |||||||||||||
| 5ll9 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | MET | A:234 | A:234 | 124.0 | 0.67 | T | -50.5 | -37.5 | 124.0 | 0.67 | 0.0 |
HOH |
2.886 |
N |
O |
||
| MET | B:234 | B:234 | 134.0 | 0.724 | T | -56.5 | -30.2 | 134.0 | 0.724 | 0.0 |
HOH |
2.880 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 126.0 | 0.681 | T | -47.4 | -42.2 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 131.0 | 0.708 | T | -53.6 | -35.1 | NA | NA | NA | |||||||||||||
| 5llo | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | MET | A:234 | A:234 | 125.0 | 0.676 | T | -49.9 | -39.8 | 125.0 | 0.676 | 0.0 |
HOH |
2.715 |
CE |
O |
||
| MET | B:234 | B:234 | 134.0 | 0.724 | T | -51.3 | -34.7 | 134.0 | 0.724 | 0.0 |
HOH |
2.881 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 102.0 | 0.551 | T | -36.9 | -44.8 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 134.0 | 0.724 | T | -51.1 | -34.1 | NA | NA | NA | |||||||||||||
| 5llp | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | MET | A:234 | A:234 | 125.0 | 0.676 | T | -49.8 | -40.8 | 125.0 | 0.676 | 0.0 |
HOH |
2.979 |
N |
O |
||
| MET | B:234 | B:234 | 132.0 | 0.714 | T | -50.4 | -33.9 | 132.0 | 0.714 | 0.0 |
HOH |
2.703 |
O |
O |
|||||||||
| MET | C:234 | C:234 | 107.0 | 0.578 | T | -43.0 | -36.2 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 133.0 | 0.719 | T | -50.6 | -36.0 | NA | NA | NA | |||||||||||||
| 5msa | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | MET | A:234 | A:234 | 126.0 | 0.681 | T | -54.1 | -37.8 | 126.0 | 0.681 | 0.0 |
HOH |
2.879 |
O |
O |
||
| MET | B:234 | B:234 | 136.0 | 0.735 | T | -64.2 | -25.8 | 136.0 | 0.735 | 0.0 |
HOH |
3.312 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 116.0 | 0.627 | T | -38.4 | -37.3 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 132.0 | 0.714 | T | -52.7 | -36.7 | NA | NA | NA | |||||||||||||
| 5msb | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | MET | A:234 | A:234 | 126.0 | 0.681 | T | -52.4 | -37.1 | 126.0 | 0.681 | 0.0 |
HOH |
2.902 |
N |
O |
||
| MET | B:234 | B:234 | 135.0 | 0.73 | T | -44.7 | -47.7 | 135.0 | 0.73 | 0.0 |
HOH |
2.604 |
O |
O |
|||||||||
| MET | C:234 | C:234 | 119.0 | 0.643 | T | -37.5 | -39.2 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 129.0 | 0.697 | T | -52.9 | -34.2 | NA | NA | NA | |||||||||||||
| 6g5l | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2019-03-13 | MET | A:234 | A:234 | 120.0 | 0.649 | T | -55.0 | -38.2 | 120.0 | 0.649 | 0.0 |
HOH |
2.815 |
N |
O |
||
| MET | B:234 | B:234 | 132.0 | 0.714 | T | -56.1 | -33.8 | 132.0 | 0.714 | 0.0 |
HOH |
2.843 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 122.0 | 0.659 | T | -52.1 | -34.5 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 132.0 | 0.714 | T | -56.8 | -36.5 | NA | NA | NA | |||||||||||||
| 6g7a | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2019-03-13 | MET | A:234 | A:234 | 127.0 | 0.686 | T | -46.8 | -41.0 | 127.0 | 0.686 | 0.0 |
HOH |
2.942 |
N |
O |
||
| MET | B:234 | B:234 | 133.0 | 0.719 | T | -51.8 | -35.0 | 133.0 | 0.719 | 0.0 |
HOH |
2.861 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 128.0 | 0.692 | T | -54.7 | -34.8 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 130.0 | 0.703 | T | -53.2 | -37.3 | NA | NA | NA | |||||||||||||
| 6r6y | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | MET | A:234 | A:234 | 125.0 | 0.676 | T | -51.6 | -38.4 | 125.0 | 0.676 | 0.0 |
HOH |
2.864 |
N |
O |
||
| MET | B:234 | B:234 | 136.0 | 0.735 | T | -59.4 | -25.7 | 136.0 | 0.735 | 0.0 |
HOH |
2.846 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 120.0 | 0.649 | T | -54.4 | -38.2 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 133.0 | 0.719 | T | -55.8 | -32.9 | NA | NA | NA | |||||||||||||
| 6r71 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | MET | A:234 | A:234 | 125.0 | 0.676 | T | -63.2 | -31.4 | 125.0 | 0.676 | 0.0 |
HOH |
3.099 |
N |
O |
||
| MET | B:234 | B:234 | 124.0 | 0.67 | T | -56.0 | -37.4 | 124.0 | 0.67 | 0.0 |
HOH |
3.134 |
N |
O |
|||||||||
| 6t5p | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-10-14 | MET | A:234 | A:234 | 128.0 | 0.692 | T | -58.8 | -36.6 | 128.0 | 0.692 | 0.0 |
HOH |
3.123 |
N |
O |
||
| MET | B:234 | B:234 | 135.0 | 0.73 | T | -54.5 | -32.2 | 135.0 | 0.73 | 0.0 |
HOH |
2.949 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 119.0 | 0.643 | T | -45.9 | -39.4 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 133.0 | 0.719 | T | -55.2 | -28.2 | NA | NA | NA | |||||||||||||
| 6t5q | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-10-14 | MET | A:234 | A:234 | 130.0 | 0.703 | T | -48.3 | -38.4 | 130.0 | 0.703 | 0.0 |
HOH |
6.318 |
SD |
O |
||
| MET | B:234 | B:234 | 111.0 | 0.6 | T | -54.2 | -32.7 | 111.0 | 0.6 | 0.0 |
HOH |
2.905 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 128.0 | 0.692 | T | -51.1 | -38.7 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 134.0 | 0.724 | T | -62.9 | -29.1 | NA | NA | NA | |||||||||||||
| 7puu | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | MET | A:234 | A:234 | 126.0 | 0.681 | T | -51.1 | -38.9 | 126.0 | 0.681 | 0.0 |
HOH |
2.887 |
N |
O |
||
| MET | B:234 | B:234 | 135.0 | 0.73 | T | -52.1 | -33.7 | 135.0 | 0.73 | 0.0 |
HOH |
2.866 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 103.0 | 0.557 | T | -53.6 | -34.3 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 132.0 | 0.714 | T | -55.7 | -34.5 | NA | NA | NA | |||||||||||||
| 7puv | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | MET | A:234 | A:234 | 117.0 | 0.632 | T | -45.9 | -37.6 | 117.0 | 0.632 | 0.0 |
HOH |
3.864 |
CE |
O |
||
| MET | B:234 | B:234 | 134.0 | 0.724 | T | -53.1 | -35.6 | 134.0 | 0.724 | 0.0 |
HOH |
2.856 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 110.0 | 0.595 | T | -49.9 | -36.9 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 131.0 | 0.708 | T | -51.2 | -40.8 | NA | NA | NA | |||||||||||||
| 7puw | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | MET | A:234 | A:234 | 120.0 | 0.649 | T | -50.9 | -38.5 | 120.0 | 0.649 | 0.0 |
HOH |
2.935 |
N |
O |
||
| MET | B:234 | B:234 | 135.0 | 0.73 | T | -56.1 | -28.8 | 135.0 | 0.73 | 0.0 |
HOH |
3.428 |
N |
O |
|||||||||
| MET | C:234 | C:234 | 106.0 | 0.573 | T | -51.2 | -37.4 | NA | NA | NA | |||||||||||||
| MET | D:234 | D:234 | 132.0 | 0.714 | T | -54.2 | -34.8 | NA | NA | NA | |||||||||||||
| 6rps | 1 | O43570 | 96.7 | 0.0 |
X-RAY |
2019-11-13 | MET | A:233 | A:235 | 127.0 | 0.686 | T | -56.9 | -30.5 | 102.0 | 0.551 | 0.135 |
E:None:0.135 |
|||||
| MET | B:233 | B:235 | 104.0 | 0.562 | T | -54.2 | -36.1 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o43570-f1 | 1 | O43570 | 100.0 | 0.0 | MET | A:262 | A:262 | 131.0 | 0.708 | T | -62.9 | -28.2 | |