Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr15 | 63632931 | . | C | A | CCDS10185.1:NM_001218.3:c.577Gta>Tta_NP_001209.1:p.193V>L | Homo sapiens carbonic anhydrase XII (CA12), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1jcz | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2001-08-17 | VAL | A:165 | A:167 | 0.0 | 0.0 | S | -136.9 | 35.3 | 0.0 | 0.0 | 0.0 |
HOH |
3.406 |
N |
O |
||
VAL | B:165 | B:167 | 0.0 | 0.0 | G | -127.0 | 38.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.027 |
N |
O |
|||||||||
1jd0 | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2001-08-17 | VAL | A:165 | A:167 | 0.0 | 0.0 | S | -136.2 | 34.9 | 0.0 | 0.0 | 0.0 |
HOH |
3.525 |
N |
O |
||
VAL | B:165 | B:167 | 0.0 | 0.0 | G | -128.1 | 35.0 | 0.0 | 0.0 | 0.0 |
HOH |
6.667 |
CG1 |
O |
|||||||||
6qn0 | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2020-02-26 | VAL | A:165 | A:167 | 0.0 | 0.0 | -131.0 | 43.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.465 |
N |
O |
|||
VAL | B:165 | B:167 | 0.0 | 0.0 | G | -129.0 | 32.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.736 |
CG1 |
O |
|||||||||
VAL | C:165 | C:167 | 0.0 | 0.0 | S | -135.3 | 37.2 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:167 | 0.0 | 0.0 | S | -125.6 | 28.2 | NA | NA | NA | |||||||||||||
6qng | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2020-03-04 | VAL | A:165 | A:167 | 0.0 | 0.0 | S | -132.2 | 42.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.736 |
N |
O |
||
VAL | B:165 | B:167 | 0.0 | 0.0 | S | -136.5 | 41.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.354 |
N |
O |
|||||||||
VAL | C:165 | C:167 | 0.0 | 0.0 | G | -130.9 | 44.2 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:167 | 0.0 | 0.0 | S | -132.1 | 34.6 | NA | NA | NA | |||||||||||||
6qnl | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2020-03-04 | VAL | A:165 | A:167 | 0.0 | 0.0 | G | -124.5 | 37.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.890 |
N |
O |
||
VAL | B:165 | B:167 | 0.0 | 0.0 | S | -131.0 | 37.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.637 |
N |
O |
|||||||||
VAL | C:165 | C:167 | 0.0 | 0.0 | S | -129.6 | 34.5 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:167 | 0.0 | 0.0 | S | -129.7 | 40.5 | NA | NA | NA | |||||||||||||
4ht2 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2013-04-10 | VAL | A:165 | A:165 | 0.0 | 0.0 | S | -130.8 | 42.4 | 0.0 | 0.0 | 0.0 |
HOH |
3.484 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -128.2 | 41.0 | NA | NA | NA | |||||||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -134.0 | 38.5 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | S | -132.7 | 39.9 | NA | NA | NA | |||||||||||||
4kp5 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2013-11-06 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -128.0 | 33.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.909 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -134.0 | 34.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.607 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -123.9 | 41.7 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | G | -128.8 | 35.5 | NA | NA | NA | |||||||||||||
4kp8 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2013-11-06 | VAL | A:165 | A:165 | 0.0 | 0.0 | S | -126.6 | 48.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.543 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -129.3 | 34.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.013 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -126.1 | 43.1 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | S | -130.3 | 37.4 | NA | NA | NA | |||||||||||||
4q0l | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-01-28 | VAL | A:165 | A:165 | 0.0 | 0.0 | -130.8 | 47.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.157 |
N |
O |
|||
VAL | B:165 | B:165 | 0.0 | 0.0 | G | -116.2 | 32.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.463 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | G | -133.8 | 44.1 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | G | -122.5 | 37.8 | NA | NA | NA | |||||||||||||
4qj0 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-04-15 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -118.4 | 32.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.121 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -133.3 | 38.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.507 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 1.0 | 0.006 | S | -123.9 | 45.3 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | -130.0 | 39.2 | NA | NA | NA | ||||||||||||||
4qjo | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-04-15 | VAL | A:165 | A:165 | 0.0 | 0.0 | -137.3 | 25.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.533 |
N |
O |
|||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -131.9 | 38.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.107 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -122.9 | 37.6 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | S | -129.5 | 37.8 | NA | NA | NA | |||||||||||||
4qjw | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-04-15 | VAL | A:165 | A:165 | 0.0 | 0.0 | S | -130.9 | 42.1 | 0.0 | 0.0 | 0.0 |
HOH |
3.487 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -131.1 | 40.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.917 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -134.4 | 42.0 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | S | -128.6 | 36.8 | NA | NA | NA | |||||||||||||
4ww8 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -126.6 | 42.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.889 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -131.8 | 37.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.608 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -128.9 | 44.3 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | S | -130.3 | 38.7 | NA | NA | NA | |||||||||||||
5ll5 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -122.8 | 37.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.972 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -130.1 | 38.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.549 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -126.4 | 41.4 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | -131.7 | 37.6 | NA | NA | NA | ||||||||||||||
5ll9 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -121.9 | 36.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.038 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -131.3 | 37.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.509 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -127.7 | 39.1 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | -131.3 | 38.9 | NA | NA | NA | ||||||||||||||
5llo | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -122.9 | 32.8 | 0.0 | 0.0 | 0.0 |
HOH |
3.988 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -133.1 | 41.9 | 0.0 | 0.0 | 0.0 |
HOH |
3.672 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | G | -128.7 | 41.4 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | G | -130.0 | 40.7 | NA | NA | NA | |||||||||||||
5llp | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -126.7 | 36.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.056 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -131.2 | 40.3 | 0.0 | 0.0 | 0.0 |
HOH |
3.613 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -128.3 | 42.2 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | G | -128.2 | 33.5 | NA | NA | NA | |||||||||||||
5msa | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | VAL | A:165 | A:165 | 0.0 | 0.0 | -128.1 | 39.3 | 0.0 | 0.0 | 0.0 |
EDO HOH |
8.762 3.707 |
CG1 N |
O2 O |
|||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -133.1 | 33.1 | 0.0 | 0.0 | 0.0 |
HOH |
3.553 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | G | -130.8 | 43.1 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | G | -128.9 | 39.4 | NA | NA | NA | |||||||||||||
5msb | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | VAL | A:165 | A:165 | 0.0 | 0.0 | -125.2 | 34.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.744 |
N |
O |
|||
VAL | B:165 | B:165 | 0.0 | 0.0 | G | -126.6 | 38.3 | 0.0 | 0.0 | 0.0 |
HOH |
3.764 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | G | -127.6 | 26.5 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | G | -126.7 | 35.4 | NA | NA | NA | |||||||||||||
6g5l | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2019-03-13 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -125.9 | 38.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.800 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -131.5 | 35.9 | 0.0 | 0.0 | 0.0 |
HOH |
3.553 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -126.5 | 40.7 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | G | -130.2 | 39.2 | NA | NA | NA | |||||||||||||
6g7a | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2019-03-13 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -124.0 | 38.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.946 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -128.6 | 35.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.565 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -122.8 | 36.0 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | S | -128.6 | 37.1 | NA | NA | NA | |||||||||||||
6r6y | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -124.8 | 40.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.893 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -131.8 | 38.9 | 0.0 | 0.0 | 0.0 |
HOH |
3.531 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -129.8 | 39.9 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | S | -131.5 | 40.8 | NA | NA | NA | |||||||||||||
6r71 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | VAL | A:165 | A:165 | 0.0 | 0.0 | -133.7 | 36.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.669 |
N |
O |
|||
VAL | B:165 | B:165 | 0.0 | 0.0 | -138.2 | 43.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.395 |
N |
O |
||||||||||
6t5p | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-10-14 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -120.6 | 35.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.966 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -130.9 | 34.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.620 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | G | -129.7 | 44.9 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | -130.5 | 38.2 | NA | NA | NA | ||||||||||||||
6t5q | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-10-14 | VAL | A:165 | A:165 | 0.0 | 0.0 | -126.8 | 45.1 | 0.0 | 0.0 | 0.0 |
HOH |
3.429 |
N |
O |
|||
VAL | B:165 | B:165 | 0.0 | 0.0 | G | -126.8 | 41.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.791 |
CG1 |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -126.8 | 42.8 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | G | -127.6 | 35.4 | NA | NA | NA | |||||||||||||
7puu | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -129.9 | 39.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.827 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -139.1 | 38.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.707 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -131.8 | 41.8 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | G | -133.8 | 37.5 | NA | NA | NA | |||||||||||||
7puv | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -121.6 | 31.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.986 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | G | -124.6 | 33.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.999 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | G | -127.9 | 25.4 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | G | -128.7 | 35.2 | NA | NA | NA | |||||||||||||
7puw | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | VAL | A:165 | A:165 | 0.0 | 0.0 | G | -129.8 | 40.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.645 |
N |
O |
||
VAL | B:165 | B:165 | 0.0 | 0.0 | S | -131.1 | 37.8 | 0.0 | 0.0 | 0.0 |
HOH |
3.661 |
N |
O |
|||||||||
VAL | C:165 | C:165 | 0.0 | 0.0 | S | -129.0 | 45.7 | NA | NA | NA | |||||||||||||
VAL | D:165 | D:165 | 0.0 | 0.0 | G | -130.9 | 39.0 | NA | NA | NA | |||||||||||||
6rps | 1 | O43570 | 96.7 | 0.0 |
X-RAY |
2019-11-13 | VAL | A:164 | A:167 | 0.0 | 0.0 | -129.7 | 42.0 | 0.0 | 0.0 | 0.0 |
HOH |
8.077 |
CG1 |
O |
|||
VAL | B:164 | B:167 | 0.0 | 0.0 | -130.7 | 42.7 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-o43570-f1 | 1 | O43570 | 100.0 | 0.0 | VAL | A:193 | A:193 | 0.0 | 0.0 | G | -123.0 | 32.7 |