Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr15 | 63637717 | . | C | A | CCDS10185.1:NM_001218.3:c.388Ggc>Tgc_NP_001209.1:p.130G>C | Homo sapiens carbonic anhydrase XII (CA12), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1jcz | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2001-08-17 | GLY | A:102 | A:104 | 0.0 | 0.0 | -112.4 | 28.4 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.180 3.678 |
O N |
ZN O |
|||
| GLY | B:102 | B:104 | 0.0 | 0.0 | -114.0 | 26.7 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.134 3.681 |
O N |
ZN O |
||||||||||
| 1jd0 | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2001-08-17 | GLY | A:102 | A:104 | 0.0 | 0.0 | -110.0 | 27.7 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.100 3.724 |
O N |
ZN O |
|||
| GLY | B:102 | B:104 | 0.0 | 0.0 | -117.0 | 29.2 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.132 3.682 |
O N |
ZN O |
||||||||||
| 6qn0 | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2020-02-26 | GLY | A:102 | A:104 | 0.0 | 0.0 | -119.6 | 24.0 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.060 4.085 |
O N |
ZN O |
|||
| GLY | B:102 | B:104 | 0.0 | 0.0 | -124.4 | 20.9 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.156 3.936 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:104 | 0.0 | 0.0 | -117.1 | 20.8 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:104 | 0.0 | 0.0 | -127.6 | 29.6 | NA | NA | NA | ||||||||||||||
| 6qng | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2020-03-04 | GLY | A:102 | A:104 | 0.0 | 0.0 | -122.5 | 13.6 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.092 3.944 |
O N |
ZN O |
|||
| GLY | B:102 | B:104 | 0.0 | 0.0 | -122.0 | 14.0 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.115 3.745 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:104 | 0.0 | 0.0 | -127.9 | 23.0 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:104 | 0.0 | 0.0 | -126.9 | 25.6 | NA | NA | NA | ||||||||||||||
| 6qnl | 1 | O43570 | 99.62 | 0.0 |
X-RAY |
2020-03-04 | GLY | A:102 | A:104 | 0.0 | 0.0 | -118.3 | 25.5 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.105 3.797 |
O N |
ZN O |
|||
| GLY | B:102 | B:104 | 0.0 | 0.0 | -119.2 | 23.6 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.098 4.030 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:104 | 0.0 | 0.0 | -107.1 | 12.4 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:104 | 0.0 | 0.0 | -129.3 | 26.3 | NA | NA | NA | ||||||||||||||
| 4ht2 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2013-04-10 | GLY | A:102 | A:102 | 0.0 | 0.0 | -135.0 | 29.9 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.214 3.730 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -118.0 | 29.7 | NA | NA | NA | ||||||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -128.4 | 25.7 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -121.1 | 28.2 | NA | NA | NA | ||||||||||||||
| 4kp5 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2013-11-06 | GLY | A:102 | A:102 | 0.0 | 0.0 | -114.9 | 22.6 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.199 3.802 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -125.1 | 27.3 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.173 4.074 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -123.3 | 35.1 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -118.7 | 25.8 | NA | NA | NA | ||||||||||||||
| 4kp8 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2013-11-06 | GLY | A:102 | A:102 | 0.0 | 0.0 | -117.5 | 30.9 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.186 3.646 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -117.2 | 28.7 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.260 3.745 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -122.5 | 37.0 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -118.7 | 28.7 | NA | NA | NA | ||||||||||||||
| 4q0l | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-01-28 | GLY | A:102 | A:102 | 0.0 | 0.0 | -128.5 | 27.4 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.024 3.658 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -129.6 | 21.5 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.015 3.826 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -131.0 | 24.7 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -130.1 | 25.0 | NA | NA | NA | ||||||||||||||
| 4qj0 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-04-15 | GLY | A:102 | A:102 | 0.0 | 0.0 | -116.4 | 23.6 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.173 3.813 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -119.9 | 26.6 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.147 4.038 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -122.5 | 26.8 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -114.3 | 18.9 | NA | NA | NA | ||||||||||||||
| 4qjo | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-04-15 | GLY | A:102 | A:102 | 0.0 | 0.0 | -126.3 | 33.8 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.074 3.678 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -127.0 | 31.9 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.085 3.796 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -116.6 | 25.3 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -126.7 | 33.3 | NA | NA | NA | ||||||||||||||
| 4qjw | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-04-15 | GLY | A:102 | A:102 | 0.0 | 0.0 | -122.1 | 24.0 | 0.0 | 0.0 | 0.0 |
ZN WWO HOH |
9.008 9.819 3.677 |
O O N |
ZN N10 O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -115.4 | 30.4 | 0.0 | 0.0 | 0.0 |
ZN WWO HOH |
9.035 9.922 3.723 |
O O N |
ZN N10 O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -121.5 | 24.4 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -120.1 | 27.1 | NA | NA | NA | ||||||||||||||
| 4ww8 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2015-07-01 | GLY | A:102 | A:102 | 0.0 | 0.0 | -113.3 | 26.2 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.124 3.802 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -118.8 | 26.1 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.144 4.063 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -119.7 | 29.2 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -113.2 | 23.4 | NA | NA | NA | ||||||||||||||
| 5ll5 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | GLY | A:102 | A:102 | 0.0 | 0.0 | -120.6 | 27.0 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.165 3.791 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -120.6 | 25.0 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.204 4.013 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -121.5 | 26.7 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -112.6 | 20.0 | NA | NA | NA | ||||||||||||||
| 5ll9 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | GLY | A:102 | A:102 | 0.0 | 0.0 | -113.5 | 25.2 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.191 3.848 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -117.5 | 26.5 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.207 4.014 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -122.0 | 31.4 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -113.6 | 24.2 | NA | NA | NA | ||||||||||||||
| 5llo | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | GLY | A:102 | A:102 | 0.0 | 0.0 | -122.3 | 26.8 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.063 3.781 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -121.8 | 26.8 | 0.0 | 0.0 | 0.0 |
ZN 5EF HOH |
9.033 9.986 4.024 |
O O N |
ZN N4 O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -124.1 | 25.7 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -115.3 | 18.1 | NA | NA | NA | ||||||||||||||
| 5llp | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2017-08-16 | GLY | A:102 | A:102 | 0.0 | 0.0 | -120.1 | 26.3 | 0.0 | 0.0 | 0.0 |
ZN 6Z9 HOH |
9.020 9.958 3.844 |
O O N |
ZN N29 O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -119.4 | 20.7 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.052 4.004 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -122.7 | 31.9 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -118.6 | 24.8 | NA | NA | NA | ||||||||||||||
| 5msa | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | GLY | A:102 | A:102 | 0.0 | 0.0 | -112.5 | 21.3 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.095 3.828 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -120.9 | 23.4 | 0.0 | 0.0 | 0.0 |
EDO ZN HOH |
9.101 9.141 4.040 |
N O N |
O1 ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -118.7 | 29.3 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -115.5 | 24.3 | NA | NA | NA | ||||||||||||||
| 5msb | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2018-01-17 | GLY | A:102 | A:102 | 0.0 | 0.0 | -117.0 | 23.7 | 0.0 | 0.0 | 0.0 |
ZN EDO HOH |
9.108 8.283 3.836 |
O CA N |
ZN O1 O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -119.8 | 25.7 | 0.0 | 0.0 | 0.0 |
ZN PEG HOH |
9.098 8.290 4.018 |
O N N |
ZN O1 O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -121.0 | 27.0 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -119.1 | 24.9 | NA | NA | NA | ||||||||||||||
| 6g5l | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2019-03-13 | GLY | A:102 | A:102 | 0.0 | 0.0 | -113.1 | 23.1 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.113 3.823 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -119.8 | 22.4 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.113 4.077 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -120.7 | 26.5 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -113.7 | 23.2 | NA | NA | NA | ||||||||||||||
| 6g7a | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2019-03-13 | GLY | A:102 | A:102 | 0.0 | 0.0 | -118.3 | 26.8 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.156 3.773 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -120.1 | 27.2 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.161 4.002 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -122.8 | 32.6 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -114.5 | 22.6 | NA | NA | NA | ||||||||||||||
| 6r6y | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | GLY | A:102 | A:102 | 0.0 | 0.0 | -116.2 | 26.2 | 0.0 | 0.0 | 0.0 |
ZN DMS HOH |
9.091 9.677 3.844 |
O N N |
ZN S O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -116.9 | 23.3 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.097 4.070 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -120.1 | 29.4 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -116.1 | 23.8 | NA | NA | NA | ||||||||||||||
| 6r71 | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-04-08 | GLY | A:102 | A:102 | 0.0 | 0.0 | -117.7 | 28.7 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.169 4.058 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -121.1 | 25.5 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.115 3.815 |
O N |
ZN O |
||||||||||
| 6t5p | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-10-14 | GLY | A:102 | A:102 | 0.0 | 0.0 | -120.6 | 30.1 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.108 3.818 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -122.5 | 27.1 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.135 4.057 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -128.9 | 35.9 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -118.3 | 26.3 | NA | NA | NA | ||||||||||||||
| 6t5q | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2020-10-14 | GLY | A:102 | A:102 | 0.0 | 0.0 | -130.1 | 35.5 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.124 4.001 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -124.7 | 33.0 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.137 3.944 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -134.6 | 24.3 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -134.2 | 24.8 | NA | NA | NA | ||||||||||||||
| 7puu | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | GLY | A:102 | A:102 | 0.0 | 0.0 | -113.8 | 24.8 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.083 3.805 |
O N |
ZN O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -118.1 | 25.1 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.106 4.024 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -122.3 | 28.9 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -117.3 | 23.3 | NA | NA | NA | ||||||||||||||
| 7puv | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | GLY | A:102 | A:102 | 0.0 | 0.0 | -116.4 | 19.8 | 0.0 | 0.0 | 0.0 |
ZN EDO EDO HOH |
9.199 6.120 8.100 3.790 |
O N CA N |
ZN O2 C2 O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -123.3 | 26.2 | 0.0 | 0.0 | 0.0 |
ZN HOH |
9.209 4.053 |
O N |
ZN O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -126.1 | 34.6 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -120.8 | 28.4 | NA | NA | NA | ||||||||||||||
| 7puw | 1 | O43570 | 100.0 | 0.0 |
X-RAY |
2022-01-12 | GLY | A:102 | A:102 | 0.0 | 0.0 | -115.2 | 23.7 | 0.0 | 0.0 | 0.0 |
ZN 84I HOH |
9.126 9.466 3.841 |
O O N |
ZN C15 O |
|||
| GLY | B:102 | B:102 | 0.0 | 0.0 | -116.6 | 24.4 | 0.0 | 0.0 | 0.0 |
ZN 84I HOH |
9.131 9.510 4.015 |
O O N |
ZN C15 O |
||||||||||
| GLY | C:102 | C:102 | 0.0 | 0.0 | -120.7 | 25.0 | NA | NA | NA | ||||||||||||||
| GLY | D:102 | D:102 | 0.0 | 0.0 | -117.8 | 22.8 | NA | NA | NA | ||||||||||||||
| 6rps | 1 | O43570 | 96.7 | 0.0 |
X-RAY |
2019-11-13 | GLY | A:101 | A:104 | 0.0 | 0.0 | -132.6 | 13.4 | 0.0 | 0.0 | 0.0 |
ZN CD HOH |
9.228 8.459 3.911 |
O N N |
ZN CD O |
|||
| GLY | B:101 | B:104 | 0.0 | 0.0 | -129.5 | 11.4 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o43570-f1 | 1 | O43570 | 100.0 | 0.0 | GLY | A:130 | A:130 | 0.0 | 0.0 | -127.6 | 34.5 | ||