wupsivus

Variant

Genome	Chromosome	Position	VCF ID	Ref	Alt	mRNA Change	mRNA Info
GRCh37	chr15	63637742	.	G	A	CCDS10185.1:NM_001218.3:c.363caC>caT_NP_001209.1:p.121H>H	Homo sapiens carbonic anhydrase XII (CA12), transcript variant 1, mRNA.

pdb_id	:
label_asym_id	:
label_seq_id	:
label_comp_id	:
auth_asym_id	:
auth_seq_id	:

alphafold_id	:
label_asym_id	:
label_seq_id	:
label_comp_id	:
auth_asym_id	:
auth_seq_id	:

PDB

Entity							Residue			Monomer					BioUnit				Ligand				View
PDB	Entity	Uniprot	Identity	Evalue	ExpMethod	Date	Name	Label	Auth	ASA	rASA	SS	φ	ψ	ASA	rASA	ΔASA	Interaction	Name	Distance	Atom(p)	Atom(l)	View
1jcz	1	O43570	99.62	0.0	X-RAY	2001-08-17	HIS	A:93	A:96	1.0	0.005	E	-136.3	137.4	1.0	0.005	0.0		ZN ACY HOH	2.091 4.332 2.919	NE2 NE2 NE2	ZN O O
1jcz	1	O43570	99.62	0.0	X-RAY	2001-08-17	HIS	B:93	B:96	1.0	0.005	E	-137.1	137.4	1.0	0.005	0.0		ZN ACY HOH	2.054 4.352 2.858	NE2 NE2 NE2	ZN O O
1jd0	1	O43570	99.62	0.0	X-RAY	2001-08-17	HIS	A:93	A:96	2.0	0.01	E	-137.0	136.9	2.0	0.01	0.0		ZN AZM HOH	2.035 3.331 3.615	NE2 NE2 CE1	ZN N1 O
1jd0	1	O43570	99.62	0.0	X-RAY	2001-08-17	HIS	B:93	B:96	2.0	0.01	E	-136.1	138.3	2.0	0.01	0.0		ZN AZM HOH	2.051 3.403 3.546	NE2 NE2 CE1	ZN N1 O
6qn0	1	O43570	99.62	0.0	X-RAY	2020-02-26	HIS	A:93	A:96	2.0	0.01	E	-134.2	134.5	2.0	0.01	0.0		ZN J8Q HOH	2.111 3.400 3.463	NE2 NE2 CE1	ZN N1 O
							HIS	B:93	B:96	2.0	0.01	E	-128.5	135.6	2.0	0.01	0.0		ZN J8Q HOH	2.085 3.425 3.730	NE2 NE2 CE1	ZN N1 O
							HIS	C:93	C:96	2.0	0.01	E	-131.4	139.1	NA	NA	NA
							HIS	D:93	D:96	2.0	0.01	E	-130.5	131.0	NA	NA	NA
6qng	1	O43570	99.62	0.0	X-RAY	2020-03-04	HIS	A:93	A:96	3.0	0.015	E	-128.5	142.7	3.0	0.015	0.0		ZN J95 HOH	2.033 3.426 3.866	NE2 NE2 CE1	ZN N1 O
							HIS	B:93	B:96	2.0	0.01	E	-136.7	135.8	2.0	0.01	0.0		ZN J95 HOH	1.973 3.513 3.697	NE2 NE2 CE1	ZN N1 O
							HIS	C:93	C:96	2.0	0.01	E	-134.3	138.4	NA	NA	NA
							HIS	D:93	D:96	3.0	0.015	E	-128.5	141.5	NA	NA	NA
6qnl	1	O43570	99.62	0.0	X-RAY	2020-03-04	HIS	A:93	A:96	2.0	0.01	E	-131.6	142.4	2.0	0.01	0.0		ZN J92 HOH	2.067 3.423 3.660	NE2 NE2 CE1	ZN N1 O
							HIS	B:93	B:96	2.0	0.01	E	-131.5	142.0	2.0	0.01	0.0		ZN J92 HOH	2.067 3.330 3.506	NE2 NE2 CE1	ZN N1 O
							HIS	C:93	C:96	2.0	0.01	E	-133.4	135.9	NA	NA	NA
							HIS	D:93	D:96	2.0	0.01	E	-127.9	137.2	NA	NA	NA
4ht2	1	O43570	100.0	0.0	X-RAY	2013-04-10	HIS	A:93	A:93	2.0	0.01	E	-133.6	141.6	2.0	0.01	0.0		ZN V50 PEG EDO HOH	2.055 3.367 7.499 3.638 3.654	NE2 NE2 CE1 CE1 CE1	ZN N23 O4 O2 O
							HIS	B:93	B:93	3.0	0.015	E	-132.5	144.2	NA	NA	NA
							HIS	C:93	C:93	3.0	0.015	E	-133.0	144.7	NA	NA	NA
							HIS	D:93	D:93	3.0	0.015	E	-132.9	142.6	NA	NA	NA
4kp5	1	O43570	100.0	0.0	X-RAY	2013-11-06	HIS	A:93	A:93	2.0	0.01	E	-132.9	139.4	2.0	0.01	0.0		ZN E1F EDO HOH	2.036 3.440 5.025 3.706	NE2 NE2 CE1 CE1	ZN N19 C1 O
							HIS	B:93	B:93	2.0	0.01	E	-129.2	141.5	2.0	0.01	0.0		ZN E1F EDO HOH	2.049 3.387 5.048 3.693	NE2 NE2 CE1 CE1	ZN N19 C2 O
							HIS	C:93	C:93	1.0	0.005	E	-129.6	138.3	NA	NA	NA
							HIS	D:93	D:93	2.0	0.01	E	-134.1	140.4	NA	NA	NA
4kp8	1	O43570	100.0	0.0	X-RAY	2013-11-06	HIS	A:93	A:93	2.0	0.01	E	-140.3	132.4	2.0	0.01	0.0		ZN E1G HOH	2.117 3.259 3.482	NE2 NE2 CE1	ZN N20 O
							HIS	B:93	B:93	3.0	0.015	E	-123.9	143.2	3.0	0.015	0.0		ZN E1G PEG HOH	2.099 3.226 4.414 3.573	NE2 NE2 CE1 CE1	ZN N20 O2 O
							HIS	C:93	C:93	2.0	0.01	E	-128.0	139.4	NA	NA	NA
							HIS	D:93	D:93	2.0	0.01	E	-135.5	144.8	NA	NA	NA
4q0l	1	O43570	100.0	0.0	X-RAY	2015-01-28	HIS	A:93	A:93	2.0	0.01	E	-129.2	153.4	2.0	0.01	0.0		ZN V14 HOH	2.130 3.247 6.397	NE2 CE1 O	ZN F12 O
							HIS	B:93	B:93	2.0	0.01	E	-137.9	147.5	2.0	0.01	0.0		ZN V14 HOH	2.297 3.268 6.038	NE2 NE2 O	ZN F12 O
							HIS	C:93	C:93	1.0	0.005	E	-126.7	153.3	NA	NA	NA
							HIS	D:93	D:93	1.0	0.005	E	-139.1	152.4	NA	NA	NA
4qj0	1	O43570	100.0	0.0	X-RAY	2015-04-15	HIS	A:93	A:93	2.0	0.01	E	-136.5	139.0	2.0	0.01	0.0		ZN WWX HOH	2.038 3.403 3.716	NE2 NE2 CE1	ZN N4 O
							HIS	B:93	B:93	2.0	0.01	E	-133.0	143.0	2.0	0.01	0.0		ZN WWX HOH	2.017 2.933 3.667	NE2 CE1 CE1	ZN F11 O
							HIS	C:93	C:93	2.0	0.01	E	-133.9	134.5	NA	NA	NA
							HIS	D:93	D:93	4.0	0.021	E	-135.0	138.4	NA	NA	NA
4qjo	1	O43570	100.0	0.0	X-RAY	2015-04-15	HIS	A:93	A:93	2.0	0.01	E	-137.0	140.3	2.0	0.01	0.0		ZN V1F HOH	2.053 3.263 3.703	NE2 CE1 CE1	ZN F12 O
							HIS	B:93	B:93	4.0	0.021	E	-125.7	139.7	4.0	0.021	0.0		ZN V1F HOH	2.079 3.201 3.484	NE2 NE2 CE1	ZN N10 O
							HIS	C:93	C:93	2.0	0.01	E	-132.4	143.2	NA	NA	NA
							HIS	D:93	D:93	2.0	0.01	E	-135.5	145.3	NA	NA	NA
4qjw	1	O43570	100.0	0.0	X-RAY	2015-04-15	HIS	A:93	A:93	2.0	0.01	E	-130.8	137.9	2.0	0.01	0.0		ZN WWO HOH	2.049 3.158 3.574	NE2 CE1 CE1	ZN F12 O
							HIS	B:93	B:93	1.0	0.005	E	-131.8	142.9	1.0	0.005	0.0		ZN WWO HOH	2.072 3.219 3.567	NE2 NE2 CE1	ZN N10 O
							HIS	C:93	C:93	3.0	0.015	E	-127.6	143.1	NA	NA	NA
							HIS	D:93	D:93	3.0	0.015	E	-125.8	147.0	NA	NA	NA
4ww8	1	O43570	100.0	0.0	X-RAY	2015-07-01	HIS	A:93	A:93	3.0	0.015	E	-133.2	145.2	3.0	0.015	0.0		ZN EDO VD9 HOH	2.041 4.557 3.337 3.654	NE2 CE1 NE2 CE1	ZN C1 N3 O
							HIS	B:93	B:93	2.0	0.01	E	-133.3	143.2	2.0	0.01	0.0		ZN EDO EDO VD9 HOH	2.029 4.433 8.964 3.291 3.661	NE2 CE1 CE1 NE2 CE1	ZN C2 O2 N3 O
							HIS	C:93	C:93	1.0	0.005	E	-131.6	136.7	NA	NA	NA
							HIS	D:93	D:93	1.0	0.005	E	-134.0	141.5	NA	NA	NA
5ll5	1	O43570	100.0	0.0	X-RAY	2017-08-16	HIS	A:93	A:93	3.0	0.015	E	-134.5	140.9	3.0	0.015	0.0		ZN 6YH EDO EDO HOH	1.997 3.297 4.540 8.960 3.662	NE2 NE2 CE1 CE1 CE1	ZN N10 C2 O2 O
							HIS	B:93	B:93	2.0	0.01	E	-128.9	143.2	2.0	0.01	0.0		ZN 6YH EDO EDO HOH	2.026 3.269 4.468 8.890 3.669	NE2 NE2 CE1 CE1 CE1	ZN N10 C2 O1 O
							HIS	C:93	C:93	2.0	0.01	E	-130.0	138.5	NA	NA	NA
							HIS	D:93	D:93	2.0	0.01	E	-130.4	140.9	NA	NA	NA
5ll9	1	O43570	100.0	0.0	X-RAY	2017-08-16	HIS	A:93	A:93	2.0	0.01	E	-135.5	140.0	2.0	0.01	0.0		ZN 6YQ EDO EDO HOH	2.003 3.388 5.189 9.059 3.675	NE2 NE2 CE1 CE1 CE1	ZN N10 C1 O2 O
							HIS	B:93	B:93	2.0	0.01	E	-134.2	141.6	2.0	0.01	0.0		ZN 6YQ SO4 EDO HOH	1.987 3.258 8.862 4.509 3.679	NE2 NE2 CE1 CE1 CE1	ZN N10 O3 C2 O
							HIS	C:93	C:93	1.0	0.005	E	-130.8	135.9	NA	NA	NA
							HIS	D:93	D:93	2.0	0.01	E	-134.7	141.7	NA	NA	NA
5llo	1	O43570	100.0	0.0	X-RAY	2017-08-16	HIS	A:93	A:93	2.0	0.01	E	-134.0	146.3	2.0	0.01	0.0		ZN 5EF HOH	2.072 3.064 3.601	NE2 CE1 CE1	ZN F11 O
							HIS	B:93	B:93	3.0	0.015	E	-137.3	143.7	3.0	0.015	0.0		ZN 5EF HOH	2.043 3.064 3.568	NE2 CE1 CE1	ZN F11 O
							HIS	C:93	C:93	1.0	0.005	E	-133.7	138.3	NA	NA	NA
							HIS	D:93	D:93	2.0	0.01	E	-134.1	141.5	NA	NA	NA
5llp	1	O43570	100.0	0.0	X-RAY	2017-08-16	HIS	A:93	A:93	3.0	0.015	E	-129.7	144.9	3.0	0.015	0.0		ZN 6Z9 HOH	2.001 3.034 3.636	NE2 CE1 CE1	ZN F5 O
							HIS	B:93	B:93	2.0	0.01	E	-130.9	144.6	2.0	0.01	0.0		ZN 6Z9 HOH	2.046 3.188 3.695	NE2 CE1 CE1	ZN F5 O
							HIS	C:93	C:93	1.0	0.005	E	-129.4	142.1	NA	NA	NA
							HIS	D:93	D:93	1.0	0.005	E	-130.5	143.1	NA	NA	NA
5msa	1	O43570	100.0	0.0	X-RAY	2018-01-17	HIS	A:93	A:93	1.0	0.005	E	-134.3	141.2	1.0	0.005	0.0		ZN 3TV HOH	1.988 3.256 3.625	NE2 NE2 CE1	ZN N2 O
							HIS	B:93	B:93	2.0	0.01	E	-132.1	141.6	2.0	0.01	0.0		ZN 3TV CIT HOH	2.012 3.225 8.431 3.582	NE2 NE2 CE1 CE1	ZN N2 O5 O
							HIS	C:93	C:93	1.0	0.005	E	-132.9	141.1	NA	NA	NA
							HIS	D:93	D:93	1.0	0.005	E	-134.0	139.9	NA	NA	NA
5msb	1	O43570	100.0	0.0	X-RAY	2018-01-17	HIS	A:93	A:93	2.0	0.01	E	-133.9	141.1	2.0	0.01	0.0		ZN V13 HOH	1.985 3.371 3.552	NE2 NE2 CE1	ZN N10 O
							HIS	B:93	B:93	0.0	0.0	E	-133.1	142.4	0.0	0.0	0.0		ZN V13 HOH	2.017 2.942 3.612	NE2 NE2 CE1	ZN N10 O
							HIS	C:93	C:93	2.0	0.01	E	-132.0	138.1	NA	NA	NA
							HIS	D:93	D:93	1.0	0.005	E	-131.7	140.0	NA	NA	NA
6g5l	1	O43570	100.0	0.0	X-RAY	2019-03-13	HIS	A:93	A:93	2.0	0.01	E	-133.6	142.7	2.0	0.01	0.0		ZN EM5 HOH	2.027 3.373 3.608	NE2 NE2 CE1	ZN N5 O
							HIS	B:93	B:93	1.0	0.005	E	-133.1	142.2	1.0	0.005	0.0		ZN EM5 EDO HOH	2.027 3.344 9.838 3.669	NE2 NE2 CE1 CE1	ZN N5 C2 O
							HIS	C:93	C:93	2.0	0.01	E	-129.2	138.8	NA	NA	NA
							HIS	D:93	D:93	1.0	0.005	E	-132.0	139.9	NA	NA	NA
6g7a	1	O43570	100.0	0.0	X-RAY	2019-03-13	HIS	A:93	A:93	2.0	0.01	E	-134.4	142.0	2.0	0.01	0.0		ZN EOQ HOH	2.017 3.350 3.641	NE2 NE2 CE1	ZN N5 O
							HIS	B:93	B:93	1.0	0.005	E	-129.4	141.7	1.0	0.005	0.0		ZN EOQ HOH	2.066 3.341 3.516	NE2 NE2 CE1	ZN N5 O
							HIS	C:93	C:93	1.0	0.005	E	-131.6	140.5	NA	NA	NA
							HIS	D:93	D:93	1.0	0.005	E	-132.4	142.9	NA	NA	NA
6r6y	1	O43570	100.0	0.0	X-RAY	2020-04-08	HIS	A:93	A:93	2.0	0.01	E	-132.2	143.8	2.0	0.01	0.0		ZN EA3 HOH	2.022 3.390 3.676	NE2 NE2 CE1	ZN N1 O
							HIS	B:93	B:93	1.0	0.005	E	-132.6	143.6	1.0	0.005	0.0		ZN EA3 HOH	2.037 3.327 3.657	NE2 NE2 CE1	ZN N1 O
							HIS	C:93	C:93	1.0	0.005	E	-130.2	142.7	NA	NA	NA
							HIS	D:93	D:93	2.0	0.01	E	-132.4	142.7	NA	NA	NA
6r71	1	O43570	100.0	0.0	X-RAY	2020-04-08	HIS	A:93	A:93	1.0	0.005	E	-132.2	140.8	1.0	0.005	0.0		ZN JTW HOH	1.997 3.288 3.670	NE2 NE2 CE1	ZN N1 O
6r71	1	O43570	100.0	0.0	X-RAY	2020-04-08	HIS	B:93	B:93	2.0	0.01	E	-133.2	133.5	2.0	0.01	0.0		ZN JTW HOH	1.996 3.205 3.588	NE2 NE2 CE1	ZN N1 O
6t5p	1	O43570	100.0	0.0	X-RAY	2020-10-14	HIS	A:93	A:93	2.0	0.01	E	-131.6	142.7	2.0	0.01	0.0		ZN VD8 HOH	2.018 3.162 3.758	NE2 NE2 CE1	ZN N8 O
							HIS	B:93	B:93	1.0	0.005	E	-132.4	141.5	1.0	0.005	0.0		ZN VD8 HOH	2.042 3.063 3.691	NE2 NE2 CE1	ZN N8 O
							HIS	C:93	C:93	1.0	0.005	E	-131.5	138.8	NA	NA	NA
							HIS	D:93	D:93	2.0	0.01	E	-134.3	140.4	NA	NA	NA
6t5q	1	O43570	100.0	0.0	X-RAY	2020-10-14	HIS	A:93	A:93	3.0	0.015	E	-135.0	140.1	3.0	0.015	0.0		ZN MKQ HOH	2.062 3.198 3.491	NE2 NE2 CE1	ZN N1 O
							HIS	B:93	B:93	2.0	0.01	E	-133.8	143.0	2.0	0.01	0.0		ZN MKQ HOH	2.045 3.246 3.428	NE2 NE2 CE1	ZN N1 O
							HIS	C:93	C:93	2.0	0.01	E	-127.9	141.8	NA	NA	NA
							HIS	D:93	D:93	1.0	0.005	E	-134.5	139.8	NA	NA	NA
7puu	1	O43570	100.0	0.0	X-RAY	2022-01-12	HIS	A:93	A:93	3.0	0.015	E	-136.7	142.8	3.0	0.015	0.0		ZN 84O HOH	2.013 3.354 3.713	NE2 NE2 CE1	ZN N14 O
							HIS	B:93	B:93	2.0	0.01	E	-135.4	141.3	2.0	0.01	0.0		ZN 84O HOH	2.036 3.266 3.704	NE2 NE2 CE1	ZN N14 O
							HIS	C:93	C:93	2.0	0.01	E	-130.4	140.6	NA	NA	NA
							HIS	D:93	D:93	1.0	0.005	E	-134.1	141.2	NA	NA	NA
7puv	1	O43570	100.0	0.0	X-RAY	2022-01-12	HIS	A:93	A:93	2.0	0.01	E	-133.5	146.5	2.0	0.01	0.0		ZN 84Z HOH	2.071 3.125 3.539	NE2 NE2 CE1	ZN N10 O
							HIS	B:93	B:93	2.0	0.01	E	-133.3	139.6	2.0	0.01	0.0		ZN 84Z HOH	2.084 3.143 3.610	NE2 NE2 CE1	ZN N10 O
							HIS	C:93	C:93	2.0	0.01	E	-130.9	138.4	NA	NA	NA
							HIS	D:93	D:93	1.0	0.005	E	-123.7	141.6	NA	NA	NA
7puw	1	O43570	100.0	0.0	X-RAY	2022-01-12	HIS	A:93	A:93	3.0	0.015	E	-133.6	141.6	3.0	0.015	0.0		ZN 84I HOH	2.050 3.180 3.702	NE2 NE2 CE1	ZN N10 O
							HIS	B:93	B:93	2.0	0.01	E	-132.1	143.1	2.0	0.01	0.0		ZN 84I HOH	2.067 3.156 3.718	NE2 NE2 CE1	ZN N10 O
							HIS	C:93	C:93	2.0	0.01	E	-130.8	138.4	NA	NA	NA
							HIS	D:93	D:93	2.0	0.01	E	-131.9	144.8	NA	NA	NA
6rps	1	O43570	96.7	0.0	X-RAY	2019-11-13	HIS	A:92	A:96	1.0	0.005	E	-130.6	138.8	1.0	0.005	0.0		ZN ACT HOH	2.043 4.130 2.899	NE2 NE2 NE2	ZN OXT O
6rps	1	O43570	96.7	0.0	X-RAY	2019-11-13	HIS	B:92	B:96	2.0	0.01	E	-130.5	138.7	NA	NA	NA

AlphaFold DB

Entity					Residue			Monomer					View
ID	Entity	Uniprot	Identity	Evalue	Name	Label	Auth	ASA	rASA	SS	φ	ψ	View
af-o43570-f1	1	O43570	100.0	0.0	HIS	A:121	A:121	2.0	0.01	E	-123.8	138.1

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