Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 66170198 . A C CCDS10212.1:NM_004663.4:c.335cAt>cCt_NP_004654.1:p.112H>P Homo sapiens RAB11A, member RAS oncogene family (RAB11A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5fbl 2 P62491 100.0 5e-164 X-RAY
 2016-12-28 HIS B:117 B:112 84.0 0.431 H -120.5 12.2 84.0 0.431 0.0
5fbq 2 P62491 100.0 5e-164 X-RAY
 2016-12-28 HIS B:117 B:112 90.0 0.462 H -120.5 13.0 90.0 0.462 0.0
5fbr 2 P62491 99.54 1e-162 X-RAY
 2016-12-28 HIS B:117 B:112 97.0 0.497 H -120.4 12.6 97.0 0.497 0.0
5fbv 2 P62491 99.54 1e-162 X-RAY
 2016-12-28 HIS B:117 B:112 85.0 0.436 H -122.0 12.4 85.0 0.436 0.0
5fbw 2 P62491 99.54 1e-162 X-RAY
 2016-12-28 HIS B:117 B:112 110.0 0.564 H -121.9 11.5 110.0 0.564 0.0
4d0l 2 P62491 99.54 2e-162 X-RAY
 2014-05-28 HIS B:115 B:112 89.0 0.456 H -120.9 11.8 89.0 0.456 0.0
HIS D:115 D:112 88.0 0.451 S -121.1 12.1 NA NA NA
HIS F:115 F:112 77.0 0.395 S -122.0 12.3 NA NA NA
4d0m 2 P62491 99.54 2e-162 X-RAY
 2014-05-28 HIS B:115 B:112 91.0 0.467 H -117.7 8.6 91.0 0.467 0.0
HIS D:115 D:112 88.0 0.451 H -118.4 9.5 88.0 0.451 0.0
HIS H:115 H:112 89.0 0.456 H -117.4 8.1 NA NA NA
HIS J:115 J:112 89.0 0.456 H -118.7 9.4 NA NA NA
HIS N:115 N:112 90.0 0.462 H -117.8 9.7 NA NA NA
HIS P:115 P:112 88.0 0.451 H -117.1 9.8 70.0 0.359 0.092 C:Q9UBF8:0.092
HIS R:115 R:112 91.0 0.467 H -118.0 9.3 NA NA NA
HIS T:115 T:112 89.0 0.456 H -117.6 8.8 89.0 0.456 0.0
HIS X:115 X:112 88.0 0.451 H -117.8 9.1 NA NA NA
HIS Z:115 Z:112 91.0 0.467 H -117.8 8.8 NA NA NA
HIS DA:115 d:112 90.0 0.462 H -117.1 8.5 NA NA NA
HIS HA:115 h:112 88.0 0.451 H -117.3 9.0 NA NA NA
5c46 2 P62491 99.54 2e-162 X-RAY
 2016-01-20 HIS B:115 F:112 94.0 0.482 H -115.0 2.1 94.0 0.482 0.0
5c4g 1 P62491 99.54 2e-162 X-RAY
 2016-01-20 HIS A:115 B:112 71.0 0.364 H -123.2 -24.9 71.0 0.364 0.0
5euq 1 P62491 99.54 2e-162 X-RAY
 2016-02-24 HIS A:115 B:112 73.0 0.374 H -113.1 -26.4 73.0 0.374 0.0
6djl 1 P62491 99.54 2e-162 X-RAY
 2018-09-26 HIS A:115 A:112 74.0 0.379 H -121.5 -15.5 74.0 0.379 0.0
HIS F:115 F:112 75.0 0.385 H -113.1 -13.0 NA NA NA
HIS G:115 G:112 76.0 0.39 H -120.6 -13.6 NA NA NA
HIS H:115 H:112 61.0 0.313 H -113.1 -20.3 NA NA NA
4ojk 1 Q15907 92.93 8e-135 X-RAY
 2014-08-06 HIS A:107 A:112 79.0 0.405 H -83.0 -26.9 79.0 0.405 0.0 HOH
 5.900
 CE1
 O
HIS B:107 B:112 96.0 0.492 H -113.2 9.7 NA NA NA
4uj4 1 P62491 98.92 3e-134 X-RAY
 2015-08-12 HIS A:111 A:112 92.0 0.472 H -102.2 -6.8 NA NA NA
HIS D:111 D:112 88.0 0.451 H -101.1 -6.8 88.0 0.451 0.0
HIS G:111 G:112 80.0 0.41 H -101.4 -7.8 80.0 0.41 0.0
HIS J:111 J:112 90.0 0.462 H -101.1 -4.9 NA NA NA
2f9l 1 Q15907 92.42 8e-134 X-RAY
 2006-04-04 HIS A:106 A:112 34.0 NA H -75.1 -18.9 34.0 NA NA HOH
 4.086
 O
 O
2f9m 1 Q15907 92.42 8e-134 X-RAY
 2006-04-04 HIS A:106 A:112 45.0 0.231 H -118.0 -25.4 45.0 0.231 0.0 NI
HOH
 2.017
2.559
 NE2
O
 NI
O
4uj3 1 P62491 98.38 1e-133 X-RAY
 2015-08-12 HIS A:113 A:112 93.0 0.477 H -102.2 -6.7 93.0 0.477 0.0
HIS D:113 D:112 86.0 0.441 H -101.1 -7.0 NA NA NA
HIS G:113 G:112 79.0 0.405 H -101.8 -7.9 NA NA NA
HIS J:113 J:112 93.0 0.477 H -101.2 -5.5 NA NA NA
HIS M:113 M:112 102.0 0.523 H -100.1 -7.6 NA NA NA
HIS P:113 P:112 91.0 0.467 H -101.0 -6.2 NA NA NA
HIS S:113 S:112 89.0 0.456 H -98.7 -8.1 NA NA NA
HIS V:113 V:112 102.0 0.523 H -101.3 -5.8 NA NA NA
4uj5 1 P62491 97.84 2e-132 X-RAY
 2015-08-12 HIS A:111 A:112 95.0 0.487 S -98.9 18.8 95.0 0.487 0.0 HOH
 8.537
 ND1
 O
HIS B:111 B:112 102.0 0.523 S -98.7 20.9 NA NA NA
4lwz 1 P62491 100.0 1e-129 X-RAY
 2013-11-20 HIS A:112 A:112 71.0 0.364 H -111.0 -24.5 71.0 0.364 0.0
HIS C:112 C:112 79.0 0.405 H -102.7 -23.6 NA NA NA
4lx0 1 P62491 100.0 1e-129 X-RAY
 2013-11-20 HIS A:112 A:112 80.0 0.41 H -113.3 -14.9 80.0 0.41 0.0 GOL
HOH
 8.214
3.388
 CE1
CE1
 O1
O
HIS C:112 C:112 81.0 0.415 H -100.2 13.5 NA NA NA
5jcz 1 P62491 100.0 1e-129 X-RAY
 2016-09-28 HIS A:114 A:112 38.0 0.195 H -117.9 -29.7 38.0 0.195 0.0 EDO
HOH
 7.848
2.557
 CD2
NE2
 O2
O
HIS D:114 D:112 39.0 0.2 H -122.8 -30.4 NA NA NA
HIS F:114 I:112 83.0 0.426 H -117.5 -44.1 NA NA NA
4c4p 1 P62491 100.0 6e-127 X-RAY
 2013-09-18 HIS A:112 A:112 61.0 0.313 H -132.2 -9.9 61.0 0.313 0.0 HOH
 2.810
 O
 O
6ixv 2 P62491 100.0 7e-127 X-RAY
 2019-03-20 HIS E:114 E:112 76.0 0.39 T -113.5 -44.3 76.0 0.39 0.0
HIS F:114 F:112 87.0 0.446 T -101.2 -46.8 NA NA NA
HIS G:114 G:112 81.0 0.415 T -107.2 -44.8 NA NA NA
HIS H:114 H:112 91.0 0.467 T -98.6 -46.9 NA NA NA
1oiv 1 P24410 100.0 3e-126 X-RAY
 2004-01-08 HIS A:130 A:112 83.0 0.426 H -126.2 -25.1 83.0 0.426 0.0 SO4
HOH
 9.441
4.774
 CE1
CD2
 O2
O
HIS B:130 B:112 84.0 0.431 H -134.8 -26.8 84.0 0.431 0.0 HOH
 2.835
 O
 O
2gzd 1 P62491 99.42 1e-125 X-RAY
 2006-08-15 HIS A:112 A:112 90.0 0.462 H -120.8 -39.8 90.0 0.462 0.0 HOH
 7.007
 CD2
 O
HIS B:112 B:112 64.0 0.328 H -122.4 -24.5 64.0 0.328 0.0 HOH
 2.858
 CE1
 O
2gzh 1 P62491 99.42 1e-125 X-RAY
 2006-08-15 HIS A:112 A:112 61.0 0.313 H -122.8 -26.8 61.0 0.313 0.0 MG
HOH
 8.119
3.128
 ND1
O
 MG
O
1oiw 1 P24410 99.42 6e-125 X-RAY
 2004-01-08 HIS A:130 A:112 65.0 0.333 H -117.7 -8.8 65.0 0.333 0.0 HOH
 2.699
 O
 O
1oix 1 P24410 99.42 6e-125 X-RAY
 2005-01-25 HIS A:130 A:112 65.0 0.333 H -119.7 -10.2 65.0 0.333 0.0 HOH
 2.649
 O
 O
2hv8 1 P62491 99.41 8e-123 X-RAY
 2006-11-21 HIS A:109 A:112 77.0 0.395 H -123.3 -15.4 77.0 0.395 0.0 HOH
 2.580
 ND1
 O
HIS C:109 B:112 90.0 0.462 H -123.7 -14.1 NA NA NA
HIS E:109 C:112 61.0 0.313 H -124.2 -14.5 NA NA NA
6iy1 3 P62491 100.0 1e-122 X-RAY
 2019-12-18 HIS F:107 F:112 89.0 0.456 H -111.4 -34.8 NA NA NA
1yzk 1 P62491 100.0 5e-122 X-RAY
 2005-07-26 HIS A:121 A:112 68.0 0.349 H -122.4 -4.9 68.0 0.349 0.0 HOH
 2.911
 O
 O
6iy1 2 P62491 100.0 1e-121 X-RAY
 2019-12-18 HIS D:106 D:112 70.0 0.359 H -110.9 -25.0 NA NA NA
5ez5 1 P62491 99.4 1e-121 X-RAY
 2016-12-07 HIS A:105 A:112 38.0 0.195 H -111.4 -19.5 38.0 0.195 0.0
HIS B:105 B:112 53.0 0.272 H -114.0 -20.1 53.0 0.272 0.0 HOH
 5.090
 O
 O
2d7c 1 P62491 99.4 1e-120 X-RAY
 2006-09-26 HIS A:106 A:112 63.0 0.323 T -135.1 -28.4 63.0 0.323 0.0 MES
HOH
 9.986
2.614
 N
O
 C2
O
HIS B:106 B:112 86.0 0.441 H -126.0 -26.5 NA NA NA
6iy1 1 P62491 100.0 3e-120 X-RAY
 2019-12-18 HIS A:104 A:112 74.0 0.379 H -119.7 -12.9 74.0 0.379 0.0 HOH
 3.740
 O
 O
HIS B:104 B:112 70.0 0.359 H -116.3 -34.1 NA NA NA
HIS C:104 C:112 74.0 0.379 H -119.6 -32.8 NA NA NA
HIS E:104 E:112 82.0 0.421 H -118.2 -8.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p62491-f1 1 P62491 100.0 3e-164 HIS A:112 A:112 98.0 0.503 H -130.1 -11.6
af-q15907-f1 1 Q15907 91.28 6e-146 HIS A:112 A:112 98.0 0.503 H -132.2 -20.7