Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67473597 . A C CCDS10222.1:NM_005902.3:c.677tAc>tCc_NP_005893.1:p.226Y>S Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
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label_comp_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 TYR A:28 A:268 77.0 0.335 -128.2 150.1 59.0 0.257 0.078 A:Q15796:0.078
 HOH
 3.502
 CA
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 TYR A:28 A:268 74.0 0.322 -132.7 144.8 34.0 0.148 0.174 B:P12755:0.13
A:Q15796:0.039
 GOL
HOH
 6.352
3.322
 C
N
 C3
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 TYR A:7 A:225 40.0 0.174 -75.6 140.4 7.0 0.03 0.144 B:O95405:0.143
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 TYR A:9 A:268 83.0 0.361 -119.7 144.1 71.0 0.309 0.052 E:Q15796:0.052
 HOH
 2.836
 OH
 O
TYR C:9 C:268 95.0 0.413 -136.5 147.7 78.0 0.339 0.074 A:Q15796:0.074
 HOH
 2.949
 OH
 O
TYR E:9 E:268 73.0 0.317 -127.2 147.2 63.0 0.274 0.043 C:Q15796:0.043
 HOH
 2.857
 N
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 TYR A:9 A:268 79.0 0.343 -132.5 146.8 64.0 0.278 0.065 E:Q15796:0.065
TYR C:9 C:268 88.0 0.383 -130.2 144.9 72.0 0.313 0.07 A:Q15796:0.07
TYR E:9 E:268 87.0 0.378 -127.4 145.3 68.0 0.296 0.082 C:Q15796:0.083
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 TYR A:9 A:226 140.0 0.609 -85.1 52.1 140.0 0.609 0.0 HOH
 8.834
 OH
 O
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 TYR A:9 A:268 79.0 0.343 -126.5 128.3 32.0 0.139 0.204 B:P12755:0.157
A:Q15796:0.043
 HOH
 3.545
 CA
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 TYR A:10 NA:NA DO NA DO DO DO NA NA NA
TYR B:10 NA:NA DO NA DO DO DO NA NA NA
TYR C:10 NA:NA DO NA DO DO DO NA NA NA
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 TYR A:8 A:268 28.0 0.122 -67.7 136.1 5.0 0.022 0.1 B:O95405:0.1
TYR C:8 C:268 47.0 0.204 -65.7 129.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 TYR A:226 A:226 39.0 0.17 -62.3 146.6
af-q15796-f1 1 Q15796 83.73 0.0 TYR A:268 A:268 43.0 0.187 -70.6 141.8