Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr15 67473634 . C A CCDS10222.1:NM_005902.3:c.714taC>taA_NP_005893.1:p.238Y>* Homo sapiens SMAD family member 3 (SMAD3), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 92.51 1e-157 X-RAY
 2002-02-06 TYR A:40 A:280 43.0 0.187 E -136.7 153.6 15.0 0.065 0.122 A:Q15796:0.122
 HOH
 2.832
 OH
 O
6zvq 1 Q15796 92.51 1e-157 X-RAY
 2021-06-09 TYR A:40 A:280 41.0 0.178 E -138.1 146.9 18.0 0.078 0.1 A:Q15796:0.1
 TAR
GOL
GOL
GOL
HOH
 7.734
9.999
6.990
3.166
2.682
 OH
N
OH
OH
OH
 O4
C3
HO1
O3
O
1mk2 1 P84022 100.0 4e-154 X-RAY
 2002-10-16 TYR A:19 A:237 42.0 0.183 E -144.3 147.2 42.0 0.183 0.0
6m64 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 TYR A:21 A:280 38.0 0.165 E -136.9 146.8 21.0 0.091 0.074 E:Q15796:0.074
 HOH
 2.996
 OH
 O
TYR C:21 C:280 38.0 0.165 E -135.8 149.8 25.0 0.109 0.056 A:Q15796:0.057
 HOH
 3.115
 OH
 O
TYR E:21 E:280 34.0 0.148 E -135.3 148.7 9.0 0.039 0.109 C:Q15796:0.109
 HOH
 2.677
 OH
 O
7co1 1 Q15796 96.1 6e-149 X-RAY
 2020-11-25 TYR A:21 A:280 46.0 0.2 E -132.8 146.8 11.0 0.048 0.152 E:Q15796:0.152
TYR C:21 C:280 46.0 0.2 E -133.4 146.5 22.0 0.096 0.104 A:Q15796:0.104
TYR E:21 E:280 50.0 0.217 E -133.0 146.8 13.0 0.057 0.16 C:Q15796:0.161
1u7f 1 P84022 100.0 2e-147 X-RAY
 2004-09-28 TYR A:11 A:238 48.0 0.209 E -139.0 152.6 13.0 0.057 0.152 B:Q13485:0.152
 HOH
 2.624
 OH
 O
TYR C:11 C:238 48.0 0.209 E -132.4 152.5 10.0 0.043 0.166 A:P84022:0.165
 HOH
 2.677
 OH
 O
5xoc 1 P84022 100.0 2e-147 X-RAY
 2018-03-28 TYR A:21 A:238 44.0 0.191 E -129.9 151.1 11.0 0.048 0.143 A:P84022:0.143
 HOH
 5.449
 N
 O
1mjs 1 P84022 100.0 9e-147 X-RAY
 2002-10-16 TYR A:10 A:237 44.0 0.191 E -137.6 149.9 44.0 0.191 0.0 HOH
 2.585
 OH
 O
1u7v 1 Q15796 96.97 6e-145 X-RAY
 2004-09-28 TYR A:11 A:280 47.0 0.204 E -138.0 152.5 16.0 0.07 0.134 C:Q13485:0.135
TYR B:11 C:280 48.0 0.209 E -125.5 160.1 10.0 0.043 0.166 A:Q15796:0.165
5xod 1 Q15796 97.46 3e-144 X-RAY
 2018-03-28 TYR A:21 A:280 44.0 0.191 E -130.8 151.0 15.0 0.065 0.126 A:Q15796:0.126
 HOH
 4.457
 OH
 O
5zoj 1 Q15796 97.46 4e-144 X-RAY
 2018-10-10 TYR A:22 A:280 46.0 0.2 E -125.8 157.9 16.0 0.07 0.13 C:Q15796:0.13
TYR B:22 B:280 48.0 0.209 E -125.9 157.9 14.0 0.061 0.148 A:Q15796:0.148
TYR C:22 C:280 40.0 0.174 E -125.6 157.1 8.0 0.035 0.139 B:Q15796:0.139
1dev 1 Q15796 97.45 9e-144 X-RAY
 2000-01-21 TYR A:20 A:280 46.0 0.2 E -138.9 149.5 46.0 0.2 0.0
TYR C:20 C:280 43.0 0.187 E -128.4 153.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p84022-f1 1 P84022 100.0 0.0 TYR A:238 A:238 34.0 0.148 E -136.1 143.0
af-q15796-f1 1 Q15796 83.73 0.0 TYR A:280 A:280 27.0 0.117 E -133.4 143.1